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Literature citations Results

Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesis.

Berson J.F., Theos A.C., Harper D.C., Tenza D., Raposo G., Marks M.S.

J. Cell Biol. 161:521-533(2003) · UniProtKB (1) · Mapped (1)

Premelanosome amyloid-like fibrils are composed of only Golgi-processed forms of Pmel17 that have been proteolytically processed in endosomes.

Harper D.C., Theos A.C., Herman K.E., Tenza D., Raposo G., Marks M.S.

J. Biol. Chem. 283:2307-2322(2008) · UniProtKB (1) · Mapped (1)

Pmel17 initiates premelanosome morphogenesis within multivesicular bodies.

Berson J.F., Harper D.C., Tenza D., Raposo G., Marks M.S.

Mol. Biol. Cell 12:3451-3464(2001) · UniProtKB (2) · Mapped (1)

Phenotypic characterisation of RAB6A knockout mouse embryonic fibroblasts.

Bardin S., Miserey-Lenkei S., Hurbain I., Garcia-Castillo D., Raposo G., Goud B.

Biol. Cell 107:427-439(2015) · Mapped (4)

Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment.

Coumailleau F., Das V., Alcover A., Raposo G., Vandormael-Pournin S., Le Bras S., Baldacci P., Dautry-Varsat A., Babinet C., Cohen-Tannoudji M.

Mol. Biol. Cell 15:4444-4456(2004) · UniProtKB (3) · Mapped (52)

N-terminal domains elicit formation of functional Pmel17 amyloid fibrils.

Watt B., van Niel G., Fowler D.M., Hurbain I., Luk K.C., Stayrook S.E., Lemmon M.A., Raposo G., Shorter J., Kelly J.W. et al.

J. Biol. Chem. 284:35543-35555(2009) · Mapped (2)

NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells.

Savina A., Jancic C., Hugues S., Guermonprez P., Vargas P., Moura I.C., Lennon-Dumenil A.M., Seabra M.C., Raposo G., Amigorena S.

Cell 126:205-218(2006) · Mapped (8)

Myosin VI regulates actin dynamics and melanosome biogenesis.

Loubery S., Delevoye C., Louvard D., Raposo G., Coudrier E.

Traffic 13:665-680(2012) · Mapped (12)

Myosin VI and branched actin filaments mediate membrane constriction and fission of melanosomal tubule carriers.

Ripoll L., Heiligenstein X., Hurbain I., Domingues L., Figon F., Petersen K.J., Dennis M.K., Houdusse A., Marks M.S., Raposo G. et al.

J. Cell Biol. 217:2709-2726(2018) · Mapped (4)

Myosin Ib modulates the morphology and the protein transport within multi-vesicular sorting endosomes.

Salas-Cortes L., Ye F., Tenza D., Wilhelm C., Theos A., Louvard D., Raposo G., Coudrier E.

J. Cell. Sci. 118:4823-4832(2005) · Mapped (6)

Myosin 1b promotes the formation of post-Golgi carriers by regulating actin assembly and membrane remodelling at the trans-Golgi network.

Almeida C.G., Yamada A., Tenza D., Louvard D., Raposo G., Coudrier E.

Nat. Cell Biol. 13:779-789(2011) · Mapped (15)

Mutations in or near the transmembrane domain alter PMEL amyloid formation from functional to pathogenic.

Watt B., Tenza D., Lemmon M.A., Kerje S., Raposo G., Andersson L., Marks M.S.

PLoS Genet. 7:e1002286-e1002286(2011) · Mapped (2)

Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3).

Feldmann J., Callebaut I., Raposo G., Certain S., Bacq D., Dumont C., Lambert N., Ouachee-Chardin M., Chedville G., Tamary H. et al.

Cell 115:461-473(2003) · UniProtKB (1) · Mapped (1)

Multifocal structure of the T cell - dendritic cell synapse.

Brossard C., Feuillet V., Schmitt A., Randriamampita C., Romao M., Raposo G., Trautmann A.

Eur. J. Immunol. 35:1741-1753(2005) · Mapped (3)

Microphthalmia transcription factor induces both retinal pigmented epithelium and neural crest melanocytes from neuroretina cells.

Planque N., Raposo G., Leconte L., Anezo O., Martin P., Saule S.

J. Biol. Chem. 279:41911-41917(2004) · Mapped (7)

Metastasis suppressor tetraspanin CD82/KAI1 regulates ubiquitylation of epidermal growth factor receptor.

Odintsova E., van Niel G., Conjeaud H., Raposo G., Iwamoto R., Mekada E., Berditchevski F.

J. Biol. Chem. 288:26323-26334(2013) · Mapped (43)

Membrane trafficking. Nucleoside diphosphate kinases fuel dynamin superfamily proteins with GTP for membrane remodeling.

Boissan M., Montagnac G., Shen Q., Griparic L., Guitton J., Romao M., Sauvonnet N., Lagache T., Lascu I., Raposo G. et al.

Science 344:1510-1515(2014) · UniProtKB (1) · Mapped (48)

Loss of AP-3 function affects spontaneous and evoked release at hippocampal mossy fiber synapses.

Scheuber A., Rudge R., Danglot L., Raposo G., Binz T., Poncer J.C., Galli T.

Proc. Natl. Acad. Sci. U.S.A. 103:16562-16567(2006) · Mapped (9)

KIF13A mediates trafficking of influenza A virus ribonucleoproteins.

Ramos-Nascimento A., Kellen B., Ferreira F., Alenquer M., Vale-Costa S., Raposo G., Delevoye C., Amorim M.J.

J. Cell. Sci. 130:4038-4050(2017) · Mapped (2)

Involvement of caspase-cleaved and intact adaptor protein 1 complex in endosomal remodeling in maturing dendritic cells.

Santambrogio L., Potolicchio I., Fessler S.P., Wong S.H., Raposo G., Strominger J.L.

Nat. Immunol. 6:1020-1028(2005) · Mapped (3)

Intestinal epithelial cells secrete exosome-like vesicles.

van Niel G., Raposo G., Candalh C., Boussac M., Hershberg R., Cerf-Bensussan N., Heyman M.

Gastroenterology 121:337-349(2001)

Inhibition of nuclear import and cell-cycle progression by mutated forms of the dynamin-like GTPase MxB.

King M.C., Raposo G., Lemmon M.A.

Proc. Natl. Acad. Sci. U.S.A. 101:8957-8962(2004) · UniProtKB (1)

Inactivation of Pmel alters melanosome shape but has only a subtle effect on visible pigmentation.

Hellstrom A.R., Watt B., Fard S.S., Tenza D., Mannstrom P., Narfstrom K., Ekesten B., Ito S., Wakamatsu K., Larsson J. et al.

PLoS Genet. 7:e1002285-e1002285(2011) · Mapped (12)

Immature dendritic cells (DCs) use chemokines and intercellular adhesion molecule (ICAM)-1, but not DC-specific ICAM-3-grabbing nonintegrin, to stimulate CD4+ T cells in the absence of exogenous antigen.

Real E., Kaiser A., Raposo G., Amara A., Nardin A., Trautmann A., Donnadieu E.

J. Immunol. 173:50-60(2004) · Mapped (24)

Identification of a tight junction-associated guanine nucleotide exchange factor that activates Rho and regulates paracellular permeability.

Benais-Pont G., Punn A., Flores-Maldonado C., Eckert J., Raposo G., Fleming T.P., Cereijido M., Balda M.S., Matter K.

J. Cell Biol. 160:729-740(2003) · UniProtKB (2)

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