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UniProtKB - A0A1V4KKV1 (A0A1V4KKV1_PATFA)

Entry version 8 (31 Jul 2019)
Sequence version 1 (07 Jun 2017)
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Protein
Submitted name:

DNA excision repair protein ERCC-6

Gene

ERCC6

Organism
Patagioenas fasciata monilis
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
DNA excision repair protein ERCC-6Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ERCC6Imported
ORF Names:AV530_015859Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPatagioenas fasciata monilisImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri372326 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archelosauria › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Columbiformes › Columbidae › Patagioenas ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000190648 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini569 – 745Helicase ATP-bindingInterPro annotationAdd BLAST177
Domaini894 – 1053Helicase C-terminalInterPro annotationAdd BLAST160

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni45 – 112DisorderedSequence analysisAdd BLAST68
Regioni345 – 462DisorderedSequence analysisAdd BLAST118
Regioni484 – 506DisorderedSequence analysisAdd BLAST23
Regioni1083 – 1136DisorderedSequence analysisAdd BLAST54
Regioni1253 – 1305DisorderedSequence analysisAdd BLAST53
Regioni1397 – 1445DisorderedSequence analysisAdd BLAST49

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili166 – 186Sequence analysisAdd BLAST21
Coiled coili227 – 247Sequence analysisAdd BLAST21
Coiled coili1156 – 1183Sequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi379 – 394BasicSequence analysisAdd BLAST16
Compositional biasi400 – 424PolyampholyteSequence analysisAdd BLAST25
Compositional biasi425 – 441AcidicSequence analysisAdd BLAST17
Compositional biasi442 – 462PolyampholyteSequence analysisAdd BLAST21
Compositional biasi1085 – 1103PolyampholyteSequence analysisAdd BLAST19
Compositional biasi1104 – 1136PolarSequence analysisAdd BLAST33
Compositional biasi1272 – 1305PolyampholyteSequence analysisAdd BLAST34
Compositional biasi1411 – 1430PolyampholyteSequence analysisAdd BLAST20
Compositional biasi1431 – 1445PolarSequence analysisAdd BLAST15

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.40.50.10810, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00271 Helicase_C, 1 hit
PF00176 SNF2_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF52540 SSF52540, 2 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A1V4KKV1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAARRGRAGE RWCRGSRCPA VRAGPVACAF GADGRNLVTL KAPNNSSSGL 
        60         70         80         90        100
AVRMPTDNSH LPDSIQEQDP VTSASNNCQH NAEESGTEQK NDICNSDLGD 
       110        120        130        140        150
SIRTPNSDSL SLTSTAFPLE VPRRGQPLLQ INRQQIQSIS YSAQAAELKG 
       160        170        180        190        200
LGVDVYDQDV LEQGVLQQVD NAISEANKAA KIADAEKEYQ SVLDDLRSCT 
       210        220        230        240        250
TSLKQIDKII EQLSPQAADN KNISRKLDSV KRQKYNKEQQ LKKIKAKQKR 
       260        270        280        290        300
LQAVLGGTEI LNKVNEIELE EDEEPGPSCL GSMLMPVQET EWEELIRTGQ 
       310        320        330        340        350
MTPFGTTIPQ KPERKTRRLM LNEASDFEKY LADQAKLSSE RKKLSLHKGA 
       360        370        380        390        400
KKKAQAKNVQ KCVASASTKK EKGGKALSKT DKRLKKHMRK LQKHALQIQS 
       410        420        430        440        450
KAEIPKEKKY LEAKKFRREQ EDDSGESEYV PDEELFDPAA AEEEEEHASS 
       460        470        480        490        500
PGENDSDYEL RNLSSKRKYS VKRAFKEAED DADFFPSSEE EEHTLGKRKG 
       510        520        530        540        550
KRWRDDGDED YYKQRLRRWQ KERLKDKEHQ TAEELSEESD AEFEEGFKVP 
       560        570        580        590        600
GFLFKKLFKY QQTGVRWLWE LHCQQAGGIL GDEMGLGKTI QIIAFLAGLS 
       610        620        630        640        650
YSKIRTRGSN YRHQGLGPTV IVCPATVMHQ WVKEFHTWWP PFRVAILHET 
       660        670        680        690        700
GSYTDKKVKL IREIASCHGI LITSYSYIRL MQDNIHRYDW HYVILDEGHK 
       710        720        730        740        750
IRNPNAAVTL ACKQFRTPHR IILSGSPMQN NLKELWSLFD FIFPGKLGTL 
       760        770        780        790        800
PVFMEQFSVP ITMGGYANAS PVQVKTAYKC ACVLRDTINP YLLRRMKADV 
       810        820        830        840        850
KMSLSLPDKN EQVLFCRLTD EQRQVYQNFI NSKEVYEILN GDMQLFSGLV 
       860        870        880        890        900
ALRKICNHPD LFSGGPRILK GVPDAEVEQA DQFGYWKRSG KMIVVESLLK 
       910        920        930        940        950
IWHKQGHRVL FFTQSRQMLQ IFEVFVRERN YSYFRMDGTT TIASRQPLVT 
       960        970        980        990       1000
RFNEDKSIFL FLLTTRVGGI GVNLTGADRV IIYDPDWNPS TDTQARERAW 
      1010       1020       1030       1040       1050
RIGQKKQVTV YRLLTAGTIE EKIYHRQIFK QFLTNRVLKD PKQRRFFKSN 
      1060       1070       1080       1090       1100
DLYELFTLSS PDVSQGTETS AIFAGTGSDV QVPKRQLKQK LEKPPDSDTS 
      1110       1120       1130       1140       1150
KGDLHLAESS SPKYSKSSDS YSTMHMGNSS SKAIETSEEI QRNLETLDQN 
      1160       1170       1180       1190       1200
GYAKDNAQAA TNINSLNKNK EESLERAEKC MSQSLPGDAR SSESGKCLNT 
      1210       1220       1230       1240       1250
VLAGGVHGAA NATGKGDFSL TCGAAGPLEE QVPKTDDGKL DNNHYKCTSK 
      1260       1270       1280       1290       1300
TKHRVDMLSH KSHKDKSKKK HHKDAKFEGE RIPHLVKQKQ YRKENSEEEQ 
      1310       1320       1330       1340       1350
EDSKKNDDYV LEKLFRKSGV HSVMKHDAIM EASSADYVLV EAEANRVAQD 
      1360       1370       1380       1390       1400
ALRALKVSRQ RCLGAASGVP TWTGTSGLSG APSGIKSRFG RKRNPMLLSS 
      1410       1420       1430       1440       1450
HSTCASPAKK CKDADTVKRE DVKKSSSNGH FDGKSGESSP SALDSSTLLA 
      1460       1470       1480       1490       1500
KMRARNHLTL SQQTRHEGDE NHHQALTPVP GSTEYDELLV DLRNFVAFGA 
      1510       1520       1530       1540       1550
RVDGEASTQE LLHEFESKLT VAQSSVFREL LRNVCTFHRR PNGEGVWKLK 

PEFH
Length:1,554
Mass (Da):175,401
Last modified:June 7, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1F0A6058A7E44E11
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
LSYS01003057 Genomic DNA Translation: OPJ84447.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LSYS01003057 Genomic DNA Translation: OPJ84447.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Family and domain databases

Gene3Di3.40.50.10810, 1 hit
InterProiView protein in InterPro
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N
PfamiView protein in Pfam
PF00271 Helicase_C, 1 hit
PF00176 SNF2_N, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A1V4KKV1_PATFA
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1V4KKV1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 7, 2017
Last sequence update: June 7, 2017
Last modified: July 31, 2019
This is version 8 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health

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