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Literature citations Results

Thiol peroxidases ameliorate LRRK2 mutant-induced mitochondrial and dopaminergic neuronal degeneration in Drosophila.

Angeles D.C., Ho P., Chua L.L., Wang C., Yap Y.W., Ng C., Zhou Z.d., Lim K.L., Wszolek Z.K., Wang H.Y. et al.

Hum. Mol. Genet. 23:3157-3165(2014) · Mapped (8)

Phosphorylation of amyloid precursor protein by mutant LRRK2 promotes AICD activity and neurotoxicity in Parkinson's disease.

Chen Z.C., Zhang W., Chua L.L., Chai C., Li R., Lin L., Cao Z., Angeles D.C., Stanton L.W., Peng J.H. et al.

Sci. Signal. 10:0-0(2017) · UniProtKB (2) · Mapped (17)

Mutations in LRRK2 increase phosphorylation of peroxiredoxin 3 exacerbating oxidative stress-induced neuronal death.

Angeles D.C., Gan B.H., Onstead L., Zhao Y., Lim K.L., Dachsel J., Melrose H., Farrer M., Wszolek Z.K., Dickson D.W. et al.

Hum. Mutat. 32:1390-1397(2011) · UniProtKB (2) · Mapped (5)

MAP1B rescues LRRK2 mutant-mediated cytotoxicity.

Chan S.L., Chua L.L., Angeles D.C., Tan E.K.

Mol Brain 7:29-29(2014) · Mapped (16)

F-box protein 7 mutations promote protein aggregation in mitochondria and inhibit mitophagy.

Zhou Z.D., Xie S.P., Sathiyamoorthy S., Saw W.T., Sing T.Y., Ng S.H., Chua H.P., Tang A.M., Shaffra F., Li Z. et al.

Hum. Mol. Genet. 24:6314-6330(2015) · Mapped (10)

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