DAGKc domain-containing protein

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• acetyltransferase activity Source: Ensembl
• D-erythro-sphingosine kinase activity Source: Ensembl
• NAD+ kinase activity Source: InterPro
• sphinganine kinase activity Source: Ensembl

GO - Biological processⁱ

• blood vessel development Source: Ensembl
• brain development Source: Ensembl
• cellular response to hydrogen peroxide Source: Ensembl
• cellular response to vascular endothelial growth factor stimulus Source: Ensembl
• DNA biosynthetic process Source: Ensembl
• inflammatory response Source: Ensembl
• negative regulation of apoptotic process Source: Ensembl
• negative regulation of ceramide biosynthetic process Source: Ensembl
• positive regulation of cell population proliferation Source: Ensembl
• positive regulation of mitotic nuclear division Source: Ensembl
• protein acetylation Source: Ensembl
• regulation of endocytosis Source: Ensembl
• regulation of endosomal vesicle fusion Source: Ensembl
• regulation of interleukin-1 beta production Source: Ensembl
• regulation of microglial cell activation Source: Ensembl
• regulation of phagocytosis Source: Ensembl
• sphingolipid mediated signaling pathway Source: Ensembl

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Region

Compositional bias

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)ⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

        10         20         30         40         50
MSAQVLGFLR SWAPLPLAAP RDPAAAGNDA GDLTATAPDG EGEPHSRPCD 
        60         70         80         90        100
ARLGSTDKEL KAGAAATGSA PTAPGTPRQR EPRVEVMDPA GGPRGVLPRS 
       110        120        130        140        150
CRVLVLLNPR GGKGKALQLF RSHVQPLLAE AEISFTLMLT ERRNHARELV 
       160        170        180        190        200
RSEELGRWDA LVVMSGDGLM HEVVNGLMER PDWETAIQKP LCSLPAGSGN 
       210        220        230        240        250
ALAASLNHYA GYEQVTNEDL LTNCTRLLCR RLLSPMNLLS LHTASGLRLF 
       260        270        280        290        300
SVLSLAWGFI ADVDLESEKY RRLGEMRFTL GTFLRLAALR TYRGRLAYLP 
       310        320        330        340        350
VGRASSKTPA SPVVVQQGPV DAHLVPLEEP VPSHWTVVPD QDFVLVLALL 
       360        370        380        390        400
HSHLGSEMFA APMGRCAAGV MHLFYVRAGV SRAMLLRLFL AMEKGRHMEY 
       410        420        430        440        450
ECPYLVYMPV VAFRLEPEDG RGVFTVDGEL MVSEAVQGQV HPNYFWMVSD 
       460        470
GVEPLPSWKP QQTPPPEEPL                                  

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ