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Literature citations Results

X-ray structure and inhibition of the feline infectious peritonitis virus 3C-like protease: Structural implications for drug design.

St John S.E., Therkelsen M.D., Nyalapatla P.R., Osswald H.L., Ghosh A.K., Mesecar A.D.

Bioorg. Med. Chem. Lett. 25:5072-5077(2015) · Mapped (1)

X-Ray Structure and Inhibition of 3C-like Protease from Porcine Epidemic Diarrhea Virus.

St John S.E., Anson B.J., Mesecar A.D.

Sci Rep 6:25961-25961(2016) · UniProtKB (1)

Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction.

Wain L.V., Sayers I., Soler Artigas M., Portelli M.A., Zeggini E., Obeidat M., Sin D.D., Bosse Y., Nickle D., Brandsma C.A. et al.

PLoS Genet. 10:e1004314-e1004314(2014) · Mapped (1)

Visual impairment in an optineurin mouse model of primary open-angle glaucoma.

Tseng H.C., Riday T.T., McKee C., Braine C.E., Bomze H., Barak I., Marean-Reardon C., John S.W., Philpot B.D., Ehlers M.D.

Neurobiol. Aging 36:2201-2212(2015) · Mapped (1)

VEGF receptor signaling links inflammation and tumorigenesis in colitis-associated cancer.

Waldner M.J., Wirtz S., Jefremow A., Warntjen M., Neufert C., Atreya R., Becker C., Weigmann B., Vieth M., Rose-John S. et al.

J. Exp. Med. 207:2855-2868(2010) · Mapped (45)

Variations in COL15A1 and COL18A1 influence age of onset of primary open angle glaucoma.

Wiggs J.L., Howell G.R., Linkroum K., Abdrabou W., Hodges E., Braine C.E., Pasquale L.R., Hannon G.J., Haines J.L., John S.W.

Clin. Genet. 84:167-174(2013) · Mapped (7)

Ureaplasma urealyticum meningitis in an adult patient.

Geissdorfer W., Sandner G., John S., Gessner A., Schoerner C., Schroppel K.

J. Clin. Microbiol. 46:1141-1143(2008) · UniProtKB (3)

Up- and down-regulation of granulocyte/macrophage-colony stimulating factor activity in murine skin increase susceptibility to skin carcinogenesis by independent mechanisms.

Mann A., Breuhahn K., Schirmacher P., Wilhelmi A., Beyer C., Rosenau A., Ozbek S., Rose-John S., Blessing M.

Cancer Res. 61:2311-2319(2001) · Mapped (3)

Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription.

Stavreva D.A., Wiench M., John S., Conway-Campbell B.L., McKenna M.A., Pooley J.R., Johnson T.A., Voss T.C., Lightman S.L., Hager G.L.

Nat. Cell Biol. 11:1093-1102(2009) · Mapped (13)

Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2.

Annibaldi A., Wicky John S., Vanden Berghe T., Swatek K.N., Ruan J., Liccardi G., Bianchi K., Elliott P.R., Choi S.M., Van Coillie S. et al.

Mol. Cell 69:566-580.e5(2018) · Mapped (12)

Two novel biallelic polymorphisms in the IL-2 gene.

John S., Turner D., Donn R., Sinnott P., Worthington J., Ollier W.E., Hutchinson I.V., Hajeer A.H.

Eur. J. Immunogenet. 25:419-420(1998) · UniProtKB (1)

Tumour necrosis factor-alpha single nucleotide polymorphisms are not independent of HLA class I in UK Caucasians with adult onset idiopathic inflammatory myopathies.

Chinoy H., Salway F., John S., Fertig N., Tait B.D., Oddis C.V., Ollier W.E., Cooper R.G.

Rheumatology (Oxford) 46:1411-1416(2007) · Mapped (1,481)

Tumor necrosis factor regulates intestinal epithelial cell migration by receptor-dependent mechanisms.

Corredor J., Yan F., Shen C.C., Tong W., John S.K., Wilson G., Whitehead R., Polk D.B.

Am. J. Physiol., Cell Physiol. 284:C953-61(2003) · Mapped (13)

Tumor necrosis factor inhibits ligand-stimulated EGF receptor activation through a TNF receptor 1-dependent mechanism.

McElroy S.J., Frey M.R., Yan F., Edelblum K.L., Goettel J.A., John S., Polk D.B.

Am. J. Physiol. Gastrointest. Liver Physiol. 295:G285-93(2008) · Mapped (9)

Tumor development in murine ulcerative colitis depends on MyD88 signaling of colonic F4/80+CD11b(high)Gr1(low) macrophages.

Schiechl G., Bauer B., Fuss I., Lang S.A., Moser C., Ruemmele P., Rose-John S., Neurath M.F., Geissler E.K., Schlitt H.J. et al.

J. Clin. Invest. 121:1692-1708(2011) · Mapped (24)

Trp53 deficiency protects against acute intestinal inflammation.

Spehlmann M.E., Manthey C.F., Dann S.M., Hanson E., Sandhu S.S., Liu L.Y., Abdelmalak F.K., Diamanti M.A., Retzlaff K., Scheller J. et al.

J. Immunol. 191:837-847(2013) · Mapped (54)

Transsignaling of interleukin-6 crucially contributes to atherosclerosis in mice.

Schuett H., Oestreich R., Waetzig G.H., Annema W., Luchtefeld M., Hillmer A., Bavendiek U., von Felden J., Divchev D., Kempf T. et al.

Arterioscler. Thromb. Vasc. Biol. 32:281-290(2012) · Mapped (5)

Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cells.

Heink S., Yogev N., Garbers C., Herwerth M., Aly L., Gasperi C., Husterer V., Croxford A.L., Moller-Hackbarth K., Bartsch H.S. et al.

Nat. Immunol. 18:74-85(2017) · Mapped (30)

Translational mini-review series on Th17 cells: induction of interleukin-17 production by regulatory T cells.

Afzali B., Mitchell P., Lechler R.I., John S., Lombardi G.

Clin. Exp. Immunol. 159:120-130(2010) · Mapped (4)

Transgenic mice overexpressing nNOS in the adult nervous system.

Packer M.A., Hemish J., Mignone J.L., John S., Pugach I., Enikolopov G.

Cell. Mol. Biol. (Noisy-le-grand) 51:269-277(2005) · Mapped (4)

Transgenic blockade of interleukin 6 transsignaling abrogates inflammation.

Rabe B., Chalaris A., May U., Waetzig G.H., Seegert D., Williams A.S., Jones S.A., Rose-John S., Scheller J.

Blood 111:1021-1028(2008) · Mapped (7)

Transcriptional profiling identifies Id2 function in dendritic cell development.

Hacker C., Kirsch R.D., Ju X.S., Hieronymus T., Gust T.C., Kuhl C., Jorgas T., Kurz S.M., Rose-John S., Yokota Y. et al.

Nat. Immunol. 4:380-386(2003) · Mapped (6)

Transcription factor NFATc2 controls the emergence of colon cancer associated with IL-6-dependent colitis.

Gerlach K., Daniel C., Lehr H.A., Nikolaev A., Gerlach T., Atreya R., Rose-John S., Neurath M.F., Weigmann B.

Cancer Res. 72:4340-4350(2012) · Mapped (17)

Transcription factor Ets1, but not the closely related factor Ets2, inhibits antibody-secreting cell differentiation.

John S., Russell L., Chin S.S., Luo W., Oshima R., Garrett-Sinha L.A.

Mol. Cell. Biol. 34:522-532(2014) · Mapped (18)

TNF-857T, a genetic risk marker for acute anterior uveitis.

Kuo N.W., Lympany P.A., Menezo V., Lagan A.L., John S., Yeo T.K., Liyanage S., du Bois R.M., Welsh K.I., Lightman S.

Invest. Ophthalmol. Vis. Sci. 46:1565-1571(2005) · Mapped (42)

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