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Entry version 67 (08 May 2019)
Sequence version 1 (14 Dec 2011)
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Protein

Kinase suppressor of Ras A

Gene

ksr-1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Serine/threonine-protein kinase which positively regulates Ras-mediated signaling probably acting at the level of let-60/ras or/and lin-45/raf. Involved in sex myoblast migration (PubMed:8521513, PubMed:11882296). Plays a role in responses to M.nematophilum-mediated bacterial infection by promoting tail swelling and preventing constipation (PubMed:15268855). Functions redundantly with ksr-2 in the Ras-mediated regulation of larval survival, the development of excretory canal and in mpk-1 phosphorylation in somatic cells (PubMed:8521513, PubMed:11882296). In addition, involved in determining vulval precursor cell fate during vulval induction independently of its kinase activity (PubMed:8521514, PubMed:8521513, PubMed:10409742, PubMed:11882296). Plays a role in egg-laying (PubMed:23900546).6 Publications

Caution

The kinase may be catalytically inactive.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mg2+Curated

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei503ATPPROSITE-ProRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei600Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri215 – 269Phorbol-ester/DAG-typePROSITE-ProRule annotationAdd BLAST55
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi483 – 491ATPPROSITE-ProRule annotation9

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase
Biological processMeiosis
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CEL-5673000 RAF activation
R-CEL-5674135 MAP2K and MAPK activation
R-CEL-5675221 Negative regulation of MAPK pathway

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
G5EFD2

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Kinase suppressor of Ras ACurated (EC:2.7.11.1Curated)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ksr-1Imported
ORF Names:F13B9.5Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

WormBase

More...
WormBasei
F13B9.5 ; CE25854 ; WBGene00002239 ; ksr-1

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi277R → H in n2509; restores vulva development in a let-60 n1046gf mutant background. 1 Publication1
Mutagenesisi484G → E in ku113; restores vulva development in a let-60 n1046gf mutant background. 1 Publication1
Mutagenesisi494G → E in ku83; abnormal sex myoblast (SM) migration. Restores vulva development in a let-60 n1046gf mutant background. 1 Publication1
Mutagenesisi503K → M: Probable loss of kinase activity. Does not rescue vulva development in a let-60 n1046gf mutant background. 1 Publication1
Mutagenesisi531R → H in ku68; egg-laying defect in 14 percent of mutants. Arrest at the larval stage in 12 percent of mutants and abnormal sex myoblast (SM) migration. Restores vulva development in a let-60 n1046gf mutant background. 2 Publications1
Mutagenesisi549G → E in n1860; arrest at the larval stage in 12 percent of mutants. Restores vulva development in a let-60 n1046gf mutant background. 1 Publication1
Mutagenesisi618D → A: Probable loss of kinase activity. Does not rescue vulva development in a let-60 n1046gf mutant background. 1 Publication1
Mutagenesisi630P → L or S in ku146 and n2522; restores vulva development in a let-60 n1046gf mutant background. 2 Publications1
Mutagenesisi696P → L in n2519; restores vulva development in a let-60 n1046gf mutant background. 1 Publication1
Mutagenesisi727C → Y in ku148; restores vulva development in a let-60 n1046gf mutant background. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004345541 – 771Kinase suppressor of Ras ACuratedAdd BLAST771

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
G5EFD2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
G5EFD2

PeptideAtlas

More...
PeptideAtlasi
G5EFD2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00002239 Expressed in 5 organ(s), highest expression level in multi-cellular organism

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with mek-2.

1 Publication

GO - Molecular functioni

Protein-protein interaction databases

The Eukaryotic Linear Motif resource for Functional Sites in Proteins

More...
ELMi
G5EFD2

STRING: functional protein association networks

More...
STRINGi
6239.F13B9.5.2

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini477 – 748Protein kinasePROSITE-ProRule annotationAdd BLAST272

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi318 – 321Poly-SerSequence analysis4

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri215 – 269Phorbol-ester/DAG-typePROSITE-ProRule annotationAdd BLAST55

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0193 Eukaryota
ENOG410Y4UP LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000173084

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
G5EFD2

Identification of Orthologs from Complete Genome Data

More...
OMAi
EVSPMRF

Database of Orthologous Groups

More...
OrthoDBi
281487at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
G5EFD2

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00029 C1, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR002219 PE/DAG-bd
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR001245 Ser-Thr/Tyr_kinase_cat_dom
IPR008266 Tyr_kinase_AS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07714 Pkinase_Tyr, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00109 C1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56112 SSF56112, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00109 PROTEIN_KINASE_TYR, 1 hit
PS50081 ZF_DAG_PE_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G5EFD2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMQTQVASRA GYSNLPQFGA GIAQDIKTQA INNLKECLKL TTINRFLTSS
60 70 80 90 100
YEEDAKSVER KIFSAVYQMT KIGLIDREKR EINAIWFTFV GLSAQNIRHL
110 120 130 140 150
EICSITDFNA LFSITNQELR SLADRGRLDV ETKRKLLQST VILQNHWNAY
160 170 180 190 200
HSRTSSGSTD EPSGQSTPAI VTPSPKFNVP SLSVTSAKMI QSSSMGFATT
210 220 230 240 250
PKSPKTSSRL VHAIPHKWHR STKFRFSGDA VCHFCQRPLG FGFLNAWEKC
260 270 280 290 300
RSCKWKVHTQ CKGRVGDSCG LTPDHLRFLF DKLIQENNGG MWKDPQSVPG
310 320 330 340 350
SRSMNEPAFQ FPDTAIDSSS STNSSAPSTP ALPAGISGNV SSLTAPYRSE
360 370 380 390 400
RKFLFPDTEN YSVHNRLPIL VISEGDHPTT TEIQQETENH NKSAAASMSG
410 420 430 440 450
NIESEGTIVA NHEDSTGSQE VDSEAAPSQE AVDKFNKRAD GGFTWERHAW
460 470 480 490 500
NMSTIRGPNA QASWNEVTIQ FETIEFDKQA PIIGRGRFGK VLRGFHYGDV
510 520 530 540 550
AVKVYTMEHI SDASKKAEEF KLEVSAYKNT RHDNIALFLG YFMSDGQYGM
560 570 580 590 600
VMSLSKGSQS LYTLLHVVRE KLDLATTRKI AQQICQAVSY LHTKKILHKD
610 620 630 640 650
LRSKNILLES KNKVVITDFG ILSMKRLAHP KQKSGYLTSK FWTNYIAPEL
660 670 680 690 700
AMAMRTEYDE YECDDFPFSE NSDVYAFGCV WFEMLTGALP YAGELPHQIL
710 720 730 740 750
FAKTQGIRPV LPNVKCTQEL KELLVSCWNT APQDRPTLTD INLKLTALPK
760 770
KPRVNRSPSF PVMMKSYEST F
Length:771
Mass (Da):86,434
Last modified:December 14, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB9EB1A3EDA4ACE44
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U38820 mRNA Translation: AAA92436.1
S80647 mRNA Translation: AAB35769.1
BX284606 Genomic DNA Translation: CCD69410.1

NCBI Reference Sequences

More...
RefSeqi
NP_509396.1, NM_076995.6

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
F13B9.5.1; F13B9.5.1; WBGene00002239
F13B9.5.2; F13B9.5.2; WBGene00002239

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
181082

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_F13B9.5

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38820 mRNA Translation: AAA92436.1
S80647 mRNA Translation: AAB35769.1
BX284606 Genomic DNA Translation: CCD69410.1
RefSeqiNP_509396.1, NM_076995.6

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

ELMiG5EFD2
STRINGi6239.F13B9.5.2

Proteomic databases

EPDiG5EFD2
PaxDbiG5EFD2
PeptideAtlasiG5EFD2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF13B9.5.1; F13B9.5.1; WBGene00002239
F13B9.5.2; F13B9.5.2; WBGene00002239
GeneIDi181082
KEGGicel:CELE_F13B9.5

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
181082
WormBaseiF13B9.5 ; CE25854 ; WBGene00002239 ; ksr-1

Phylogenomic databases

eggNOGiKOG0193 Eukaryota
ENOG410Y4UP LUCA
GeneTreeiENSGT00940000173084
InParanoidiG5EFD2
OMAiEVSPMRF
OrthoDBi281487at2759
PhylomeDBiG5EFD2

Enzyme and pathway databases

ReactomeiR-CEL-5673000 RAF activation
R-CEL-5674135 MAP2K and MAPK activation
R-CEL-5675221 Negative regulation of MAPK pathway
SignaLinkiG5EFD2

Miscellaneous databases

Protein Ontology

More...
PROi
PR:G5EFD2

Gene expression databases

BgeeiWBGene00002239 Expressed in 5 organ(s), highest expression level in multi-cellular organism

Family and domain databases

CDDicd00029 C1, 1 hit
InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR002219 PE/DAG-bd
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR001245 Ser-Thr/Tyr_kinase_cat_dom
IPR008266 Tyr_kinase_AS
PfamiView protein in Pfam
PF07714 Pkinase_Tyr, 1 hit
SMARTiView protein in SMART
SM00109 C1, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00109 PROTEIN_KINASE_TYR, 1 hit
PS50081 ZF_DAG_PE_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKSRA_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G5EFD2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 14, 2015
Last sequence update: December 14, 2011
Last modified: May 8, 2019
This is version 67 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
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