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Entry version 42 (31 Jul 2019)
Sequence version 1 (05 Apr 2011)
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Protein
Submitted name:

Polyketide synthase

Gene

fkbA

Organism
Streptomyces kanamyceticus
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Polyketide synthaseImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:fkbAImported
ORF Names:Tcs_SK_034Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiStreptomyces kanamyceticusImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1967 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1848O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei3413O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei5328O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei6316O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

PhosphopantetheinePROSITE-ProRule annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1813 – 1888CarrierInterPro annotationAdd BLAST76
Domaini3378 – 3453CarrierInterPro annotationAdd BLAST76
Domaini5293 – 5368CarrierInterPro annotationAdd BLAST76
Domaini6281 – 6356CarrierInterPro annotationAdd BLAST76

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni2987 – 3015DisorderedSequence analysisAdd BLAST29
Regioni3091 – 3117DisorderedSequence analysisAdd BLAST27
Regioni4401 – 4425DisorderedSequence analysisAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi3091 – 3110PolarSequence analysisAdd BLAST20

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1200.10, 4 hits
3.10.129.110, 3 hits
3.40.366.10, 4 hits
3.40.47.10, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001227 Ac_transferase_dom_sf
IPR036736 ACP-like_sf
IPR014043 Acyl_transferase
IPR016035 Acyl_Trfase/lysoPLipase
IPR013154 ADH_N
IPR011032 GroES-like_sf
IPR032821 KAsynt_C_assoc
IPR018201 Ketoacyl_synth_AS
IPR014031 Ketoacyl_synth_C
IPR014030 Ketoacyl_synth_N
IPR016036 Malonyl_transacylase_ACP-bd
IPR036291 NAD(P)-bd_dom_sf
IPR020801 PKS_acyl_transferase
IPR020841 PKS_Beta-ketoAc_synthase_dom
IPR020807 PKS_dehydratase
IPR042104 PKS_dehydratase_sf
IPR020843 PKS_ER
IPR013968 PKS_KR
IPR020806 PKS_PP-bd
IPR015083 Polyketide_synth_docking
IPR009081 PP-bd_ACP
IPR006162 Ppantetheine_attach_site
IPR016039 Thiolase-like

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00698 Acyl_transf_1, 4 hits
PF08240 ADH_N, 2 hits
PF08990 Docking, 1 hit
PF16197 KAsynt_C_assoc, 4 hits
PF00109 ketoacyl-synt, 4 hits
PF02801 Ketoacyl-synt_C, 4 hits
PF08659 KR, 3 hits
PF00550 PP-binding, 4 hits
PF14765 PS-DH, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00827 PKS_AT, 4 hits
SM00826 PKS_DH, 3 hits
SM00829 PKS_ER, 2 hits
SM00825 PKS_KS, 4 hits
SM00823 PKS_PP, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47336 SSF47336, 4 hits
SSF50129 SSF50129, 2 hits
SSF51735 SSF51735, 8 hits
SSF52151 SSF52151, 4 hits
SSF53901 SSF53901, 4 hits
SSF55048 SSF55048, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00606 B_KETOACYL_SYNTHASE, 4 hits
PS50075 CARRIER, 4 hits
PS00012 PHOSPHOPANTETHEINE, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

E9KTB8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPEQDKTVEY LRWATTELQR TRAELAAHSE PLAIVGMACR LPGGVASPDD
60 70 80 90 100
LWRLLESGGD GIGAFPGDRG WETGADGRGG FLSGAAGFDA AFFGVSPREA
110 120 130 140 150
LAMDPQQRVV LETSWEALEH AGIDPHTLNG SDTGVFLGAF FQGYGIGADF
160 170 180 190 200
DGYGTTSIHT SVLSGRLSYF YGLEGPAVTV DTACSSSLVA LHQAGQSLRT
210 220 230 240 250
GECSLALVGG VTVMASPAGF ADFSEQGGLA PDGRCKAFAE AADGTAFSEG
260 270 280 290 300
SGVLVVERLS DAERHGHRIL AVVRGSAVNQ DGASNGLSAP NGPSQERVIR
310 320 330 340 350
QALANAGLQP SDVDAVEAHG TGTRLGDPIE ATALLATYGQ HRTTPLLLGS
360 370 380 390 400
LKSNIGHTQA AAGVAGIIKM VLAMHHDTLP PTLHVDTPSS HVDWTTGGVE
410 420 430 440 450
LLTDARPWPT TTGPRRAGIS SFGVSGTNAH VILESPTPVP SPGAEPGARP
460 470 480 490 500
VPLPISARTP EALDEHTIRI RAFLDDNPGA DHVAVAQTLA RRTPFEHRAV
510 520 530 540 550
LLGDTLITAD PNAGSGPVVF VYSGQSTLHP HTGRQLAATY PVFADAWGEV
560 570 580 590 600
LGHLDADQGP ATHFAHQIAL TALLRSWGIA PHAVIGHSLG EISAACAAGV
610 620 630 640 650
LSLGDASALL AARSRLMDEL PAGGAMVTVL TSEENALRAL RPGVEIAAVN
660 670 680 690 700
GPHSVVLSGD EGPVLAVAQQ LGIHHRLPTR HAGHSARMDP LVAPLLEAAS
710 720 730 740 750
GLTYHQPRIA IPGDPTTAAY WARQVRDQVR FQAHAERYPG ATFLEIGPNQ
760 770 780 790 800
DLSPVVDGIP TQTGTPDEVQ ALHTALARLH TRGGVVDWPT VLGGDRAPVA
810 820 830 840 850
LPTYPFQHKD YWLRATAQAD VTGAGQEQVA HPLLGAAVAL PGTGGTVLTG
860 870 880 890 900
RVSLASHPWL GGHAVNGTVL LPGAAFLELA VRAGDEAGCD LLHELVVETP
910 920 930 940 950
LTLPATGSVA ISVEVAEPDD TGRRAVTVHA RADGAVLWTR HATGFLGKAA
960 970 980 990 1000
ATTAETGDPA PWPPAGARPV DVGDVYERFG SIGYAYGSAF QGLRAAWRDG
1010 1020 1030 1040 1050
DTVHAEVALP DEQGPDAARF TLHPALLDAA FQAGALSALD APGEAALLPF
1060 1070 1080 1090 1100
SFQDVRIHAA GATRARVTVS RDGDRSTVRM TGEDGQPVAE VGSVVSRPYA
1110 1120 1130 1140 1150
GGSGSDDELL RPVWTELPMP APSAADPRVE VLGADPLDGE PAAATRELTA
1160 1170 1180 1190 1200
RVLDALQHRL SATDDVTLVV RIGTGLAAAA TAGLVRSAQA ENPGRIVLVE
1210 1220 1230 1240 1250
ASPDTPADLL TACAALDEPQ LAVRDGVLFA PRLVRMSDPV HGPLPLPDGD
1260 1270 1280 1290 1300
WLLTHSASGV LHDVTLAVDG TPRRALEAGE VRVDVRAAGL NFRDVLIALG
1310 1320 1330 1340 1350
TYDGATALGG EAAGIVVETG PGVADLAPGD RVFGLTRGGI GPTAVTDRRW
1360 1370 1380 1390 1400
LARIPDGWSF TTAASVPIVF ATAWYGLVDL AGLRAGEKVL VHAATGGVGM
1410 1420 1430 1440 1450
AATQLARHLG AEVYATAGTG KQHVLRAAGL PGTHIADSRT TAFRTDFPRM
1460 1470 1480 1490 1500
DVVLNSLTGE FIDASLELLD AEGRFVEMGR AELRDPDTIT PAYLPFDLMD
1510 1520 1530 1540 1550
AGTDRIGEIL GELLQLFDAG ALTPLPVRAW DVRQARDALG VMSRARHIGK
1560 1570 1580 1590 1600
NVLTLPRPLD PEGAIVITGG SGTLAGILAR HVSGQHVYLL SRTAPPEGTP
1610 1620 1630 1640 1650
GIHLPCDVGD RQQLAAALRR IDRPITAVVH TAGALDDGTL PSLTPERFDT
1660 1670 1680 1690 1700
VLRPKADGAW HLHELTKDQD LAAFVLYSSA AGVLGNAGQG NYVAANAFLD
1710 1720 1730 1740 1750
ALAEQRQAAG LPALSIAWGL WEDTSGLTAE LSEADRQRMR RSGFRTISAR
1760 1770 1780 1790 1800
QGMRLYEAAR RTGSPVVVAA ALDDAPDVPL LRGLRRTTVR RATVRERSLS
1810 1820 1830 1840 1850
DELAVLPDDE RADALLAFVR NSTATVLGHL GAEDIPATAT FKELGIDSLT
1860 1870 1880 1890 1900
AVQLRNALTT ATGVRLNATA VFDFPTPRAL AARLGDELAG TRAPVAARTA
1910 1920 1930 1940 1950
ATAAAHDEPL AIVGMACRLP GGVASPEGLW RLVASGTDAI TEFPADRGWD
1960 1970 1980 1990 2000
VDALYDPDPD AIGKTFVRHG GFLDGATGFD AGFFGISPRE ALAMDPQQRV
2010 2020 2030 2040 2050
LLETSWEAFE SAGITPDSAR GSDTGVFIGA FSYGYGTGAD TNGFGATGSQ
2060 2070 2080 2090 2100
TSVLSGRLSY FYGLEGPSVT VDTACSSSLV ALHQAGQSLR SGECSLALVG
2110 2120 2130 2140 2150
GVTVMASPGG FVEFSRQRGL APDGRAKAFG AGADGTSFAE GAGALVVERL
2160 2170 2180 2190 2200
SDAERHGHTV LAVVRGSAVN SDGASNGLSA PNGPSQERVI RQALANAKLT
2210 2220 2230 2240 2250
PADVDAVEAH GTGTRLGDPI EAQALLATYG QDRATPLLLG SLKSNIGHAQ
2260 2270 2280 2290 2300
AASGVAGIIK MVQAIRHGEL PPTLHADEPS PHVDWTAGAV ELLTSARPWP
2310 2320 2330 2340 2350
GTGRPRRAAV SSFGVSGTNA HIILEAGPVK AGPVEAGPVP AAPPSAPGED
2360 2370 2380 2390 2400
LPLLVSARSP EALDEQIGRL RTYLDTRPGV DRAAVAQTLA RRTHFAHRAV
2410 2420 2430 2440 2450
LLGDTVITTS PSHQADELVF VYSGQGTQHP AMGEQLAAAF PVFAETWHDA
2460 2470 2480 2490 2500
LRRLDDPDPH DPTRSQHTLF AHQAALTALL RSWDITPHAV IGHSLGEITA
2510 2520 2530 2540 2550
AYAAGILSLD DACTLITTRA RLMHTLPPPG AMVTVLTGEE EARQALRPGV
2560 2570 2580 2590 2600
EIAAVNGAHS VVLSGDEDAV LDVAQRLGIH HRLPAPHAGH SAHMEPVAAE
2610 2620 2630 2640 2650
LLATTRRLRY DRPHTAIPND PTTAEYWAEQ VRNPVLFHAH TQQYPDAVFV
2660 2670 2680 2690 2700
EIGPGQDLSP LVDGIALQNG PANEAHALRT ALARLFSRGA TLDWPLVLGG
2710 2720 2730 2740 2750
ASRHDPDVPS YAFQQRPYWI ESAPPATADA GHPVLGTGVA VAGSPGRVFT
2760 2770 2780 2790 2800
GPVPTGADRA VFIAELALAA ADATDCATVE QLDITSVPGG SARGRAIAQT
2810 2820 2830 2840 2850
WVDEPAADGR RRFTVHSRVG DAPWTLHAEG VLRPGGVPRP DAVDAAWPPP
2860 2870 2880 2890 2900
GAVPADGLSR AWRRADQVFV EAEVDSPDGF VAHPDLLDAV FSAVGDGSRQ
2910 2920 2930 2940 2950
PTGWRDLAVH ASDATVLRAC LTRRAGGVVE LAAFDGAGLP VLTAESVTLG
2960 2970 2980 2990 3000
EVASAGGSDE SDGLLRLEWL PVAEAHYDGA DSLPEGYTLI TATHPDDPED
3010 3020 3030 3040 3050
DPTNPHSTPT RTHTQTTRVL AALQHHLTTT NHTLIIHTTT DPPGAAVTGL
3060 3070 3080 3090 3100
TRTAQNEHPG RIHLIETHHP HTPLPLTQLT TLNQPHLRLT NNTLHTPHLT
3110 3120 3130 3140 3150
PLTSTGNPNP HHPTTPTPPL NPDHAILITG GSGTLAGILA RHLNHPHTYL
3160 3170 3180 3190 3200
LSRTPPPPTT PGTHIPCDLT DPTQITHALN QIPQPLTGIF HTAATLDDTP
3210 3220 3230 3240 3250
LHTLTPQRLT TVLQPKADAA WHLHHHTQNQ PLTHFVLYSS AAATLGSPGQ
3260 3270 3280 3290 3300
ANYAAANAFL DALATHRHTH NQPATTIAWG MWHTTTTLTA HLTDSDRDRI
3310 3320 3330 3340 3350
RRGGFLPISD DEGMRLYDAA VGSGEDYVLA ASMDPAQPMS GDVPPILSGL
3360 3370 3380 3390 3400
RRSARRTART GQTFAQRLAE LPDADRDTAL STLVMDATAA VLGHADASEI
3410 3420 3430 3440 3450
GPTTTFKDLG IDSLTAIELR NRLAEATGLR LSATMVFDHP TPRVLAAKLR
3460 3470 3480 3490 3500
TDLFGTAVPT PTRTTRARHD EPLAIVGMAC RLPGGVTSPE DLWRLVASGT
3510 3520 3530 3540 3550
DAITEFPTDR GWDIDRMFDP DPDAPGKTYV RHGGFLSEAA GFDAAFFGIS
3560 3570 3580 3590 3600
PREAWAMDPQ QRVILETVWE AFENAGIVPD TLRGSDTGVF MGAFSHGYGA
3610 3620 3630 3640 3650
GVDLGGFGAT ATQNSVLSGR LSYFFGMEGP AVTIDTACSS SMVALHQAAQ
3660 3670 3680 3690 3700
SLRDGECSLA LAGGVTVMPT PLGYVEFCRQ RGLAPNGRAK AFAEGADGTS
3710 3720 3730 3740 3750
FSEGAGVLVV ERLSDAERNG HTVLALVRSS AVNQDGASNG ISAPNGPSQQ
3760 3770 3780 3790 3800
RVIRQALDKA GLTPADVDVV EAHGTGTPLG DPIEAQAIIA TYGQDRDTPL
3810 3820 3830 3840 3850
YLGSVKSNIG HTQTTAGLAG VIKMVMAMRH GLLPKTLHVD EPSSHVDWSA
3860 3870 3880 3890 3900
GAVELLTEAR PWPDSDRPRR AGVSSLGISG TNAHVILEGV AESSVRSGGS
3910 3920 3930 3940 3950
SGLVPLPVSA RTESSLALQV ERVGEYVRGG ADLGAVADGL VRGRAVFDRR
3960 3970 3980 3990 4000
AVLLGESTVA GVAVEGARTV FVFPGQGSQW VGMGRELMGA SEVFAARMRE
4010 4020 4030 4040 4050
CAAALEPHTG WDVLDVLGEA VVADRVEVLQ PASWAVAVSL AALWQAHGVV
4060 4070 4080 4090 4100
PDAVIGHSQG EIAAACVAGA LSLEDAARVV ALRSQTIAAR LAGHGAMASI
4110 4120 4130 4140 4150
ALPASAVEVA EGVWIAARNG PESTVVAGDP GAVERVLARY EAAGVRVRRI
4160 4170 4180 4190 4200
AVDYASHTPH VEAIEEQLAD VLGGITSSAP DISWWSTVDS GWVTEPVGDD
4210 4220 4230 4240 4250
YWYRNLRQPV AMDTAISELD GSLFIECSAH PVLLPALDQE HTVASLRTDD
4260 4270 4280 4290 4300
GDWDRFLTAL AQAWTQGAPV DWTTLIEPAP HRLLDLPTYP FDHKRYWIEA
4310 4320 4330 4340 4350
ASATDLTALG LTDTAHPMLA ATAALPTNDG TVLTGRISLR THPWLADHAI
4360 4370 4380 4390 4400
QDSVLLPGTA FLELVVRAGD EVGCDTIDEL VIETPLVLPV TGAVDLTVTV
4410 4420 4430 4440 4450
DQPDTTGHRP VSVHARPEGT DTWTRHATGT LTTSATDTTP APSSFPQWPP
4460 4470 4480 4490 4500
TSASAIDITE FYAQLAVLGY RFGPTFRGLR AAWRDGDTVY AEVALPEDRA
4510 4520 4530 4540 4550
ADADRFGVHP ALLDAALQSG SLLMLASDGE QGVQLPFSWH GVRFHATGAT
4560 4570 4580 4590 4600
SLRVTIVPGP DGLRLRAADS ENHPVATIDA LVTRPPADLA PADPVLRVGW
4610 4620 4630 4640 4650
TAVPVPAEVS PSDADVLTLH SDDADPVQET RELTTRVLDA LLEVERTLIV
4660 4670 4680 4690 4700
QVTGGLAAMA AAGLVRTAQS EQPGRFFLVE TDPGEVLDSA RCDTIAALGE
4710 4720 4730 4740 4750
PRLRLRDNRF EAARLVRATP ALTPPDTGSW QLRQSATGSL DDLALVPTDE
4760 4770 4780 4790 4800
PDRPLAAGEV RIAVRAAGLN FRDVTVALGV VADDRPLGSE AAGVVLETGP
4810 4820 4830 4840 4850
GVHDLAPGDR VLGMLAGAFG PVAITDRRLL GRVPEGWTFP QAASVVTVFA
4860 4870 4880 4890 4900
TAWYGLVDLA ELRTGEKVLI HAAATGVGAA ALQIARHLGA DVYATASTPK
4910 4920 4930 4940 4950
QHLVDLAPTH IADSRSTAFA DTFPPADVVL NSLTGELLDA STALLTPGGR
4960 4970 4980 4990 5000
FIEMGKTDIR HHAQQPFDLM DAGPDRLQQI ITQLLDLFAN GTLHPLPVHA
5010 5020 5030 5040 5050
WDVRQAREAF GWMSSGRHTG KLVLTVPRPL DPEGAVIITG GSGTLAGILA
5060 5070 5080 5090 5100
RHLNHPHTYL LSRTPPPDTT PGTHLRCDVS DPTQLATALA QIPQPLTGIF
5110 5120 5130 5140 5150
HTAATLDDAL LDNLTPQRID TVLKPKADAA WHLHHQTRHT DLTAFVLYSA
5160 5170 5180 5190 5200
VAGVMGSPGQ GNYVAANAFL DALAEHRQAR GLPAQSLAWG MWADVSALTA
5210 5220 5230 5240 5250
KLTDADRERI RRSGFPPLSA ADGMRLFDSA ARTPEPVVVA TTVDVTRLDG
5260 5270 5280 5290 5300
PVAPLLRGLV AHRSGPVRAV ARNADDEPLA ARLAGHTAAE QRRVMQEVVL
5310 5320 5330 5340 5350
RQAAAVLAYG LGEQVAADRP FRDLGFDSLT AVDLRNRLAA ETGLRLPTTV
5360 5370 5380 5390 5400
VFSHPTAEAL ATHLLELLDA PAALTAGASL PAVTAAPGTA ARDQDEPIAI
5410 5420 5430 5440 5450
VAMACRLPGG VTSPEELWRL VESGTDAITM APGDRGWDLD ALYDPDPDAV
5460 5470 5480 5490 5500
GKAYNLRGGF LEGAAEFDAA FFDISPRESL GMDPQQRLLL ETAWEAIERG
5510 5520 5530 5540 5550
RINPASLHGR EIGVYVGAAA QGYGLGAEDT EGNAITGGST SLLSGRLAYV
5560 5570 5580 5590 5600
LGLEGPSVTV DTACSSSLVA LHLACQGLRL GECELALAGG VSVLSSPAAF
5610 5620 5630 5640 5650
VEFSRQRGLA ADGRCKSFGS GADGTTWAEG VGVLVLERLS DAERLGHTVL
5660 5670 5680 5690 5700
AVVRGSAVTS DGASNGLTAP NGLAQQRVIR KALAAAGLTA ADVDLVEGHG
5710 5720 5730 5740 5750
TGTRLGDPVE ADALLATYGQ NRQEPVWLGS LKSNIGHATA AAGVAGVIKT
5760 5770 5780 5790 5800
VQAIGAGTMP RTLHADEPSP AVDWTAGRVS LLTGNRPWPD DERARRAAVS
5810 5820 5830 5840 5850
AFGLSGTNAH VILEQHRPEP VAPRPPREEP RPLPWVLSAR TPAALRAQAA
5860 5870 5880 5890 5900
RLRDHLAAVP DADPLDIGYA LATSRARFTH RAAVVATSSD EFRAGLDSVA
5910 5920 5930 5940 5950
DGVEAPGVVG GTARERRVAF LFDGQGAQRV GMGRELHGRF PVFAAAWDEV
5960 5970 5980 5990 6000
SDAFGKHLEH SPTDVFHGEH GDLAHDTLYA QVGLFTLEVA LLRLLEHWGV
6010 6020 6030 6040 6050
RPDVLVGHSV GEVTAAYAAG VLTLADATAL IVARGRALRA LPPGAMTAVD
6060 6070 6080 6090 6100
GSPAEVGAFT GLDIAAVNGP SAVVLTGSPD DVTAFEREWA AAGRRAKRLD
6110 6120 6130 6140 6150
VGHAFHSRHV DGALDDFRTV LESLSFGAAR LPVVSTTTGR DAAGDLATPE
6160 6170 6180 6190 6200
HWLRHARRPV LFADAVRELA DLGVNMFVAV GPSGALASAA SENTGGSAGT
6210 6220 6230 6240 6250
YHAVLRARTG EENAALTAVA ELHAHGAPVD LAAVLAGGRP VDLPVYPFQH
6260 6270 6280 6290 6300
RSYWLAPAVG GGSPTAVPDT GRPAEPDPDD LTVAEIVRRR AAALLGIADP
6310 6320 6330 6340 6350
GDVDADTTFF ALGFDSLAVQ RLRNQLTAAT GLDLPTAVLF DHDTPSALTA
6360 6370 6380 6390 6400
YLEEQLGDGA DDDAPTVLAL LAEMESLDAA DIAATPAPER AAIADLLDKL

SRTWKDHR
Length:6,408
Mass (Da):670,966
Last modified:April 5, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB0A5892C1D391DF8
GO

Sequence databases

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EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
HM116536 Genomic DNA Translation: ADU56250.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HM116536 Genomic DNA Translation: ADU56250.1

3D structure databases

Database of comparative protein structure models

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ModBasei
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

Gene3Di1.10.1200.10, 4 hits
3.10.129.110, 3 hits
3.40.366.10, 4 hits
3.40.47.10, 4 hits
InterProiView protein in InterPro
IPR001227 Ac_transferase_dom_sf
IPR036736 ACP-like_sf
IPR014043 Acyl_transferase
IPR016035 Acyl_Trfase/lysoPLipase
IPR013154 ADH_N
IPR011032 GroES-like_sf
IPR032821 KAsynt_C_assoc
IPR018201 Ketoacyl_synth_AS
IPR014031 Ketoacyl_synth_C
IPR014030 Ketoacyl_synth_N
IPR016036 Malonyl_transacylase_ACP-bd
IPR036291 NAD(P)-bd_dom_sf
IPR020801 PKS_acyl_transferase
IPR020841 PKS_Beta-ketoAc_synthase_dom
IPR020807 PKS_dehydratase
IPR042104 PKS_dehydratase_sf
IPR020843 PKS_ER
IPR013968 PKS_KR
IPR020806 PKS_PP-bd
IPR015083 Polyketide_synth_docking
IPR009081 PP-bd_ACP
IPR006162 Ppantetheine_attach_site
IPR016039 Thiolase-like
PfamiView protein in Pfam
PF00698 Acyl_transf_1, 4 hits
PF08240 ADH_N, 2 hits
PF08990 Docking, 1 hit
PF16197 KAsynt_C_assoc, 4 hits
PF00109 ketoacyl-synt, 4 hits
PF02801 Ketoacyl-synt_C, 4 hits
PF08659 KR, 3 hits
PF00550 PP-binding, 4 hits
PF14765 PS-DH, 2 hits
SMARTiView protein in SMART
SM00827 PKS_AT, 4 hits
SM00826 PKS_DH, 3 hits
SM00829 PKS_ER, 2 hits
SM00825 PKS_KS, 4 hits
SM00823 PKS_PP, 4 hits
SUPFAMiSSF47336 SSF47336, 4 hits
SSF50129 SSF50129, 2 hits
SSF51735 SSF51735, 8 hits
SSF52151 SSF52151, 4 hits
SSF53901 SSF53901, 4 hits
SSF55048 SSF55048, 4 hits
PROSITEiView protein in PROSITE
PS00606 B_KETOACYL_SYNTHASE, 4 hits
PS50075 CARRIER, 4 hits
PS00012 PHOSPHOPANTETHEINE, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE9KTB8_STRKN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E9KTB8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: July 31, 2019
This is version 42 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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