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Entry version 36 (16 Oct 2019)
Sequence version 1 (04 Mar 2015)
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Protein

RNA-directed RNA polymerase L

Gene

L

Organism
Zaire ebolavirus
Status
Unreviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA. The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N). The replicase mode is dependent on intracellular N protein concentration. In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.UniRule annotation
RNA-directed RNA polymerase that catalyzes the transcription of viral mRNAs, their capping and polyadenylation. The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N). The viral polymerase binds to the genomic RNA at the 3' leader promoter, and transcribes subsequently all viral mRNAs with a decreasing efficiency. The first gene is the most transcribed, and the last the least transcribed. The viral phosphoprotein acts as a processivity factor. Capping is concommitant with initiation of mRNA transcription. Indeed, a GDP polyribonucleotidyl transferase (PRNTase) adds the cap structure when the nascent RNA chain length has reached few nucleotides. Ribose 2'-O methylation of viral mRNA cap precedes and facilitates subsequent guanine-N-7 methylation, both activities being carried by the viral polymerase. Polyadenylation of mRNAs occur by a stuttering mechanism at a slipery stop site present at the end viral genes. After finishing transcription of a mRNA, the polymerase can resume transcription of the downstream gene.UniRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMethyltransferaseUniRule annotationSAAS annotation, Multifunctional enzymeSAAS annotation, Nucleotidyltransferase, RNA-directed RNA polymeraseUniRule annotationSAAS annotation, Transferase
Biological processmRNA cappingUniRule annotationSAAS annotation, mRNA processing, Viral RNA replicationUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding, S-adenosyl-L-methionineUniRule annotationSAAS annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
RNA-directed RNA polymerase LUniRule annotation
Short name:
Protein LUniRule annotation
Alternative name(s):
Large structural proteinUniRule annotation
ReplicaseUniRule annotation
TranscriptaseUniRule annotation
Including the following 4 domains:
RNA-directed RNA polymeraseUniRule annotation (EC:2.7.7.48UniRule annotation)
mRNA (guanine-N(7)-)-methyltransferaseUniRule annotation (EC:2.1.1.56UniRule annotation)
GDP polyribonucleotidyltransferaseUniRule annotation (EC:2.7.7.88UniRule annotation)
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2UniRule annotation (EC:2.1.1.296UniRule annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiZaire ebolavirusImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri186538 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiVirusesRiboviriaNegarnaviricotaHaploviricotinaMonjiviricetesMononegaviralesFiloviridaeEbolavirus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Host cytoplasmUniRule annotationSAAS annotation, VirionUniRule annotationSAAS annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini625 – 809RdRp catalyticInterPro annotationAdd BLAST185
Domaini1805 – 2003Mononegavirus-type SAM-dependent 2'-O-MTaseInterPro annotationAdd BLAST199

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1651 – 1688DisorderedSequence analysisAdd BLAST38

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili2082 – 2109Sequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1655 – 1673PolarSequence analysisAdd BLAST19
Compositional biasi1674 – 1688PolyampholyteSequence analysisAdd BLAST15

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039736 L_poly_C
IPR026890 Mononeg_mRNAcap
IPR014023 Mononeg_RNA_pol_cat
IPR025786 Mononega_L_MeTrfase
IPR017235 RNA-dir_pol_L_filovirus

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14318 Mononeg_mRNAcap, 1 hit
PF00946 Mononeg_RNA_pol, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF037548 RNA_pol_Filoviridae, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR04198 paramyx_RNAcap, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50526 RDRP_SSRNA_NEG_NONSEG, 1 hit
PS51590 SAM_MT_MNV_L, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A0A7LUV3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATQHTQYPD ARLSSPIVLD QCDLVTRACG LYSSYSLNPQ LRNCKLPKHI
60 70 80 90 100
YRLKYDVTVT KFLSDVPVAT LPIDFIVPIL LKALSGNGFC PVEPRCQQFL
110 120 130 140 150
DEIIKYTMQD ALFLKYYLKN VGAQEDCVDD HFQEKILSSI QGNEFLHQMF
160 170 180 190 200
FWYDLAILTR RGRLNRGNSR STWFVHDDLI DILGYGDYVF WKIPISLLPL
210 220 230 240 250
NTQGIPHAAM DWYQTSVFKE AVQGHTHIVS VSTADVLIMC KDLITCRFNT
260 270 280 290 300
TLISKIAEVE DPVCSDYPNF KIVSMLYQSG DYLLSILGSD GYKIIKFLEP
310 320 330 340 350
LCLAKIQLCS KYTERKGRFL TQMHLAVNHT LEEITEIRAL KPSQAHKIRE
360 370 380 390 400
FHRTLIRLEM TPQQLCELFS IQKHWGHPVL HSETAIQKVK KHATVLKALR
410 420 430 440 450
PIVIFETYCV FKYSIAKHYF DSQGSWYSVT SDRNLTPGLN SYIKRNQFPP
460 470 480 490 500
LPMIKELLWE FYHLDHPPLF STKIISDLSI FIKDRATAVE RTCWDAVFEP
510 520 530 540 550
NVLGYNPPHK FSTKRVPEQF LEQENFSIEN VLSYAQKLEY LLPQYRNFSF
560 570 580 590 600
SLKEKELNVG RTFGKLPYPT RNVQTLCEAL LADGLAKAFP SNMMVVTERE
610 620 630 640 650
QKESLLHQAS WHHTSDDFGE HATVRGSSFV TDLEKYNLAF RYEFTAPFIE
660 670 680 690 700
YCNRCYGVKN VFNWMHYTIP QCYMHVSDYY NPPHNLTLEN RNNPPEGPSS
710 720 730 740 750
YRGHMGGIEG LQQKLWTSIS CAQISLVEIK TGFKLRSAVM GDNQCITVLS
760 770 780 790 800
VFPLETDAGE QEQSAEDNAA RVAASLAKVT SACGIFLKPD ETFVHSGFIY
810 820 830 840 850
FGKKQYLNGV QLPQSLKTAT RMAPLSDAIF DDLQGTLASI GTAFERSISE
860 870 880 890 900
TRHIFPCRIT AAFHTFFSVR ILQYHHLGFN KGFDLGQLTL GKPLDFGTIS
910 920 930 940 950
LALAVPQVLG GLSFLNPEKC FYRNLGDPVT SGLFQLKTYL RMIEMDDLFL
960 970 980 990 1000
PLIAKNPGNC TAIDFVLNPS GLNVPGSQDL TSFLRQIVRR TITLSAKNKL
1010 1020 1030 1040 1050
INTLFHASAD FEDEMVCKWL LSSTPVMSRF AADIFSRTPS GKRLQILGYL
1060 1070 1080 1090 1100
EGTRTLLASK IINNNTETPV LDRLRKITLQ RWSLWFSYLD HCDNILAEAL
1110 1120 1130 1140 1150
TQITCTVDLA QILREYSWAH ILEGRPLIGA TLPCMIEQFK VVWLKPYEQC
1160 1170 1180 1190 1200
PQCSNAKQPG GKPFVSVAVK KHIVSAWPNA SRISWTIGDG IPYIGSRTED
1210 1220 1230 1240 1250
KIGQPAIKPK CPSAALREAI ELASRLTWVT QGSSNSDLLI KPFLEARVNL
1260 1270 1280 1290 1300
SVQEILQMTP SHYSGNIVHR YNDQYSPHSF MANRMSNSAT RLIVSTNTLG
1310 1320 1330 1340 1350
EFSGGGQSAR DSNIIFQNVI NYAVALFDIK FRNTEATDIQ YNRAHLHLTK
1360 1370 1380 1390 1400
CCTREVPAQY LTYTSTLDLD LTRYRENELI YDNNPLKGGL NCNISFDNPF
1410 1420 1430 1440 1450
FQGKQLNIIE DDLIRLPHLS GWELAKTIMQ SIISDSNNSS TDPISSGETR
1460 1470 1480 1490 1500
SFTTHFLTYP KIGLLYSFGA FVSYYLGNTI LRTKKLTLDN FLYYLTTQIH
1510 1520 1530 1540 1550
NLPHRSLRIL KPTFKHASVM SRLMSIDPHF SIYIGGAAGD RGLSDAARLF
1560 1570 1580 1590 1600
LRTSISSFLT FVKEWIINRG TIVPLWIVYP LEGQNPTPVN NFLHQIVELL
1610 1620 1630 1640 1650
VHDSSRHQAF KTTINDHVHP HDNLVYTCKS TASNFFHASL AYWRNRHRNS
1660 1670 1680 1690 1700
NRKDLTRNSS TGSSTNNSDG HIKRSQEQTT RDPHDGTERS LVLQMSHEIK
1710 1720 1730 1740 1750
RTTIPQENTH QGPSFQSFLS DSACGTANPK LNFDRSRHNV KSQDHNSASK
1760 1770 1780 1790 1800
REGHQIISHR LVLPFFTLSQ GTRQLTSSNE SQTQDEISKY LRQLRSVIDT
1810 1820 1830 1840 1850
TVYCRFTGIV SSMHYKLDEV LWEIENFKSA VTLAEGEGAG ALLLIQKYQV
1860 1870 1880 1890 1900
KTLFFNTLAT ESSIESEIVS GMTTPRMLLP VMSKFHNDQI EIILNNSASQ
1910 1920 1930 1940 1950
ITDITNPTWF KDQRARLPRQ VEVITMDAET TENINRSKLY EAVHKLILHH
1960 1970 1980 1990 2000
VDPSVLKAVV LKVFLSDTEG MLWLNDNLAP FFATGYLIKP ITSSARSSEW
2010 2020 2030 2040 2050
YLCLTNFLST TRKMPHQNHL SCKQVILTAL QLQIQRSPYW LSHLTQYADC
2060 2070 2080 2090 2100
DLHLSYIRLG FPSLEKVLYH RYNLVDSKRG PLVSVTQHLA HLRAEIRELT
2110 2120 2130 2140 2150
NDYNQQRQSR TQTYHFIRTA KGRITKLVND YLKFFLIVQA LKHNGTWQAE
2160 2170 2180 2190 2200
FKKLPELISV CNRFYHIRDC NCEERFLVQT LYLHRMQDSE VKLIERLTGL
2210
LSLFPDGLYR FD
Length:2,212
Mass (Da):252,522
Last modified:March 4, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i18E2ABFD47C8FD80
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
KP260799 Viral cRNA Translation: AIZ68612.1
KP260800 Viral cRNA Translation: AIZ68620.1
KP260801 Viral cRNA Translation: AIZ68628.1
KR006951 Viral cRNA Translation: AJZ74621.1
KR006952 Viral cRNA Translation: AJZ74630.1
KR006956 Viral cRNA Translation: AJZ74664.1
KR074996 Viral cRNA Translation: AKC01440.1
KR534512 Viral cRNA Translation: AKG65147.1
KR534513 Viral cRNA Translation: AKG65156.1
KR534518 Viral cRNA Translation: AKG65201.1
KR534523 Viral cRNA Translation: AKG65246.1
KR534530 Viral cRNA Translation: AKG65309.1
KR534536 Viral cRNA Translation: AKG65363.1
KR534539 Viral cRNA Translation: AKG65390.1
KR534542 Viral cRNA Translation: AKG65417.1
KR534550 Viral cRNA Translation: AKG65489.1
KR534551 Viral cRNA Translation: AKG65498.1
KR534552 Viral cRNA Translation: AKG65507.1
KR534553 Viral cRNA Translation: AKG65516.1
KR534557 Viral cRNA Translation: AKG65552.1
KR534560 Viral cRNA Translation: AKG65579.1
KR534561 Viral cRNA Translation: AKG65588.1
KR534563 Viral cRNA Translation: AKG65606.1
KR534565 Viral cRNA Translation: AKG65624.1
KR534568 Viral cRNA Translation: AKG65651.1
KR534575 Viral cRNA Translation: AKG65714.1
KR534588 Viral cRNA Translation: AKG65831.1
KR817075 Viral cRNA Translation: AKI82711.1
KR817090 Viral cRNA Translation: AKI82846.1
KR817091 Viral cRNA Translation: AKI82855.1
KR817093 Viral cRNA Translation: AKI82873.1
KR817095 Viral cRNA Translation: AKI82891.1
KR817096 Viral cRNA Translation: AKI82900.1
KR817097 Viral cRNA Translation: AKI82909.1
KR817098 Viral cRNA Translation: AKI82918.1
KR817099 Viral cRNA Translation: AKI82927.1
KR817100 Viral cRNA Translation: AKI82936.1
KR817121 Viral cRNA Translation: AKI83125.1
KR817123 Viral cRNA Translation: AKI83143.1
KR817128 Viral cRNA Translation: AKI83188.1
KR817130 Viral cRNA Translation: AKI83206.1
KR817132 Viral cRNA Translation: AKI83224.1
KR817133 Viral cRNA Translation: AKI83233.1
KR817134 Viral cRNA Translation: AKI83242.1
KR817135 Viral cRNA Translation: AKI83251.1
KR817136 Viral cRNA Translation: AKI83260.1
KR817137 Viral cRNA Translation: AKI83269.1
KR817139 Viral cRNA Translation: AKI83287.1
KR817141 Viral cRNA Translation: AKI83305.1
KR817142 Viral cRNA Translation: AKI83314.1
KR817144 Viral cRNA Translation: AKI83332.1
KR817146 Viral cRNA Translation: AKI83350.1
KR817147 Viral cRNA Translation: AKI83359.1
KR817148 Viral cRNA Translation: AKI83368.1
KR817149 Viral cRNA Translation: AKI83377.1
KR817150 Viral cRNA Translation: AKI83386.1
KR817161 Viral cRNA Translation: AKI83485.1
KR817163 Viral cRNA Translation: AKI83503.1
KR817165 Viral cRNA Translation: AKI83521.1
KR817170 Viral cRNA Translation: AKI83566.1
KR817171 Viral cRNA Translation: AKI83575.1
KR817173 Viral cRNA Translation: AKI83593.1
KR817175 Viral cRNA Translation: AKI83611.1
KR817176 Viral cRNA Translation: AKI83620.1
KR817177 Viral cRNA Translation: AKI83629.1
KT587346 Viral cRNA Translation: ALB07149.1
KT633510 Viral cRNA Translation: ALF04595.1
KT725259 Viral cRNA Translation: ALG00924.1
KT725263 Viral cRNA Translation: ALG00960.1
KT725266 Viral cRNA Translation: ALG00987.1
KT725270 Viral cRNA Translation: ALG01023.1
KT725271 Viral cRNA Translation: ALG01032.1
KT725281 Viral cRNA Translation: ALG01122.1
KT725287 Viral cRNA Translation: ALG01176.1
KT725295 Viral cRNA Translation: ALG01248.1
KT725299 Viral cRNA Translation: ALG01284.1
KT725317 Viral cRNA Translation: ALG01446.1
KT725319 Viral cRNA Translation: ALG01464.1
KT725328 Viral cRNA Translation: ALG01545.1
KT725340 Viral cRNA Translation: ALG01653.1
KT725343 Viral cRNA Translation: ALG01680.1
KT725374 Viral cRNA Translation: ALG01959.1
KT725376 Viral cRNA Translation: ALG01977.1
KT725382 Viral cRNA Translation: ALG02031.1
KT725385 Viral cRNA Translation: ALG02058.1
KT725387 Viral cRNA Translation: ALG02076.1
KX009906 Viral cRNA Translation: AMT75706.1
KX009909 Viral cRNA Translation: AMT75733.1
KX009912 Viral cRNA Translation: AMT75760.1
KX013091 Viral cRNA Translation: AMY60269.1
KX013092 Viral cRNA Translation: AMY60278.1
KX013093 Viral cRNA Translation: AMY60287.1
KX013094 Viral cRNA Translation: AMY60296.1
KX013095 Viral cRNA Translation: AMY60305.1
KX013096 Viral cRNA Translation: AMY60314.1
KX013097 Viral cRNA Translation: AMY60323.1
KX013098 Viral cRNA Translation: AMY60332.1
KX013099 Viral cRNA Translation: AMY60341.1
KX013101 Viral cRNA Translation: AMY60359.1
KY744596 Viral cRNA Translation: ARC95302.1
KY744597 Viral cRNA Translation: ARC95311.1
MH425138 Viral cRNA Translation: AWZ62332.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KP260799 Viral cRNA Translation: AIZ68612.1
KP260800 Viral cRNA Translation: AIZ68620.1
KP260801 Viral cRNA Translation: AIZ68628.1
KR006951 Viral cRNA Translation: AJZ74621.1
KR006952 Viral cRNA Translation: AJZ74630.1
KR006956 Viral cRNA Translation: AJZ74664.1
KR074996 Viral cRNA Translation: AKC01440.1
KR534512 Viral cRNA Translation: AKG65147.1
KR534513 Viral cRNA Translation: AKG65156.1
KR534518 Viral cRNA Translation: AKG65201.1
KR534523 Viral cRNA Translation: AKG65246.1
KR534530 Viral cRNA Translation: AKG65309.1
KR534536 Viral cRNA Translation: AKG65363.1
KR534539 Viral cRNA Translation: AKG65390.1
KR534542 Viral cRNA Translation: AKG65417.1
KR534550 Viral cRNA Translation: AKG65489.1
KR534551 Viral cRNA Translation: AKG65498.1
KR534552 Viral cRNA Translation: AKG65507.1
KR534553 Viral cRNA Translation: AKG65516.1
KR534557 Viral cRNA Translation: AKG65552.1
KR534560 Viral cRNA Translation: AKG65579.1
KR534561 Viral cRNA Translation: AKG65588.1
KR534563 Viral cRNA Translation: AKG65606.1
KR534565 Viral cRNA Translation: AKG65624.1
KR534568 Viral cRNA Translation: AKG65651.1
KR534575 Viral cRNA Translation: AKG65714.1
KR534588 Viral cRNA Translation: AKG65831.1
KR817075 Viral cRNA Translation: AKI82711.1
KR817090 Viral cRNA Translation: AKI82846.1
KR817091 Viral cRNA Translation: AKI82855.1
KR817093 Viral cRNA Translation: AKI82873.1
KR817095 Viral cRNA Translation: AKI82891.1
KR817096 Viral cRNA Translation: AKI82900.1
KR817097 Viral cRNA Translation: AKI82909.1
KR817098 Viral cRNA Translation: AKI82918.1
KR817099 Viral cRNA Translation: AKI82927.1
KR817100 Viral cRNA Translation: AKI82936.1
KR817121 Viral cRNA Translation: AKI83125.1
KR817123 Viral cRNA Translation: AKI83143.1
KR817128 Viral cRNA Translation: AKI83188.1
KR817130 Viral cRNA Translation: AKI83206.1
KR817132 Viral cRNA Translation: AKI83224.1
KR817133 Viral cRNA Translation: AKI83233.1
KR817134 Viral cRNA Translation: AKI83242.1
KR817135 Viral cRNA Translation: AKI83251.1
KR817136 Viral cRNA Translation: AKI83260.1
KR817137 Viral cRNA Translation: AKI83269.1
KR817139 Viral cRNA Translation: AKI83287.1
KR817141 Viral cRNA Translation: AKI83305.1
KR817142 Viral cRNA Translation: AKI83314.1
KR817144 Viral cRNA Translation: AKI83332.1
KR817146 Viral cRNA Translation: AKI83350.1
KR817147 Viral cRNA Translation: AKI83359.1
KR817148 Viral cRNA Translation: AKI83368.1
KR817149 Viral cRNA Translation: AKI83377.1
KR817150 Viral cRNA Translation: AKI83386.1
KR817161 Viral cRNA Translation: AKI83485.1
KR817163 Viral cRNA Translation: AKI83503.1
KR817165 Viral cRNA Translation: AKI83521.1
KR817170 Viral cRNA Translation: AKI83566.1
KR817171 Viral cRNA Translation: AKI83575.1
KR817173 Viral cRNA Translation: AKI83593.1
KR817175 Viral cRNA Translation: AKI83611.1
KR817176 Viral cRNA Translation: AKI83620.1
KR817177 Viral cRNA Translation: AKI83629.1
KT587346 Viral cRNA Translation: ALB07149.1
KT633510 Viral cRNA Translation: ALF04595.1
KT725259 Viral cRNA Translation: ALG00924.1
KT725263 Viral cRNA Translation: ALG00960.1
KT725266 Viral cRNA Translation: ALG00987.1
KT725270 Viral cRNA Translation: ALG01023.1
KT725271 Viral cRNA Translation: ALG01032.1
KT725281 Viral cRNA Translation: ALG01122.1
KT725287 Viral cRNA Translation: ALG01176.1
KT725295 Viral cRNA Translation: ALG01248.1
KT725299 Viral cRNA Translation: ALG01284.1
KT725317 Viral cRNA Translation: ALG01446.1
KT725319 Viral cRNA Translation: ALG01464.1
KT725328 Viral cRNA Translation: ALG01545.1
KT725340 Viral cRNA Translation: ALG01653.1
KT725343 Viral cRNA Translation: ALG01680.1
KT725374 Viral cRNA Translation: ALG01959.1
KT725376 Viral cRNA Translation: ALG01977.1
KT725382 Viral cRNA Translation: ALG02031.1
KT725385 Viral cRNA Translation: ALG02058.1
KT725387 Viral cRNA Translation: ALG02076.1
KX009906 Viral cRNA Translation: AMT75706.1
KX009909 Viral cRNA Translation: AMT75733.1
KX009912 Viral cRNA Translation: AMT75760.1
KX013091 Viral cRNA Translation: AMY60269.1
KX013092 Viral cRNA Translation: AMY60278.1
KX013093 Viral cRNA Translation: AMY60287.1
KX013094 Viral cRNA Translation: AMY60296.1
KX013095 Viral cRNA Translation: AMY60305.1
KX013096 Viral cRNA Translation: AMY60314.1
KX013097 Viral cRNA Translation: AMY60323.1
KX013098 Viral cRNA Translation: AMY60332.1
KX013099 Viral cRNA Translation: AMY60341.1
KX013101 Viral cRNA Translation: AMY60359.1
KY744596 Viral cRNA Translation: ARC95302.1
KY744597 Viral cRNA Translation: ARC95311.1
MH425138 Viral cRNA Translation: AWZ62332.1

3D structure databases

Database of comparative protein structure models

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ModBasei
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
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Family and domain databases

InterProiView protein in InterPro
IPR039736 L_poly_C
IPR026890 Mononeg_mRNAcap
IPR014023 Mononeg_RNA_pol_cat
IPR025786 Mononega_L_MeTrfase
IPR017235 RNA-dir_pol_L_filovirus
PfamiView protein in Pfam
PF14318 Mononeg_mRNAcap, 1 hit
PF00946 Mononeg_RNA_pol, 1 hit
PIRSFiPIRSF037548 RNA_pol_Filoviridae, 1 hit
TIGRFAMsiTIGR04198 paramyx_RNAcap, 1 hit
PROSITEiView protein in PROSITE
PS50526 RDRP_SSRNA_NEG_NONSEG, 1 hit
PS51590 SAM_MT_MNV_L, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0A7LUV3_9MONO
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0A7LUV3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 4, 2015
Last sequence update: March 4, 2015
Last modified: October 16, 2019
This is version 36 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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