| http://purl.uniprot.org/citations/9808458 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9808458 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9808458 | http://www.w3.org/2000/01/rdf-schema#comment | "Homer is a neuronal immediate early gene (IEG) that is enriched at excitatory synapses and binds group 1 metabotropic glutamate receptors (mGluRs). Here, we characterize a family of Homer-related proteins derived from three distinct genes. Like Homer IEG (now termed Homer 1a), all new members bind group 1 mGluRs. In contrast to Homer 1a, new members are constitutively expressed and encode a C-terminal coiled-coil (CC) domain that mediates self-multimerization. CC-Homers form natural complexes that cross-link mGluRs and are enriched at the postsynaptic density. Homer 1a does not multimerize and blocks the association of mGluRs with CC-Homer complexes. These observations support a model in which the dynamic expression of Homer 1a competes with constitutively expressed CC-Homers to modify synaptic mGluR properties."xsd:string |
| http://purl.uniprot.org/citations/9808458 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0896-6273(00)80588-7"xsd:string |
| http://purl.uniprot.org/citations/9808458 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0896-6273(00)80588-7"xsd:string |
| http://purl.uniprot.org/citations/9808458 | http://purl.org/dc/terms/identifier | "doi:10.1016/S0896-6273(00)80588-7"xsd:string |
| http://purl.uniprot.org/citations/9808458 | http://purl.uniprot.org/core/author | "Xiao B."xsd:string |
| http://purl.uniprot.org/citations/9808458 | http://purl.uniprot.org/core/author | "Xiao B."xsd:string |
| http://purl.uniprot.org/citations/9808458 | http://purl.uniprot.org/core/author | "Ruggiero A."xsd:string |
| http://purl.uniprot.org/citations/9808458 | http://purl.uniprot.org/core/author | "Ruggiero A."xsd:string |
| http://purl.uniprot.org/citations/9808458 | http://purl.uniprot.org/core/author | "Worley P.F."xsd:string |
| http://purl.uniprot.org/citations/9808458 | http://purl.uniprot.org/core/author | "Worley P.F."xsd:string |
| http://purl.uniprot.org/citations/9808458 | http://purl.uniprot.org/core/author | "Lanahan A.A."xsd:string |
| http://purl.uniprot.org/citations/9808458 | http://purl.uniprot.org/core/author | "Lanahan A.A."xsd:string |
| http://purl.uniprot.org/citations/9808458 | http://purl.uniprot.org/core/author | "Petralia R.S."xsd:string |
| http://purl.uniprot.org/citations/9808458 | http://purl.uniprot.org/core/author | "Petralia R.S."xsd:string |
| http://purl.uniprot.org/citations/9808458 | http://purl.uniprot.org/core/author | "Doan A."xsd:string |
| http://purl.uniprot.org/citations/9808458 | http://purl.uniprot.org/core/author | "Doan A."xsd:string |
| http://purl.uniprot.org/citations/9808458 | http://purl.uniprot.org/core/author | "Wenthold R.J."xsd:string |
| http://purl.uniprot.org/citations/9808458 | http://purl.uniprot.org/core/author | "Wenthold R.J."xsd:string |
| http://purl.uniprot.org/citations/9808458 | http://purl.uniprot.org/core/author | "Tu J.C."xsd:string |
| http://purl.uniprot.org/citations/9808458 | http://purl.uniprot.org/core/author | "Tu J.C."xsd:string |
| http://purl.uniprot.org/citations/9808458 | http://purl.uniprot.org/core/author | "Yuan J.P."xsd:string |
| http://purl.uniprot.org/citations/9808458 | http://purl.uniprot.org/core/author | "Yuan J.P."xsd:string |
| http://purl.uniprot.org/citations/9808458 | http://purl.uniprot.org/core/author | "Breder C.D."xsd:string |