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1 to 25 of 159  Show
  1. 1
    "Identification of a novel gene expressed in activated natural killer cells and T cells."
    Dahl C.A., Schall R.P., He H., Cairns J.S.
    J. Immunol. 148:597-603(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), INDUCTION, VARIANT ASN-152.
    Category: Expression, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  2. 2
    "Interleukin-32: a cytokine and inducer of TNFalpha."
    Kim S.-H., Han S.-Y., Azam T., Yoon D.-Y., Dinarello C.A.
    Immunity 22:131-142(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS 2; 3 AND 4), ALTERNATIVE SPLICING, FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
    Category: Function, Subcellular Location, Expression, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 other entries.

  3. 3
    "A new variant of interleukin 32."
    Mao W., Han W., Salama A., Moldenhauer A.
    Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 7).
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  4. 4
    "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5).
    Category: Sequences.
    Tissue: Thalamus.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 12927 other entries.

  5. 5
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 6).
    Category: Sequences.
    Tissue: Stomach.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 5 other entries.

  6. 6
    "The sequence and analysis of duplication-rich human chromosome 16."
    Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J.
    Pennacchio L.A.
    Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 3627 other entries.

  7. 7
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  8. 8
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
    Category: Sequences.
    Tissue: Eye and Pancreas.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50448 other entries.

  9. 9
    "Mast cell and neutrophil peptidases attack an inactivation segment in hepatocyte growth factor to generate NK4-like antagonists."
    Raymond W.W., Cruz A.C., Caughey G.H.
    J. Biol. Chem. 281:1489-1494(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: A potential physiological pathway for inactivation of HGF and generation of NK4-like antagonists.
    Source: GeneRIF:9235.

    This publication is mapped to 8 other entries.

  10. 10
    "Involvement of IL-32 in activation-induced cell death in T cells."
    Goda C., Kanaji T., Kanaji S., Tanaka G., Arima K., Ohno S., Izuhara K.
    Int. Immunol. 18:233-240(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: results strongly indicate that IL-32 is involved in activation-induced cell death in T cells probably via its intracellular actions.
    Source: GeneRIF:9235.

    This publication is mapped to 3 other entries.

  11. 11
    Category: Function, PTM / Processing, Interaction.
    Annotation: Pathway. [Reactome:R-HSA-448634]. Proteinase 3 is a specific IL-32alpha binding protein independent of its enzymatic activity. [GeneRIF:9235].
    Source: Reactome:R-HSA-448634, GeneRIF:9235.

    This publication is mapped to 4 other entries.

  12. 12
    Category: Expression.
    Annotation: IL-32 strongly associated with TNFalpha IL-1beta and IL-18 appears to play a role in human rheumatoid arthritis and may be a novel target in autoimmune diseases.
    Source: GeneRIF:9235.

    This publication is mapped to 3 other entries.

  13. 13
    "Mycobacterium tuberculosis induces interleukin-32 production through a caspase- 1/IL-18/interferon-gamma-dependent mechanism."
    Netea M.G., Azam T., Lewis E.C., Joosten L.A., Wang M., Langenberg D., Meng X., Chan E.D., Yoon D.Y., Ottenhoff T., Kim S.H., Dinarello C.A.
    PLoS Med. 3:e277-e277(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: IL-32 is a cell-associated proinflammatory cytokine which is specifically stimulated by mycobacteria through a caspase-1- and IL-18-dependent production of interferon gamma.
    Source: GeneRIF:9235.

    This publication is mapped to 28 other entries.

  14. 14
    Category: Expression.
    Annotation: review of important role of IL32 in the pathogenesis of rheumatoid arthritis.
    Source: GeneRIF:9235.

    This publication is mapped to 3 other entries.

  15. 15
    "Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function."
    Marcondes A.M., Mhyre A.J., Stirewalt D.L., Kim S.H., Dinarello C.A., Deeg H.J.
    Proc. Natl. Acad. Sci. U.S.A. 105:2865-2870(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function.
    Source: GeneRIF:9235.

    This publication is mapped to 3 other entries.

  16. 16
    "Unique expression of a small IL-32 protein in the Jurkat leukemic T cell line."
    Ko N.Y., Chang S.H., Lee J.H., Kim N.W., Kim Y.M., Choi W.S., Choi J.D., Bae S.Y., Hong J.W., Jaekal J., Azam T., Her E., Kim S.H.
    Cytokine 42:121-127(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Data suggest that the constitutive expression of IL-32 mRNA as well as the predominant production of a smaller sized IL-32 isoform in Jurkat cells may implicate a role for IL-32 in human T cell leukemia.
    Source: GeneRIF:9235.

    This publication is mapped to 3 other entries.

  17. 17
    "Interleukin-32 induces the differentiation of monocytes into macrophage-like cells."
    Netea M.G., Lewis E.C., Azam T., Joosten L.A., Jaekal J., Bae S.Y., Dinarello C.A., Kim S.H.
    Proc. Natl. Acad. Sci. U.S.A. 105:3515-3520(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: induction of TNF IL-1beta and IL-6 by IL-32 is mediated by p38-MAPK; IL-32-induced monocyte-to-macrophage differentiation is mediated through nonapoptotic caspase-3-dependent mechanisms.
    Source: GeneRIF:9235.

    This publication is mapped to 11 other entries.

  18. 18
    "Activation of interleukin-32 pro-inflammatory pathway in response to influenza A virus infection."
    Li W., Liu Y., Mukhtar M.M., Gong R., Pan Y., Rasool S.T., Gao Y., Kang L., Hao Q., Peng G., Chen Y., Chen X., Wu J., Zhu Y.
    PLoS ONE 3:e1985-e1985(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: the interleukin-32 pro-inflammatory pathway is activated in response to influenza A virus infectio.
    Source: GeneRIF:9235.

    This publication is mapped to 3 other entries.

  19. 19
    "A human dendritic cell subset receptive to the Venezuelan equine encephalitis virus-derived replicon particle constitutively expresses IL-32."
    Nishimoto K.P., Laust A.K., Nelson E.L.
    J. Immunol. 181:4010-4018(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: Constitutive expression of IL-32 in an immature monocyte-derived dendritic cell subset may be related to the potency of expressed Venezuelan equine encephalitis (VEE) particle vector system as well as potentially to the pathogenesis of VEE.
    Source: GeneRIF:9235.

    This publication is mapped to 3 other entries.

  20. 20
    "Proteinase 3-processed form of the recombinant IL-32 separate domain."
    Kim S., Lee S., Her E., Bae S., Choi J., Hong J., Jaekal J., Yoon D., Azam T., Dinarello C.A., Kim S.
    BMB Rep 41:814-819(2008) [PubMed] [Europe PMC] [Abstract]
    Category: PTM / Processing.
    Annotation: The N-terminal IL-32 isoform gamma separate domain evidenced the highest levels of biological activity among the IL-32 separate domains.
    Source: GeneRIF:9235.

    This publication is mapped to 3 other entries.

  21. 21
    Category: Function.
    Annotation: This study introduces IL-32 as a critical regulator of endothelial function expanding the properties of this cytokine relevant to coagulation endothelial inflammation and atherosclerosis.
    Source: GeneRIF:9235.

    This publication is mapped to 6 other entries.

  22. 22
    "Tumor necrosis factor alpha-induced interleukin-32 is positively regulated via the Syk/protein kinase Cdelta/JNK pathway in rheumatoid synovial fibroblasts."
    Mun S.H., Kim J.W., Nah S.S., Ko N.Y., Lee J.H., Kim J.D., Kim D.K., Kim H.S., Choi J.D., Kim S.H., Lee C.K., Park S.H., Kim B.K., Kim H.S., Kim Y.M., Choi W.S.
    Arthritis Rheum. 60:678-685(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: IL-32 may be a newly identified prognostic biomarker in rheumatoid arthritis. Production of IL-32 in rheumatoid synovial fibroblasts is regulated by Syk/PKCdelta/JNK-mediated signaling events.
    Source: GeneRIF:9235.

    This publication is mapped to 14 other entries.

  23. 23
    "Negative feedback regulation of IL-32 production by iNOS activation in response to dsRNA or influenza virus infection."
    Li W., Yang F., Liu Y., Gong R., Liu L., Feng Y., Hu P., Sun W., Hao Q., Kang L., Wu J., Zhu Y.
    Eur. J. Immunol. 39:1019-1024(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Influenza A virus infection activates IL-32 and iNOS expression by a heretofore unrecognized complex mechanism in which the two pro-inflammatory factors regulate each other involving positive and negative feedback regulatory loops.
    Source: GeneRIF:9235.

    This publication is mapped to 3 other entries.

  24. 24
    "Molecular characterization of IL-32 in human endothelial cells."
    Kobayashi H., Lin P.C.
    Cytokine 46:351-358(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Data show that the IL-32 gene is expressed in human endothelial cells and Akt strongly induces its expression.
    Source: GeneRIF:9235.

    This publication is mapped to 3 other entries.

  25. 25
    Category: Expression.
    Annotation: High IL-32 is associated with Pancreatic Cancer.
    Source: GeneRIF:9235.

    This publication is mapped to 3 other entries.

1 to 25 of 159  Show
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