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Entry version 42 (11 Dec 2019)
Sequence version 1 (31 Oct 2012)
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Protein
Submitted name:

Spt16p

Gene

SU7_1068

Organism
Saccharomyces arboricola (strain H-6 / AS 2.3317 / CBS 10644) (Yeast)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Spt16pImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:SU7_1068Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces arboricola (strain H-6 / AS 2.3317 / CBS 10644) (Yeast)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1160507 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006968 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome VII

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini6 – 169FACT-Spt16_NlobInterPro annotationAdd BLAST164
Domaini554 – 708SPT16InterPro annotationAdd BLAST155
Domaini835 – 925Rtt106InterPro annotationAdd BLAST91

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni450 – 475DisorderedSequence analysisAdd BLAST26
Regioni769 – 798DisorderedSequence analysisAdd BLAST30
Regioni957 – 1036DisorderedSequence analysisAdd BLAST80

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili214 – 234Sequence analysisAdd BLAST21
Coiled coili492 – 512Sequence analysisAdd BLAST21
Coiled coili637 – 664Sequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi777 – 798PolyampholyteSequence analysisAdd BLAST22
Compositional biasi960 – 1018AcidicSequence analysisAdd BLAST59
Compositional biasi1019 – 1036PolyampholyteSequence analysisAdd BLAST18

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Conserved Domains Database

More...
CDDi
cd01091 CDC68-like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.29.30, 1 hit
3.40.350.10, 1 hit
3.90.230.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029149 Creatin/AminoP/Spt16_NTD
IPR036005 Creatinase/aminopeptidase-like
IPR013719 DUF1747
IPR029148 FACT-Spt16_Nlobe
IPR013953 FACT_Spt16
IPR000994 Pept_M24
IPR011993 PH-like_dom_sf
IPR040258 Spt16
IPR033825 Spt16_M24

The PANTHER Classification System

More...
PANTHERi
PTHR13980 PTHR13980, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14826 FACT-Spt16_Nlob, 1 hit
PF00557 Peptidase_M24, 1 hit
PF08512 Rtt106, 1 hit
PF08644 SPT16, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01285 FACT-Spt16_Nlob, 1 hit
SM01287 Rtt106, 1 hit
SM01286 SPT16, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF55920 SSF55920, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

J8LP01-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEELNINFGI FKKRIESLYS KYNEFEGSPN SLLFVLGSSN AENPYQKTTI
60 70 80 90 100
LHNWLLSYEF PATLIALVPG KIVIITSSAK AKHLQKAVDL FKDPQSEIAL
110 120 130 140 150
ELWQRNNKEP EHNKKLFDDV IALIKSAGKT VGTPEKDSYQ GKFMTEWNPV
160 170 180 190 200
WEAAVKENEL NVIDVSLGLS KVWEVKDVNE QAFLSVSSKG SDKFMDLLSN
210 220 230 240 250
EMVRAVDEEL KITNAKLSDK IENKIDDVKF LKQLSPDLSA LCPPNHKFNF
260 270 280 290 300
DLLDWTYSPI IQSGKKFDLR VSARSTNDQL HGNGCILASC GIRYNNYCSN
310 320 330 340 350
ITRTFLIDPS EEMVSNYDFL LTLQKEIETN ILKIGRTPKE TYESVIEYIE
360 370 380 390 400
KAKPELVSNF TKNIGSLVGL EFRDANFILN VKNDYRKIQP GDCFNISFGF
410 420 430 440 450
NNLKDSQSGN NYALQLADTV QIPLEETEPL RFLTNYTKAK SQISFYFNNE
460 470 480 490 500
EEDGNNKKKS SPTTKVPSKP DRNSKILRTK LRGEARGGAE DAQKEQIRKE
510 520 530 540 550
NQKKLHEKLE KNGLLRFSAA DANGPDSEPR QYFKKYESYV RDSQLPTNIR
560 570 580 590 600
DLRIHVDWKS QTIILPIYGR PVPFHINSYK NGSKNEEGEY TYLRLNFNSP
610 620 630 640 650
GSSGGISKKV EELPYEESAD NQFVRSITLR SKDGDRMSET FKQIADLKKE
660 670 680 690 700
ATKREQERKA LADVVQQDKL IENKTGRTKR LDQIFVRPNP DTKRVPSTVF
710 720 730 740 750
IHENGIRFQS PLRTDSRIDI LFSNIKNLIF QSCKGELIVV IHIHLKNPIL
760 770 780 790 800
MGKKKIQDVQ FYREASDMSV DETGGGRRGQ SRFRRYGDED ELEQEQEERR
810 820 830 840 850
KRAALDKEFK YFADAIAEAS NGLLTVENTF RDLGFQGVPN RSAVFCMPTT
860 870 880 890 900
DCLVQLIEPP FLVINLEEVE ICILERVQFG LKNFDMVFVY KDFNKPVTHI
910 920 930 940 950
NTVPIESLDF LKQWLTDMDI PYTVSTINLN WATIMKSLQD DPYQFFLDGG
960 970 980 990 1000
WNFLATGSDD EASDESEEEI SEYEASEDDI SDESAFSEEE EGSEVDDDIS
1010 1020 1030
GDESEDFTGD ESEEGEDWDE LEKKAARADR GANFRD
Length:1,036
Mass (Da):118,490
Last modified:October 31, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFFF98850ACDFFEB9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
ALIE01000077 Genomic DNA Translation: EJS43842.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
EJS43842; EJS43842; SU7_1068

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ALIE01000077 Genomic DNA Translation: EJS43842.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblFungiiEJS43842; EJS43842; SU7_1068

Family and domain databases

CDDicd01091 CDC68-like, 1 hit
Gene3Di2.30.29.30, 1 hit
3.40.350.10, 1 hit
3.90.230.10, 1 hit
InterProiView protein in InterPro
IPR029149 Creatin/AminoP/Spt16_NTD
IPR036005 Creatinase/aminopeptidase-like
IPR013719 DUF1747
IPR029148 FACT-Spt16_Nlobe
IPR013953 FACT_Spt16
IPR000994 Pept_M24
IPR011993 PH-like_dom_sf
IPR040258 Spt16
IPR033825 Spt16_M24
PANTHERiPTHR13980 PTHR13980, 1 hit
PfamiView protein in Pfam
PF14826 FACT-Spt16_Nlob, 1 hit
PF00557 Peptidase_M24, 1 hit
PF08512 Rtt106, 1 hit
PF08644 SPT16, 1 hit
SMARTiView protein in SMART
SM01285 FACT-Spt16_Nlob, 1 hit
SM01287 Rtt106, 1 hit
SM01286 SPT16, 1 hit
SUPFAMiSSF55920 SSF55920, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiJ8LP01_SACAR
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: J8LP01
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: October 31, 2012
Last modified: December 11, 2019
This is version 42 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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