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1 to 25 of 34  Show
  1. 1
    "cDNA cloning of human N-Oct3, a nervous-system specific POU domain transcription factor binding to the octamer DNA motif."
    Schreiber E., Tobler A., Malipiero U., Schaffner W., Fontana A.
    Nucleic Acids Res. 21:253-258(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Category: Sequences.
    Tissue: Brain.
    Source: UniProtKB/Swiss-Prot (reviewed).
  2. 2
    "The brn-2 gene regulates the melanocytic phenotype and tumorigenic potential of human melanoma cells."
    Angus J., Thomson F., Murphy K., Baker E., Sutherland G.R., Parsons P.G., Sturm R.A.
    Oncogene 11:691-700(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Category: Sequences.
    Tissue: Liver.
    Source: UniProtKB/Swiss-Prot (reviewed).
  3. 3
    "The DNA sequence and analysis of human chromosome 6."
    Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D.
    Beck S.
    Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 3772 other entries.

  4. 4
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Category: Sequences.
    Tissue: Brain.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50454 other entries.

  5. 5
    "Expression of a large family of POU-domain regulatory genes in mammalian brain development."
    He X., Treacy M.N., Simmons D.M., Ingraham H.A., Swanson L.W., Rosenfeld M.G.
    Nature 340:35-42(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 280-404.
    Category: Sequences.
    Tissue: Brain.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 3 and mapped to 12 other entries.

  6. 6
    "PQBP-1, a novel polyglutamine tract binding protein, inhibits transcription activation by Brn-2 and affects cell survival."
    Waragai M., Lammers C.-H., Takeuchi S., Imafuku I., Udagawa Y., Kanazawa I., Kawabata M., Mouradian M.M., Okazawa H.
    Hum. Mol. Genet. 8:977-987(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH PQBP1.
    Category: Interaction.
    Tissue: Brain.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 5 other entries.

  7. 7
    "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 5395 and mapped to 17 other entries.

  8. 8
    "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-341, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Tissue: Leukemic T-cell.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 5604 other entries.

  9. 9
    "Toward a comprehensive characterization of a human cancer cell phosphoproteome."
    Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., Mohammed S.
    J. Proteome Res. 12:260-271(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: Sequences.
    Tissue: Erythroleukemia.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 13490 other entries.

  10. 10
    "Domains of Brn-2 that mediate homodimerization and interaction with general and melanocytic transcription factors."
    Smit D.J., Smith A.G., Parsons P.G., Muscat G.E., Sturm R.A.
    Eur. J. Biochem. 267:6413-6422(2000) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Source: IntAct:P20265.

    This publication is mapped to 5 other entries.

  11. 11
    "The Brn-2 transcription factor links activated BRAF to melanoma proliferation."
    Goodall J., Wellbrock C., Dexter T.J., Roberts K., Marais R., Goding C.R.
    Mol. Cell. Biol. 24:2923-2931(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: The results suggest that the high levels of Brn-2 expression observed in melanomas link BRAF signaling to increased proliferation.Imported.
    Source: GeneRIF:5454.

    This publication is mapped to 8 other entries.

  12. 12
    "Exclusion of mutations in the PRNP, JPH3, TBP, ATN1, CREBBP, POU3F2 and FTL genes as a cause of disease in Portuguese patients with a Huntington-like phenotype."
    Costa M.d.o. C., Teixeira-Castro A., Constante M., Magalhaes M., Magalhaes P., Cerqueira J., Vale J., Passao V., Barbosa C., Robalo C., Coutinho P., Barros J., Santos M.M., Sequeiros J., Maciel P.
    J. Hum. Genet. 51:645-651(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: Observational study of genotype prevalence. (HuGE Navigator)Imported.
    Source: GeneRIF:5454.

    This publication is mapped to 106 other entries.

  13. 13
    "Rb induces a proliferative arrest and curtails Brn-2 expression in retinoblastoma cells."
    Cobrinik D., Francis R.O., Abramson D.H., Lee T.C.
    Mol. Cancer 5:72-72(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Rb induces a proliferative arrest and regulates Brn-2 expression in retinoblastoma cellsImported.
    Source: GeneRIF:5454.

    This publication is mapped to 39 other entries.

  14. 14
    "Differential effects of phosphorylation on DNA binding properties of N Oct-3 are dictated by protein/DNA complex structures."
    Nieto L., Joseph G., Stella A., Henri P., Burlet-Schiltz O., Monsarrat B., Clottes E., Erard M.
    J. Mol. Biol. 370:687-700(2007) [PubMed] [Europe PMC] [Abstract]
    Category: PTM / Processing.
    Source: PhosphoSitePlus:P20265.
  15. 15
    "Brn-2 represses microphthalmia-associated transcription factor expression and marks a distinct subpopulation of microphthalmia-associated transcription factor-negative melanoma cells."
    Goodall J., Carreira S., Denat L., Kobi D., Davidson I., Nuciforo P., Sturm R.A., Larue L., Goding C.R.
    Cancer Res. 68:7788-7794(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Brn-2 regulates invasiveness and directly represses Mitf expression.Imported.
    Source: GeneRIF:5454.

    This publication is mapped to 10 other entries.

  16. 16
    "SOX9 and SOX10 but not BRN2 are required for nestin expression in human melanoma cells."
    Flammiger A., Besch R., Cook A.L., Maier T., Sturm R.A., Berking C.
    J. Invest. Dermatol. 129:945-953(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: SOX9 and SOX10 but not BRN2 seem to be required for nestin expression in human melanoma.Imported.
    Source: GeneRIF:5454.

    This publication is mapped to 22 other entries.

  17. 17
    Category: Interaction.
    Source: IntAct:P20265.

    This publication is mapped to 270 other entries.

  18. 18
    "Expression and purification of human full-length N Oct-3, a transcription factor involved in melanoma growth."
    Cabos-Siguier B., Steunou A.L., Joseph G., Alazard R., Ducoux-Petit M., Nieto L., Monsarrat B., Erard M., Clottes E.
    Protein Expr. Purif. 64:39-46(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Expression and purification of full-length BRN2 a transcription factor involved in melanoma growth are reported.Imported.
    Source: GeneRIF:5454.

    This publication is mapped to 1 other entry.

  19. 19
    "A genome-wide association study of schizophrenia using brain activation as a quantitative phenotype."
    Potkin S.G., Turner J.A., Guffanti G., Lakatos A., Fallon J.H., Nguyen D.D., Mathalon D., Ford J., Lauriello J., Macciardi F.
    Schizophr Bull 35:96-108(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: Associated with PSYCH: Brain imaging in schizophrenia (interaction).Imported, Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)Imported.
    Source: GAD:599351, GeneRIF:5454.

    This publication is mapped to 30 other entries.

  20. 20
    "Genome-wide analysis of POU3F2/BRN2 promoter occupancy in human melanoma cells reveals Kitl as a novel regulated target gene."
    Kobi D., Steunou A.L., Dembele D., Legras S., Larue L., Nieto L., Davidson I.
    Pigment Cell Melanoma Res 23:404-418(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: POU3F2 may regulate the properties of melanoma cells via autocrine KIT ligand signalling.Imported.
    Source: GeneRIF:5454.

    This publication is mapped to 7 other entries.

  21. 21
    "Inverse expression states of the BRN2 and MITF transcription factors in melanoma spheres and tumour xenografts regulate the NOTCH pathway."
    Thurber A.E., Douglas G., Sturm E.C., Zabierowski S.E., Smit D.J., Ramakrishnan S.N., Hacker E., Leonard J.H., Herlyn M., Sturm R.A.
    Oncogene 30:3036-3048(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: links BRN2 as an activator and MITF as a repressor of the NOTCH pathway in melanoma cells. Loss of the BRN2-MITF axis in antisense-ablated cell lines decreased the melanoma sphere-forming capability and cell adhesionImported.
    Source: GeneRIF:5454.

    This publication is mapped to 10 other entries.

  22. 22
    "Melanoma cell invasiveness is regulated by miR-211 suppression of the BRN2 transcription factor."
    Boyle G.M., Woods S.L., Bonazzi V.F., Stark M.S., Hacker E., Aoude L.G., Dutton-Regester K., Cook A.L., Sturm R.A., Hayward N.K.
    Pigment Cell Melanoma Res 24:525-537(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: a model for the apparent non-overlapping expression levels of BRN2 and MITF in melanoma mediated by miR-211 expression.Imported.
    Source: GeneRIF:5454.

    This publication is mapped to 1 other entry.

  23. 23
    "A phosphatidylinositol 3-kinase-Pax3 axis regulates Brn-2 expression in melanoma."
    Bonvin E., Falletta P., Shaw H., Delmas V., Goding C.R.
    Mol. Cell. Biol. 32:4674-4683(2012) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: PI3K has a crucial role in regulating Brn-2 and Pax3 expression and neoplasm invasiveness and it is a key determinant of melanoma subpopulation diversity.Imported.
    Source: GeneRIF:5454.

    This publication is mapped to 19 other entries.

  24. 24
    "BRN2 is a transcriptional repressor of CDH13 (T-cadherin) in melanoma cells."
    Ellmann L., Joshi M.B., Resink T.J., Bosserhoff A.K., Kuphal S.
    Lab. Invest. 92:1788-1800(2012) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: The present study investigated transcriptional regulation of CDH13 in melanoma. Found an inverse correlation between BRN2 and T-cadherin protein and transcript expression in melanoma.Imported.
    Source: GeneRIF:5454.

    This publication is mapped to 8 other entries.

  25. 25
    "Neural lineage-specific homeoprotein BRN2 is directly involved in TTF1 expression in small-cell lung cancer."
    Sakaeda M., Sato H., Ishii J., Miyata C., Kamma H., Shishido-Hara Y., Shimoyamada H., Fujiwara M., Endo T., Tanaka R., Kondo H., Goya T., Aoki I., Yazawa T.
    Lab. Invest. 93:408-421(2013) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: TTF1 expression in small-cell lung cancer is a cell lineage-specific phenomenon that involves the developing neural cell-specific homeoprotein BRN2.Imported.
    Source: GeneRIF:5454.

    This publication is mapped to 4 other entries.

1 to 25 of 34  Show
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