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Entry version 153 (11 Dec 2019)
Sequence version 1 (01 Jan 1998)
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Protein
Submitted name:

LPS export ABC transporter ATP-binding protein

Gene

lptB

Organism
Vibrio cholerae
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi36 – 43ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandATP-bindingPROSITE-ProRule annotationImported, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
LPS export ABC transporter ATP-binding proteinImported
Submitted name:
Lipopolysaccharide ABC transporter ATP-binding proteinImported
Submitted name:
Lipopolysaccharide ABC transporter, ATP-binding protein LptBImported
Submitted name:
Putative ABC transporter ATP-binding proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:lptBImported
ORF Names:BC353_06960Imported, C9J66_07560Imported, FLM02_07035Imported, FXE88_03955Imported, FXF03_07065Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiVibrio choleraeImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri666 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000310727 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000266701 Componenti: Unassembled WGS sequence
  • UP000248087 Componenti: Unassembled WGS sequence
  • UP000319979 Componenti: Unassembled WGS sequence
  • UP000323819 Componenti: Unassembled WGS sequence
  • UP000322999 Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini4 – 237ABC transporterInterPro annotationAdd BLAST234

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4108IUZ Bacteria
COG1137 LUCA

KEGG Orthology (KO)

More...
KOi
K06861

Database of Orthologous Groups

More...
OrthoDBi
1220708at2

Family and domain databases

Conserved Domains Database

More...
CDDi
cd03218 ABC_YhbG, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593 AAA+_ATPase
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR032823 BCA_ABC_TP_C
IPR030921 LPS_export_LptB
IPR027417 P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00005 ABC_tran, 1 hit
PF12399 BCA_ABC_TP_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382 AAA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR04406 LPS_export_lptB, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O30650-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAILKAQHLA KSYKKRKVVS DVSLQVESGQ IVGLLGPNGA GKTTSFYMIV
60 70 80 90 100
GLVARDEGTI TIDDNDISIL PMHSRSRMGI GYLPQEASIF RKLSVEDNIM
110 120 130 140 150
AVLQTREELT HEERQDKLED LLEEFHIQHI RKSAGMALSG GERRRVEIAR
160 170 180 190 200
ALAANPQFIL LDEPFAGVDP ISVIDIKKII EHLRDRGLGV LITDHNVRET
210 220 230 240
LDVCEKAYIV SQGRLIAEGT PQDVLNNEQV KQVYLGEQFR L
Length:241
Mass (Da):26,950
Last modified:January 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i53DEAB53FE284944
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF013987 Genomic DNA Translation: AAC46369.1
CGII01000004 Genomic DNA Translation: CPR22661.1
PYRF01000005 Genomic DNA Translation: PYC83702.1
MCBA01000210 Genomic DNA Translation: RGP82276.1
VIOS01000019 Genomic DNA Translation: TQP15151.1
VSIJ01000023 Genomic DNA Translation: TXX66066.1
VSHU01000009 Genomic DNA Translation: TXY66938.1

Protein sequence database of the Protein Information Resource

More...
PIRi
E82065

NCBI Reference Sequences

More...
RefSeqi
WP_000996178.1, NZ_VSIT01000069.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AKO75988; AKO75988; EN12_12290
CSB04423; CSB04423; ERS013165_03177
CSB06334; CSB06334; ERS013166_03465
CSB13239; CSB13239; ERS013173_02621
CSB72923; CSB72923; ERS013262_00356
CSC13385; CSC13385; ERS013193_02291
CSC31613; CSC31613; ERS013198_02841
CSC47487; CSC47487; ERS013202_03082
CSC77887; CSC77887; ERS013201_03537
CSC81721; CSC81721; ERS013200_02346
CSD09795; CSD09795; ERS013140_02450
CSD11633; CSD11633; ERS013197_04789
KFD81655; KFD81655; DA89_1029
KFE27609; KFE27609; DN30_1649
OEC20228; OEC20228; BFX10_12430

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
vcq:EN18_15690
vcx:VAA049_366
vcz:VAB027_1338

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|666.1965.peg.835

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF013987 Genomic DNA Translation: AAC46369.1
CGII01000004 Genomic DNA Translation: CPR22661.1
PYRF01000005 Genomic DNA Translation: PYC83702.1
MCBA01000210 Genomic DNA Translation: RGP82276.1
VIOS01000019 Genomic DNA Translation: TQP15151.1
VSIJ01000023 Genomic DNA Translation: TXX66066.1
VSHU01000009 Genomic DNA Translation: TXY66938.1
PIRiE82065
RefSeqiWP_000996178.1, NZ_VSIT01000069.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6MJPX-ray2.85A/B1-241[»]
ModBaseiSearch...
SWISS-MODEL-WorkspaceiSubmit a new modelling project...
PDBe-KBiSearch...

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
2615191

Genome annotation databases

EnsemblBacteriaiAKO75988; AKO75988; EN12_12290
CSB04423; CSB04423; ERS013165_03177
CSB06334; CSB06334; ERS013166_03465
CSB13239; CSB13239; ERS013173_02621
CSB72923; CSB72923; ERS013262_00356
CSC13385; CSC13385; ERS013193_02291
CSC31613; CSC31613; ERS013198_02841
CSC47487; CSC47487; ERS013202_03082
CSC77887; CSC77887; ERS013201_03537
CSC81721; CSC81721; ERS013200_02346
CSD09795; CSD09795; ERS013140_02450
CSD11633; CSD11633; ERS013197_04789
KFD81655; KFD81655; DA89_1029
KFE27609; KFE27609; DN30_1649
OEC20228; OEC20228; BFX10_12430
KEGGivcq:EN18_15690
vcx:VAA049_366
vcz:VAB027_1338
PATRICifig|666.1965.peg.835

Phylogenomic databases

eggNOGiENOG4108IUZ Bacteria
COG1137 LUCA
KOiK06861
OrthoDBi1220708at2

Family and domain databases

CDDicd03218 ABC_YhbG, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR032823 BCA_ABC_TP_C
IPR030921 LPS_export_LptB
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00005 ABC_tran, 1 hit
PF12399 BCA_ABC_TP_C, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR04406 LPS_export_lptB, 1 hit
PROSITEiView protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiO30650_VIBCL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O30650
Secondary accession number(s): Q7DCT0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: December 11, 2019
This is version 153 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources
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