| http://purl.uniprot.org/citations/9603525 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9603525 | http://www.w3.org/2000/01/rdf-schema#comment | "Initiation of transcription of a gene from a core promoter region by RNA polymerase II requires the assembly of several initiation factors to form a preinitiation complex. Assembly of this complex is thought to be nucleated exclusively by the sequence-specific binding of the TFIID transcription factor complex, which is composed of the TATA-binding protein (TBP) and TBP-associated factors (TAF(II)s), to the different promoters. Here we isolate and characterize a new multiprotein complex that does not contain either TBP or a TBP-like factor but is composed of several TAF(II)s and other proteins. This complex can replace TFIID on both TATA-containing and TATA-lacking promoters in in vitro transcription assays. Moreover, an anti-TBP antibody that inhibits TBP- and TFIID-dependent transcription does not inhibit activity of this new complex. These results indicate that TBP-free RNA polymerase II mediated transcription may be able to occur in mammalian cells and that multiple preinitiation complexes may play an important role in regulating gene expression."xsd:string |
| http://purl.uniprot.org/citations/9603525 | http://purl.org/dc/terms/identifier | "doi:10.1038/30283"xsd:string |
| http://purl.uniprot.org/citations/9603525 | http://purl.uniprot.org/core/author | "Brand M."xsd:string |
| http://purl.uniprot.org/citations/9603525 | http://purl.uniprot.org/core/author | "Tora L."xsd:string |
| http://purl.uniprot.org/citations/9603525 | http://purl.uniprot.org/core/author | "Jacq X."xsd:string |
| http://purl.uniprot.org/citations/9603525 | http://purl.uniprot.org/core/author | "Wieczorek E."xsd:string |
| http://purl.uniprot.org/citations/9603525 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9603525 | http://purl.uniprot.org/core/name | "Nature"xsd:string |
| http://purl.uniprot.org/citations/9603525 | http://purl.uniprot.org/core/pages | "187-191"xsd:string |
| http://purl.uniprot.org/citations/9603525 | http://purl.uniprot.org/core/title | "Function of TAF(II)-containing complex without TBP in transcription by RNA polymerase II."xsd:string |
| http://purl.uniprot.org/citations/9603525 | http://purl.uniprot.org/core/volume | "393"xsd:string |
| http://purl.uniprot.org/citations/9603525 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9603525 |
| http://purl.uniprot.org/citations/9603525 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9603525 |
| http://purl.uniprot.org/uniprot/O15265#attribution-F97ED49853AFB09437771CA26BAECC91 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/9603525 |
| http://purl.uniprot.org/uniprot/Q14CW9#attribution-F97ED49853AFB09437771CA26BAECC91 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/9603525 |
| http://purl.uniprot.org/uniprot/Q9NPA8#attribution-F97ED49853AFB09437771CA26BAECC91 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/9603525 |
| http://purl.uniprot.org/uniprot/Q92830#attribution-F97ED49853AFB09437771CA26BAECC91 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/9603525 |
| http://purl.uniprot.org/uniprot/O75486#attribution-F97ED49853AFB09437771CA26BAECC91 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/9603525 |
| http://purl.uniprot.org/uniprot/O00268#attribution-C6B03F44FBB50580606609B01F6E7F6A | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/9603525 |
| http://purl.uniprot.org/uniprot/O00268#attribution-F97ED49853AFB09437771CA26BAECC91 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/9603525 |
| http://purl.uniprot.org/uniprot/Q16594#attribution-F97ED49853AFB09437771CA26BAECC91 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/9603525 |
| http://purl.uniprot.org/uniprot/O75529#attribution-F97ED49853AFB09437771CA26BAECC91 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/9603525 |
| http://purl.uniprot.org/uniprot/P49848#attribution-C6B03F44FBB50580606609B01F6E7F6A | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/9603525 |
| http://purl.uniprot.org/uniprot/P49848#attribution-F97ED49853AFB09437771CA26BAECC91 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/9603525 |