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Entry version 59 (13 Nov 2019)
Sequence version 1 (09 Jul 2014)
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Protein

Protein/nucleic acid deglycase HchA

Gene

hchA

Organism
Escherichia coli
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal-and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of Schiff bases and advanced glycation endproducts (AGE). Also functions as a nucleotide deglycase able to repair glycated guanine in the free nucleotide pool (GTP, GDP, GMP, dGTP) and in DNA and RNA. Is thus involved in a major nucleotide repair system named guanine glycation repair (GG repair), dedicated to reversing methylglyoxal and glyoxal damage via nucleotide sanitization and direct nucleic acid repair. Plays an important role in protecting cells from carbonyl stress.UniRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi86ZincUniRule annotation1
Metal bindingi91ZincUniRule annotation1
Metal bindingi123ZincUniRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei185NucleophileUniRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolaseUniRule annotationImported, LyaseImported
Biological processDNA damage, DNA repairUniRule annotation, Stress responseUniRule annotationImported
LigandMetal-bindingUniRule annotation, ZincUniRule annotation

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
GCF_001562855-HMP:HMPREF3040_RS07535-MONOMER
GCF_001936315:BJJ90_RS16335-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein/nucleic acid deglycase HchAUniRule annotation (EC:3.1.2.-UniRule annotation, EC:3.5.1.-UniRule annotation, EC:3.5.1.124UniRule annotation)
Alternative name(s):
Maillard deglycaseUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:hchAUniRule annotationImported
ORF Names:A8C65_13880Imported, A9R57_25255Imported, AKG99_20940Imported, AMK83_16550Imported, B7C53_22525Imported, B9M99_11580Imported, B9T59_01945Imported, BJJ90_15205Imported, BMT49_12710Imported, BON66_15955Imported, BON86_06490Imported, BON95_14610Imported, BUE81_10670Imported, BvCms12BK_01457Imported, BvCms28BK_04168Imported, BvCmsHHP001_02632Imported, BvCmsKKP061_00566Imported, BvCmsKSP015_01352Imported, BvCmsKSP045_04450Imported, BvCmsKSP058_03204Imported, BvCmsKSP067_02879Imported, BvCmsKSP083_03900Imported, BvCmsNSP006_03750Imported, BvCmsNSP007_03329Imported, BvCmsNSP047_03567Imported, BvCmsSINP011_04162Imported, BW690_17225Imported, BZL69_29425Imported, C2U48_24800Imported, C5715_19445Imported, C5N07_21380Imported, C6669_19295Imported, C7B06_02290Imported, C7B07_03930Imported, C9025_17620Imported, C9083_21590Imported, C9212_13125Imported, C9Y80_10480Imported, C9Y95_17520Imported, C9Z12_18550Imported, CDL37_00765Imported, CEG98_15470Imported, CI694_25210Imported, CIJ94_05515Imported, COD46_23180Imported, CQP61_17160Imported, CRD98_26150Imported, CY655_12940Imported, D2188_01360Imported, D6W60_25270Imported, D9D20_21030Imported, D9D43_06110Imported, D9H68_20750Imported, D9H70_25730Imported, D9I87_15275Imported, DEN89_24995Imported, DEO11_07425Imported, DL800_09215Imported, DNQ41_14245Imported, DQE83_22775Imported, DTL43_21780Imported, DTM25_06080Imported, DU321_04440Imported, DXT73_20690Imported, E2134_24005Imported, E2135_17195Imported, E2855_02503Imported, E2863_02392Imported, E5P22_21380Imported, E5S46_06650Imported, EB575_25290Imported, EC95NR1_00961Imported, ED648_25045Imported, ELT20_21515Imported, ELV08_24970Imported, EPS97_16570Imported, EPT01_11070Imported, EQ825_23250Imported, ERS085379_01273Imported, ERS085386_05041Imported, ExPECSC038_01920Imported, EXX71_02385Imported, EXX78_21815Imported, EYD11_09165Imported, FNJ83_13175Imported, FQ915_04255Imported, FQR64_09390Imported, FWK02_18105Imported, HmCmsJML079_02678Imported, HMPREF3040_01583Imported, HW43_13705Imported, NCTC10082_04431Imported, NCTC10418_03071Imported, NCTC10767_03558Imported, NCTC11022_01867Imported, NCTC11126_04427Imported, NCTC11181_05650Imported, NCTC12950_02263Imported, NCTC13462_05714Imported, NCTC8985_00529Imported, NCTC9111_05933Imported, NCTC9703_00277Imported, PGD_01271Imported, PU06_24500Imported, SAMEA3472043_00447Imported, SAMEA3472055_03589Imported, SAMEA3472056_01268Imported, SAMEA3472070_00654Imported, SAMEA3472080_04213Imported, SAMEA3472090_03376Imported, SAMEA3472110_00060Imported, SAMEA3472112_00448Imported, SAMEA3752372_00752Imported, UN91_23615Imported, WQ89_10695Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coliImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri562 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By heat shock.UniRule annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

UniRule annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the peptidase C56 family. HchA subfamily.UniRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG0693 LUCA

Database of Orthologous Groups

More...
OrthoDBi
1152952at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
3.40.50.880, 1 hit

HAMAP database of protein families

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HAMAPi
MF_01046 Deglycase_HchA, 1 hit

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR029062 Class_I_gatase-like
IPR017283 HchA

The PANTHER Classification System

More...
PANTHERi
PTHR43824:SF8 PTHR43824:SF8, 1 hit

PIRSF; a whole-protein classification database

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PIRSFi
PIRSF037798 Chaperone_HchA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52317 SSF52317, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A024L2A9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTVQTSKNPQ VDIAEDNAFF PSEYSLSQYT SPVSDLDGVD YPKPYRGKHK
60 70 80 90 100
ILVIAADERY LPTDNGKLFS TGNHPIETLL PLYHLHAAGF EFEVATISGL
110 120 130 140 150
MTKFEYWAMP HKDEKVMPFF EQHKSLFRNP KKLADVVASL NADSEYAAIF
160 170 180 190 200
VPGGHGALIG LPESQDVAAA LQWAIKNDRF VISLCHGPAA FLALRHGDNP
210 220 230 240 250
LNGYSICAFP DAADKQTPEI GYMPGHLTWY FGEELKKMGM NIINDDITGR
260 270 280
VHKDRKVLTG DSPFAANALG KLAAQEMLAA YAG
Length:283
Mass (Da):31,176
Last modified:July 9, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5CA8BE99F9A83B72
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP009106 Genomic DNA Translation: AIZ87477.1
CP017631 Genomic DNA Translation: APT03265.1
CP021339 Genomic DNA Translation: ART24836.1
CP026202 Genomic DNA Translation: AUV33619.1
CP021193 Genomic DNA Translation: AWR80034.1
CP029692 Genomic DNA Translation: AWS36017.1
CP029973 Genomic DNA Translation: AWV11365.1
CP031134 Genomic DNA Translation: AXG18990.1
CP033635 Genomic DNA Translation: AYW31046.1
CP025573 Genomic DNA Translation: AZZ26909.1
AP018796 Genomic DNA Translation: BBF48096.1
AP018802 Genomic DNA Translation: BBF53883.1
CCCP010000012 Genomic DNA Translation: CDP71004.1
HG976952 Genomic DNA Translation: CDU38195.1
CYBF01000007 Genomic DNA Translation: CTT47607.1
CYBM01000058 Genomic DNA Translation: CTU20430.1
BHZO01000014 Genomic DNA Translation: GCF99761.1
BIAF01000092 Genomic DNA Translation: GCH08557.1
BFIH01000036 Genomic DNA Translation: GCO24801.1
BFKI01000100 Genomic DNA Translation: GCR80410.1
BFOT01000078 Genomic DNA Translation: GCY57647.1
BFXY01000023 Genomic DNA Translation: GDH29133.1
BGBC01000113 Genomic DNA Translation: GDL45803.1
BFZZ01000016 Genomic DNA Translation: GDL47944.1
BGAV01000094 Genomic DNA Translation: GDL76575.1
BGBP01000034 Genomic DNA Translation: GDM74344.1
BGBI01000048 Genomic DNA Translation: GDO47595.1
BGDM01000152 Genomic DNA Translation: GDP37344.1
BGDN01000132 Genomic DNA Translation: GDP81692.1
BGEG01000088 Genomic DNA Translation: GDR52300.1
BGGV01000143 Genomic DNA Translation: GDR90575.1
JUDN01000149 Genomic DNA Translation: KHJ14403.1
JZDZ01000109 Genomic DNA Translation: KJW45163.1
LGZP01000018 Genomic DNA Translation: KNF80390.1
LHAT01000065 Genomic DNA Translation: KNZ97201.1
LSNZ01000057 Genomic DNA Translation: KXH00674.1
LOCS01000142 Genomic DNA Translation: KYV68606.1
RLHY01000068 Genomic DNA Translation: MDT69877.1
RMML01000121 Genomic DNA Translation: MFA55141.1
RNLT01000033 Genomic DNA Translation: MGD92361.1
RNLZ01000007 Genomic DNA Translation: MGE13169.1
RNTP01000094 Genomic DNA Translation: MHP18178.1
ROBI01000028 Genomic DNA Translation: MIA49483.1
RNVW01000057 Genomic DNA Translation: MIC26275.1
RVRO01000091 Genomic DNA Translation: MMG62431.1
LZEH01000037 Genomic DNA Translation: OEI66394.1
MPGQ01000001 Genomic DNA Translation: OKB79100.1
MSEK01000069 Genomic DNA Translation: OLR87354.1
MTKH01000136 Genomic DNA Translation: ONG27328.1
MUBQ01000090 Genomic DNA Translation: OUK85779.1
LYBG01000719 Genomic DNA Translation: OWD69214.1
NBSF01000064 Genomic DNA Translation: OWS83388.1
NIIS01000001 Genomic DNA Translation: OXK54204.1
NQBT01000212 Genomic DNA Translation: OYI43930.1
NQIT01000010 Genomic DNA Translation: OZX97297.1
NIYQ01000105 Genomic DNA Translation: PAY72463.1
NWAO01000049 Genomic DNA Translation: PBR50046.1
PUJR01000029 Genomic DNA Translation: PQP07737.1
PUQC01000146 Genomic DNA Translation: PQP29065.1
PYQW01000002 Genomic DNA Translation: PSY81747.1
PYQV01000002 Genomic DNA Translation: PSZ22501.1
CP036177 Genomic DNA Translation: QBF91063.1
CP041522 Genomic DNA Translation: QDM70954.1
CP042585 Genomic DNA Translation: QED51980.1
QMKN01000025 Genomic DNA Translation: RAX32904.1
NFTV01000011 Genomic DNA Translation: RBV92817.1
QOGR01000004 Genomic DNA Translation: RCZ87495.1
QOGZ01000035 Genomic DNA Translation: RDA34553.1
PDAN01000080 Genomic DNA Translation: RFQ64179.1
QYZG01000001 Genomic DNA Translation: RJF05114.1
RRVG01000003 Genomic DNA Translation: RRL50198.1
SCGK01000032 Genomic DNA Translation: RXA48232.1
SCIU01000034 Genomic DNA Translation: RXB27573.1
SCIR01000016 Genomic DNA Translation: RXB67488.1
SHHG01000031 Genomic DNA Translation: RZW26812.1
SHHN01000002 Genomic DNA Translation: RZW72873.1
UARS01000009 Genomic DNA Translation: SPW54775.1
UARY01000011 Genomic DNA Translation: SPW89715.1
UASF01000009 Genomic DNA Translation: SQD00206.1
UCTW01000001 Genomic DNA Translation: SQJ50208.1
UCVA01000004 Genomic DNA Translation: SQK82585.1
UCVG01000001 Genomic DNA Translation: SQL08281.1
UCVC01000027 Genomic DNA Translation: SQL29476.1
UCXQ01000003 Genomic DNA Translation: SQO10558.1
UEJU01000013 Genomic DNA Translation: SRY23915.1
UFXW01000004 Genomic DNA Translation: STC85269.1
UFZA01000002 Genomic DNA Translation: STE71544.1
UFYN01000009 Genomic DNA Translation: STE77685.1
UFZQ01000001 Genomic DNA Translation: STE85461.1
UGCG01000003 Genomic DNA Translation: STI33514.1
UGCO01000001 Genomic DNA Translation: STI75309.1
UGEA01000005 Genomic DNA Translation: STK48850.1
UGFM01000001 Genomic DNA Translation: STP46021.1
UINN01000001 Genomic DNA Translation: SVF07432.1
UINH01000002 Genomic DNA Translation: SVF08682.1
UINI01000033 Genomic DNA Translation: SVF36439.1
SNTV01000044 Genomic DNA Translation: TEV05223.1
SNTW01000044 Genomic DNA Translation: TEV31560.1
MTWZ01000073 Genomic DNA Translation: TEZ16852.1
MTXT01000020 Genomic DNA Translation: TFA19111.1
MTYC01000035 Genomic DNA Translation: TFA65399.1
RZDD01000126 Genomic DNA Translation: TFP29980.1
RZBT01000047 Genomic DNA Translation: TFR24959.1
QERS01000005 Genomic DNA Translation: TFX33631.1
QESO01000031 Genomic DNA Translation: TFY28177.1
QRFM01000032 Genomic DNA Translation: TGD62953.1
SRMS01000004 Genomic DNA Translation: TGI08689.1
SROW01000161 Genomic DNA Translation: TGJ55810.1
RRPF01000020 Genomic DNA Translation: TJE76204.1
RRKL01000040 Genomic DNA Translation: TJK89817.1
RRIG01000029 Genomic DNA Translation: TJN70511.1
RREH01000027 Genomic DNA Translation: TJS94158.1
RRDQ01000027 Genomic DNA Translation: TJT61912.1
RRDB01000012 Genomic DNA Translation: TJU31619.1
VODA01000022 Genomic DNA Translation: TWP67668.1
VSBS01000682 Genomic DNA Translation: TXT00347.1

NCBI Reference Sequences

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RefSeqi
WP_000218214.1, NZ_VRXZ01000001.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

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EnsemblBacteriai
AIZ82988; AIZ82988; HW42_14095
CDU38195; CDU38195; PGD_01271
CTT47607; CTT47607; ERS085379_01273
CTU20430; CTU20430; ERS085386_05041
KHI36969; KHI36969; PU33_03400
KHJ14403; KHJ14403; PU06_24500
KIG81291; KIG81291; PU38_10665
KIH05836; KIH05836; PU21_11425
KJW45163; KJW45163; UN91_23615
KNF80390; KNF80390; WQ89_10695
KNY74737; KNY74737; AGA26_15580
KNZ97201; KNZ97201; AKG99_20940
KUU39458; KUU39458; AWF22_11735
KXH00674; KXH00674; HMPREF3040_01583
KYV68606; KYV68606; AMK83_16550
KZJ57871; KZJ57871; AWG90_01520
OAJ88961; OAJ88961; A5958_20780
OAS82335; OAS82335; A6I92_11550
OCO44190; OCO44190; AN669_0219065
ODH27375; ODH27375; A6803_21690
OEI66394; OEI66394; A9R57_25255

Pathosystems Resource Integration Center (PATRIC)

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PATRICi
fig|562.10472.peg.1936

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009106 Genomic DNA Translation: AIZ87477.1
CP017631 Genomic DNA Translation: APT03265.1
CP021339 Genomic DNA Translation: ART24836.1
CP026202 Genomic DNA Translation: AUV33619.1
CP021193 Genomic DNA Translation: AWR80034.1
CP029692 Genomic DNA Translation: AWS36017.1
CP029973 Genomic DNA Translation: AWV11365.1
CP031134 Genomic DNA Translation: AXG18990.1
CP033635 Genomic DNA Translation: AYW31046.1
CP025573 Genomic DNA Translation: AZZ26909.1
AP018796 Genomic DNA Translation: BBF48096.1
AP018802 Genomic DNA Translation: BBF53883.1
CCCP010000012 Genomic DNA Translation: CDP71004.1
HG976952 Genomic DNA Translation: CDU38195.1
CYBF01000007 Genomic DNA Translation: CTT47607.1
CYBM01000058 Genomic DNA Translation: CTU20430.1
BHZO01000014 Genomic DNA Translation: GCF99761.1
BIAF01000092 Genomic DNA Translation: GCH08557.1
BFIH01000036 Genomic DNA Translation: GCO24801.1
BFKI01000100 Genomic DNA Translation: GCR80410.1
BFOT01000078 Genomic DNA Translation: GCY57647.1
BFXY01000023 Genomic DNA Translation: GDH29133.1
BGBC01000113 Genomic DNA Translation: GDL45803.1
BFZZ01000016 Genomic DNA Translation: GDL47944.1
BGAV01000094 Genomic DNA Translation: GDL76575.1
BGBP01000034 Genomic DNA Translation: GDM74344.1
BGBI01000048 Genomic DNA Translation: GDO47595.1
BGDM01000152 Genomic DNA Translation: GDP37344.1
BGDN01000132 Genomic DNA Translation: GDP81692.1
BGEG01000088 Genomic DNA Translation: GDR52300.1
BGGV01000143 Genomic DNA Translation: GDR90575.1
JUDN01000149 Genomic DNA Translation: KHJ14403.1
JZDZ01000109 Genomic DNA Translation: KJW45163.1
LGZP01000018 Genomic DNA Translation: KNF80390.1
LHAT01000065 Genomic DNA Translation: KNZ97201.1
LSNZ01000057 Genomic DNA Translation: KXH00674.1
LOCS01000142 Genomic DNA Translation: KYV68606.1
RLHY01000068 Genomic DNA Translation: MDT69877.1
RMML01000121 Genomic DNA Translation: MFA55141.1
RNLT01000033 Genomic DNA Translation: MGD92361.1
RNLZ01000007 Genomic DNA Translation: MGE13169.1
RNTP01000094 Genomic DNA Translation: MHP18178.1
ROBI01000028 Genomic DNA Translation: MIA49483.1
RNVW01000057 Genomic DNA Translation: MIC26275.1
RVRO01000091 Genomic DNA Translation: MMG62431.1
LZEH01000037 Genomic DNA Translation: OEI66394.1
MPGQ01000001 Genomic DNA Translation: OKB79100.1
MSEK01000069 Genomic DNA Translation: OLR87354.1
MTKH01000136 Genomic DNA Translation: ONG27328.1
MUBQ01000090 Genomic DNA Translation: OUK85779.1
LYBG01000719 Genomic DNA Translation: OWD69214.1
NBSF01000064 Genomic DNA Translation: OWS83388.1
NIIS01000001 Genomic DNA Translation: OXK54204.1
NQBT01000212 Genomic DNA Translation: OYI43930.1
NQIT01000010 Genomic DNA Translation: OZX97297.1
NIYQ01000105 Genomic DNA Translation: PAY72463.1
NWAO01000049 Genomic DNA Translation: PBR50046.1
PUJR01000029 Genomic DNA Translation: PQP07737.1
PUQC01000146 Genomic DNA Translation: PQP29065.1
PYQW01000002 Genomic DNA Translation: PSY81747.1
PYQV01000002 Genomic DNA Translation: PSZ22501.1
CP036177 Genomic DNA Translation: QBF91063.1
CP041522 Genomic DNA Translation: QDM70954.1
CP042585 Genomic DNA Translation: QED51980.1
QMKN01000025 Genomic DNA Translation: RAX32904.1
NFTV01000011 Genomic DNA Translation: RBV92817.1
QOGR01000004 Genomic DNA Translation: RCZ87495.1
QOGZ01000035 Genomic DNA Translation: RDA34553.1
PDAN01000080 Genomic DNA Translation: RFQ64179.1
QYZG01000001 Genomic DNA Translation: RJF05114.1
RRVG01000003 Genomic DNA Translation: RRL50198.1
SCGK01000032 Genomic DNA Translation: RXA48232.1
SCIU01000034 Genomic DNA Translation: RXB27573.1
SCIR01000016 Genomic DNA Translation: RXB67488.1
SHHG01000031 Genomic DNA Translation: RZW26812.1
SHHN01000002 Genomic DNA Translation: RZW72873.1
UARS01000009 Genomic DNA Translation: SPW54775.1
UARY01000011 Genomic DNA Translation: SPW89715.1
UASF01000009 Genomic DNA Translation: SQD00206.1
UCTW01000001 Genomic DNA Translation: SQJ50208.1
UCVA01000004 Genomic DNA Translation: SQK82585.1
UCVG01000001 Genomic DNA Translation: SQL08281.1
UCVC01000027 Genomic DNA Translation: SQL29476.1
UCXQ01000003 Genomic DNA Translation: SQO10558.1
UEJU01000013 Genomic DNA Translation: SRY23915.1
UFXW01000004 Genomic DNA Translation: STC85269.1
UFZA01000002 Genomic DNA Translation: STE71544.1
UFYN01000009 Genomic DNA Translation: STE77685.1
UFZQ01000001 Genomic DNA Translation: STE85461.1
UGCG01000003 Genomic DNA Translation: STI33514.1
UGCO01000001 Genomic DNA Translation: STI75309.1
UGEA01000005 Genomic DNA Translation: STK48850.1
UGFM01000001 Genomic DNA Translation: STP46021.1
UINN01000001 Genomic DNA Translation: SVF07432.1
UINH01000002 Genomic DNA Translation: SVF08682.1
UINI01000033 Genomic DNA Translation: SVF36439.1
SNTV01000044 Genomic DNA Translation: TEV05223.1
SNTW01000044 Genomic DNA Translation: TEV31560.1
MTWZ01000073 Genomic DNA Translation: TEZ16852.1
MTXT01000020 Genomic DNA Translation: TFA19111.1
MTYC01000035 Genomic DNA Translation: TFA65399.1
RZDD01000126 Genomic DNA Translation: TFP29980.1
RZBT01000047 Genomic DNA Translation: TFR24959.1
QERS01000005 Genomic DNA Translation: TFX33631.1
QESO01000031 Genomic DNA Translation: TFY28177.1
QRFM01000032 Genomic DNA Translation: TGD62953.1
SRMS01000004 Genomic DNA Translation: TGI08689.1
SROW01000161 Genomic DNA Translation: TGJ55810.1
RRPF01000020 Genomic DNA Translation: TJE76204.1
RRKL01000040 Genomic DNA Translation: TJK89817.1
RRIG01000029 Genomic DNA Translation: TJN70511.1
RREH01000027 Genomic DNA Translation: TJS94158.1
RRDQ01000027 Genomic DNA Translation: TJT61912.1
RRDB01000012 Genomic DNA Translation: TJU31619.1
VODA01000022 Genomic DNA Translation: TWP67668.1
VSBS01000682 Genomic DNA Translation: TXT00347.1
RefSeqiWP_000218214.1, NZ_VRXZ01000001.1

3D structure databases

Database of comparative protein structure models

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ModBasei
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
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Genome annotation databases

EnsemblBacteriaiAIZ82988; AIZ82988; HW42_14095
CDU38195; CDU38195; PGD_01271
CTT47607; CTT47607; ERS085379_01273
CTU20430; CTU20430; ERS085386_05041
KHI36969; KHI36969; PU33_03400
KHJ14403; KHJ14403; PU06_24500
KIG81291; KIG81291; PU38_10665
KIH05836; KIH05836; PU21_11425
KJW45163; KJW45163; UN91_23615
KNF80390; KNF80390; WQ89_10695
KNY74737; KNY74737; AGA26_15580
KNZ97201; KNZ97201; AKG99_20940
KUU39458; KUU39458; AWF22_11735
KXH00674; KXH00674; HMPREF3040_01583
KYV68606; KYV68606; AMK83_16550
KZJ57871; KZJ57871; AWG90_01520
OAJ88961; OAJ88961; A5958_20780
OAS82335; OAS82335; A6I92_11550
OCO44190; OCO44190; AN669_0219065
ODH27375; ODH27375; A6803_21690
OEI66394; OEI66394; A9R57_25255
PATRICifig|562.10472.peg.1936

Phylogenomic databases

eggNOGiCOG0693 LUCA
OrthoDBi1152952at2

Enzyme and pathway databases

BioCyciGCF_001562855-HMP:HMPREF3040_RS07535-MONOMER
GCF_001936315:BJJ90_RS16335-MONOMER

Family and domain databases

Gene3Di3.40.50.880, 1 hit
HAMAPiMF_01046 Deglycase_HchA, 1 hit
InterProiView protein in InterPro
IPR029062 Class_I_gatase-like
IPR017283 HchA
PANTHERiPTHR43824:SF8 PTHR43824:SF8, 1 hit
PIRSFiPIRSF037798 Chaperone_HchA, 1 hit
SUPFAMiSSF52317 SSF52317, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A024L2A9_ECOLX
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A024L2A9
Secondary accession number(s): A0A236LSQ8, A0A2A2XKN4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: November 13, 2019
This is version 59 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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