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Literature citations Results

Virus-induced interferon alpha production by a dendritic cell subset in the absence of feedback signaling in vivo.

Barchet W., Cella M., Odermatt B., Asselin-Paturel C., Colonna M., Kalinke U.

J. Exp. Med. 195:507-516(2002) · Mapped (11)

Vav1 controls DAP10-mediated natural cytotoxicity by regulating actin and microtubule dynamics.

Graham D.B., Cella M., Giurisato E., Fujikawa K., Miletic A.V., Kloeppel T., Brim K., Takai T., Shaw A.S., Colonna M. et al.

J. Immunol. 177:2349-2355(2006) · UniProtKB (1) · Mapped (24)

Unique and redundant functions of NKp46+ ILC3s in models of intestinal inflammation.

Song C., Lee J.S., Gilfillan S., Robinette M.L., Newberry R.D., Stappenbeck T.S., Mack M., Cella M., Colonna M.

J. Exp. Med. 212:1869-1882(2015) · Mapped (24)

Tyrosine phosphorylation of a human killer inhibitory receptor recruits protein tyrosine phosphatase 1C.

Campbell K.S., Dessing M., Lopez-Botet M., Cella M., Colonna M.

J. Exp. Med. 184:93-100(1996) · Mapped (2)

Type I interferon negatively controls plasmacytoid dendritic cell numbers in vivo.

Swiecki M., Wang Y., Vermi W., Gilfillan S., Schreiber R.D., Colonna M.

J. Exp. Med. 208:2367-2374(2011) · Mapped (27)

Type I IFNs Regulate Inflammation, Vasculopathy, and Fibrosis in Chronic Cutaneous Graft-versus-Host Disease.

Delaney T.A., Morehouse C., Brohawn P.Z., Groves C., Colonna M., Yao Y., Sanjuan M., Coyle A.J.

J. Immunol. 197:42-50(2016) · Mapped (11)

Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response.

Swanson C.L., Wilson T.J., Strauch P., Colonna M., Pelanda R., Torres R.M.

J. Exp. Med. 207:1485-1500(2010) · Mapped (24)

Type I IFN controls chikungunya virus via its action on nonhematopoietic cells.

Schilte C., Couderc T., Chretien F., Sourisseau M., Gangneux N., Guivel-Benhassine F., Kraxner A., Tschopp J., Higgs S., Michault A. et al.

J. Exp. Med. 207:429-442(2010) · Mapped (58)

Triggering receptor expressed on myeloid cells-2 is involved in prion-induced microglial activation but does not contribute to prion pathogenesis in mouse brains.

Zhu C., Herrmann U.S., Li B., Abakumova I., Moos R., Schwarz P., Rushing E.J., Colonna M., Aguzzi A.

Neurobiol. Aging 36:1994-2003(2015) · Mapped (2)

Triggering receptor expressed on myeloid cells-1 (TREM-1) improves host defence in pneumococcal pneumonia.

Hommes T.J., Hoogendijk A.J., Dessing M.C., Van't Veer C., Florquin S., Colonna M., de Vos A.F., van der Poll T.

J. Pathol. 233:357-367(2014) · Mapped (2)

Triggering receptor expressed on myeloid cells 1 (TREM-1)-mediated Bcl-2 induction prolongs macrophage survival.

Yuan Z., Syed M.A., Panchal D., Joo M., Colonna M., Brantly M., Sadikot R.T.

J. Biol. Chem. 289:15118-15129(2014) · Mapped (5)

TREMs in the immune system and beyond.

Colonna M.

Nat. Rev. Immunol. 3:445-453(2003) · Mapped (2)

TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques.

Wang Y., Ulland T.K., Ulrich J.D., Song W., Tzaferis J.A., Hole J.T., Yuan P., Mahan T.E., Shi Y., Gilfillan S. et al.

J. Exp. Med. 213:667-675(2016) · Mapped (16)

TREM2 variants: new keys to decipher Alzheimer disease pathogenesis.

Colonna M., Wang Y.

Nat. Rev. Neurosci. 17:201-207(2016) · Mapped (3)

TREM2 triggers microglial density and age-related neuronal loss.

Linnartz-Gerlach B., Bodea L.G., Klaus C., Ginolhac A., Halder R., Sinkkonen L., Walter J., Colonna M., Neumann H.

Glia 67:539-550(2019) · UniProtKB (1) · Mapped (1)

TREM2 sustains microglial expansion during aging and response to demyelination.

Poliani P.L., Wang Y., Fontana E., Robinette M.L., Yamanishi Y., Gilfillan S., Colonna M.

J. Clin. Invest. 125:2161-2170(2015) · Mapped (2)

TREM-2 promotes macrophage survival and lung disease after respiratory viral infection.

Wu K., Byers D.E., Jin X., Agapov E., Alexander-Brett J., Patel A.C., Cella M., Gilfilan S., Colonna M., Kober D.L. et al.

J. Exp. Med. 212:681-697(2015) · Mapped (24)

TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis.

Kleinberger G., Yamanishi Y., Suarez-Calvet M., Czirr E., Lohmann E., Cuyvers E., Struyfs H., Pettkus N., Wenninger-Weinzierl A., Mazaheri F. et al.

Sci. Transl. Med. 6:243RA86-243RA86(2014) · UniProtKB (3) · Mapped (3)

TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease.

Ulland T.K., Song W.M., Huang S.C., Ulrich J.D., Sergushichev A., Beatty W.L., Loboda A.A., Zhou Y., Cairns N.J., Kambal A. et al.

Cell 170:649-663(2017) · UniProtKB (2) · Mapped (3)

TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model.

Wang Y., Cella M., Mallinson K., Ulrich J.D., Young K.L., Robinette M.L., Gilfillan S., Krishnan G.M., Sudhakar S., Zinselmeyer B.H. et al.

Cell 160:1061-1071(2015) · Mapped (6)

TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.

Yuan P., Condello C., Keene C.D., Wang Y., Bird T.D., Paul S.M., Luo W., Colonna M., Baddeley D., Grutzendler J.

Neuron 90:724-739(2016) · Mapped (9)

TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy.

Leyns C.E.G., Ulrich J.D., Finn M.B., Stewart F.R., Koscal L.J., Remolina Serrano J., Robinson G.O., Anderson E., Colonna M., Holtzman D.M.

Proc. Natl. Acad. Sci. U.S.A. 114:11524-11529(2017) · Mapped (2)

TREM2 and beta-catenin regulate bone homeostasis by controlling the rate of osteoclastogenesis.

Otero K., Shinohara M., Zhao H., Cella M., Gilfillan S., Colucci A., Faccio R., Ross F.P., Teitelbaum S.L., Takayanagi H. et al.

J. Immunol. 188:2612-2621(2012) · Mapped (15)

TREM-1-accentuated lung injury via miR-155 is inhibited by LP17 nanomedicine.

Yuan Z., Syed M., Panchal D., Joo M., Bedi C., Lim S., Onyuksel H., Rubinstein I., Colonna M., Sadikot R.T.

Am. J. Physiol. Lung Cell Mol. Physiol. 310:L426-38(2016) · Mapped (2)

TREM-1 amplifies inflammation and is a crucial mediator of septic shock.

Bouchon A., Facchetti F., Weigand M.A., Colonna M.

Nature 410:1103-1107(2001) · UniProtKB (1)

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