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UniProtKB - F1NAB9 (F1NAB9_CHICK)

Entry version 59 (16 Oct 2019)
Sequence version 1 (03 May 2011)
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Protein
Submitted name:

Uncharacterized protein

Gene

COL20A1

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-GGA-1650814 Collagen biosynthesis and modifying enzymes
R-GGA-8948216 Collagen chain trimerization

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:COL20A1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiGallus gallus (Chicken)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9031 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archelosauria › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galloanserae › Galliformes › Phasianidae › Phasianinae › Gallus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000539 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 20Sequence analysisAdd BLAST20
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500326646521 – 1472Sequence analysisAdd BLAST1452

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		F1NAB9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSGALG00000005797 Expressed in 5 organ(s), highest expression level in heart

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		9031.ENSGALP00000009298

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini26 – 117Fibronectin type-IIIInterPro annotationAdd BLAST92
Domaini241 – 413VWFAInterPro annotationAdd BLAST173
Domaini446 – 535Fibronectin type-IIIInterPro annotationAdd BLAST90
Domaini536 – 627Fibronectin type-IIIInterPro annotationAdd BLAST92
Domaini628 – 715Fibronectin type-IIIInterPro annotationAdd BLAST88
Domaini716 – 807Fibronectin type-IIIInterPro annotationAdd BLAST92
Domaini808 – 897Fibronectin type-IIIInterPro annotationAdd BLAST90

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni118 – 232DisorderedSequence analysisAdd BLAST115
Regioni429 – 448DisorderedSequence analysisAdd BLAST20
Regioni1149 – 1307DisorderedSequence analysisAdd BLAST159
Regioni1348 – 1472DisorderedSequence analysisAdd BLAST125

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi118 – 152PolarSequence analysisAdd BLAST35
Compositional biasi163 – 179PolyampholyteSequence analysisAdd BLAST17
Compositional biasi180 – 211PolarSequence analysisAdd BLAST32
Compositional biasi212 – 226PolyampholyteSequence analysisAdd BLAST15

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG410IS5X Eukaryota
ENOG410YAN7 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00940000163709

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		F1NAB9

Identification of Orthologs from Complete Genome Data

More...OMAi		THVSKFD

Database of Orthologous Groups

More...OrthoDBi		67372at2759

TreeFam database of animal gene trees

More...TreeFami		TF329914

Family and domain databases

Conserved Domains Database

More...CDDi		cd00063 FN3, 6 hits

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.60.40.10, 6 hits
3.40.50.410, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR008160 Collagen
IPR013320 ConA-like_dom_sf
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR001791 Laminin_G
IPR002035 VWF_A
IPR036465 vWFA_dom_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01391 Collagen, 4 hits
PF00041 fn3, 6 hits
PF00092 VWA, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00060 FN3, 6 hits
SM00210 TSPN, 1 hit
SM00327 VWA, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF49265 SSF49265, 4 hits
SSF49899 SSF49899, 1 hit
SSF53300 SSF53300, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50853 FN3, 6 hits
PS50234 VWFA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

F1NAB9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLIRTCFFFA CLPVASHVWG RGGQGSSGRL KLTVLSEDRL QMKWKETEGS 
        60         70         80         90        100
INGYKVRVKP MAGDSEQEVM LKTKTPKATV GGLSPTKEYT LQVYVLNGSQ 
       110        120        130        140        150
EALFAKRKFV IEDLKNASQT RNNRRNSGAA PGKNLTSVGS STAEQSLGME 
       160        170        180        190        200
TAPPPLSTVL THPAKDRAEK KRHKGTQPKG SGETMRSQPS VGVTQTPPPT 
       210        220        230        240        250
TKSSQRATAN TEREPPGKEK PTRDSLRRGS QFQCDTSAMT DIVLLVDGSW 
       260        270        280        290        300
SIGRSNFKLI KEFLSALISP FNIAQDKIRV GLSQYSSDPR TEWDLSAYAT 
       310        320        330        340        350
RDQVLEAVRN LRYKGGNTFT GLALTHVLEQ NLKPDAGARL EAEKLVILLT 
       360        370        380        390        400
DGKSQDDANL AAQTLKNMGI EIFAIGVKNA DEAELKQVAS EPLELTVYNV 
       410        420        430        440        450
LDFPLLSSLV GRLTRVLCTR IKERSSKESA GRAVKDIPTN TGPELSPTDL 
       460        470        480        490        500
KISAVTSKSM HLAWSPPLSP PKKYRVVYYP SKGGTPKEVL LDGAISSLRL 
       510        520        530        540        550
SNLTSHTEYL VSVFPVYDTA VGDGLRGVTS TLPLSAPRSL RVSELSHNSI 
       560        570        580        590        600
RLSWKAAQGA AQYLVLCSAA PDGAEDYTTE IKVAEPEVLL DGLSPSTEYS 
       610        620        630        640        650
IAVYALYGED ASDPASIQET TLALSPPRYL SFSELSHSSV RVSWEPASPA 
       660        670        680        690        700
VKGHRVTYMS SRGSNTGEVE VPGTAMSTVL RPLSSLTQYF ISVRSMYDEG 
       710        720        730        740        750
DSFPITGNVT TLKVPPPRAL KVSELSENSL RLHWEAVAAS DVVVYQIKWS 
       760        770        780        790        800
TAGGEKPQEL SIAGNAATAV LPGLQKNTDY KISIWAYYKD GARSDTVSIQ 
       810        820        830        840        850
HRTTSRSPPT NLFIDSESPT SLQIHWKPPE GRIQHYRITY SPVSDPSTQQ 
       860        870        880        890        900
TIMASGKSSS VTLQPLLPDR AYKVTVSAVH YTGESESTTA TGRTAPVMSK 
       910        920        930        940        950
LPSIRGFVPS KTEACPPISS SAGSVRGFDM MEAFGLVEKE YASIKGVAME 
       960        970        980        990       1000
PFIFSGSRTF TLFRDIQLTL RTSDVHLFAI PPEHTISILL RLLPDTPKEP 
      1010       1020       1030       1040       1050
FAVWQITDED FQPLLGVNLD PSKKTLTYFN HDYKADLQEV SFDQQEVKKI 
      1060       1070       1080       1090       1100
FYGSFHKVHL AVSLFKIKLY LDCKKIAERP INTVGSISTA GFIMLGKVTR 
      1110       1120       1130       1140       1150
TRGPRSGSAS FQLQSLQVVC NSLGAEEDRC CDLPALRDEE SCPTIAPACS 
      1160       1170       1180       1190       1200
CTSGRPGLPG PPGPPGSPGR RGPQGEQGEP GPKGEPGPPG KVGPAGPSGQ 
      1210       1220       1230       1240       1250
QGSPGSQGIT IQGPVGPPGI KGEKGDTGSP GMQGIPGVQG APGRDGLQGA 
      1260       1270       1280       1290       1300
KGVRGLEGTA GPPGPPGPRG FQGVTGSRGS SGEKGPPGDV GPTGLPGPKG 
      1310       1320       1330       1340       1350
ERGEKGEPQS LATIYQLVSQ ACERMIQSHV LKFDSFIHEH ARKPVPVWEG 
      1360       1370       1380       1390       1400
RLKPGEPGSP GPPGPPGSNG EKGENGLPGQ TGKDGYPGER GAPGPKGEKG 
      1410       1420       1430       1440       1450
MAGANEEGIQ GPRGRTGPPG EVVLGNPGPK GYPGNTGPQG FPGVRGQPGQ 
      1460       1470 
PGYSGGCDVS GCYGPGRRDF IP
Length:1,472
Mass (Da):156,993
Last modified:May 3, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD99382B1F3EF4053
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AADN05000479 Genomic DNA No translation available.

NCBI Reference Sequences

More...RefSeqi		NP_001004392.2, NM_001004392.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSGALT00000009312; ENSGALP00000009298; ENSGALG00000005797

Database of genes from NCBI RefSeq genomes

More...GeneIDi		419243

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		gga:419243

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN05000479 Genomic DNA No translation available.
RefSeqiNP_001004392.2, NM_001004392.2

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000009298

Proteomic databases

PaxDbiF1NAB9

Genome annotation databases

EnsembliENSGALT00000009312; ENSGALP00000009298; ENSGALG00000005797
GeneIDi419243
KEGGigga:419243

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		57642

Phylogenomic databases

eggNOGiENOG410IS5X Eukaryota
ENOG410YAN7 LUCA
GeneTreeiENSGT00940000163709
InParanoidiF1NAB9
OMAiTHVSKFD
OrthoDBi67372at2759
TreeFamiTF329914

Enzyme and pathway databases

ReactomeiR-GGA-1650814 Collagen biosynthesis and modifying enzymes
R-GGA-8948216 Collagen chain trimerization

Gene expression databases

BgeeiENSGALG00000005797 Expressed in 5 organ(s), highest expression level in heart

Family and domain databases

CDDicd00063 FN3, 6 hits
Gene3Di2.60.40.10, 6 hits
3.40.50.410, 1 hit
InterProiView protein in InterPro
IPR008160 Collagen
IPR013320 ConA-like_dom_sf
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR001791 Laminin_G
IPR002035 VWF_A
IPR036465 vWFA_dom_sf
PfamiView protein in Pfam
PF01391 Collagen, 4 hits
PF00041 fn3, 6 hits
PF00092 VWA, 1 hit
SMARTiView protein in SMART
SM00060 FN3, 6 hits
SM00210 TSPN, 1 hit
SM00327 VWA, 1 hit
SUPFAMiSSF49265 SSF49265, 4 hits
SSF49899 SSF49899, 1 hit
SSF53300 SSF53300, 1 hit
PROSITEiView protein in PROSITE
PS50853 FN3, 6 hits
PS50234 VWFA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF1NAB9_CHICK
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F1NAB9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: October 16, 2019
This is version 59 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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