| http://purl.uniprot.org/citations/9814705 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9814705 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9814705 | http://www.w3.org/2000/01/rdf-schema#comment | "Kinase suppressor of ras (ksr) is required for efficient signal transmission within the RAS/MAPK cascade. A screen for mutations that modify a ksr-dependent phenotype identified a novel gene, connector enhancer of ksr (cnk), that functions upstream or in parallel to RAF in the RAS pathway. cnk encodes a protein containing several protein-protein interaction domains, suggesting that it brings different signaling molecules together. CNK is required in multiple receptor tyrosine kinase pathways where it appears to be a tyrosine phosphorylation target. Finally, CNK physically interacts with RAF and appears to localize to cell-cell contact regions. Together, these findings suggest that CNK is a novel component of a RAS-dependent signaling pathway that regulates RAF function and/or targets RAF to a specific subcellular compartment upon RAS activation."xsd:string |
| http://purl.uniprot.org/citations/9814705 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(00)81766-3"xsd:string |
| http://purl.uniprot.org/citations/9814705 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(00)81766-3"xsd:string |
| http://purl.uniprot.org/citations/9814705 | http://purl.org/dc/terms/identifier | "doi:10.1016/S0092-8674(00)81766-3"xsd:string |
| http://purl.uniprot.org/citations/9814705 | http://purl.uniprot.org/core/author | "Rubin G.M."xsd:string |
| http://purl.uniprot.org/citations/9814705 | http://purl.uniprot.org/core/author | "Rubin G.M."xsd:string |
| http://purl.uniprot.org/citations/9814705 | http://purl.uniprot.org/core/author | "Therrien M."xsd:string |
| http://purl.uniprot.org/citations/9814705 | http://purl.uniprot.org/core/author | "Therrien M."xsd:string |
| http://purl.uniprot.org/citations/9814705 | http://purl.uniprot.org/core/author | "Wong A.M."xsd:string |
| http://purl.uniprot.org/citations/9814705 | http://purl.uniprot.org/core/author | "Wong A.M."xsd:string |
| http://purl.uniprot.org/citations/9814705 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9814705 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9814705 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/9814705 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/9814705 | http://purl.uniprot.org/core/pages | "343-353"xsd:string |
| http://purl.uniprot.org/citations/9814705 | http://purl.uniprot.org/core/pages | "343-353"xsd:string |
| http://purl.uniprot.org/citations/9814705 | http://purl.uniprot.org/core/title | "CNK, a RAF-binding multidomain protein required for RAS signaling."xsd:string |
| http://purl.uniprot.org/citations/9814705 | http://purl.uniprot.org/core/title | "CNK, a RAF-binding multidomain protein required for RAS signaling."xsd:string |
| http://purl.uniprot.org/citations/9814705 | http://purl.uniprot.org/core/volume | "95"xsd:string |
| http://purl.uniprot.org/citations/9814705 | http://purl.uniprot.org/core/volume | "95"xsd:string |
| http://purl.uniprot.org/citations/9814705 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9814705 |
| http://purl.uniprot.org/citations/9814705 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9814705 |
| http://purl.uniprot.org/citations/9814705 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9814705 |