Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 5 (31 Jul 2019)
Sequence version 1 (10 Apr 2019)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein
Submitted name:

Myelin transcription factor 1 like

Gene

MYT1L

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Myelin transcription factor 1 likeImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MYT1LImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEquus caballus (Horse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9796 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002281 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:20529 MYT1L

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini597 – 845MYT1InterPro annotationAdd BLAST249

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 168DisorderedSequence analysisAdd BLAST168
Regioni213 – 240DisorderedSequence analysisAdd BLAST28
Regioni320 – 347DisorderedSequence analysisAdd BLAST28
Regioni365 – 396DisorderedSequence analysisAdd BLAST32
Regioni425 – 487DisorderedSequence analysisAdd BLAST63
Regioni652 – 684DisorderedSequence analysisAdd BLAST33

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1031 – 1100Sequence analysisAdd BLAST70

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi82 – 162AcidicSequence analysisAdd BLAST81
Compositional biasi320 – 334PolarSequence analysisAdd BLAST15
Compositional biasi375 – 396PolyampholyteSequence analysisAdd BLAST22
Compositional biasi425 – 483PolyampholyteSequence analysisAdd BLAST59
Compositional biasi658 – 684PolarSequence analysisAdd BLAST27

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155671

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013681 Myelin_TF
IPR002515 Znf_C2H2C
IPR036060 Znf_C2H2C_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08474 MYT1, 1 hit
PF01530 zf-C2HC, 6 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103637 SSF103637, 6 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51802 ZF_CCHHC, 6 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

A0A3Q2LHC7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEVDAEEKRH RTRSKGVRGT STCPTPGCDG SGHVSGKYAR HRSVYGCPLA
60 70 80 90 100
KKRKTQDKQP QEPAPKRKPF AVKADSSSVD ECYESDGTEE DMDEKEEDEE
110 120 130 140 150
EEYSEDDDEQ RDDDDEEEEV DREEEEEIEE EDDDDDEDGE DVDEEEEEEE
160 170 180 190 200
EEEEEEEEEE NEDHQMNCHN TRIMQDAEKD DNNNDEYDNY DELVAKSLLN
210 220 230 240 250
LGKIAEDAAY RARTESEMNS NTSNSLEDDS DKNENLGRKS ELSLDLDSDV
260 270 280 290 300
VRETVDSLKL LAQGHGVVLA ENMNERNYAD TMSQQDNRNM NYESDEEVCL
310 320 330 340 350
SSLECLRNQC FDLARKLSET NPQERNQQQN MNIRQHVRQE DDFPGRTPDR
360 370 380 390 400
NYSDMMNLMR LEEQLSPRSR TFSSCAKEDG YHERDDDTTS VNSDRSEEVF
410 420 430 440 450
DMTKGNLTLL EKAIALETER AKAMREKMAM EAGRRDNMRS YEEQSPRQLP
460 470 480 490 500
GEERKPKSSD SHVKKPYYGK DPSRAEKKES KCPTPGCDGT GHVTGLYPHH
510 520 530 540 550
RSLSGCPHKD RVPPEILAMH ENVLKCPTPG CTGRGHVNSN RNSHRSLSGC
560 570 580 590 600
PIAAAEKLAK AQEKHQSCDV SKSNQASDRV LRPMCFVKQL EIPHYGYRNN
610 620 630 640 650
VPTTTPRSNL AKELEKYSKT SFEYNSYDSH TYGKRAIAPK VQTRDISPKG
660 670 680 690 700
YDAKRYCKNA SPSSSTTSSY APSSSSNLSC GGGSSASSTC SKSSFDYTHD
710 720 730 740 750
MEAAHMAATA ILNLSTRCRE MPQNLSTKPQ DLCTNPDMEV DENGTLDLSM
760 770 780 790 800
NKQRPREGCC PILTPLEPMS PQQQAVMNSR CFQLSEGDCW DLPVDYTKMK
810 820 830 840 850
PRRIDEDDPK EITPEDLDPF QEALEERRYP GEVTIPSPKP KYPQCKESKK
860 870 880 890 900
DLITLSGCPL ADKSIRSMLA TSSQELKCPT PGCDGSGHIT GNYASHRSLS
910 920 930 940 950
GCPRAKKSGI RIAQSKEDKE DQEPIRCPVP GCDGQGHITG KYASHRSASG
960 970 980 990 1000
CPLAAKRQKD GYLNGSQFSW KSVKTEGMSC PTPGCDGSGH VSGSFLTHRS
1010 1020 1030 1040 1050
LSGCPRATSA MKKAKLSGEQ MLTIRQRASN GIENDEEIKQ LDEEIKELNE
1060 1070 1080 1090 1100
SNSQMEADMI KLRTQITTME SNLKTIEEEN KVIEQQNESL LHELANLSQS
1110 1120 1130 1140 1150
LIHSLANIQL PHMVNFGCLW LPPQNHNDPI NEQNFDAYVT TLTDMYTNQD
1160 1170
RYQSPENKAL LENIKQAVRG IQV
Length:1,173
Mass (Da):132,018
Last modified:April 10, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i46999FFAD47976A0
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A3Q2H8X7A0A3Q2H8X7_HORSE
Myelin transcription factor 1 like
MYT1L
1,276Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HS26A0A3Q2HS26_HORSE
Myelin transcription factor 1 like
MYT1L
1,253Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2I8E3A0A3Q2I8E3_HORSE
Myelin transcription factor 1 like
MYT1L
1,199Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F7C9X0F7C9X0_HORSE
Myelin transcription factor 1 like
MYT1L
1,138Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2H1L0A0A3Q2H1L0_HORSE
Myelin transcription factor 1 like
MYT1L
973Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HM17A0A3Q2HM17_HORSE
Myelin transcription factor 1 like
MYT1L
963Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2KNM3A0A3Q2KNM3_HORSE
Myelin transcription factor 1 like
MYT1L
1,018Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSECAT00000034139; ENSECAP00000040340; ENSECAG00000014657

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENSECAT00000034139; ENSECAP00000040340; ENSECAG00000014657

Organism-specific databases

VGNCiVGNC:20529 MYT1L

Phylogenomic databases

GeneTreeiENSGT00940000155671

Family and domain databases

InterProiView protein in InterPro
IPR013681 Myelin_TF
IPR002515 Znf_C2H2C
IPR036060 Znf_C2H2C_sf
PfamiView protein in Pfam
PF08474 MYT1, 1 hit
PF01530 zf-C2HC, 6 hits
SUPFAMiSSF103637 SSF103637, 6 hits
PROSITEiView protein in PROSITE
PS51802 ZF_CCHHC, 6 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A3Q2LHC7_HORSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A3Q2LHC7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 10, 2019
Last sequence update: April 10, 2019
Last modified: July 31, 2019
This is version 5 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again