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http://purl.uniprot.org/citations/9837938http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9837938http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9837938http://www.w3.org/2000/01/rdf-schema#comment"Nuclear factor kappaB (NF-kappaB) and the Rel family of proteins are pleiotropic transcription factors that play central roles in the immune and inflammatory responses, as well as apoptosis. Here, we identified a serine/threonine protein phosphatase X (PPX; also called protein phosphatase 4 (PP4)) that specifically associated with c-Rel, NF-kappaB p50, and RelA. The amino acid sequences of human and mouse PPX are 100% identical, and the PPX gene was mapped to human chromosome 16 p11.2. Overexpression of PPX, but not catalytically inactive PPX mutants, stimulated the DNA-binding activity of c-Rel and activated NF-kappaB-mediated transcription. These results suggest that PPX is a novel activator of c-Rel/NF-kappaB."xsd:string
http://purl.uniprot.org/citations/9837938http://purl.org/dc/terms/identifier"doi:10.1074/jbc.273.50.33561"xsd:string
http://purl.uniprot.org/citations/9837938http://purl.org/dc/terms/identifier"doi:10.1074/jbc.273.50.33561"xsd:string
http://purl.uniprot.org/citations/9837938http://purl.uniprot.org/core/author"Mihindukulasuriya K.A."xsd:string
http://purl.uniprot.org/citations/9837938http://purl.uniprot.org/core/author"Mihindukulasuriya K.A."xsd:string
http://purl.uniprot.org/citations/9837938http://purl.uniprot.org/core/author"Wang Y.-P."xsd:string
http://purl.uniprot.org/citations/9837938http://purl.uniprot.org/core/author"Wang Y.-P."xsd:string
http://purl.uniprot.org/citations/9837938http://purl.uniprot.org/core/author"Hu M.C.-T."xsd:string
http://purl.uniprot.org/citations/9837938http://purl.uniprot.org/core/author"Hu M.C.-T."xsd:string
http://purl.uniprot.org/citations/9837938http://purl.uniprot.org/core/author"Tan T.-H."xsd:string
http://purl.uniprot.org/citations/9837938http://purl.uniprot.org/core/author"Tan T.-H."xsd:string
http://purl.uniprot.org/citations/9837938http://purl.uniprot.org/core/author"Qiu W.R."xsd:string
http://purl.uniprot.org/citations/9837938http://purl.uniprot.org/core/author"Qiu W.R."xsd:string
http://purl.uniprot.org/citations/9837938http://purl.uniprot.org/core/author"Afshar R."xsd:string
http://purl.uniprot.org/citations/9837938http://purl.uniprot.org/core/author"Afshar R."xsd:string
http://purl.uniprot.org/citations/9837938http://purl.uniprot.org/core/author"Tang-Oxley Q."xsd:string
http://purl.uniprot.org/citations/9837938http://purl.uniprot.org/core/author"Tang-Oxley Q."xsd:string
http://purl.uniprot.org/citations/9837938http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9837938http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9837938http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/9837938http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/9837938http://purl.uniprot.org/core/pages"33561-33565"xsd:string
http://purl.uniprot.org/citations/9837938http://purl.uniprot.org/core/pages"33561-33565"xsd:string