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Entry version 9 (16 Oct 2019)
Sequence version 1 (28 Feb 2018)
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Protein
Submitted name:

Golgin A3

Gene

GOLGA3

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Golgin A3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GOLGA3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPan troglodytes (Chimpanzee)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9598 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002277 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:5403 GOLGA3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 127DisorderedSequence analysisAdd BLAST127
Regioni175 – 197DisorderedSequence analysisAdd BLAST23
Regioni222 – 334DisorderedSequence analysisAdd BLAST113
Regioni798 – 817DisorderedSequence analysisAdd BLAST20
Regioni1381 – 1405DisorderedSequence analysisAdd BLAST25
Regioni1445 – 1503DisorderedSequence analysisAdd BLAST59

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili409 – 457Sequence analysisAdd BLAST49
Coiled coili500 – 534Sequence analysisAdd BLAST35
Coiled coili542 – 576Sequence analysisAdd BLAST35
Coiled coili619 – 639Sequence analysisAdd BLAST21
Coiled coili676 – 776Sequence analysisAdd BLAST101
Coiled coili867 – 947Sequence analysisAdd BLAST81
Coiled coili951 – 996Sequence analysisAdd BLAST46
Coiled coili1015 – 1035Sequence analysisAdd BLAST21
Coiled coili1049 – 1125Sequence analysisAdd BLAST77
Coiled coili1154 – 1174Sequence analysisAdd BLAST21
Coiled coili1179 – 1206Sequence analysisAdd BLAST28
Coiled coili1221 – 1283Sequence analysisAdd BLAST63
Coiled coili1291 – 1378Sequence analysisAdd BLAST88

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi24 – 40Pro-richSequence analysisAdd BLAST17
Compositional biasi54 – 75PolarSequence analysisAdd BLAST22
Compositional biasi80 – 94Pro-richSequence analysisAdd BLAST15
Compositional biasi241 – 258PolyampholyteSequence analysisAdd BLAST18
Compositional biasi260 – 334PolarSequence analysisAdd BLAST75

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183078

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR033288 Golga3

The PANTHER Classification System

More...
PANTHERi
PTHR18902:SF26 PTHR18902:SF26, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

A0A2I3TPJ6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDGASAEQDG LQEDRSHSGP SSLPEAPLKP PGPLVPPDQQ DPLVPRDQQD
60 70 80 90 100
KAQCAEVNRA STEGESPNGP GQGGLCQNGP TPPFPDPPSS LDPTTSPVGP
110 120 130 140 150
DASPGVAGFH DNLRKSQGTS AEGSVRKEAL QSLRLSLPMQ ETQLCSTDSP
160 170 180 190 200
LPLEKEEQVR LQARKWLEEQ LKQYRVKRQQ ERSSQPATKT RLFSTLDPEL
210 220 230 240 250
MLNPENLPRA STLAMTKEYS FLRTSVPRGP KVGSLGLPAH PREKKSSKSS
260 270 280 290 300
KIRSLADYRT EDSNAGNSGG NVPAPDSTKG SLKQNRSSAA SVVSEISLSP
310 320 330 340 350
DTDDRLENTS LAGDSVSEVD GNDSDSSSYS SASTRGTYGI LSKTVGTQDT
360 370 380 390 400
PYMVNGQEIP ADTLGQFPSI KDVLQAAAAE HQDQGQEVNG EVRSRRDSIC
410 420 430 440 450
SSVSLESSAA ETQEEMLQVL KEKMRLEGQL EALSLEASQA LKEKAELQAQ
460 470 480 490 500
LAALSTKLQA QVECSHSSQQ RQDSLSSEVD TLKQSCWDLE RAMTDLQNML
510 520 530 540 550
EAKNASLASS NNDLQVAEEQ YQRLMAKVED MQRSMLSKDN TVHDLRQQMT
560 570 580 590 600
ALQSQLQQVQ LERTTLTSKL KASQAEISSL QSVRQWYQQQ LALAQEARVR
610 620 630 640 650
LQGEMAHIQV GQMTQAGLLE HLKLENVSLS QQLTETQHRS MKEKGRIAAQ
660 670 680 690 700
LQGIEADMLD QEAAFMQIQE AKTMVEEDLQ RRLEEFEGER ERLQRMADSA
710 720 730 740 750
ASLEQQLEQV KLTLLQRDQQ LEALQQEHLD LMKQLTLTQE ALQSREQSLD
760 770 780 790 800
ALQTHYDELQ ARLGELQGEA ASREDTICLL QNEKIILEAA LQAAKSGKEE
810 820 830 840 850
LDRGARRLEE GTEETSETLE KLREELAIKS GQVMRLPLLK KQMQKIKEHL
860 870 880 890 900
RLWQVMVEAY RRDATSKDQL ISELKATRKR LDSELKELRQ ELMQVHGEKR
910 920 930 940 950
AAEAELSRLH REAAQVRQQM ADLEGHLQLA QKERDEMETH LQSLQFDKEQ
960 970 980 990 1000
MVVVTEANEA LKKQIEELQQ EARKAITEQK QKMRRLGSDL TSAQKEMKTK
1010 1020 1030 1040 1050
HKAYENAVGI LSRRLQEALA AKEAADAELG QLRAQGGSSD SSLALHERIQ
1060 1070 1080 1090 1100
ALEAELQAVS HSKTLLEKEL QEVIALTSQE LEESREKVLE LEDELQESRG
1110 1120 1130 1140 1150
FRKKIKRLEE SNKKLALELE HEKGKLTGLG QSNAALREHN SILETALAKR
1160 1170 1180 1190 1200
EADLVQLNLQ VQAVLQRKEE EDRQMKHLVQ ALQASLEKEK EKVNSLKEQV
1210 1220 1230 1240 1250
AAAKVEAGHN RRHFKAASLE LSEVKKELQA KEHLVQKLQA EADDLQIREG
1260 1270 1280 1290 1300
KHSQEIAQFQ AELAEARAQL QLLQKQLDEQ LSKQPVGNQE MENLKWEVDQ
1310 1320 1330 1340 1350
KEREIQSLKQ QLDLTEQQGR KELEGLQQLL QNVKSELEMA QEDLSMTQKD
1360 1370 1380 1390 1400
KFMLQAKVSE LKNNMKTLLQ QNQQLKLDLR RGAAKTRKEP KGEASSSNPA
1410 1420 1430 1440 1450
TPIKIPDCPV PASLLEELLR PPPAVSKEPL KNLNSCLQQL KQEMDSLQRQ
1460 1470 1480 1490 1500
MEEHALTVHE SLSSWTPLEP ATASPVPPGG HAGPRGDPQR HSQSRASKEG

PGE
Length:1,503
Mass (Da):168,012
Last modified:February 28, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA6FF5CEC1EE36CE3
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H2Q786H2Q786_PANTR
Golgin A3
GOLGA3
1,498Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3SBQ6A0A2I3SBQ6_PANTR
Golgin A3
GOLGA3
1,392Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AACZ04060456 Genomic DNA No translation available.
AACZ04060457 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSPTRT00000092947; ENSPTRP00000091164; ENSPTRG00000005659

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04060456 Genomic DNA No translation available.
AACZ04060457 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENSPTRT00000092947; ENSPTRP00000091164; ENSPTRG00000005659

Organism-specific databases

VGNCiVGNC:5403 GOLGA3

Phylogenomic databases

GeneTreeiENSGT00950000183078

Family and domain databases

InterProiView protein in InterPro
IPR033288 Golga3
PANTHERiPTHR18902:SF26 PTHR18902:SF26, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2I3TPJ6_PANTR
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2I3TPJ6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 28, 2018
Last sequence update: February 28, 2018
Last modified: October 16, 2019
This is version 9 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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