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Entry version 7 (31 Jul 2019)
Sequence version 1 (07 Nov 2018)
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Protein
Submitted name:

phosphoinositide 3-kinase regulatory subunit 5

Gene

PIK3R5

Organism
Balaenoptera acutorostrata scammoni (North Pacific minke whale) (Balaenoptera davidsoni)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
phosphoinositide 3-kinase regulatory subunit 5Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PIK3R5Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBalaenoptera acutorostrata scammoni (North Pacific minke whale) (Balaenoptera davidsoni)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri310752 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaCetaceaMysticetiBalaenopteridaeBalaenoptera
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000261681 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni316 – 346DisorderedSequence analysisAdd BLAST31
Regioni389 – 421DisorderedSequence analysisAdd BLAST33
Regioni437 – 493DisorderedSequence analysisAdd BLAST57
Regioni568 – 601DisorderedSequence analysisAdd BLAST34

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi316 – 337AcidicSequence analysisAdd BLAST22
Compositional biasi396 – 414PolyampholyteSequence analysisAdd BLAST19
Compositional biasi578 – 595Pro-richSequence analysisAdd BLAST18

Phylogenomic databases

KEGG Orthology (KO)

More...
KOi
K21290

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR019522 PIK3R5/6

The PANTHER Classification System

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PANTHERi
PTHR15593 PTHR15593, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10486 PI3K_1B_p101, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A383YUN0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQPGATTCTE DRIQHALERC LHGLSLSRRS TSWSAGLCLN CWSLQELVSR
60 70 80 90 100
DPGHFLILLE QILQKTHEVQ EKGTYDLLAP LALLFSSTVL CTPHFPPDSD
110 120 130 140 150
LLLKAAKTYH RFLTWPVPYC SICQELLTFI DAELKAPGIS YQRLVRAEQG
160 170 180 190 200
LSTRSHRSST VTVLLLNPVE VQAEFLTVAD KLSTPGHSPH SAYTTLLLHA
210 220 230 240 250
FQATFGAHCD LPGLHCQLQS KTLAELEDIF TETAEAQELA SGIGDAAEAR
260 270 280 290 300
QWLRTKLQAV GEKAGFLGAL DTAKPGKLRT IPIPVARCYT YSWNQDSFDI
310 320 330 340 350
LQEILLKEQE LLQPGILGDD EEDGEDEEDE EDLETEGPCA ERDSLLSGGS
360 370 380 390 400
AAFHDSTLSL ASSQASGPTL SRQLLTSFVA GLSDGMDSGY VEDGEESSFE
410 420 430 440 450
WPKRPGSQER RGHRRPGQKF NRIYKLFKST SQLVLRRDSR TLEGSPDSAR
460 470 480 490 500
ARPLRRPASL CSPCSPLDGP ALPPSRAQRS RSLPQHKLDP ELPGWLLAPA
510 520 530 540 550
SRHRRRCPFL SGDEDPKAST LRVVVFGSDR ISGKVARAYS KLRRLESNRP
560 570 580 590 600
LLTRFFKLQF FYVPMKRSRG TSASPAPRSQ TPPLPTDPPR HPGPAELGAA
610 620 630 640 650
PWEESTNDIS HYLGMLDPWY ERNVLGLMHL PPEVLCQQSL KAESRPLEGS
660 670 680 690 700
PAQLPILADM LLYYCRFAAR PVLLQVYQTE LTFITGEKTT EIFIHSLELG
710 720 730 740 750
HSAATRAIKA SGPGSKRLGI DGDREAIPLT LQIIYSKGAI SGRSRWSNME
760 770 780 790 800
KVCTSVNLSK ACRQQEDLDS STEALTLNLT EVVKRQNPKS KKGFNQISIS
810 820 830 840 850
QIKVDKVQII GSNSCPFAVC LDQDERKILQ SVVRCEVSPC YKPEKSSLCP
860 870 880
PPQRPSYLQA QAAPDLCSLL CLPIMTFSGA LP
Length:882
Mass (Da):97,491
Last modified:November 7, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9EB79A5BD3EA59D9
GO

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_007166399.1, XM_007166337.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

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GeneIDi
103014949

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
bacu:103014949

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_007166399.1, XM_007166337.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

GeneIDi103014949
KEGGibacu:103014949

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
23533

Phylogenomic databases

KOiK21290

Family and domain databases

InterProiView protein in InterPro
IPR019522 PIK3R5/6
PANTHERiPTHR15593 PTHR15593, 1 hit
PfamiView protein in Pfam
PF10486 PI3K_1B_p101, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A383YUN0_BALAS
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A383YUN0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 7, 2018
Last sequence update: November 7, 2018
Last modified: July 31, 2019
This is version 7 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
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