Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 66 (16 Oct 2019)
Sequence version 1 (14 Dec 2011)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Slit homolog 1 protein

Gene

slt-1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Functions as a ligand for sax-3 receptor during larval development. Acts via the sax-3/Robo receptor to direct ventral axon guidance and guidance at the midline during embryonic development.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CEL-376176 Signaling by ROBO receptors
R-CEL-9010553 Regulation of expression of SLITs and ROBOs

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Slit homolog 1 protein
Short name:
Slt-1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:slt-1
ORF Names:F40E10.4
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

WormBase

More...
WormBasei
F40E10.4 ; CE32412 ; WBGene00004854 ; slt-1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 16Sequence analysisAdd BLAST16
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000042095817 – 1410Slit homolog 1 proteinAdd BLAST1394

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi873 ↔ 884By similarity
Disulfide bondi878 ↔ 894By similarity
Disulfide bondi896 ↔ 905By similarity
Disulfide bondi912 ↔ 923By similarity
Disulfide bondi917 ↔ 933By similarity
Disulfide bondi935 ↔ 944By similarity
Disulfide bondi951 ↔ 962By similarity
Disulfide bondi956 ↔ 971By similarity
Disulfide bondi973 ↔ 982By similarity
Disulfide bondi989 ↔ 1002By similarity
Disulfide bondi996 ↔ 1011By similarity
Disulfide bondi1013 ↔ 1022By similarity
Disulfide bondi1029 ↔ 1040By similarity
Disulfide bondi1034 ↔ 1049By similarity
Disulfide bondi1051 ↔ 1060By similarity
Disulfide bondi1076 ↔ 1086By similarity
Disulfide bondi1081 ↔ 1097By similarity
Disulfide bondi1099 ↔ 1108By similarity
Disulfide bondi1259 ↔ 1285By similarity
Disulfide bondi1292 ↔ 1302By similarity
Disulfide bondi1297 ↔ 1314By similarity
Disulfide bondi1316 ↔ 1325By similarity
Disulfide bondi1332 ↔ 1368By similarity
Disulfide bondi1346 ↔ 1382By similarity
Disulfide bondi1357 ↔ 1398By similarity
Disulfide bondi1361 ↔ 1400By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
G5EFX6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
G5EFX6

PRoteomics IDEntifications database

More...
PRIDEi
G5EFX6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00004854 Expressed in 4 organ(s), highest expression level in multi-cellular organism

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with eva-1.

1 Publication

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
46459, 3 interactors

STRING: functional protein association networks

More...
STRINGi
6239.F40E10.4

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini17 – 43LRRNT 1Add BLAST27
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati22 – 42LRR 1Add BLAST21
Repeati43 – 66LRR 2Add BLAST24
Repeati67 – 90LRR 3Add BLAST24
Repeati91 – 114LRR 4Add BLAST24
Repeati116 – 138LRR 5Add BLAST23
Repeati140 – 162LRR 6Add BLAST23
Repeati163 – 186LRR 7Add BLAST24
Domaini195 – 243LRRCT 1Add BLAST49
Repeati219 – 242LRR 8Add BLAST24
Domaini259 – 286LRRNT 2Add BLAST28
Repeati286 – 309LRR 9Add BLAST24
Repeati310 – 333LRR 10Add BLAST24
Repeati335 – 357LRR 11Add BLAST23
Repeati358 – 381LRR 12Add BLAST24
Repeati383 – 405LRR 13Add BLAST23
Repeati407 – 430LRR 14Add BLAST24
Domaini417 – 466LRRCT 2Add BLAST50
Repeati442 – 465LRR 15Add BLAST24
Domaini484 – 511LRRNT 3Add BLAST28
Repeati489 – 510LRR 16Add BLAST22
Repeati511 – 535LRR 17Add BLAST25
Repeati536 – 559LRR 18Add BLAST24
Repeati561 – 583LRR 19Add BLAST23
Repeati585 – 607LRR 20Add BLAST23
Domaini619 – 671LRRCT 3Add BLAST53
Domaini677 – 703LRRNT 4Add BLAST27
Repeati681 – 703LRR 21Add BLAST23
Repeati704 – 726LRR 22Add BLAST23
Repeati727 – 750LRR 23Add BLAST24
Repeati752 – 774LRR 24Add BLAST23
Repeati775 – 798LRR 25Add BLAST24
Repeati800 – 823LRR 26Add BLAST24
Domaini810 – 859LRRCT 4Add BLAST50
Domaini871 – 906EGF-like 1PROSITE-ProRule annotationAdd BLAST36
Domaini908 – 945EGF-like 2PROSITE-ProRule annotationAdd BLAST38
Domaini947 – 983EGF-like 1; calcium-bindingPROSITE-ProRule annotationAdd BLAST37
Domaini985 – 1023EGF-like 3PROSITE-ProRule annotationAdd BLAST39
Domaini1025 – 1061EGF-like 2; calcium-bindingPROSITE-ProRule annotationAdd BLAST37
Domaini1072 – 1109EGF-like 4PROSITE-ProRule annotationAdd BLAST38
Domaini1112 – 1285Laminin G-likePROSITE-ProRule annotationAdd BLAST174
Repeati1197 – 1221LRR 27Add BLAST25
Domaini1288 – 1326EGF-like 5PROSITE-ProRule annotationAdd BLAST39
Domaini1332 – 1406CTCKPROSITE-ProRule annotationAdd BLAST75

Keywords - Domaini

EGF-like domain, Leucine-rich repeat, Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4237 Eukaryota
COG4886 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000167217

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
G5EFX6

KEGG Orthology (KO)

More...
KOi
K06839

Identification of Orthologs from Complete Genome Data

More...
OMAi
QYAGRAC

Database of Orthologous Groups

More...
OrthoDBi
28488at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
G5EFX6

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.80.10.10, 5 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013320 ConA-like_dom_sf
IPR000483 Cys-rich_flank_reg_C
IPR006207 Cys_knot_C
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR018097 EGF_Ca-bd_CS
IPR001791 Laminin_G
IPR001611 Leu-rich_rpt
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf
IPR000372 LRRNT

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00008 EGF, 3 hits
PF12661 hEGF, 1 hit
PF00054 Laminin_G_1, 1 hit
PF13855 LRR_8, 5 hits
PF01462 LRRNT, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00041 CT, 1 hit
SM00181 EGF, 7 hits
SM00179 EGF_CA, 7 hits
SM00282 LamG, 1 hit
SM00369 LRR_TYP, 15 hits
SM00082 LRRCT, 4 hits
SM00013 LRRNT, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49899 SSF49899, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00010 ASX_HYDROXYL, 2 hits
PS01225 CTCK_2, 1 hit
PS00022 EGF_1, 7 hits
PS01186 EGF_2, 5 hits
PS50026 EGF_3, 7 hits
PS01187 EGF_CA, 2 hits
PS50025 LAM_G_DOMAIN, 1 hit
PS51450 LRR, 20 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

G5EFX6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLICFIFILL IPESATCPAE CVCVDRTVSC VGQQLTEVPQ NIPNDTIRLD
60 70 80 90 100
LQDNEITKIG PNDFSSLMNL KALQLMDNQI VTIHNQSFSS LVFLQKLRLS
110 120 130 140 150
RNRIRHLPDN VFQNNLKLTH LDLSENDITV VSDAQLQGPE FLEVLNLDKN
160 170 180 190 200
HIFCLENNVI SSWVSLEVLT LNGNRLTTFE EPSNARFRQL DLFNNPWNCD
210 220 230 240 250
CRLRWMRKWL EKAEGQNKTV CATPLNLQGS SIEILQDKFM TCSGNRKRRY
260 270 280 290 300
KKTCETAEIC PLPCTCTGTT VDCRDSGLTY VPTNLPPSTT EIRLEQNQIS
310 320 330 340 350
SIPSHSFKNL KNLTRLDLSK NIITEIQPKA FLGLHNLHTL VLYGNNITDL
360 370 380 390 400
KSDTFEGLGS LQLLLLNANQ LTCIRRGTFD HVPKLSMLSL YDNDIKSISE
410 420 430 440 450
VTFQNLTSLS TLHLAKNPLI CDCNLQWLAQ INLQKNIETS GARCEQPKRL
460 470 480 490 500
RKKKFATLPP NKFKCKGSES FVSMYADSCF IDSICPTQCD CYGTTVDCNK
510 520 530 540 550
RGLNTIPTSI PRFATQLLLS GNNISTVDLN SNIHVLENLE VLDLSNNHIT
560 570 580 590 600
FINDKSFEKL SKLRELRLND NKLHHFSSMV LDEQSNLEIL DLSGNNIQCF
610 620 630 640 650
SSIFFNKATR IREIKVIGND LLCDCRILPL MSWLRSNSSH SIDIPPCQQF
660 670 680 690 700
QYSDNESDKQ RCAAFPEETC SDDSNLCPPK CSCLDRVVRC SNKNLTSFPS
710 720 730 740 750
RIPFDTTELY LDANYINEIP AHDLNRLYSL TKLDLSHNRL ISLENNTFSN
760 770 780 790 800
LTRLSTLIIS YNKLRCLQPL AFNGLNALRI LSLHGNDISF LPQSAFSNLT
810 820 830 840 850
SITHIAVGSN SLYCDCNMAW FSKWIKSKFI EAGIARCEYP NTVSNQLLLT
860 870 880 890 900
AQPYQFTCDS KVPTKLATKC DLCLNSPCKN NAICETTSSR KYTCNCTPGF
910 920 930 940 950
YGVHCENQID ACYGSPCLNN ATCKVAQAGR FNCYCNKGFE GDYCEKNIDD
960 970 980 990 1000
CVNSKCENGG KCVDLINSYR CDCPMEYEGK HCEDKLEYCT KKLNPCENNG
1010 1020 1030 1040 1050
KCIPINGSYS CMCSPGFTGN NCETNIDDCK NVECQNGGSC VDGILSYDCL
1060 1070 1080 1090 1100
CRPGYAGQYC EIPPMMDMEY QKTDACQQSA CGQGECVASQ NSSDFTCKCH
1110 1120 1130 1140 1150
EGFSGPSCDR QMSVGFKNPG AYLALDPLAS DGTITMTLRT TSKIGILLYY
1160 1170 1180 1190 1200
GDDHFVSAEL YDGRVKLVYY IGNFPASHMY SSVKVNDGLP HRISIRTSER
1210 1220 1230 1240 1250
KCFLQIDKNP VQIVENSGKS DQLITKGKEM LYIGGLPIEK SQDAKRRFHV
1260 1270 1280 1290 1300
KNSESLKGCI SSITINEVPI NLQQALENVN TEQSCSATVN FCAGIDCGNG
1310 1320 1330 1340 1350
KCTNNALSPK GYMCQCDSHF SGEHCDEKRI KCDKQKFRRH HIENECRSVD
1360 1370 1380 1390 1400
RIKIAECNGY CGGEQNCCTA VKKKQRKVKM ICKNGTTKIS TVHIIRQCQC
1410
EPTKSVLSEK
Length:1,410
Mass (Da):158,223
Last modified:December 14, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD33716A9C98EBA9D
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Z69792, AL022270 Genomic DNA Translation: CAA93668.3

Protein sequence database of the Protein Information Resource

More...
PIRi
D89711
T22025

NCBI Reference Sequences

More...
RefSeqi
NP_510437.2, NM_078036.5

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
F40E10.4.1; F40E10.4.1; WBGene00004854

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
181562

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_F40E10.4

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z69792, AL022270 Genomic DNA Translation: CAA93668.3
PIRiD89711
T22025
RefSeqiNP_510437.2, NM_078036.5

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi46459, 3 interactors
STRINGi6239.F40E10.4

Proteomic databases

EPDiG5EFX6
PaxDbiG5EFX6
PRIDEiG5EFX6

Genome annotation databases

EnsemblMetazoaiF40E10.4.1; F40E10.4.1; WBGene00004854
GeneIDi181562
KEGGicel:CELE_F40E10.4

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
181562
WormBaseiF40E10.4 ; CE32412 ; WBGene00004854 ; slt-1

Phylogenomic databases

eggNOGiKOG4237 Eukaryota
COG4886 LUCA
GeneTreeiENSGT00940000167217
InParanoidiG5EFX6
KOiK06839
OMAiQYAGRAC
OrthoDBi28488at2759
PhylomeDBiG5EFX6

Enzyme and pathway databases

ReactomeiR-CEL-376176 Signaling by ROBO receptors
R-CEL-9010553 Regulation of expression of SLITs and ROBOs

Miscellaneous databases

Protein Ontology

More...
PROi
PR:G5EFX6

Gene expression databases

BgeeiWBGene00004854 Expressed in 4 organ(s), highest expression level in multi-cellular organism

Family and domain databases

Gene3Di3.80.10.10, 5 hits
InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR000483 Cys-rich_flank_reg_C
IPR006207 Cys_knot_C
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR018097 EGF_Ca-bd_CS
IPR001791 Laminin_G
IPR001611 Leu-rich_rpt
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf
IPR000372 LRRNT
PfamiView protein in Pfam
PF00008 EGF, 3 hits
PF12661 hEGF, 1 hit
PF00054 Laminin_G_1, 1 hit
PF13855 LRR_8, 5 hits
PF01462 LRRNT, 2 hits
SMARTiView protein in SMART
SM00041 CT, 1 hit
SM00181 EGF, 7 hits
SM00179 EGF_CA, 7 hits
SM00282 LamG, 1 hit
SM00369 LRR_TYP, 15 hits
SM00082 LRRCT, 4 hits
SM00013 LRRNT, 4 hits
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS00010 ASX_HYDROXYL, 2 hits
PS01225 CTCK_2, 1 hit
PS00022 EGF_1, 7 hits
PS01186 EGF_2, 5 hits
PS50026 EGF_3, 7 hits
PS01187 EGF_CA, 2 hits
PS50025 LAM_G_DOMAIN, 1 hit
PS51450 LRR, 20 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSLIT1_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G5EFX6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2013
Last sequence update: December 14, 2011
Last modified: October 16, 2019
This is version 66 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again