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UniProtKB - O95865 (DDAH2_HUMAN)

Entry version 165 (13 Nov 2019)
Sequence version 1 (01 May 1999)
Previous versions | rss
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Protein

N(G),N(G)-dimethylarginine dimethylaminohydrolase 2

Gene

DDAH2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei171Proton donorBy similarity1
Active sitei276NucleophileSequence analysis1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...BRENDAi		3.5.3.18 2681

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-203615 eNOS activation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 (EC:3.5.3.18)
Short name:
DDAH-2
Short name:
Dimethylarginine dimethylaminohydrolase 2
Alternative name(s):
DDAHII
Dimethylargininase-2
Protein G6a
S-phase protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DDAH2
Synonyms:DDAH, G6A, NG30
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:2716 DDAH2

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		604744 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_O95865

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		23564

Open Targets

More...OpenTargetsi		ENSG00000213722

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA27186

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		O95865

Chemistry databases

Drug and drug target database

More...DrugBanki		DB00155 L-Citrulline

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		DDAH2

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001711211 – 285N(G),N(G)-dimethylarginine dimethylaminohydrolase 2Add BLAST285

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		O95865

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		O95865

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		O95865

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		O95865

PeptideAtlas

More...PeptideAtlasi		O95865

PRoteomics IDEntifications database

More...PRIDEi		O95865

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		51100

2D gel databases

REPRODUCTION-2DPAGE

More...REPRODUCTION-2DPAGEi		IPI00000760
O95865

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		O95865

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		O95865

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas, and at very low levels in brain.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000213722 Expressed in 217 organ(s), highest expression level in endocervix

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		O95865 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		O95865 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA012509

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
Q156455EBI-749139,EBI-358993

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		117107, 37 interactors

Protein interaction database and analysis system

More...IntActi		O95865, 36 interactors

Molecular INTeraction database

More...MINTi		O95865

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000364945

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		O95865

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the DDAH family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG410ISNS Eukaryota
ENOG4111YMV LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00940000160769

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000161035

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		O95865

KEGG Orthology (KO)

More...KOi		K01482

Identification of Orthologs from Complete Genome Data

More...OMAi		MANMCPY

Database of Orthologous Groups

More...OrthoDBi		1469762at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		O95865

TreeFam database of animal gene trees

More...TreeFami		TF314737

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR033199 DDAH
IPR033202 DDAH2

The PANTHER Classification System

More...PANTHERi		PTHR12737 PTHR12737, 1 hit
PTHR12737:SF16 PTHR12737:SF16, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

O95865-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGTPGEGLGR CSHALIRGVP ESLASGEGAG AGLPALDLAK AQREHGVLGG 
        60         70         80         90        100
KLRQRLGLQL LELPPEESLP LGPLLGDTAV IQGDTALITR PWSPARRPEV 
       110        120        130        140        150
DGVRKALQDL GLRIVEIGDE NATLDGTDVL FTGREFFVGL SKWTNHRGAE 
       160        170        180        190        200
IVADTFRDFA VSTVPVSGPS HLRGLCGMGG PRTVVAGSSD AAQKAVRAMA 
       210        220        230        240        250
VLTDHPYASL TLPDDAAADC LFLRPGLPGV PPFLLHRGGG DLPNSQEALQ 
       260        270        280 
KLSDVTLVPV SCSELEKAGA GLSSLCLVLS TRPHS
Length:285
Mass (Da):29,644
Last modified:May 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB3D9B00F29492548
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5SSV3Q5SSV3_HUMAN
N(G),N(G)-dimethylarginine dimethyl...
DDAH2
226Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5SRR8Q5SRR8_HUMAN
N(G),N(G)-dimethylarginine dimethyl...
DDAH2
236Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y7N1H0Y7N1_HUMAN
N(G),N(G)-dimethylarginine dimethyl...
DDAH2
188Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A140T971A0A140T971_HUMAN
N(G),N(G)-dimethylarginine dimethyl...
DDAH2
225Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF070667 mRNA Translation: AAD20973.1
AJ012008 Genomic DNA Translation: CAB46079.1
AF087894 mRNA Translation: AAP97193.1
AF129756 Genomic DNA Translation: AAD18074.1
BA000025 Genomic DNA Translation: BAB63377.1
AL662899 Genomic DNA No translation available.
AL670886 Genomic DNA No translation available.
AL844216 Genomic DNA No translation available.
BX248244 Genomic DNA No translation available.
CR354443 Genomic DNA No translation available.
CR759787 Genomic DNA No translation available.
CR936239 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX03500.1
BC001435 mRNA Translation: AAH01435.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS4718.1

NCBI Reference Sequences

More...RefSeqi		NP_001289936.1, NM_001303007.1
NP_001289937.1, NM_001303008.1
NP_039268.1, NM_013974.2
XP_011512750.1, XM_011514448.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000375787; ENSP00000364943; ENSG00000213722
ENST00000375789; ENSP00000364945; ENSG00000213722
ENST00000375792; ENSP00000364949; ENSG00000213722
ENST00000383409; ENSP00000372901; ENSG00000206395
ENST00000400062; ENSP00000382935; ENSG00000206395
ENST00000400063; ENSP00000382936; ENSG00000206395
ENST00000411456; ENSP00000409396; ENSG00000226634
ENST00000413532; ENSP00000402594; ENSG00000226634
ENST00000413655; ENSP00000412800; ENSG00000233076
ENST00000414455; ENSP00000404342; ENSG00000225635
ENST00000424790; ENSP00000391632; ENSG00000233076
ENST00000426149; ENSP00000412327; ENSG00000228128
ENST00000427126; ENSP00000395372; ENSG00000228128
ENST00000430482; ENSP00000408148; ENSG00000227317
ENST00000434464; ENSP00000391833; ENSG00000228128
ENST00000437889; ENSP00000399023; ENSG00000227317
ENST00000443533; ENSP00000389552; ENSG00000226634
ENST00000444699; ENSP00000404851; ENSG00000225635
ENST00000447101; ENSP00000405515; ENSG00000233076
ENST00000451411; ENSP00000403154; ENSG00000227317
ENST00000454138; ENSP00000399357; ENSG00000225635

Database of genes from NCBI RefSeq genomes

More...GeneIDi		23564

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:23564

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF070667 mRNA Translation: AAD20973.1
AJ012008 Genomic DNA Translation: CAB46079.1
AF087894 mRNA Translation: AAP97193.1
AF129756 Genomic DNA Translation: AAD18074.1
BA000025 Genomic DNA Translation: BAB63377.1
AL662899 Genomic DNA No translation available.
AL670886 Genomic DNA No translation available.
AL844216 Genomic DNA No translation available.
BX248244 Genomic DNA No translation available.
CR354443 Genomic DNA No translation available.
CR759787 Genomic DNA No translation available.
CR936239 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX03500.1
BC001435 mRNA Translation: AAH01435.1
CCDSiCCDS4718.1
RefSeqiNP_001289936.1, NM_001303007.1
NP_001289937.1, NM_001303008.1
NP_039268.1, NM_013974.2
XP_011512750.1, XM_011514448.2

3D structure databases

SMRiO95865
ModBaseiSearch...

Protein-protein interaction databases

BioGridi117107, 37 interactors
IntActiO95865, 36 interactors
MINTiO95865
STRINGi9606.ENSP00000364945

Chemistry databases

DrugBankiDB00155 L-Citrulline

PTM databases

iPTMnetiO95865
PhosphoSitePlusiO95865

Polymorphism and mutation databases

BioMutaiDDAH2

2D gel databases

REPRODUCTION-2DPAGEiIPI00000760
O95865

Proteomic databases

EPDiO95865
jPOSTiO95865
MassIVEiO95865
PaxDbiO95865
PeptideAtlasiO95865
PRIDEiO95865
ProteomicsDBi51100

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		23564

Genome annotation databases

EnsembliENST00000375787; ENSP00000364943; ENSG00000213722
ENST00000375789; ENSP00000364945; ENSG00000213722
ENST00000375792; ENSP00000364949; ENSG00000213722
ENST00000383409; ENSP00000372901; ENSG00000206395
ENST00000400062; ENSP00000382935; ENSG00000206395
ENST00000400063; ENSP00000382936; ENSG00000206395
ENST00000411456; ENSP00000409396; ENSG00000226634
ENST00000413532; ENSP00000402594; ENSG00000226634
ENST00000413655; ENSP00000412800; ENSG00000233076
ENST00000414455; ENSP00000404342; ENSG00000225635
ENST00000424790; ENSP00000391632; ENSG00000233076
ENST00000426149; ENSP00000412327; ENSG00000228128
ENST00000427126; ENSP00000395372; ENSG00000228128
ENST00000430482; ENSP00000408148; ENSG00000227317
ENST00000434464; ENSP00000391833; ENSG00000228128
ENST00000437889; ENSP00000399023; ENSG00000227317
ENST00000443533; ENSP00000389552; ENSG00000226634
ENST00000444699; ENSP00000404851; ENSG00000225635
ENST00000447101; ENSP00000405515; ENSG00000233076
ENST00000451411; ENSP00000403154; ENSG00000227317
ENST00000454138; ENSP00000399357; ENSG00000225635
GeneIDi23564
KEGGihsa:23564

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		23564
DisGeNETi23564

GeneCards: human genes, protein and diseases

More...GeneCardsi		DDAH2
HGNCiHGNC:2716 DDAH2
HPAiHPA012509
MIMi604744 gene
neXtProtiNX_O95865
OpenTargetsiENSG00000213722
PharmGKBiPA27186

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG410ISNS Eukaryota
ENOG4111YMV LUCA
GeneTreeiENSGT00940000160769
HOGENOMiHOG000161035
InParanoidiO95865
KOiK01482
OMAiMANMCPY
OrthoDBi1469762at2759
PhylomeDBiO95865
TreeFamiTF314737

Enzyme and pathway databases

BRENDAi3.5.3.18 2681
ReactomeiR-HSA-203615 eNOS activation

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		DDAH2 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		23564
PharosiO95865

Protein Ontology

More...PROi		PR:O95865

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000213722 Expressed in 217 organ(s), highest expression level in endocervix
ExpressionAtlasiO95865 baseline and differential
GenevisibleiO95865 HS

Family and domain databases

InterProiView protein in InterPro
IPR033199 DDAH
IPR033202 DDAH2
PANTHERiPTHR12737 PTHR12737, 1 hit
PTHR12737:SF16 PTHR12737:SF16, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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MobiDB: a database of protein disorder and mobility annotations

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDDAH2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O95865
Secondary accession number(s): A2BEZ7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: November 13, 2019
This is version 165 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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