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Literature citations Results

The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells.

Galavotti S., Bartesaghi S., Faccenda D., Shaked-Rabi M., Sanzone S., McEvoy A., Dinsdale D., Condorelli F., Brandner S., Campanella M. et al.

Oncogene 32:699-712(2013) · Mapped (3)

TAp73 knockout mice show morphological and functional nervous system defects associated with loss of p75 neurotrophin receptor.

Niklison-Chirou M.V., Steinert J.R., Agostini M., Knight R.A., Dinsdale D., Cattaneo A., Mak T.W., Melino G.

Proc. Natl. Acad. Sci. U.S.A. 110:18952-18957(2013) · Mapped (10)

TAp73 is required for spermatogenesis and the maintenance of male fertility.

Inoue S., Tomasini R., Rufini A., Elia A.J., Agostini M., Amelio I., Cescon D., Dinsdale D., Zhou L., Harris I.S. et al.

Proc. Natl. Acad. Sci. U.S.A. 111:1843-1848(2014) · Mapped (19)

TAp73 depletion accelerates aging through metabolic dysregulation.

Rufini A., Niklison-Chirou M.V., Inoue S., Tomasini R., Harris I.S., Marino A., Federici M., Dinsdale D., Knight R.A., Melino G. et al.

Genes Dev. 26:2009-2014(2012) · Mapped (26)

Switching from aerobic glycolysis to oxidative phosphorylation modulates the sensitivity of mantle cell lymphoma cells to TRAIL.

Robinson G.L., Dinsdale D., Macfarlane M., Cain K.

Oncogene 31:4996-5006(2012) · Mapped (4)

RBM3 mediates structural plasticity and protective effects of cooling in neurodegeneration.

Peretti D., Bastide A., Radford H., Verity N., Molloy C., Martin M.G., Moreno J.A., Steinert J.R., Smith T., Dinsdale D. et al.

Nature 518:236-239(2015) · Mapped (5)

Protein domains, catalytic activity, and subcellular distribution of neuropathy target esterase in Mammalian cells.

Li Y., Dinsdale D., Glynn P.

J. Biol. Chem. 278:8820-8825(2003) · Mapped (1)

P73 and caspase-cleaved p73 fragments localize to mitochondria and augment TRAIL-induced apoptosis.

Sayan A.E., Sayan B.S., Gogvadze V., Dinsdale D., Nyman U., Hansen T.M., Zhivotovsky B., Cohen G.M., Knight R.A., Melino G.

Oncogene 27:4363-4372(2008) · Mapped (13)

p63 supports aerobic respiration through hexokinase II.

Viticchie G., Agostini M., Lena A.M., Mancini M., Zhou H., Zolla L., Dinsdale D., Saintigny G., Melino G., Candi E.

Proc. Natl. Acad. Sci. U.S.A. 112:11577-11582(2015) · Mapped (8)

Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability.

Robinson S.W., Bourgognon J.M., Spiers J.G., Breda C., Campesan S., Butcher A., Mallucci G.R., Dinsdale D., Morone N., Mistry R. et al.

PLoS Biol. 16:e2003611-e2003611(2018) · Mapped (13)

Neuropathy target esterase and its yeast homologue degrade phosphatidylcholine to glycerophosphocholine in living cells.

Zaccheo O., Dinsdale D., Meacock P.A., Glynn P.

J. Biol. Chem. 279:24024-24033(2004) · UniProtKB (2) · Mapped (6)

Loss of thymidine kinase 2 alters neuronal bioenergetics and leads to neurodegeneration.

Bartesaghi S., Betts-Henderson J., Cain K., Dinsdale D., Zhou X., Karlsson A., Salomoni P., Nicotera P.

Hum. Mol. Genet. 19:1669-1677(2010) · Mapped (6)

HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species.

Capasso M., Bhamrah M.K., Henley T., Boyd R.S., Langlais C., Cain K., Dinsdale D., Pulford K., Khan M., Musset B. et al.

Nat. Immunol. 11:265-272(2010) · Mapped (16)

Hepatobiliary damage and changes in hepatic gene expression caused by the antitumor drug ecteinascidin-743 (ET-743) in the female rat.

Donald S., Verschoyle R.D., Edwards R., Judah D.J., Davies R., Riley J., Dinsdale D., Lopez Lazaro L., Smith A.G., Gant T.W. et al.

Cancer Res. 62:4256-4262(2002) · Mapped (6)

Hepatic gene expression in protoporphyic Fech mice is associated with cholestatic injury but not a marked depletion of the heme regulatory pool.

Davies R., Schuurman A., Barker C.R., Clothier B., Chernova T., Higginson F.M., Judah D.J., Dinsdale D., Edwards R.E., Greaves P. et al.

Am. J. Pathol. 166:1041-1053(2005) · Mapped (14)

Genetic analysis of mitochondrial protein misfolding in Drosophila melanogaster.

Pimenta de Castro I., Costa A.C., Lam D., Tufi R., Fedele V., Moisoi N., Dinsdale D., Deas E., Loh S.H., Martins L.M.

Cell Death Differ. 19:1308-1316(2012) · Mapped (24)

FLASH is an essential component of Cajal bodies.

Barcaroli D., Dinsdale D., Neale M.H., Bongiorno-Borbone L., Ranalli M., Munarriz E., Sayan A.E., McWilliam J.M., Smith T.M., Fava E. et al.

Proc. Natl. Acad. Sci. U.S.A. 103:14802-14807(2006) · Mapped (3)

Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson's disease.

Tufi R., Gandhi S., de Castro I.P., Lehmann S., Angelova P.R., Dinsdale D., Deas E., Plun-Favreau H., Nicotera P., Abramov A.Y. et al.

Nat. Cell Biol. 16:157-166(2014) · Mapped (32)

Drosophila ref(2)P is required for the parkin-mediated suppression of mitochondrial dysfunction in pink1 mutants.

de Castro I.P., Costa A.C., Celardo I., Tufi R., Dinsdale D., Loh S.H., Martins L.M.

Cell Death Dis 4:e873-e873(2013) · Mapped (19)

Differential roles of p63 isoforms in epidermal development: selective genetic complementation in p63 null mice.

Candi E., Rufini A., Terrinoni A., Dinsdale D., Ranalli M., Paradisi A., De Laurenzi V., Spagnoli L.G., Catani M.V., Ramadan S. et al.

Cell Death Differ. 13:1037-1047(2006) · Mapped (6)

DEDD regulates degradation of intermediate filaments during apoptosis.

Lee J.C., Schickling O., Stegh A.H., Oshima R.G., Dinsdale D., Cohen G.M., Peter M.E.

J. Cell Biol. 158:1051-1066(2002) · UniProtKB (2)

Cytoplasmic function of mutant promyelocytic leukemia (PML) and PML-retinoic acid receptor-alpha.

Bellodi C., Kindle K., Bernassola F., Dinsdale D., Cossarizza A., Melino G., Heery D., Salomoni P.

J. Biol. Chem. 281:14465-14473(2006) · Mapped (10)

CYP4B1 activates 4-ipomeanol in rat lung.

Verschoyle R.D., Philpot R.M., Wolf C.R., Dinsdale D.

Toxicol. Appl. Pharmacol. 123:193-198(1993) · Mapped (1)

A cytoplasmic PML mutant inhibits p53 function.

Bellodi C., Kindle K., Bernassola F., Cossarizza A., Dinsdale D., Melino G., Heery D., Salomoni P.

Cell Cycle 5:2688-2692(2006) · Mapped (10)

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