http://purl.uniprot.org/citations/9885563 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9885563 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9885563 | http://www.w3.org/2000/01/rdf-schema#comment | "Increasing evidence suggests that pre-mRNA splicing can take place cotranscriptionally in vivo. However, insight into how these two processes are linked has been lacking. Here, we describe that a novel transcriptional coactivator, p52, interacts not only with transcriptional activators and general transcription factors to enhance activated transcription but also with the essential splicing factor ASF/SF2 both in vitro and in vivo to modulate ASF/SF2-mediated pre-mRNA splicing. Furthermore, immunofluorescence studies indicate that the majority of endogenous p52 is colocalized with ASF/SF2 in the nucleoplasm of HeLa cells. Together, these observations suggest that, in addition to functioning as a transcriptional coactivator, p52 may also act as an adaptor to coordinate pre-mRNA splicing and transcriptional activation of class II genes."xsd:string |
http://purl.uniprot.org/citations/9885563 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1097-2765(00)80290-7"xsd:string |
http://purl.uniprot.org/citations/9885563 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1097-2765(00)80290-7"xsd:string |
http://purl.uniprot.org/citations/9885563 | http://purl.uniprot.org/core/author | "Si Y."xsd:string |
http://purl.uniprot.org/citations/9885563 | http://purl.uniprot.org/core/author | "Si Y."xsd:string |
http://purl.uniprot.org/citations/9885563 | http://purl.uniprot.org/core/author | "Ge H."xsd:string |
http://purl.uniprot.org/citations/9885563 | http://purl.uniprot.org/core/author | "Ge H."xsd:string |
http://purl.uniprot.org/citations/9885563 | http://purl.uniprot.org/core/author | "Wolffe A.P."xsd:string |
http://purl.uniprot.org/citations/9885563 | http://purl.uniprot.org/core/author | "Wolffe A.P."xsd:string |
http://purl.uniprot.org/citations/9885563 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
http://purl.uniprot.org/citations/9885563 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
http://purl.uniprot.org/citations/9885563 | http://purl.uniprot.org/core/name | "Mol. Cell"xsd:string |
http://purl.uniprot.org/citations/9885563 | http://purl.uniprot.org/core/name | "Mol. Cell"xsd:string |
http://purl.uniprot.org/citations/9885563 | http://purl.uniprot.org/core/pages | "751-759"xsd:string |
http://purl.uniprot.org/citations/9885563 | http://purl.uniprot.org/core/pages | "751-759"xsd:string |
http://purl.uniprot.org/citations/9885563 | http://purl.uniprot.org/core/title | "A novel transcriptional coactivator, p52, functionally interacts with the essential splicing factor ASF/SF2."xsd:string |
http://purl.uniprot.org/citations/9885563 | http://purl.uniprot.org/core/title | "A novel transcriptional coactivator, p52, functionally interacts with the essential splicing factor ASF/SF2."xsd:string |
http://purl.uniprot.org/citations/9885563 | http://purl.uniprot.org/core/volume | "2"xsd:string |
http://purl.uniprot.org/citations/9885563 | http://purl.uniprot.org/core/volume | "2"xsd:string |
http://purl.uniprot.org/citations/9885563 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9885563 |
http://purl.uniprot.org/citations/9885563 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9885563 |
http://purl.uniprot.org/citations/9885563 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9885563 |
http://purl.uniprot.org/citations/9885563 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9885563 |