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Literature citations Results

Two E-selectin ligands, BST-2 and LGALS3BP, predict metastasis and poor survival of ER-negative breast cancer.

Woodman N., Pinder S.E., Tajadura V., Le Bourhis X., Gillett C., Delannoy P., Burchell J.M., Julien S.

Int. J. Oncol. 49:265-275(2016) · Mapped (15)

The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer.

Sewell R., Backstrom M., Dalziel M., Gschmeissner S., Karlsson H., Noll T., Gatgens J., Clausen H., Hansson G.C., Burchell J. et al.

J. Biol. Chem. 281:3586-3594(2006) · Mapped (4)

The lectin domain of UDP-N-acetyl-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase-T4 directs its glycopeptide specificities.

Hassan H., Reis C.A., Bennett E.P., Mirgorodskaya E., Roepstorff P., Hollingsworth M.A., Burchell J., Taylor-Papadimitriou J., Clausen H.

J. Biol. Chem. 275:38197-38205(2000) · UniProtKB (1)

T cells reactive with HLA-A*0201 peptides from the histone demethylase JARID1B are found in the circulation of breast cancer patients.

Coleman J.A., Correa I., Cooper L., Bohnenkamp H.R., Poulsom R., Burchell J.M., Taylor-Papadimitriou J.

Int. J. Cancer 128:2114-2124(2011) · Mapped (5,669)

Synergism of Toll-like receptor-induced interleukin-12p70 secretion by monocyte-derived dendritic cells is mediated through p38 MAPK and lowers the threshold of T-helper cell type 1 responses.

Bohnenkamp H.R., Papazisis K.T., Burchell J.M., Taylor-Papadimitriou J.

Cell. Immunol. 247:72-84(2007) · Mapped (7)

Substrate specificities of three members of the human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1, -T2, and -T3.

Wandall H.H., Hassan H., Mirgorodskaya E., Kristensen A.K., Roepstorff P., Bennett E.P., Nielsen P.A., Hollingsworth M.A., Burchell J., Taylor-Papadimitriou J. et al.

J. Biol. Chem. 272:23503-23514(1997) · UniProtKB (3) · Mapped (35)

Sialyl-Tn vaccine induces antibody-mediated tumour protection in a relevant murine model.

Julien S., Picco G., Sewell R., Vercoutter-Edouart A.S., Tarp M., Miles D., Clausen H., Taylor-Papadimitriou J., Burchell J.M.

Br. J. Cancer 100:1746-1754(2009) · Mapped (12)

Sialyl-Lewis(x) on P-selectin glycoprotein ligand-1 is regulated during differentiation and maturation of dendritic cells: a mechanism involving the glycosyltransferases C2GnT1 and ST3Gal I.

Julien S., Grimshaw M.J., Sutton-Smith M., Coleman J., Morris H.R., Dell A., Taylor-Papadimitriou J., Burchell J.M.

J. Immunol. 179:5701-5710(2007) · Mapped (10)

Selectin ligand sialyl-Lewis x antigen drives metastasis of hormone-dependent breast cancers.

Julien S., Ivetic A., Grigoriadis A., QiZe D., Burford B., Sproviero D., Picco G., Gillett C., Papp S.L., Schaffer L. et al.

Cancer Res. 71:7683-7693(2011) · Mapped (3)

Regulator of G-protein signaling 5 controls blood pressure homeostasis and vessel wall remodeling.

Holobotovskyy V., Manzur M., Tare M., Burchell J., Bolitho E., Viola H., Hool L.C., Arnolda L.F., McKitrick D.J., Ganss R.

Circ. Res. 112:781-791(2013) · Mapped (2)

Regulator of G protein signaling 5 is a determinant of gestational hypertension and preeclampsia.

Holobotovskyy V., Chong Y.S., Burchell J., He B., Phillips M., Leader L., Murphy T.V., Sandow S.L., McKitrick D.J., Charles A.K. et al.

Sci Transl Med 7:290ra88-290ra88(2015) · Mapped (2)

Protection against MUC1 expressing mouse tumours by intra-muscular injection of MUC1 cDNA requires functional CD8+ and CD4+ T cells but does not require the MUC1 tandem repeat domain.

Plunkett T., Graham R., Correa I., Sewell R., Miles D., Burchell J., Taylor-Papadimitriou J.

Int. J. Cancer 109:691-697(2004) · Mapped (3)

PLU-1/JARID1B/KDM5B is required for embryonic survival and contributes to cell proliferation in the mammary gland and in ER+ breast cancer cells.

Catchpole S., Spencer-Dene B., Hall D., Santangelo S., Rosewell I., Guenatri M., Beatson R., Scibetta A.G., Burchell J.M., Taylor-Papadimitriou J.

Int. J. Oncol. 38:1267-1277(2011) · Mapped (16)

PLU-1 nuclear protein, which is upregulated in breast cancer, shows restricted expression in normal human adult tissues: a new cancer/testis antigen?

Barrett A., Madsen B., Copier J., Lu P.J., Cooper L., Scibetta A.G., Burchell J., Taylor-Papadimitriou J.

Int. J. Cancer 101:581-588(2002) · UniProtKB (2) · Mapped (11)

PLU-1, a transcriptional repressor and putative testis-cancer antigen, has a specific expression and localisation pattern during meiosis.

Madsen B., Tarsounas M., Burchell J.M., Hall D., Poulsom R., Taylor-Papadimitriou J.

Chromosoma 112:124-132(2003) · UniProtKB (1)

Over-expression of ST3Gal-I promotes mammary tumorigenesis.

Picco G., Julien S., Brockhausen I., Beatson R., Antonopoulos A., Haslam S., Mandel U., Dell A., Pinder S., Taylor-Papadimitriou J. et al.

Glycobiology 20:1241-1250(2010) · Mapped (2)

Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin.

Gendler S.J., Lancaster C.A., Taylor-Papadimitriou J., Duhig T., Peat N., Burchell J., Pemberton L., Lalani E.-N., Wilson D.

J. Biol. Chem. 265:15286-15293(1990) · UniProtKB (1)

Functional conservation of subfamilies of putative UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferases in Drosophila, Caenorhabditis elegans, and mammals. One subfamily composed of l(2)35Aa is essential in Drosophila.

Schwientek T., Bennett E.P., Flores C., Thacker J., Hollmann M., Reis C.A., Behrens J., Mandel U., Keck B., Schaefer M.A. et al.

J. Biol. Chem. 277:22623-22638(2002) · UniProtKB (9) · Mapped (13)

Functional analysis of the transcription repressor PLU-1/JARID1B.

Scibetta A.G., Santangelo S., Coleman J., Hall D., Chaplin T., Copier J., Catchpole S., Burchell J., Taylor-Papadimitriou J.

Mol. Cell. Biol. 27:7220-7235(2007) · Mapped (12)

Evidence of recombination and positive selection in cetacean papillomaviruses.

Robles-Sikisaka R., Rivera R., Nollens H.H., St Leger J., Durden W.N., Stolen M., Burchell J., Wellehan J.F. Jr.

Virology 427:189-197(2012) · UniProtKB (28)

Endothelins induce CCR7 expression by breast tumor cells via endothelin receptor A and hypoxia-inducible factor-1.

Wilson J.L., Burchell J., Grimshaw M.J.

Cancer Res. 66:11802-11807(2006) · Mapped (4)

Cyclooxygenase-2 enzyme induces the expression of the alpha-2,3-sialyltransferase-3 (ST3Gal-I) in breast cancer.

Sproviero D., Julien S., Burford B., Taylor-Papadimitriou J., Burchell J.M.

J. Biol. Chem. 287:44490-44497(2012) · Mapped (7)

Crystal structure at 1.95 A resolution of the breast tumour-specific antibody SM3 complexed with its peptide epitope reveals novel hypervariable loop recognition.

Dokurno P., Bates P.A., Band H.A., Stewart L.M., Lally J.M., Burchell J.M., Taylor-Papadimitriou J., Snary D., Sternberg M.J., Freemont P.S.

J. Mol. Biol. 284:713-728(1998) · Mapped (3)

Cloning of a human UDP-N-acetyl-alpha-D-Galactosamine:polypeptide N-acetylgalactosaminyltransferase that complements other GalNAc-transferases in complete O-glycosylation of the MUC1 tandem repeat.

Bennett E.P., Hassan H., Mandel U., Mirgorodskaya E., Roepstorff P., Burchell J., Taylor-Papadimitriou J., Hollingsworth M.A., Merkx G., van Kessel A.G. et al.

J. Biol. Chem. 273:30472-30481(1998) · UniProtKB (1)

Characterisation and developmental expression of mouse Plu-1, a homologue of a human nuclear protein (PLU-1) which is specifically up-regulated in breast cancer.

Madsen B., Spencer-Dene B., Poulsom R., Hall D., Lu P.J., Scott K., Shaw A.T., Burchell J.M., Freemont P., Taylor-Papadimitriou J.

Mech. Dev. 119:S239-S246(2002) · UniProtKB (1) · Mapped (8)

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