| http://purl.uniprot.org/citations/9642267 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9642267 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9642267 | http://www.w3.org/2000/01/rdf-schema#comment | "We have purified and biochemically characterized a multiprotein complex designated SWAP. In a DNA transfer assay, SWAP preferentially recombines ("swaps") sequences derived from Ig heavy chain switch regions. We identified four of the proteins in the SWAP complex: B23 (nucleophosmin), C23 (nucleolin), poly(ADP-ribose) polymerase (PARP), and SWAP-70. The first three are proteins known to be present in most cells. B23 promotes single-strand DNA reannealing and the formation of joint molecules in a D-loop assay between homologous, but also between Smu and Sgamma sequences. SWAP-70 is a novel protein of 70 kDa. Its cDNA was cloned and sequenced, and the protein was overexpressed in Escherichia coli. SWAP-70 protein expression was found only in B lymphocytes that had been induced to switch to various Ig isotypes and in switching B-cell lines. SWAP-70 is a nuclear protein, has a weak affinity for DNA, binds ATP, and forms specific, high affinity complexes with B23, C23, and poly(ADP-ribose) polymerase. These findings are consistent with SWAP being the long elusive "switch recombinase" and with SWAP-70 being the specific recruiting element that assembles the switch recombinase from universal components."xsd:string |
| http://purl.uniprot.org/citations/9642267 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.273.27.17025"xsd:string |
| http://purl.uniprot.org/citations/9642267 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.273.27.17025"xsd:string |
| http://purl.uniprot.org/citations/9642267 | http://purl.uniprot.org/core/author | "Wabl M."xsd:string |
| http://purl.uniprot.org/citations/9642267 | http://purl.uniprot.org/core/author | "Wabl M."xsd:string |
| http://purl.uniprot.org/citations/9642267 | http://purl.uniprot.org/core/author | "Jessberger R."xsd:string |
| http://purl.uniprot.org/citations/9642267 | http://purl.uniprot.org/core/author | "Jessberger R."xsd:string |
| http://purl.uniprot.org/citations/9642267 | http://purl.uniprot.org/core/author | "Borggrefe T."xsd:string |
| http://purl.uniprot.org/citations/9642267 | http://purl.uniprot.org/core/author | "Borggrefe T."xsd:string |
| http://purl.uniprot.org/citations/9642267 | http://purl.uniprot.org/core/author | "Akhmedov A.T."xsd:string |
| http://purl.uniprot.org/citations/9642267 | http://purl.uniprot.org/core/author | "Akhmedov A.T."xsd:string |
| http://purl.uniprot.org/citations/9642267 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9642267 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9642267 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/9642267 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/9642267 | http://purl.uniprot.org/core/pages | "17025-17035"xsd:string |
| http://purl.uniprot.org/citations/9642267 | http://purl.uniprot.org/core/pages | "17025-17035"xsd:string |
| http://purl.uniprot.org/citations/9642267 | http://purl.uniprot.org/core/title | "A B-cell-specific DNA recombination complex."xsd:string |
| http://purl.uniprot.org/citations/9642267 | http://purl.uniprot.org/core/title | "A B-cell-specific DNA recombination complex."xsd:string |
| http://purl.uniprot.org/citations/9642267 | http://purl.uniprot.org/core/volume | "273"xsd:string |
| http://purl.uniprot.org/citations/9642267 | http://purl.uniprot.org/core/volume | "273"xsd:string |
| http://purl.uniprot.org/citations/9642267 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9642267 |
| http://purl.uniprot.org/citations/9642267 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9642267 |