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Literature citations Results

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Tyk2 mutation homologous to V617F Jak2 is not found in essential thrombocythaemia, although it induces constitutive signaling and growth factor independence.

Shide K., Shimoda K., Kamezaki K., Kakumitsu H., Kumano T., Numata A., Ishikawa F., Takenaka K., Yamamoto K., Matsuda T. et al.

Leuk. Res. 31:1077-1084(2007) · Mapped (4)

Toll-like receptor-4 is upregulated in plaque debris of patients with acute coronary syndrome more than Toll-like receptor-2.

Satoh S., Yada R., Inoue H., Omura S., Ejima E., Mori T., Takenaka K., Kawamura N., Numaguchi K., Mori E. et al.

Heart Vessels 31:1-5(2016) · Mapped (12)

Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells.

Ogi T., Limsirichaikul S., Overmeer R.M., Volker M., Takenaka K., Cloney R., Nakazawa Y., Niimi A., Miki Y., Jaspers N.G. et al.

Mol. Cell 37:714-727(2010) · UniProtKB (6) · Mapped (64)

The simultaneous inhibition of the mTOR and MAPK pathways with Gnetin-C induces apoptosis in acute myeloid leukemia.

Espinoza J.L., Elbadry M.I., Taniwaki M., Harada K., Trung L.Q., Nakagawa N., Takami A., Ishiyama K., Yamauchi T., Takenaka K. et al.

Cancer Lett. 400:127-136(2017) · Mapped (5)

The ratio of membrane-bound form Flt-1 mRNA to VEGF mRNA correlates with tumor angiogenesis and prognosis in non-small cell lung cancer.

Takenaka K., Katakura H., Chen F., Ogawa E., Adachi M., Wada H., Tanaka F.

Cancer Lett. 246:34-40(2007) · Mapped (28)

The ordered acquisition of Class II and Class I mutations directs formation of human t(8;21) acute myelogenous leukemia stem cell.

Shima T., Miyamoto T., Kikushige Y., Yuda J., Tochigi T., Yoshimoto G., Kato K., Takenaka K., Iwasaki H., Mizuno S. et al.

Exp. Hematol. 42:955-65.e1-5(2014) · Mapped (37)

The combination of HLA-B*15:01 and DRB1*15:01 is associated with gemcitabine plus erlotinib-induced interstitial lung disease in patients with advanced pancreatic cancer.

Nishimura M., Toyoda M., Takenaka K., Imamura Y., Chayahara N., Kiyota N., Mukohara T., Kotake T., Tsuji A., Saito K. et al.

Cancer Chemother. Pharmacol. 77:1165-1170(2016) · Mapped (7,272)

The BALB/c-specific polymorphic SIRPA enhances its affinity for human CD47, inhibiting phagocytosis against human cells to promote xenogeneic engraftment.

Iwamoto C., Takenaka K., Urata S., Yamauchi T., Shima T., Kuriyama T., Daitoku S., Saito Y., Miyamoto T., Iwasaki H. et al.

Exp. Hematol. 42:163-171.e1(2014) · Mapped (5)

The ABCC4 membrane transporter modulates platelet aggregation.

Cheepala S.B., Pitre A., Fukuda Y., Takenaka K., Zhang Y., Wang Y., Frase S., Pestina T., Gartner T.K., Jackson C. et al.

Blood 126:2307-2319(2015) · Mapped (14)

Telmisartan inhibits expression of a receptor for advanced glycation end products (RAGE) in angiotensin-II-exposed endothelial cells and decreases serum levels of soluble RAGE in patients with essential hypertension.

Nakamura K., Yamagishi S., Nakamura Y., Takenaka K., Matsui T., Jinnouchi Y., Imaizumi T.

Microvasc. Res. 70:137-141(2005) · Mapped (39)

Substrate overlap between Mrp4 and Abcg2/Bcrp affects purine analogue drug cytotoxicity and tissue distribution.

Takenaka K., Morgan J.A., Scheffer G.L., Adachi M., Stewart C.F., Sun D., Leggas M., Ejendal K.F., Hrycyna C.A., Schuetz J.D.

Cancer Res. 67:6965-6972(2007) · Mapped (17)

Stromal aminopeptidase N expression: correlation with angiogenesis in non-small-cell lung cancer.

Ito S., Miyahara R., Takahashi R., Nagai S., Takenaka K., Wada H., Tanaka F.

Gen Thorac Cardiovasc Surg 57:591-598(2009) · Mapped (9)

Somatic mutation of the Caspase-5 gene in human lung cancer.

Hosomi Y., Gemma A., Hosoya Y., Nara M., Okano T., Takenaka K., Yoshimura A., Koizumi K., Shimizu K., Kudoh S.

Int. J. Mol. Med. 12:443-446(2003) · Mapped (3)

Search on chromosome 17 centromere reveals TNFRSF13B as a susceptibility gene for intracranial aneurysm: a preliminary study.

Inoue K., Mineharu Y., Inoue S., Yamada S., Matsuda F., Nozaki K., Takenaka K., Hashimoto N., Koizumi A.

Circulation 113:2002-2010(2006) · Mapped (4)

Role of phospholipase C-L2, a novel phospholipase C-like protein that lacks lipase activity, in B-cell receptor signaling.

Takenaka K., Fukami K., Otsuki M., Nakamura Y., Kataoka Y., Wada M., Tsuji K., Nishikawa S., Yoshida N., Takenawa T.

Mol. Cell. Biol. 23:7329-7338(2003) · Mapped (1)

Reduced transcription of the RB2/p130 gene in human lung cancer.

Xue Jun H., Gemma A., Hosoya Y., Matsuda K., Nara M., Hosomi Y., Okano T., Kurimoto F., Seike M., Takenaka K. et al.

Mol. Carcinog. 38:124-129(2003) · Mapped (3)

Purification, identification, and characterization of two GTP-binding proteins with molecular weights of 25,000 and 21,000 in human platelet cytosol. One is the rap1/smg21/Krev-1 protein and the other is a novel GTP-binding protein.

Nagata K., Itoh H., Katada T., Takenaka K., Ui M., Kaziro Y., Nozawa Y.

J. Biol. Chem. 264:17000-17005(1989) · UniProtKB (2)

PTIP promotes DNA double-strand break repair through homologous recombination.

Wang X., Takenaka K., Takeda S.

Genes Cells 15:243-254(2010) · UniProtKB (1) · Mapped (2)

Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells.

Takenaka K., Prasolava T.K., Wang J.C., Mortin-Toth S.M., Khalouei S., Gan O.I., Dick J.E., Danska J.S.

Nat. Immunol. 8:1313-1323(2007) · Mapped (28)

Polymorphic Sirpa is the genetic determinant for NOD-based mouse lines to achieve efficient human cell engraftment.

Yamauchi T., Takenaka K., Urata S., Shima T., Kikushige Y., Tokuyama T., Iwamoto C., Nishihara M., Iwasaki H., Miyamoto T. et al.

Blood 121:1316-1325(2013) · Mapped (17)

Pigment epithelium-derived factor inhibits neointimal hyperplasia after vascular injury by blocking NADPH oxidase-mediated reactive oxygen species generation.

Nakamura K., Yamagishi S., Matsui T., Yoshida T., Takenaka K., Jinnouchi Y., Yoshida Y., Ueda S., Adachi H., Imaizumi T.

Am. J. Pathol. 170:2159-2170(2007) · Mapped (2)

Pigment epithelium-derived factor inhibits advanced glycation end product-induced retinal vascular hyperpermeability by blocking reactive oxygen species-mediated vascular endothelial growth factor expression.

Yamagishi S., Nakamura K., Matsui T., Inagaki Y., Takenaka K., Jinnouchi Y., Yoshida Y., Matsuura T., Narama I., Motomiya Y. et al.

J. Biol. Chem. 281:20213-20220(2006) · Mapped (13)

Phospholipase C-related inactive protein is involved in trafficking of gamma2 subunit-containing GABA(A) receptors to the cell surface.

Mizokami A., Kanematsu T., Ishibashi H., Yamaguchi T., Tanida I., Takenaka K., Nakayama K.I., Fukami K., Takenawa T., Kominami E. et al.

J. Neurosci. 27:1692-1701(2007) · UniProtKB (1) · Mapped (1)

Phospholipase Cdelta4: from genome structure to physiological function.

Fukami K., Inoue T., Kurokawa M., Fissore R.A., Nakao K., Nagano K., Nakamura Y., Takenaka K., Yoshida N., Mikoshiba K. et al.

Adv. Enzyme Regul. 43:87-106(2003) · Mapped (2)

Phospholipase Cdelta1 is required for skin stem cell lineage commitment.

Nakamura Y., Fukami K., Yu H., Takenaka K., Kataoka Y., Shirakata Y., Nishikawa S., Hashimoto K., Yoshida N., Takenawa T.

EMBO J. 22:2981-2991(2003) · Mapped (3)

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