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Literature citations Results

VLHL plasminogen activator inhibitor spontaneously reactivates from the latent to active form.

Jankun J., Aleem A.M., Selman S.H., Basrur V., Skrzypczak-Jankun E.

Int. J. Mol. Med. 23:57-63(2009) · Mapped (1)

TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer.

Banerjee R., Russo N., Liu M., Basrur V., Bellile E., Palanisamy N., Scanlon C.S., van Tubergen E., Inglehart R.C., Metwally T. et al.

Nat Commun 5:4527-4527(2014) · Mapped (6)

The ubiquitin-conjugating enzyme (E2) Ube2w ubiquitinates the N terminus of substrates.

Scaglione K.M., Basrur V., Ashraf N.S., Konen J.R., Elenitoba-Johnson K.S., Todi S.V., Paulson H.L.

J. Biol. Chem. 288:18784-18788(2013) · UniProtKB (2)

The PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesis.

Muntean A.G., Tan J., Sitwala K., Huang Y., Bronstein J., Connelly J.A., Basrur V., Elenitoba-Johnson K.S., Hess J.L.

Cancer Cell 17:609-621(2010) · UniProtKB (3) · Mapped (21)

The interaction profile of homologous recombination repair proteins RAD51C, RAD51D and XRCC2 as determined by proteomic analysis.

Rajesh C., Gruver A.M., Basrur V., Pittman D.L.

Proteomics 9:4071-4086(2009) · Mapped (15)

The E3 ubiquitin ligase Itch inhibits p38alpha signaling and skin inflammation through the ubiquitylation of Tab1.

Theivanthiran B., Kathania M., Zeng M., Anguiano E., Basrur V., Vandergriff T., Pascual V., Wei W.Z., Massoumi R., Venuprasad K.

Sci Signal 8:ra22-ra22(2015) · Mapped (13)

SUMOylation of ROR-gammat inhibits IL-17 expression and inflammation via HDAC2.

Singh A.K., Khare P., Obaid A., Conlon K.P., Basrur V., DePinho R.A., Venuprasad K.

Nat Commun 9:4515-4515(2018) · Mapped (17)

Saccharomyces cerevisiae DNA ligase IV supports imprecise end joining independently of its catalytic activity.

Chiruvella K.K., Liang Z., Birkeland S.R., Basrur V., Wilson T.E.

PLoS Genet. 9:e1003599-e1003599(2013) · Mapped (2)

Regulation of the copper chaperone CCS by XIAP-mediated ubiquitination.

Brady G.F., Galban S., Liu X., Basrur V., Gitlin J.D., Elenitoba-Johnson K.S., Wilson T.E., Duckett C.S.

Mol. Cell. Biol. 30:1923-1936(2010) · UniProtKB (2) · Mapped (6)

Regulation of folate receptor internalization by protein kinase C alpha.

Elnakat H., Gonit M., Salazar M.D., Zhang J., Basrur V., Gunning W., Kamen B., Ratnam M.

Biochemistry 48:8249-8260(2009) · Mapped (7)

RBPJ/CBF1 interacts with L3MBTL3/MBT1 to promote repression of Notch signaling via histone demethylase KDM1A/LSD1.

Xu T., Park S.S., Giaimo B.D., Hall D., Ferrante F., Ho D.M., Hori K., Anhezini L., Ertl I., Bartkuhn M. et al.

EMBO J. 36:3232-3249(2017) · Mapped (41)

Pyrimidine tract-binding protein 1 mediates pyruvate kinase M2-dependent phosphorylation of signal transducer and activator of transcription 3 and oncogenesis in anaplastic large cell lymphoma.

Hwang S.R., Murga-Zamalloa C., Brown N., Basappa J., McDonnell S.R., Mendoza-Reinoso V., Basrur V., Wilcox R., Elenitoba-Johnson K., Lim M.S.

Lab. Invest. 97:962-970(2017) · Mapped (18)

Proteomic analysis of early melanosomes: identification of novel melanosomal proteins.

Basrur V., Yang F., Kushimoto T., Higashimoto Y., Yasumoto K., Valencia J., Muller J., Vieira W.D., Watabe H., Shabanowitz J. et al.

J. Proteome Res. 2:69-79(2003) · UniProtKB (29)

p38-mediated phosphorylation at T367 induces EZH2 cytoplasmic localization to promote breast cancer metastasis.

Anwar T., Arellano-Garcia C., Ropa J., Chen Y.C., Kim H.S., Yoon E., Grigsby S., Basrur V., Nesvizhskii A.I., Muntean A. et al.

Nat Commun 9:2801-2801(2018) · Mapped (14)

NPM-ALK signals through glycogen synthase kinase 3beta to promote oncogenesis.

McDonnell S.R., Hwang S.R., Basrur V., Conlon K.P., Fermin D., Wey E., Murga-Zamalloa C., Zeng Z., Zu Y., Elenitoba-Johnson K.S. et al.

Oncogene 31:3733-3740(2012) · Mapped (4)

Multiple interactions recruit MLL1 and MLL1 fusion proteins to the HOXA9 locus in leukemogenesis.

Milne T.A., Kim J., Wang G.G., Stadler S.C., Basrur V., Whitcomb S.J., Wang Z., Ruthenburg A.J., Elenitoba-Johnson K.S., Roeder R.G. et al.

Mol. Cell 38:853-863(2010) · Mapped (4)

Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer.

Brenner J.C., Ateeq B., Li Y., Yocum A.K., Cao Q., Asangani I.A., Patel S., Wang X., Liang H., Yu J. et al.

Cancer Cell 19:664-678(2011) · Mapped (32)

Loss of the Ubiquitin-conjugating Enzyme UBE2W Results in Susceptibility to Early Postnatal Lethality and Defects in Skin, Immune, and Male Reproductive Systems.

Wang B., Merillat S.A., Vincent M., Huber A.K., Basrur V., Mangelberger D., Zeng L., Elenitoba-Johnson K., Miller R.A., Irani D.N. et al.

J. Biol. Chem. 291:3030-3042(2016) · Mapped (4)

KRAS protein stability is regulated through SMURF2: UBCH5 complex-mediated beta-TrCP1 degradation.

Shukla S., Allam U.S., Ahsan A., Chen G., Krishnamurthy P.M., Marsh K., Rumschlag M., Shankar S., Whitehead C., Schipper M. et al.

Neoplasia 16:115-128(2014) · Mapped (24)

KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state.

Frescas D., Guardavaccaro D., Kuchay S.M., Kato H., Poleshko A., Basrur V., Elenitoba-Johnson K.S., Katz R.A., Pagano M.

Cell Cycle 7:3539-3547(2008) · UniProtKB (1) · Mapped (4)

Intrinsic disorder drives N-terminal ubiquitination by Ube2w.

Vittal V., Shi L., Wenzel D.M., Scaglione K.M., Duncan E.D., Basrur V., Elenitoba-Johnson K.S., Baker D., Paulson H.L., Brzovic P.S. et al.

Nat. Chem. Biol. 11:83-89(2015) · UniProtKB (1)

Integrated phosphoproteomic and metabolomic profiling reveals NPM-ALK-mediated phosphorylation of PKM2 and metabolic reprogramming in anaplastic large cell lymphoma.

McDonnell S.R., Hwang S.R., Rolland D., Murga-Zamalloa C., Basrur V., Conlon K.P., Fermin D., Wolfe T., Raskind A., Ruan C. et al.

Blood 122:958-968(2013) · Mapped (42)

Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase.

Bulavin D.V., Higashimoto Y., Popoff I.J., Gaarde W.A., Basrur V., Potapova O., Appella E., Fornace A.J. Jr.

Nature 411:102-107(2001) · UniProtKB (3)

IL-17-driven intestinal fibrosis is inhibited by Itch-mediated ubiquitination of HIC-5.

Paul J., Singh A.K., Kathania M., Elviche T.L., Zeng M., Basrur V., Theiss A.L., Venuprasad K.

Mucosal Immunol 11:427-436(2018) · Mapped (7)

Identification of novel proteins induced by estradiol, 4-hydroxytamoxifen and acolbifene in T47D breast cancer cells.

Al-Dhaheri M.H., Shah Y.M., Basrur V., Pind S., Rowan B.G.

Steroids 71:966-978(2006) · UniProtKB (1)

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