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Entry version 47 (31 Jul 2019)
Sequence version 1 (06 Feb 2013)
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Protein
Submitted name:

Collagen type XI alpha 2 pseudogene 1

Gene

col11a2p1

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-XTR-1442490 Collagen degradation
R-XTR-1650814 Collagen biosynthesis and modifying enzymes
R-XTR-2022090 Assembly of collagen fibrils and other multimeric structures
R-XTR-3000171 Non-integrin membrane-ECM interactions
R-XTR-8874081 MET activates PTK2 signaling
R-XTR-8948216 Collagen chain trimerization

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Collagen type XI alpha 2 pseudogene 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:col11a2p1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri8364 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008143 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

Organism-specific databases

Xenopus laevis and tropicalis biology and genomics resource

More...
Xenbasei
XB-GENE-876669 col11a2p1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
K9J850

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSXETG00000012724 Expressed in 7 organ(s), highest expression level in embryo

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
8364.ENSXETP00000027837

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1756 – 1983Fibrillar collagen NC1InterPro annotationAdd BLAST228

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni283 – 302DisorderedSequence analysisAdd BLAST20
Regioni626 – 683DisorderedSequence analysisAdd BLAST58
Regioni718 – 1738DisorderedSequence analysisAdd BLAST1021

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi284 – 302PolarSequence analysisAdd BLAST19
Compositional biasi635 – 649Pro-richSequence analysisAdd BLAST15
Compositional biasi957 – 974PolyampholyteSequence analysisAdd BLAST18
Compositional biasi1116 – 1131Pro-richSequence analysisAdd BLAST16
Compositional biasi1314 – 1329PolyampholyteSequence analysisAdd BLAST16
Compositional biasi1405 – 1419Pro-richSequence analysisAdd BLAST15
Compositional biasi1708 – 1724Pro-richSequence analysisAdd BLAST17

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3544 Eukaryota
ENOG410XNMM LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159762

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
K9J850

Identification of Orthologs from Complete Genome Data

More...
OMAi
GPVCFQG

TreeFam database of animal gene trees

More...
TreeFami
TF323987

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008160 Collagen
IPR013320 ConA-like_dom_sf
IPR000885 Fib_collagen_C
IPR001791 Laminin_G

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01410 COLFI, 1 hit
PF01391 Collagen, 5 hits
PF02210 Laminin_G_2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00038 COLFI, 1 hit
SM00282 LamG, 1 hit
SM00210 TSPN, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49899 SSF49899, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51461 NC1_FIB, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

K9J850-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
DPIDVLKGLQ LHLQPEGVKK TTGLCPVRRS GTGADVAFRI SKQAQISAPT
60 70 80 90 100
RQLFPVGKFP EDFSIMALVR AKNGLQSFLL SIYSEQGTQQ IGVELGHSPV
110 120 130 140 150
FLFEDQNGKP APEDYPIFRG INLADGKWHR IALSVQKKSV TLILDCKKKI
160 170 180 190 200
TQQLPRGNKP IVDTKGITVF GTRILDEESF EGDIQQLLIA SNPQAAYDYC
210 220 230 240 250
EHYSPDCDSL PNAPQAQDPN PRVDYAEEEV EYYEYPYYYD NKEEGTPAPP
260 270 280 290 300
TVKALEEGVE EQVTSGCVIV SILGVMSHSI SFHPAPGSEK QSQKPQAANQ
310 320 330 340 350
AEAKGASSCQ ECQQGEKRSS GQGPCQTQHP NFLLYNTSCP IPKDPSLTPD
360 370 380 390 400
LIVTPEPTIS EKELDYTAPP LEEEEAYGVL EEKATQDVSP SPQDESYTVI
410 420 430 440 450
ITPPPVYTST FGVLLYFTLH PSPLHPSLFF PHLLPSWKAK EQEPSMAAKG
460 470 480 490 500
SDSFTEEYMT GEEDNPTGGL DYEYVYKDYT EGSETTHLGP VLSAETPESG
510 520 530 540 550
GVSSLVQSPC KLTKNKKLLY TTCTFPKLQQ SLLFSVFLCD AISFVTVSFP
560 570 580 590 600
VLLMPRSSMT ILRHKAADHK LLYQSENSEV NEYHSVFRQS TKAPLVLHAE
610 620 630 640 650
VNEAFSGPRG IKGDKGEPAV MEPGMLVEGP PGAEGPAGLP GPPGRHGHPG
660 670 680 690 700
PVGDPGERGP PGRAGLPGAN GLPGQPGSSV MLPFRLGNSA GAKGPIVAAQ
710 720 730 740 750
EAQAQAILQQ ARLALRGPSG PMGYTGRSGP LGPPGSPGLK GESGDVGPQG
760 770 780 790 800
QRGPQGLAGP PGKAGRRGRS GADGARGLPG EFGLKGDRGF DGLPGLPGEK
810 820 830 840 850
GNRGDSGVQG PLGGPGEDGE RGADGEVGAR GLPGEPGVRG LLGPKGPPGI
860 870 880 890 900
PGPPGVRGMD GHVGPKGNLG PQGEPGPPGQ QGTPGTQGLS GPQGPVGPPG
910 920 930 940 950
EKGPHGKPGL PGIPGSDGPP GHPGKEGPAG TKGNLGPTGP QGPIGYPGPR
960 970 980 990 1000
GGKGIDGIRG LKGHKGEKGE DGFPGFKGDV GIKGDKGEGG VPGSRGEDGP
1010 1020 1030 1040 1050
EGPKGRSGPN GDPGPIGVIG EKGKLGVPGL PGYPGRQGAK GSLGFPGFPG
1060 1070 1080 1090 1100
SNGEKGARGL SGKSGPRGER GPSGPRGQRG PRGATGKSGP KGTSGGDGPS
1110 1120 1130 1140 1150
GPLGERGLPG PQGSNGFPGP KGPPGPPGKD GIPGHPGQRG EVGFQGKMGT
1160 1170 1180 1190 1200
TGPPGVVGSQ GTQGESGPMG ERGHPGPPGP PGEQGLSGPS GKEGTKGDPG
1210 1220 1230 1240 1250
PTGVGGKDGP AGLRGFPGER GLPGTPGGPG LKGNEGPAGP PGPAGSPGER
1260 1270 1280 1290 1300
GGPGQGGPIG PPGRPGPQGP AGAAGEKGVP GEKGPIGPAG RDGVQGPVGL
1310 1320 1330 1340 1350
PGPAGPPGIS GEDGDKGEVG EHGQKGAKGN KGEHGPPGPS GPIGSVGQPG
1360 1370 1380 1390 1400
AAGADGEPGP RGQQGVFGAK GDEGTRGFPG APGPIGLQGL PGPYGEKGET
1410 1420 1430 1440 1450
GDGGPMGPPG PPGPRGPAGP SGADGPQGPP GGIGNLGPQG EKGEPGETGV
1460 1470 1480 1490 1500
PGIKGEFGPK GPRGDRGEKG ESGQPGDPGP QGVKGPPGDD GPKGNPGPVG
1510 1520 1530 1540 1550
FPGDPGPPGE MGPRGQDGAK GDRGEDGEQG EAGSPGPTGE NGPPGPVGKR
1560 1570 1580 1590 1600
GPAGPSGPEG RQGEKGSKGE PGALGPPGKT GAVGPQGTAG KQGPEGLRGL
1610 1620 1630 1640 1650
PGAVGEQGRP GATGQAGPPG PMGPSGLPGL KGDTGAKGEK GHPGLIGLIG
1660 1670 1680 1690 1700
PTGEQGEKGD RGLPGPHGIP GVTGPIGPGG PAGSPGPQGP KGAKGATGQA
1710 1720 1730 1740 1750
GPKGQKGVQG PPGPPGPPGE VIQPLPFQMP KKSKRSIDAS QIMADEPAAD
1760 1770 1780 1790 1800
YTDGMEEIYG SLNAIKKDIE LMRTPMGTKE HPARTCQDLK LCHPELPDGE
1810 1820 1830 1840 1850
YWIDPNQGCT RDSFKVFCNF TAGESCIFPS KDIEKVKMSS WSSEKRETWY
1860 1870 1880 1890 1900
SQYRSGRKLF YICLEGNAIG VVQLTFLRLL STYVHQNFTY HCHRSAAWHL
1910 1920 1930 1940 1950
TSSDSYQKAL HFRGSNEEDL SFHTTPYIKA LRDGCAMRKG TEKTVLEIYT
1960 1970 1980
PRVEQLPLTD AMFMDFGEPN QKFGFEVGPV CFLG
Length:1,984
Mass (Da):201,112
Last modified:February 6, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCD8A3E3D10B7ACFB
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAMC01083594 Genomic DNA No translation available.
AAMC01083595 Genomic DNA No translation available.
AAMC01083596 Genomic DNA No translation available.
AAMC01083597 Genomic DNA No translation available.
AAMC01083598 Genomic DNA No translation available.
AAMC01083599 Genomic DNA No translation available.
AAMC01083600 Genomic DNA No translation available.
AAMC01083601 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSXETT00000027837; ENSXETP00000027837; ENSXETG00000012724

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAMC01083594 Genomic DNA No translation available.
AAMC01083595 Genomic DNA No translation available.
AAMC01083596 Genomic DNA No translation available.
AAMC01083597 Genomic DNA No translation available.
AAMC01083598 Genomic DNA No translation available.
AAMC01083599 Genomic DNA No translation available.
AAMC01083600 Genomic DNA No translation available.
AAMC01083601 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi8364.ENSXETP00000027837

Proteomic databases

PaxDbiK9J850

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSXETT00000027837; ENSXETP00000027837; ENSXETG00000012724

Organism-specific databases

XenbaseiXB-GENE-876669 col11a2p1

Phylogenomic databases

eggNOGiKOG3544 Eukaryota
ENOG410XNMM LUCA
GeneTreeiENSGT00940000159762
InParanoidiK9J850
OMAiGPVCFQG
TreeFamiTF323987

Enzyme and pathway databases

ReactomeiR-XTR-1442490 Collagen degradation
R-XTR-1650814 Collagen biosynthesis and modifying enzymes
R-XTR-2022090 Assembly of collagen fibrils and other multimeric structures
R-XTR-3000171 Non-integrin membrane-ECM interactions
R-XTR-8874081 MET activates PTK2 signaling
R-XTR-8948216 Collagen chain trimerization

Gene expression databases

BgeeiENSXETG00000012724 Expressed in 7 organ(s), highest expression level in embryo

Family and domain databases

InterProiView protein in InterPro
IPR008160 Collagen
IPR013320 ConA-like_dom_sf
IPR000885 Fib_collagen_C
IPR001791 Laminin_G
PfamiView protein in Pfam
PF01410 COLFI, 1 hit
PF01391 Collagen, 5 hits
PF02210 Laminin_G_2, 1 hit
SMARTiView protein in SMART
SM00038 COLFI, 1 hit
SM00282 LamG, 1 hit
SM00210 TSPN, 1 hit
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS51461 NC1_FIB, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiK9J850_XENTR
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: K9J850
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2013
Last sequence update: February 6, 2013
Last modified: July 31, 2019
This is version 47 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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