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Literature citations Results

The two DNA clamps Rad9/Rad1/Hus1 complex and proliferating cell nuclear antigen differentially regulate flap endonuclease 1 activity.

Friedrich-Heineken E., Toueille M., Taennler B., Buerki C., Ferrari E., Hottiger M.O., Huebscher U.

J. Mol. Biol. 353:980-989(2005) · UniProtKB (3) · Mapped (9)

The human Rad9/Rad1/Hus1 damage sensor clamp interacts with DNA polymerase beta and increases its DNA substrate utilisation efficiency: implications for DNA repair.

Toueille M., El-Andaloussi N., Frouin I., Freire R., Funk D., Shevelev I., Friedrich-Heineken E., Villani G., Hottiger M.O., Huebscher U.

Nucleic Acids Res. 32:3316-3324(2004) · UniProtKB (3) · Mapped (3)

The human DNA polymerase lambda interacts with PCNA through a domain important for DNA primer binding and the interaction is inhibited by p21/WAF1/CIP1.

Maga G., Blanca G., Shevelev I., Frouin I., Ramadan K., Spadari S., Villani G., Huebscher U.

FASEB J. 18:1743-1745(2004) · UniProtKB (1) · Mapped (12)

The human checkpoint sensor and alternative DNA clamp Rad9-Rad1-Hus1 modulates the activity of DNA ligase I, a component of the long-patch base excision repair machinery.

Smirnova E., Toueille M., Markkanen E., Huebscher U.

Biochem. J. 389:13-17(2005) · UniProtKB (3) · Mapped (10)

Replication factor C interacts with the C-terminal side of proliferating cell nuclear antigen.

Mossi R., Jonsson Z.O., Allen B.L., Hardin S.H., Huebscher U.

J. Biol. Chem. 272:1769-1776(1997) · UniProtKB (3) · Mapped (1)

Replication factor C from the hyperthermophilic archaeon Pyrococcus abyssi does not need ATP hydrolysis for clamp-loading and contains a functionally conserved RFC PCNA-binding domain.

Henneke G., Gueguen Y., Flament D., Azam P., Querellou J., Dietrich J., Huebscher U., Raffin J.-P.

J. Mol. Biol. 323:795-810(2002) · UniProtKB (2)

Mutagenesis of human DNA polymerase lambda: essential roles of Tyr505 and Phe506 for both DNA polymerase and terminal transferase activities.

Shevelev I., Blanca G., Villani G., Ramadan K., Spadari S., Huebscher U., Maga G.

Nucleic Acids Res. 31:6916-6925(2003) · UniProtKB (1) · Mapped (12)

Mediation of proliferating cell nuclear antigen (PCNA)-dependent DNA replication through a conserved p21(Cip1)-like PCNA-binding motif present in the third subunit of human DNA polymerase delta.

Ducoux M., Urbach S., Baldacci G., Huebscher U., Koundrioukoff S., Christensen J., Hughes P.

J. Biol. Chem. 276:49258-49266(2001) · UniProtKB (4)

Mammalian DNA nucleotide excision repair reconstituted with purified protein components.

Aboussekhra A., Biggerstaff M., Shivji M.K., Vilpo J.A., Moncollin V., Podust V.N., Protic M., Huebscher U., Egly J.M., Wood R.D.

Cell 80:859-868(1995) · UniProtKB (3)

Human DNA polymerase lambda diverged in evolution from DNA polymerase beta toward specific Mn(++) dependence: a kinetic and thermodynamic study.

Blanca G., Shevelev I., Ramadan K., Villani G., Spadari S., Huebscher U., Maga G.

Biochemistry 42:7467-7476(2003) · UniProtKB (1)

Colocalization of human Rad17 and PCNA in late S phase of the cell cycle upon replication block.

Dahm K., Huebscher U.

Oncogene 21:7710-7719(2002) · UniProtKB (1)

Cloning of a mouse cDNA encoding DNA polymerase delta: refinement of the homology boxes.

Cullmann G., Hindges R., Berchtold M.W., Huebscher U.

Gene 134:191-200(1993) · UniProtKB (1) · Mapped (4)

Cloning, chromosomal localization, and interspecies interaction of mouse DNA polymerase delta small subunit (PolD2).

Hindges R., Huebscher U.

Genomics 44:45-51(1997) · UniProtKB (1) · Mapped (1)

Arginine methylation regulates DNA polymerase beta.

El-Andaloussi N., Valovka T., Toueille M., Steinacher R., Focke F., Gehrig P., Covic M., Hassa P.O., Schaer P., Huebscher U. et al.

Mol. Cell 22:51-62(2006) · UniProtKB (2)

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