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Literature citations Results

Zscan4 restores the developmental potency of embryonic stem cells.

Amano T., Hirata T., Falco G., Monti M., Sharova L.V., Amano M., Sheer S., Hoang H.G., Piao Y., Stagg C.A. et al.

Nat Commun 4:1966-1966(2013) · Mapped (1)

Zscan4 is expressed specifically during late meiotic prophase in both spermatogenesis and oogenesis.

Ishiguro K.I., Monti M., Akiyama T., Kimura H., Chikazawa-Nohtomi N., Sakota M., Sato S., Redi C.A., Ko S.B., Ko M.S.

In Vitro Cell. Dev. Biol. Anim. 53:167-178(2017) · Mapped (1)

Wnt/beta-catenin and estrogen signaling converge in vivo.

Kouzmenko A.P., Takeyama K., Ito S., Furutani T., Sawatsubashi S., Maki A., Suzuki E., Kawasaki Y., Akiyama T., Tabata T. et al.

J. Biol. Chem. 279:40255-40258(2004) · Mapped (94)

Wnt signalling and the actin cytoskeleton.

Akiyama T., Kawasaki Y.

Oncogene 25:7538-7544(2006) · Mapped (40)

Wnt signaling regulates the sequential onset of neurogenesis and gliogenesis via induction of BMPs.

Kasai M., Satoh K., Akiyama T.

Genes Cells 10:777-783(2005) · Mapped (3)

Variable interactions between sucrose non-fermented 1-related protein kinases and regulatory proteins in higher plants.

Nozawa A., Sawada Y., Akiyama T., Koizumi N., Sano H.

Biosci. Biotechnol. Biochem. 67:2533-2540(2003) · Mapped (15)

Use of DNA arrays to identify a mutation in the negative regulator, csrR, responsible for the high virulence of a naturally occurring type M3 group A streptococcus clinical isolate.

Miyoshi-Akiyama T., Ikebe T., Watanabe H., Uchiyama T., Kirikae T., Kawamura Y.

J. Infect. Dis. 193:1677-1684(2006) · UniProtKB (2)

USAG-1: a bone morphogenetic protein antagonist abundantly expressed in the kidney.

Yanagita M., Oka M., Watabe T., Iguchi H., Niida A., Takahashi S., Akiyama T., Miyazono K., Yanagisawa M., Sakurai T.

Biochem. Biophys. Res. Commun. 316:490-500(2004) · UniProtKB (5) · Mapped (1)

Up-regulation of a BCL9-related beta-catenin-binding protein, B9L, in different stages of sporadic colorectal adenoma.

Sakamoto I., Ohwada S., Toya H., Togo N., Kashiwabara K., Oyama T., Nakajima T., Ito H., Adachi S., Jigami T. et al.

Cancer Sci. 98:83-87(2007) · UniProtKB (1)

Truncation mutations abolish chromatin-associated activities of adenomatous polyposis coli.

Kouzmenko A.P., Takeyama K., Kawasaki Y., Akiyama T., Kato S.

Oncogene 27:4888-4899(2008) · Mapped (40)

Transient ectopic expression of the histone demethylase JMJD3 accelerates the differentiation of human pluripotent stem cells.

Akiyama T., Wakabayashi S., Soma A., Sato S., Nakatake Y., Oda M., Murakami M., Sakota M., Chikazawa-Nohtomi N., Ko S.B. et al.

Development 143:3674-3685(2016) · Mapped (2)

Transcriptional regulation of the TGF-beta pseudoreceptor BAMBI by TGF-beta signaling.

Sekiya T., Oda T., Matsuura K., Akiyama T.

Biochem. Biophys. Res. Commun. 320:680-684(2004) · Mapped (17)

TRAF6 specifically contributes to FcepsilonRI-mediated cytokine production but not mast cell degranulation.

Yang Y.J., Chen W., Carrigan S.O., Chen W.M., Roth K., Akiyama T., Inoue J., Marshall J.S., Berman J.N., Lin T.J.

J. Biol. Chem. 283:32110-32118(2008) · Mapped (6)

TRAF6 negatively regulates the Jak1-Erk pathway in interleukin-2 signaling.

Motegi H., Shimo Y., Akiyama T., Inoue J.

Genes Cells 16:179-189(2011) · Mapped (22)

TRAF6 establishes innate immune responses by activating NF-kappaB and IRF7 upon sensing cytosolic viral RNA and DNA.

Konno H., Yamamoto T., Yamazaki K., Gohda J., Akiyama T., Semba K., Goto H., Kato A., Yujiri T., Imai T. et al.

PLoS ONE 4:e5674-e5674(2009) · Mapped (19)

TRAF6 directs commitment to regulatory T cells in thymocytes.

Shimo Y., Yanai H., Ohshima D., Qin J., Motegi H., Maruyama Y., Hori S., Inoue J., Akiyama T.

Genes Cells 16:437-447(2011) · Mapped (15)

TIFAB inhibits TIFA, TRAF-interacting protein with a forkhead-associated domain.

Matsumura T., Semba K., Azuma S., Ikawa S., Gohda J., Akiyama T., Inoue J.

Biochem. Biophys. Res. Commun. 317:230-234(2004) · UniProtKB (3)

Thr160 of Axin1 is critical for the formation and function of the beta-catenin destruction complex.

Koyama-Nasu R., Hayashi T., Nasu-Nishimura Y., Akiyama T., Yamanaka R.

Biochem. Biophys. Res. Commun. 459:411-415(2015) · Mapped (6)

Therapeutic potential of anti-interleukin-17A aptamer: suppression of interleukin-17A signaling and attenuation of autoimmunity in two mouse models.

Ishiguro A., Akiyama T., Adachi H., Inoue J., Nakamura Y.

Arthritis Rheum. 63:455-466(2011) · Mapped (2)

The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cells.

Hirabayashi Y., Itoh Y., Tabata H., Nakajima K., Akiyama T., Masuyama N., Gotoh Y.

Development 131:2791-2801(2004) · Mapped (1)

The Wilms tumor suppressor gene WT1 induces G1 arrest and apoptosis in myeloblastic leukemia M1 cells.

Murata Y., Kudoh T., Sugiyama H., Toyoshima K., Akiyama T.

FEBS Lett. 409:41-45(1997) · Mapped (10)

The tumour suppressor gene product APC blocks cell cycle progression from G0/G1 to S phase.

Baeg G.H., Matsumine A., Kuroda T., Bhattacharjee R.N., Miyashiro I., Toyoshima K., Akiyama T.

EMBO J. 14:5618-5625(1995)

The tumor suppressor protein APC colocalizes with beta-catenin in the colon epithelial cells.

Senda T., Miyashiro I., Matsumine A., Baeg G.H., Monden T., Kobayashil S., Monden M., Toyoshima K., Akiyama T.

Biochem. Biophys. Res. Commun. 223:329-334(1996) · Mapped (23)

The tumor suppressor LKB1 induces p21 expression in collaboration with LMO4, GATA-6, and Ldb1.

Setogawa T., Shinozaki-Yabana S., Masuda T., Matsuura K., Akiyama T.

Biochem. Biophys. Res. Commun. 343:1186-1190(2006) · Mapped (13)

The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance.

Akiyama T., Shimo Y., Yanai H., Qin J., Ohshima D., Maruyama Y., Asaumi Y., Kitazawa J., Takayanagi H., Penninger J.M. et al.

Immunity 29:423-437(2008) · Mapped (61)

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