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Entry version 17 (31 Jul 2019)
Sequence version 1 (03 Sep 2014)
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Protein
Submitted name:

Collagen alpha-1(III) chain-like isoform 2

Gene

H671_2g5666

Organism
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Collagen alpha-1(III) chain-like isoform 2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:H671_2g5666Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10029 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaCricetidaeCricetinaeCricetulus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000030759 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 27Sequence analysisAdd BLAST27
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500160097928 – 1470Sequence analysisAdd BLAST1443

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini35 – 94VWFCInterPro annotationAdd BLAST60
Domaini1236 – 1470Fibrillar collagen NC1InterPro annotationAdd BLAST235

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni101 – 1203DisorderedSequence analysisAdd BLAST1103

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi101 – 125Pro-richSequence analysisAdd BLAST25
Compositional biasi147 – 162PolarSequence analysisAdd BLAST16
Compositional biasi180 – 207Pro-richSequence analysisAdd BLAST28
Compositional biasi213 – 228Pro-richSequence analysisAdd BLAST16
Compositional biasi564 – 578Pro-richSequence analysisAdd BLAST15
Compositional biasi711 – 725Pro-richSequence analysisAdd BLAST15
Compositional biasi891 – 908Pro-richSequence analysisAdd BLAST18
Compositional biasi1186 – 1200Pro-richSequence analysisAdd BLAST15

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

CollagenImported, SignalSequence analysis

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008160 Collagen
IPR000885 Fib_collagen_C
IPR001007 VWF_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01410 COLFI, 1 hit
PF01391 Collagen, 5 hits
PF00093 VWC, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00038 COLFI, 1 hit
SM00214 VWC, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51461 NC1_FIB, 1 hit
PS01208 VWFC_1, 1 hit
PS50184 VWFC_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A061IIR5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAQDMMSFVQ SGTWLLLALL HPTFIWAQQS SVDESGCSHL GQSYESRDVW
60 70 80 90 100
KPEPCQICVC DSGSVLCDDI ICDEDPLDCP NPEIPFGECC AICPQPSTAA
110 120 130 140 150
PVPPDGHGPQ GPKGDPGPPG IPGRNGDPGL PGQPGLPGPP GSPGICESCP
160 170 180 190 200
TSGQNYSPQY DSYDVKSGVG AGGLGGGYPG PAGPPGPPGP PGSVGHPGSP
210 220 230 240 250
GSPGYQGPPG EPGQAGPSGP PGPPGAIGPS GPAGKDGESG RPGRPGERGL
260 270 280 290 300
PGPPGIKGPS GMPGFPGMKG HRGFDGRNGE KGETGAPGLK GENGLPGDNG
310 320 330 340 350
APGPMGPRGA PGERGRPGLP GAAGARGNDG ARGSDGQPGP PGPPGTAGFP
360 370 380 390 400
GSPGAKGEVG PAGSPGSNGS PGQRGEPGPQ GHAGAQGPPG PPGNNGSPGG
410 420 430 440 450
KGEMGPAGIP GAPGLMGARG PPGPAGTNGA PGQRGPSGEP GKNGAKGEPG
460 470 480 490 500
ARGERGEAGS PGIPGPKGED GKDGSPGEPG ANGLPGTAGE RGAPGFRGPA
510 520 530 540 550
GPNGIPGEKG PAGERGAPGP AGPRGVAGEP GRDGNPGGPG MRGVPGSPGG
560 570 580 590 600
PGNDGKPGPP GSQGESGRPG PPGPSGPRGQ PGVMGFPGPK GNDGAPGKNG
610 620 630 640 650
ERGGPGGPGL PGPAGKNGET GPQGPPGPTG PSGDKGESGP PGPQGLQGIP
660 670 680 690 700
GTSGPPGENG KPGEPGPKGE VGAPGVPGGK GDAGAPGERG PPGTAGAPGL
710 720 730 740 750
RGGAGPPGPE GGKGPAGPPG PPGTSGSPGL QGMPGERGGP GSPGPKGEKG
760 770 780 790 800
EPGGAGADGA PGKDGPRGPT GPIGPPGPAG QPGDKGEGGA PGLPGIAGPR
810 820 830 840 850
GGPGERGEHG PPGPAGFPGA PGQNGEPGAK GERGAPGEKG EGGPPGPAGL
860 870 880 890 900
PGGSGPAGPP GPQGVKGERG SPGGPGAAGF PGGRGLPGPP GNNGNPGPPG
910 920 930 940 950
PSGAPGKDGP PGPAGNSGSP GNPGVAGPKG DAGQPGEKGP PGAQGPPGSP
960 970 980 990 1000
GPLGIAGLTG ARGLAGPPGM PGPRGSPGPQ GIKGESGKPG ASGHNGERGP
1010 1020 1030 1040 1050
PGPQGLPGQP GTAGEPGRDG NPGSDGQPGR DGSPGGKGDR GENGSPGAPG
1060 1070 1080 1090 1100
APGHPGPPGP VGPAGKSGDR GETGPAGPSG APGPAGSRGP PGPQGPRGDK
1110 1120 1130 1140 1150
GETGERGSNG IKGHRGFPGN PGPPGSPGAA GHQGAVGSPG PAGPRGPVGP
1160 1170 1180 1190 1200
HGPPGKDGTS GHPGPIGPPG PRGNRGERGS EGSPGHPGQP GPPGPPGAPG
1210 1220 1230 1240 1250
PCCGGGAAAL GGGGEKSGGF SPYYGDEPMD FKINTEEIMS SLKSVNGQIE
1260 1270 1280 1290 1300
SLISPDGSRK NPARNCRDLK FCHPDLKSGE YWVDPNQGCK MDAIKVFCNM
1310 1320 1330 1340 1350
ETGETCINAS PMTVPRKNWW TDASAEKKHV WFGESMNGGF QFSYGNPDLP
1360 1370 1380 1390 1400
EDVLDVQLAY LRLLSSRASQ NITYHCKNSI AYMDQASGNV KKSLKLMGSN
1410 1420 1430 1440 1450
EGEFKAEGNS KFTYTVLEDG CAKHTGEWSK TVFEYRTRKA LRLPIIDIAP
1460 1470
YDIGGPDQEF GVDIGPVCFL
Length:1,470
Mass (Da):139,543
Last modified:September 3, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7EFF207ECBE4A063
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
KE667801 Genomic DNA Translation: ERE84830.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KE667801 Genomic DNA Translation: ERE84830.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

InterProiView protein in InterPro
IPR008160 Collagen
IPR000885 Fib_collagen_C
IPR001007 VWF_dom
PfamiView protein in Pfam
PF01410 COLFI, 1 hit
PF01391 Collagen, 5 hits
PF00093 VWC, 1 hit
SMARTiView protein in SMART
SM00038 COLFI, 1 hit
SM00214 VWC, 1 hit
PROSITEiView protein in PROSITE
PS51461 NC1_FIB, 1 hit
PS01208 VWFC_1, 1 hit
PS50184 VWFC_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A061IIR5_CRIGR
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A061IIR5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 3, 2014
Last sequence update: September 3, 2014
Last modified: July 31, 2019
This is version 17 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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