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Entry version 7 (16 Oct 2019)
Sequence version 1 (13 Feb 2019)
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Protein
Submitted name:

Uncharacterized protein

Gene

BN2614_LOCUS13

Organism
Gulo gulo (Wolverine) (Gluton)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:BN2614_LOCUS13Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiGulo gulo (Wolverine) (Gluton)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri48420 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaMustelidaeMartinaeGulo

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini136 – 191MIRInterPro annotationAdd BLAST56
Domaini198 – 243MIRInterPro annotationAdd BLAST46
Domaini249 – 303MIRInterPro annotationAdd BLAST55
Domaini309 – 366MIRInterPro annotationAdd BLAST58
Domaini374 – 431MIRInterPro annotationAdd BLAST58
Domaini620 – 836B30.2/SPRYInterPro annotationAdd BLAST217
Domaini1052 – 1247B30.2/SPRYInterPro annotationAdd BLAST196
Domaini1396 – 1609B30.2/SPRYInterPro annotationAdd BLAST214

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 45DisorderedSequence analysisAdd BLAST45
Regioni1347 – 1419DisorderedSequence analysisAdd BLAST73
Regioni1906 – 1960DisorderedSequence analysisAdd BLAST55
Regioni2112 – 2131DisorderedSequence analysisAdd BLAST20
Regioni2428 – 2450DisorderedSequence analysisAdd BLAST23
Regioni2866 – 2898DisorderedSequence analysisAdd BLAST33
Regioni3516 – 3539DisorderedSequence analysisAdd BLAST24

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili2951 – 2971Sequence analysisAdd BLAST21
Coiled coili3409 – 3429Sequence analysisAdd BLAST21
Coiled coili3712 – 3732Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1360 – 1389PolyampholyteSequence analysisAdd BLAST30
Compositional biasi1909 – 1956AcidicSequence analysisAdd BLAST48
Compositional biasi2112 – 2126PolyampholyteSequence analysisAdd BLAST15
Compositional biasi2866 – 2881PolyampholyteSequence analysisAdd BLAST16

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation

Family and domain databases

Conserved Domains Database

More...
CDDi
cd12877 SPRY1_RyR, 1 hit
cd12878 SPRY2_RyR, 1 hit
cd12879 SPRY3_RyR, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001870 B30.2/SPRY
IPR013320 ConA-like_dom_sf
IPR011992 EF-hand-dom_pair
IPR014821 Ins145_P3_rcpt
IPR036300 MIR_dom_sf
IPR016093 MIR_motif
IPR013662 RIH_assoc-dom
IPR000699 RIH_dom
IPR013333 Ryan_recept
IPR003032 Ryanodine_rcpt
IPR035910 RyR/IP3R_RIH_dom_sf
IPR033215 RyR1
IPR035761 SPRY1_RyR
IPR035764 SPRY2_RyR
IPR035762 SPRY3_RyR
IPR003877 SPRY_dom

The PANTHER Classification System

More...
PANTHERi
PTHR13715:SF15 PTHR13715:SF15, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08709 Ins145_P3_rec, 1 hit
PF02815 MIR, 1 hit
PF08454 RIH_assoc, 1 hit
PF01365 RYDR_ITPR, 2 hits
PF02026 RyR, 4 hits
PF00622 SPRY, 3 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00795 RYANODINER

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00472 MIR, 4 hits
SM00449 SPRY, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF100909 SSF100909, 2 hits
SSF47473 SSF47473, 1 hit
SSF49899 SSF49899, 3 hits
SSF82109 SSF82109, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50188 B302_SPRY, 3 hits
PS50919 MIR, 5 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

A0A3P4LUK8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
GGRRLPPSSV QHANPPLSSI YLPGAPEVSD PSPSGLDIMG DGGEGEDEVQ
60 70 80 90 100
FLRTDDEVVL QCSATVLKEQ LKLCLAAEGF GNRLCFLEPT SNAQNVPPDL
110 120 130 140 150
AICCFVLEQS LSVRALQEML ANTVEAGVES SQGGGHRTLL YGHAILLRHT
160 170 180 190 200
HSGMYLSCLT TSRSMTDKLA FDVGLQEDAT GEACWWTMHP ASKQRSEGEK
210 220 230 240 250
VRVGDDLILV SVSSERYLHL STASGELQVD ASFMQTLWNM NPICSGCEEG
260 270 280 290 300
YVTGGHVLRL FHGHMDECLT ISPADSEDQR RLVHYEGGAV CTHARSLWRL
310 320 330 340 350
EPLRISWSGS HLRWGQPLRI RHVTTGRYLA LTEDQGLVVV DASKAHTKAT
360 370 380 390 400
SFCFRISKEK LDMAPKRDVD GMGPPEIKYG ESLCFVQHVA SGLWLTYAAP
410 420 430 440 450
DPKALRLGVL KKKAMLHQEG HMDDALSLTR CQQEESQAAR MIYSTAGLYN
460 470 480 490 500
QFIKGLDSFS GKPRGSGPPA GTALPIEGVI LSLQDLIGYF EPPSEELQHE
510 520 530 540 550
EKQSKLRSLR NRQSLFQEEG MLSLVLNCID RLNVYTTAAH FAEFAGEEAA
560 570 580 590 600
ESWKEIVNLL YELLASLIRG NRTNCALFST NLDWLVSKLD RLEASSGILE
610 620 630 640 650
VLYCVLIESP EVLNIIQENH IKSIISLLDK HGRNHKVLDV LCSLCVCNGV
660 670 680 690 700
AVRSNQDLIT ENLLPGRELL LQTNLINYVT SIRPNIFVGR AEGTTQYGKW
710 720 730 740 750
YFEVMVDEVA PFLTAQATHL RVGWALTEGY SPYPGGGEGW GGNGVGDDLY
760 770 780 790 800
SYGFDGLHLW TGHVARPVTS PGQHLLAPED VVSCCLDLSV PSISFRINGC
810 820 830 840 850
PVQGVFEAFN LDGLFFPVVS FSAGVKVRFL LGGRHGEFKF LPPPGYAPCH
860 870 880 890 900
EAVLPRERLH LEPIKEYRRE GPRGPHLVGP SRCLSHTDFV PCPVDTVQIV
910 920 930 940 950
LPPHLERIRE KLAENIHELW ALTRIEQGWT YGPVRDDNKR LHPCLVDFHS
960 970 980 990 1000
LPEPERNYNL QMSGETLKTL LALGCHVGMA DEKAEDNLKK TKLPKTYMMS
1010 1020 1030 1040 1050
NGYKPAPLDL SHVRLTPAQM TLVDRLAENG HNVWARDRVA QGWSYSAVQD
1060 1070 1080 1090 1100
IPARRNPRLV PYRLLDEATK RSNRDSLCQA VRTLLGYGYN IEPPDQEPSQ
1110 1120 1130 1140 1150
VESQSRWDRV RIFRAEKSYT VQSGRWYFEF EAVTTGEMRV GWARPDLRPD
1160 1170 1180 1190 1200
VELGADELAY VFNGHRGQRW HLGSEPFGRP WQPGDVVGCM IDLTENTIIF
1210 1220 1230 1240 1250
TLNGEVLMSD SGSETAFREI EIGDGFLPVC SLGPGQVGHL NLGQDVSSLR
1260 1270 1280 1290 1300
FFAICGLQEG FEPFAINMQR PVTTWFSKSL PQFEAVPLEH PHYEVARVDG
1310 1320 1330 1340 1350
TVDTPPCLRL SHRTWGSQNS LVEMVFLRLS LPVQFHQHFR CTAGATPLAH
1360 1370 1380 1390 1400
PGLQPPAEDE ARAAEPDPDY ENLRRSAGRW GEAEGGKEGN AKEGAPGGNA
1410 1420 1430 1440 1450
QAGVEAQPIR VENEKDATTE KNKKRGFLFK AKKVAMMTQP PATPTLPRLP
1460 1470 1480 1490 1500
REVVPADNRD DPEIILNTTT YYYSVRVFAG QEPSCVWVGW VTPDYHQHDM
1510 1520 1530 1540 1550
NFELSKVRAV TVTMGDEQGN VHSSLKCSNC YMVWGGDFVS SGQQGRISHT
1560 1570 1580 1590 1600
DLVIGCLVDL ATGLMTFTAN GKESNTFFQV EPNTKLFPAV FVLPTHQNVI
1610 1620 1630 1640 1650
QFELGKQKNI MPLSAAMFLS ERKNPAPQCP PRLEVQMLMP VSWSRMPNHF
1660 1670 1680 1690 1700
LQVETRRAGE RLGWAVQCQE PLTMMALHIP EENRSMDILE LSERLDLQRF
1710 1720 1730 1740 1750
HSHTLRLYRA VCALGNNRVA HALCSHVDQA QLLHALEDAH LPGPLRAGYY
1760 1770 1780 1790 1800
DLLISIHLES ACRSRRSMLS EYIVPLTEET RAITLFPPGR SAEDGPRRHG
1810 1820 1830 1840 1850
LPGVGVTTSL RPPHHFSPPC FVAALPAAGV AEAPARLSPS IPLEALRDKA
1860 1870 1880 1890 1900
LRMLGEAVRD GGQHARDPVG GSVEFQFVPV LKLVSTLLVM GIFADEDVKQ
1910 1920 1930 1940 1950
ILKMIEPEVF TEEEEEEEEE EEEEDEEEKE EDEEEEAQEK EDEEKEEEET
1960 1970 1980 1990 2000
AEGEKEEGLE EGLLQMKLPE SVKLQMCHLL EYFCDQELQH RVESLAAFAE
2010 2020 2030 2040 2050
RYVDKLQANQ RDRYGLLMKA FTMSAAETAR RTREFRSPPQ EQINMLLHFK
2060 2070 2080 2090 2100
DGEDEEECPL PEEVRQDLLE FHQDLLAHCG IQLEGEEEEP EEEATLGSRL
2110 2120 2130 2140 2150
MSLLEKVRLV KKKEEKPEEE PPAEESKPQS LQELVSHTVV RWAQEDFVQS
2160 2170 2180 2190 2200
PELVRAMFSL LHRQYDGLGE LLRALPRAYT ISPSSVEDTM SLLECLGQIR
2210 2220 2230 2240 2250
SLLIVQMGPQ EENLMIQSIG NIMNNKVFYQ HPNLMRALGM HETVMEVMVN
2260 2270 2280 2290 2300
VLGGGGESKE IRFPKMVTSC CRFLCYFCRI SRQNQRSMFD HLSYLLENSG
2310 2320 2330 2340 2350
IGLGMQGSTP LDVAAASVID NNELALALQE QDLEKVVSYL AGCGLQSCPM
2360 2370 2380 2390 2400
LLAKGYPDIG WNPCGGERYL DFLRFAVFVN GESVEENANV VVRLLIRKPE
2410 2420 2430 2440 2450
CFGPALRGEG GSGLLAAIEE AIRISEDPAR DGPGVRRDRR REHFGEEPPE
2460 2470 2480 2490 2500
ENRVHLGHAI MSFYAALIDL LGRCAPEMHL IQAGKGEALR IRAILRSLVP
2510 2520 2530 2540 2550
LDDLVGIISL PLQIPTLGKD GALVQPKMSA SFVPDHKASM VLFLDRVYGI
2560 2570 2580 2590 2600
ENQDFLLHVL DVGFLPDMRA AASLDTATFS TTEMALALNR YLCLAVLPLI
2610 2620 2630 2640 2650
TKCAPLFAGT EHRAIMVDSM LHTVYRLSRG RSLTKAQRDV IEDCLMSLCR
2660 2670 2680 2690 2700
YIRPSMLQHL LRRLVFDVPI LNEFAKMPLK LLTNHYERCW KYYCLPTGWA
2710 2720 2730 2740 2750
NFGVTSEEEL HLTRKLFWGI FDSLAHKKYD AELYRMAMPC LCAIAGALPP
2760 2770 2780 2790 2800
DYVDASYSSK AEKKATVDAE GNFDPRPVET LNVIIPEKLD SFINKFAEYT
2810 2820 2830 2840 2850
HEKWAFDKIQ NNWSYGENID EELKTHPMLR PYKTFSEKDK EIYRWPIKES
2860 2870 2880 2890 2900
LKAMIAWEWT IEKAREGEEE KTEKKKTRKI SQSAQTYDPR EGYSPQPPDL
2910 2920 2930 2940 2950
SGVTLSRELQ AMAEQLAENY HNTWGRKKKQ ELEAKGGGTH PLLVPYDTLT
2960 2970 2980 2990 3000
AKEKARDREK AQELLKFLQM NGYAVTRGLK DMELDTSSIE KRFAFGFLQQ
3010 3020 3030 3040 3050
LLRWMDISQE FIAHLEAVVS SGRVEKSPHE QEIKFFAKIL LPLINQYFTN
3060 3070 3080 3090 3100
HCLYFLSTPA KVLGSGGHAS NKEKEMITSL FCKLAALVRH RVSLFGTDAP
3110 3120 3130 3140 3150
AVVNCLHILA RSLDARTVMK SGPEIVKAGL RSFFESASED IEKMVENLRL
3160 3170 3180 3190 3200
GKVSQARTQV KGVGQNLTYT TVALLPVLTT LFQHIAQHQF GDDVILDDVQ
3210 3220 3230 3240 3250
VSCYRTLCSI YSLGTTKNTY VEKLRPALGE CLARLAAAMP VAFLEPQLNE
3260 3270 3280 3290 3300
YNACSVYTTK SPRERAILGL PNSVEEMCPD IPVLERLMAD IGGLAESGAR
3310 3320 3330 3340 3350
YTEMPHVIEI TLPMLCSYLP RWWERGPEAP PPALPAGAPP PCTAVTSDHL
3360 3370 3380 3390 3400
NSLLGNILRI IVNNLGIDEA SWMKRLAVFA QPIVSRARPE LLHSHFIPTI
3410 3420 3430 3440 3450
GRLRKRAGKV VAEEEQLRLE AKAEAEEGEL LVRDEFSVLC RDLYALYPLL
3460 3470 3480 3490 3500
IRYVDNNRAH WLTEPNPSAE ELFRMVGEIF IYWSKSHNFK REEQNFVVQN
3510 3520 3530 3540 3550
EINNMSFLTA DNKSKMAKAG DVQSGGSDQE RTKKKRRGDR YSVQTSLIVA
3560 3570 3580 3590 3600
TLKKMLPIGL NMCAPTDQEL ITQAKNRYAL KDTDEEVREY LQNNLHLQGK
3610 3620 3630 3640 3650
VEGSPSLRWQ MALYRGVPGR EEDADDPEKI VRRVQEVSAV LYHLEQIEHP
3660 3670 3680 3690 3700
YKSKKAVWHK LLSKQRRRAV VACFRMTPLY NLPTHRACNM FLESYKAAWI
3710 3720 3730 3740 3750
LTEDHSFEDR MIDDLSKAGE QEEEEEEVEE KKPDPLHQLV LHFSRTALTE
3760 3770 3780 3790 3800
KSKLDEDYLY MAYADIMAKS CHLEEGGENG EADEEEVEVS FEEKEMEKQR
3810 3820 3830 3840 3850
LLYQQARLHN RGAAEMVLQM ISACKGETGA MVSSTLKLGI SILNGGNADV
3860 3870 3880 3890 3900
QQKMLDYLKD KKEVGFFQSI QALMQTCSVL DLNAFERQNK AEGLGMVNED
3910 3920 3930 3940 3950
GTVINRQNGE KVMADDEFTQ DLFRFLQLLC EGHNNDFQNY LRTQTGNTTT
3960 3970 3980 3990 4000
INIIICTVDY LLRLQESISD FYWYYSGKDV IEEQGKRNFS KAMSVAKQVF
4010 4020 4030 4040 4050
NSLTEYIQGP CTGNQQSLAH SRLWDAVVGF LHVFAHMMMK LAQDSSQIEL
4060 4070 4080 4090 4100
LKELLDLQKD MVVMLLSLLE GNVVNGMIAR QMVDMLVESS SNVEMILKFF
4110 4120 4130 4140 4150
DMFLKLKDIV GSEAFQDYVT DPRGLISKKD FQKAMDSQKQ FTGPEIQFLL
4160 4170 4180 4190 4200
SCSEADENEM INCEEFANRF QEPARDIGFN VAVLLTNLSE HVPHDPRLRT
4210 4220 4230 4240 4250
FLELAESILE YFRPYLGRIE IMGASRRIER IYFEISETNR TQWEMPQVKE
4260 4270 4280 4290 4300
SKRQFIFDVV NEGGESEKME LFVSFCEDTI FEMQIAAQIS EPEGEPEEDE

DDGAA
Length:4,305
Mass (Da):484,793
Last modified:February 13, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9A8674F7FBFC7677
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1
Non-terminal residuei4305Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CYRY02001880 Genomic DNA Translation: VCW66537.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CYRY02001880 Genomic DNA Translation: VCW66537.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

CDDicd12877 SPRY1_RyR, 1 hit
cd12878 SPRY2_RyR, 1 hit
cd12879 SPRY3_RyR, 1 hit
InterProiView protein in InterPro
IPR001870 B30.2/SPRY
IPR013320 ConA-like_dom_sf
IPR011992 EF-hand-dom_pair
IPR014821 Ins145_P3_rcpt
IPR036300 MIR_dom_sf
IPR016093 MIR_motif
IPR013662 RIH_assoc-dom
IPR000699 RIH_dom
IPR013333 Ryan_recept
IPR003032 Ryanodine_rcpt
IPR035910 RyR/IP3R_RIH_dom_sf
IPR033215 RyR1
IPR035761 SPRY1_RyR
IPR035764 SPRY2_RyR
IPR035762 SPRY3_RyR
IPR003877 SPRY_dom
PANTHERiPTHR13715:SF15 PTHR13715:SF15, 1 hit
PfamiView protein in Pfam
PF08709 Ins145_P3_rec, 1 hit
PF02815 MIR, 1 hit
PF08454 RIH_assoc, 1 hit
PF01365 RYDR_ITPR, 2 hits
PF02026 RyR, 4 hits
PF00622 SPRY, 3 hits
PRINTSiPR00795 RYANODINER
SMARTiView protein in SMART
SM00472 MIR, 4 hits
SM00449 SPRY, 3 hits
SUPFAMiSSF100909 SSF100909, 2 hits
SSF47473 SSF47473, 1 hit
SSF49899 SSF49899, 3 hits
SSF82109 SSF82109, 2 hits
PROSITEiView protein in PROSITE
PS50188 B302_SPRY, 3 hits
PS50919 MIR, 5 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A3P4LUK8_GULGU
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A3P4LUK8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 13, 2019
Last sequence update: February 13, 2019
Last modified: October 16, 2019
This is version 7 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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