| http://purl.uniprot.org/citations/9768755 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9768755 | http://www.w3.org/2000/01/rdf-schema#comment | "The DNA-dependent protein kinase is a mammalian protein complex composed of Ku70, Ku80, and DNA-PKcs subunits that has been implicated in DNA double-strand break repair and V(D)J recombination. Here, by gene targeting, we have constructed a mouse with a disruption in the kinase domain of DNA-PKcs, generating an animal model completely devoid of DNA-PK activity. Our results demonstrate that DNA-PK activity is required for coding but not for signal join formation in mice. Although our DNA-PKcs defective mice closely resemble Scid mice, they differ by having elevated numbers of CD4+CD8+ thymocytes. This suggests that the Scid mice may not represent a null phenotype and may retain some residual DNA-PKcs function."xsd:string |
| http://purl.uniprot.org/citations/9768755 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1074-7613(00)80618-4"xsd:string |
| http://purl.uniprot.org/citations/9768755 | http://purl.uniprot.org/core/author | "Jackson S.P."xsd:string |
| http://purl.uniprot.org/citations/9768755 | http://purl.uniprot.org/core/author | "Gell D."xsd:string |
| http://purl.uniprot.org/citations/9768755 | http://purl.uniprot.org/core/author | "Herrera V.L."xsd:string |
| http://purl.uniprot.org/citations/9768755 | http://purl.uniprot.org/core/author | "Jeggo P.A."xsd:string |
| http://purl.uniprot.org/citations/9768755 | http://purl.uniprot.org/core/author | "Taccioli G.E."xsd:string |
| http://purl.uniprot.org/citations/9768755 | http://purl.uniprot.org/core/author | "Priestley A."xsd:string |
| http://purl.uniprot.org/citations/9768755 | http://purl.uniprot.org/core/author | "Amatucci A.G."xsd:string |
| http://purl.uniprot.org/citations/9768755 | http://purl.uniprot.org/core/author | "Beamish H.J."xsd:string |
| http://purl.uniprot.org/citations/9768755 | http://purl.uniprot.org/core/author | "Marshak Rothstein A."xsd:string |
| http://purl.uniprot.org/citations/9768755 | http://purl.uniprot.org/core/author | "Torres Arzayus M.I."xsd:string |
| http://purl.uniprot.org/citations/9768755 | http://purl.uniprot.org/core/author | "Xiang X.H."xsd:string |
| http://purl.uniprot.org/citations/9768755 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9768755 | http://purl.uniprot.org/core/name | "Immunity"xsd:string |
| http://purl.uniprot.org/citations/9768755 | http://purl.uniprot.org/core/pages | "355-366"xsd:string |
| http://purl.uniprot.org/citations/9768755 | http://purl.uniprot.org/core/title | "Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity."xsd:string |
| http://purl.uniprot.org/citations/9768755 | http://purl.uniprot.org/core/volume | "9"xsd:string |
| http://purl.uniprot.org/citations/9768755 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9768755 |
| http://purl.uniprot.org/citations/9768755 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9768755 |
| http://purl.uniprot.org/uniprot/P97313#attribution-973097E701799AA25D741DC55B9AD805 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/9768755 |
| http://purl.uniprot.org/uniprot/#_P97313-mappedCitation-9768755 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9768755 |
| http://purl.uniprot.org/uniprot/P97313 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/9768755 |