| http://purl.uniprot.org/citations/9806637 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9806637 | http://www.w3.org/2000/01/rdf-schema#comment | "A novel 75 kDa membrane protein, TIRC7, is described that exhibits a central role in T cell activation in vitro and in vivo. Modulation of TIRC7-mediated signals with specific anti-TIRC7 antibodies in vitro efficiently prevents human T cell proliferation and IL-2 secretion. Moreover, anti-TIRC7 antibodies specifically inhibit type 1 subset specific IFN-gamma expression but spare the type 2 cytokine IL-4. Diminished proliferation but not IFN-gamma secretion is reversible by exogenous rIL-2. An anti-TIRC7 antibody that cross-reacts with the 75 kDa rat homolog exhibits inhibition of rat alloimmune response in vitro and significantly prolongs kidney allograft survival in vivo. Targeting of TIRC7 may provide a novel therapeutic approach for modulation of the immune response."xsd:string |
| http://purl.uniprot.org/citations/9806637 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1074-7613(00)80634-2"xsd:string |
| http://purl.uniprot.org/citations/9806637 | http://purl.uniprot.org/core/author | "Robertson E.S."xsd:string |
| http://purl.uniprot.org/citations/9806637 | http://purl.uniprot.org/core/author | "Blumberg R.S."xsd:string |
| http://purl.uniprot.org/citations/9806637 | http://purl.uniprot.org/core/author | "Randall J."xsd:string |
| http://purl.uniprot.org/citations/9806637 | http://purl.uniprot.org/core/author | "Schulein R."xsd:string |
| http://purl.uniprot.org/citations/9806637 | http://purl.uniprot.org/core/author | "Kojima R."xsd:string |
| http://purl.uniprot.org/citations/9806637 | http://purl.uniprot.org/core/author | "Beinke S."xsd:string |
| http://purl.uniprot.org/citations/9806637 | http://purl.uniprot.org/core/author | "Gullans S.R."xsd:string |
| http://purl.uniprot.org/citations/9806637 | http://purl.uniprot.org/core/author | "Beato F."xsd:string |
| http://purl.uniprot.org/citations/9806637 | http://purl.uniprot.org/core/author | "Heinemann T."xsd:string |
| http://purl.uniprot.org/citations/9806637 | http://purl.uniprot.org/core/author | "Utku N."xsd:string |
| http://purl.uniprot.org/citations/9806637 | http://purl.uniprot.org/core/author | "Volk H.D."xsd:string |
| http://purl.uniprot.org/citations/9806637 | http://purl.uniprot.org/core/author | "Busconi L."xsd:string |
| http://purl.uniprot.org/citations/9806637 | http://purl.uniprot.org/core/author | "Bulwin G.C."xsd:string |
| http://purl.uniprot.org/citations/9806637 | http://purl.uniprot.org/core/author | "Milford E.L."xsd:string |
| http://purl.uniprot.org/citations/9806637 | http://purl.uniprot.org/core/author | "Tullius S.G."xsd:string |
| http://purl.uniprot.org/citations/9806637 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9806637 | http://purl.uniprot.org/core/name | "Immunity"xsd:string |
| http://purl.uniprot.org/citations/9806637 | http://purl.uniprot.org/core/pages | "509-518"xsd:string |
| http://purl.uniprot.org/citations/9806637 | http://purl.uniprot.org/core/title | "Prevention of acute allograft rejection by antibody targeting of TIRC7, a novel T cell membrane protein."xsd:string |
| http://purl.uniprot.org/citations/9806637 | http://purl.uniprot.org/core/volume | "9"xsd:string |
| http://purl.uniprot.org/citations/9806637 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9806637 |
| http://purl.uniprot.org/citations/9806637 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9806637 |