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Entry version 178 (18 Sep 2019)
Sequence version 2 (23 Jan 2007)
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Protein

60S ribosomal protein L27a

Gene

RPL27A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
60S ribosomal protein L27a
Alternative name(s):
Large ribosomal subunit protein uL151 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RPL27A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:10329 RPL27A

Online Mendelian Inheritance in Man (OMIM)

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MIMi
603637 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P46776

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
6157

Open Targets

More...
OpenTargetsi
ENSG00000166441

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA34708

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RPL27A

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001048791 – 14860S ribosomal protein L27aAdd BLAST148

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei39(3S)-3-hydroxyhistidine1 Publication1
Modified residuei47N6-acetyllysineCombined sources1
Modified residuei55N6-acetyllysineCombined sources1
Modified residuei68PhosphoserineCombined sources1
Modified residuei110N6-acetyllysineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Hydroxylated on His-39 by MINA.1 Publication

Keywords - PTMi

Acetylation, Hydroxylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P46776

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
P46776

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
P46776

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P46776

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P46776

PeptideAtlas

More...
PeptideAtlasi
P46776

PRoteomics IDEntifications database

More...
PRIDEi
P46776

ProteomicsDB human proteome resource

More...
ProteomicsDBi
55758

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
P46776

2D gel databases

Two-dimensional polyacrylamide gel electrophoresis database from the Geneva University Hospital

More...
SWISS-2DPAGEi
P46776

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P46776

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P46776

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P46776

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000166441 Expressed in 131 organ(s), highest expression level in ectocervix

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P46776 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P46776 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA060776
HPA063379

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
GTF2F2P139842EBI-350581,EBI-1030560

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
112076, 176 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
P46776

Database of interacting proteins

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DIPi
DIP-33121N

Protein interaction database and analysis system

More...
IntActi
P46776, 46 interactors

Molecular INTeraction database

More...
MINTi
P46776

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000346015

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P46776

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1742 Eukaryota
COG0200 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000005534

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231263

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P46776

KEGG Orthology (KO)

More...
KOi
K02900

Identification of Orthologs from Complete Genome Data

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OMAi
WGRVGQH

Database of Orthologous Groups

More...
OrthoDBi
1445443at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P46776

TreeFam database of animal gene trees

More...
TreeFami
TF313742

Family and domain databases

HAMAP database of protein families

More...
HAMAPi
MF_01341 Ribosomal_L15, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036227 L18e/L15P_sf
IPR030878 Ribosomal_L15
IPR001196 Ribosomal_L15_CS
IPR021131 Ribosomal_L18e/L15P

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00828 Ribosomal_L27A, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52080 SSF52080, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00475 RIBOSOMAL_L15, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

P46776-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPSRLRKTRK LRGHVSHGHG RIGKHRKHPG GRGNAGGLHH HRINFDKYHP
60 70 80 90 100
GYFGKVGMKH YHLKRNQSFC PTVNLDKLWT LVSEQTRVNA AKNKTGAAPI
110 120 130 140
IDVVRSGYYK VLGKGKLPKQ PVIVKAKFFS RRAEEKIKSV GGACVLVA
Length:148
Mass (Da):16,561
Last modified:January 23, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCB5E09C91507798F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PLX7E9PLX7_HUMAN
60S ribosomal protein L27a
RPL27A
113Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PLL6E9PLL6_HUMAN
60S ribosomal protein L27a
RPL27A
108Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YF34H0YF34_HUMAN
60S ribosomal protein L27a
RPL27A
42Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PJD9E9PJD9_HUMAN
60S ribosomal protein L27a
RPL27A
91Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PKT2E9PKT2_HUMAN
60S ribosomal protein L27a
RPL27A
41Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U14968 mRNA Translation: AAA85656.1
AB020236 Genomic DNA Translation: BAA77361.1
AK311767 mRNA Translation: BAG34710.1
CH471064 Genomic DNA Translation: EAW68619.1
BC005326 mRNA Translation: AAH05326.1
BC020169 mRNA Translation: AAH20169.1
AB007178 Genomic DNA Translation: BAA25837.1

The Consensus CDS (CCDS) project

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CCDSi
CCDS7790.1

Protein sequence database of the Protein Information Resource

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PIRi
S55914

NCBI Reference Sequences

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RefSeqi
NP_000981.1, NM_000990.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000314138; ENSP00000346015; ENSG00000166441

Database of genes from NCBI RefSeq genomes

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GeneIDi
6157

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:6157

UCSC genome browser

More...
UCSCi
uc001mgs.5 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14968 mRNA Translation: AAA85656.1
AB020236 Genomic DNA Translation: BAA77361.1
AK311767 mRNA Translation: BAG34710.1
CH471064 Genomic DNA Translation: EAW68619.1
BC005326 mRNA Translation: AAH05326.1
BC020169 mRNA Translation: AAH20169.1
AB007178 Genomic DNA Translation: BAA25837.1
CCDSiCCDS7790.1
PIRiS55914
RefSeqiNP_000981.1, NM_000990.4

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4BXFX-ray2.05C/D32-50[»]
4UG0electron microscopy-La1-148[»]
4V6Xelectron microscopy5.00Ca1-148[»]
5AJ0electron microscopy3.50Aa1-148[»]
5LKSelectron microscopy3.60La1-148[»]
5T2Celectron microscopy3.60U1-148[»]
6EK0electron microscopy2.90La1-148[»]
6IP5electron microscopy3.902U1-148[»]
6IP6electron microscopy4.502U1-148[»]
6IP8electron microscopy3.902U1-148[»]
6OLEelectron microscopy3.10b2-148[»]
6OLFelectron microscopy3.90b2-148[»]
6OLGelectron microscopy3.40Aa2-148[»]
6OLIelectron microscopy3.50b2-148[»]
6OLZelectron microscopy3.90Aa2-148[»]
6OM0electron microscopy3.10b2-148[»]
6OM7electron microscopy3.70b2-148[»]
6QZPelectron microscopy2.90La2-148[»]
SMRiP46776
ModBaseiSearch...

Protein-protein interaction databases

BioGridi112076, 176 interactors
CORUMiP46776
DIPiDIP-33121N
IntActiP46776, 46 interactors
MINTiP46776
STRINGi9606.ENSP00000346015

PTM databases

iPTMnetiP46776
PhosphoSitePlusiP46776
SwissPalmiP46776

Polymorphism and mutation databases

BioMutaiRPL27A

2D gel databases

SWISS-2DPAGEiP46776

Proteomic databases

EPDiP46776
jPOSTiP46776
MassIVEiP46776
MaxQBiP46776
PaxDbiP46776
PeptideAtlasiP46776
PRIDEiP46776
ProteomicsDBi55758
TopDownProteomicsiP46776

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000314138; ENSP00000346015; ENSG00000166441
GeneIDi6157
KEGGihsa:6157
UCSCiuc001mgs.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6157
DisGeNETi6157

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RPL27A
HGNCiHGNC:10329 RPL27A
HPAiHPA060776
HPA063379
MIMi603637 gene
neXtProtiNX_P46776
OpenTargetsiENSG00000166441
PharmGKBiPA34708

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1742 Eukaryota
COG0200 LUCA
GeneTreeiENSGT00390000005534
HOGENOMiHOG000231263
InParanoidiP46776
KOiK02900
OMAiWGRVGQH
OrthoDBi1445443at2759
PhylomeDBiP46776
TreeFamiTF313742

Enzyme and pathway databases

ReactomeiR-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
RPL27A human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
RPL27A

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
6157

Pharos

More...
Pharosi
P46776

Protein Ontology

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PROi
PR:P46776

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000166441 Expressed in 131 organ(s), highest expression level in ectocervix
ExpressionAtlasiP46776 baseline and differential
GenevisibleiP46776 HS

Family and domain databases

HAMAPiMF_01341 Ribosomal_L15, 1 hit
InterProiView protein in InterPro
IPR036227 L18e/L15P_sf
IPR030878 Ribosomal_L15
IPR001196 Ribosomal_L15_CS
IPR021131 Ribosomal_L18e/L15P
PfamiView protein in Pfam
PF00828 Ribosomal_L27A, 1 hit
SUPFAMiSSF52080 SSF52080, 1 hit
PROSITEiView protein in PROSITE
PS00475 RIBOSOMAL_L15, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRL27A_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P46776
Secondary accession number(s): B2R4B3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: January 23, 2007
Last modified: September 18, 2019
This is version 178 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Ribosomal proteins
    Ribosomal proteins families and list of entries
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