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1 to 25 of 647  Show
  1. 1
    "Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism."
    Kitada T., Asakawa S., Hattori N., Matsumine H., Yamamura Y., Minoshima S., Yokochi M., Mizuno Y., Shimizu N.
    Nature 392:605-608(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), INVOLVEMENT IN PARK2.
    Category: Pathology & Biotech, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 11 other entries.

  2. 2
    "Evidence for the presence of full-length PARK2 mRNA and Parkin protein in human blood."
    Kasap M., Akpinar G., Sazci A., Idrisoglu H.A., Vahaboglu H.
    Neurosci. Lett. 460:196-200(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, TISSUE SPECIFICITY, VARIANTS ARG-311 AND THR-371, IDENTIFICATION BY MASS SPECTROMETRY.
    Category: Subcellular Location, Expression, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  3. 3
    "Functional and molecular diversity of parkin."
    D'Agata V., Scapagnini G., Cavallaro S.
    Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 3 AND 4).
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  4. 4
    "Homo sapiens PARK2 transcript variants."
    Campello L., Esteve-Rudd J., Cuenca N., Martin-Nieto J.
    Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2; 7 AND 8).
    Category: Sequences.
    Tissue: Retina.
    Source: UniProtKB/Swiss-Prot (reviewed).
  5. 5
    "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Category: Sequences.
    Tissue: Testis.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 12927 other entries.

  6. 6
    "The DNA sequence and analysis of human chromosome 6."
    Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D.
    Beck S.
    Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 3761 other entries.

  7. 7
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  8. 8
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5).
    Category: Sequences.
    Tissue: Testis.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50448 other entries.

  9. 9
    Zou H.Q., Chan P.
    Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 312-361.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  10. 10
    "Immunohistochemical and subcellular localization of Parkin protein: absence of protein in autosomal recessive juvenile parkinsonism patients."
    Shimura H., Hattori N., Kubo S., Yoshikawa M., Kitada T., Matsumine H., Asakawa S., Minoshima S., Yamamura Y., Shimizu N., Mizuno Y.
    Ann. Neurol. 45:668-672(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION.
    Category: Subcellular Location.
    Source: UniProtKB/Swiss-Prot (reviewed).
  11. 11
    "Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity."
    Imai Y., Soda M., Takahashi R.
    J. Biol. Chem. 275:35661-35664(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION IN UBIQUITINATION.
    Category: Function, PTM / Processing.
    Source: UniProtKB/Swiss-Prot (reviewed).
  12. 12
    "Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase."
    Shimura H., Hattori N., Kubo S., Mizuno Y., Asakawa S., Minoshima S., Shimizu N., Iwai K., Chiba T., Tanaka K., Suzuki T.
    Nat. Genet. 25:302-305(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, CHARACTERIZATION OF VARIANTS PARK2 PRO-42 AND ARG-240.
    Category: Function, Pathology & Biotech, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 other entry.

  13. 13
    "Parkin functions as an E2-dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1."
    Zhang Y., Gao J., Chung K.K.K., Huang H., Dawson V.L., Dawson T.M.
    Proc. Natl. Acad. Sci. U.S.A. 97:13354-13359(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH UBE2L6 AND SEPTIN5, UBIQUITINATION OF SEPTIN5.
    Category: PTM / Processing, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 6 other entries.

  14. 14
    "An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin."
    Imai Y., Soda M., Inoue H., Hattori N., Mizuno Y., Takahashi R.
    Cell 105:891-902(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: UBIQUITINATION OF GPR37.
    Category: PTM / Processing.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 other entry.

  15. 15
    "Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease."
    Chung K.K.K., Zhang Y., Lim K.L., Tanaka Y., Huang H., Gao J., Ross C.A., Dawson V.L., Dawson T.M.
    Nat. Med. 7:1144-1150(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, CHARACTERIZATION OF VARIANTS PARK2 ARG-240; CYS-256; TRP-275 AND ASN-415, MUTAGENESIS OF CYS-337; CYS-421 AND CYS-431.
    Category: Function, Pathology & Biotech, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 3 other entries.

  16. 16
    "Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease."
    Shimura H., Schlossmacher M.G., Hattori N., Frosch M.P., Trockenbacher A., Schneider R., Mizuno Y., Kosik K.S., Selkoe D.J.
    Science 293:263-269(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION, CHARACTERIZATION OF VARIANTS PARK2 PRO-42 AND ARG-240.
    Category: Function, Subcellular Location, Pathology & Biotech, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  17. 17
    "Comparative genomics of the RBR family, including the Parkinson's disease-related gene parkin and the genes of the ariadne subfamily."
    Marin I., Ferrus A.
    Mol. Biol. Evol. 19:2039-2050(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: PRESENCE OF ATYPICAL RING FINGER DOMAINS.
    Category: Family & Domains.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 16 other entries.

  18. 18
    "CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity."
    Imai Y., Soda M., Hatakeyama S., Akagi T., Hashikawa T., Nakayama K., Takahashi R.
    Mol. Cell 10:55-67(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH STUB1 AND HSP70, UBIQUITINATION OF STUB1.
    Category: PTM / Processing, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 26 other entries.

  19. 19
    "The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI."
    Huynh D.P., Scoles D.R., Nguyen D., Pulst S.M.
    Hum. Mol. Genet. 12:2587-2597(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH SYT11, CHARACTERIZATION OF VARIANTS PARK2 GLY-289 AND ARG-418.
    Category: Pathology & Biotech, Interaction, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 and mapped to 24 other entries.

  20. 20
    "A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death."
    Imai Y., Soda M., Murakami T., Shoji M., Abe K., Takahashi R.
    J. Biol. Chem. 278:51901-51910(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH PACRG.
    Category: Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 12 and mapped to 16 other entries.

  21. 21
    "Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity."
    Staropoli J.F., McDermott C., Martinat C., Schulman B., Demireva E., Abeliovich A.
    Neuron 37:735-749(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH FBXW7 AND CUL1, UBIQUITINATION OF CYCLIN E.
    Category: Function, PTM / Processing, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 33 other entries.

  22. 22
    "Alterations in the common fragile site gene Parkin in ovarian and other cancers."
    Denison S.R., Wang F., Becker N.A., Schuele B., Kock N., Phillips L.A., Klein C., Smith D.I.
    Oncogene 22:8370-8378(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: INVOLVEMENT IN CANCER.
    Category: Pathology & Biotech.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 21 other entries.

  23. 23
    "Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27."
    Cesari R., Martin E.S., Calin G.A., Pentimalli F., Bichi R., McAdams H., Trapasso F., Drusco A., Shimizu M., Masciullo V., D'Andrilli G., Scambia G., Picchio M.C., Alder H., Godwin A.K., Croce C.M.
    Proc. Natl. Acad. Sci. U.S.A. 100:5956-5961(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INVOLVEMENT IN CANCER.
    Category: Function, Pathology & Biotech.
    Source: UniProtKB/Swiss-Prot (reviewed).
  24. 24
    "How does parkin ligate ubiquitin to Parkinson's disease?"
    Kahle P.J., Haass C.
    EMBO Rep. 5:681-685(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: REVIEW.
    Source: UniProtKB/Swiss-Prot (reviewed).
  25. 25
    "S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function."
    Chung K.K.K., Thomas B., Li X., Pletnikova O., Troncoso J.C., Marsh L., Dawson V.L., Dawson T.M.
    Science 304:1328-1331(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, UBIQUITINATION, S-NITROSYLATION.
    Category: Function, PTM / Processing.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 31 other entries.

1 to 25 of 647  Show
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