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1 to 25 of 114  Show
  1. 1
    "Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart."
    Wu S., Moomaw C.R., Tomer K.B., Falck J.R., Zeldin D.C.
    J. Biol. Chem. 271:3460-3468(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 1-20, FUNCTION, CATALYTIC ACTIVITY, PATHWAY, TISSUE SPECIFICITY, SUBCELLULAR LOCATION.
    Category: Function, Subcellular Location, Expression, Sequences.
    Tissue: Liver.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 10 other entries.

  2. 2
    Wu S., Zeldin D.C., Moomaw C.R., Tomer K.B., Falck J.R.
    Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: SEQUENCE REVISION TO 339 AND 378.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  3. 3
    "Involvement of CYP2J2 on the intestinal first-pass metabolism of antihistamine drug, astemizole."
    Matsumoto S., Hirama T., Matsubara T., Nagata K., Yamazoe Y.
    Drug Metab. Dispos. 30:1240-1245(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 3 other entries.

  4. 4
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANTS ALA-143; CYS-158; ASN-192; ASN-342 AND TYR-404, CHARACTERIZATION OF VARIANTS.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  5. 5
    NIEHS SNPs program
    Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANT SER-49.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  6. 6
    "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Category: Sequences.
    Tissue: Corpus callosum.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 12927 other entries.

  7. 7
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Category: Sequences.
    Tissue: Skin.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50448 other entries.

  8. 8
    "Identification of 13-hydroxy-14,15-epoxyeicosatrienoic acid as an acid-stable endothelium-derived hyperpolarizing factor in rabbit arteries."
    Chawengsub Y., Gauthier K.M., Nithipatikom K., Hammock B.D., Falck J.R., Narsimhaswamy D., Campbell W.B.
    J. Biol. Chem. 284:31280-31290(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, CATALYTIC ACTIVITY, PATHWAY, TISSUE SPECIFICITY.
    Category: Function, Expression.
    Source: UniProtKB/Swiss-Prot (reviewed).
  9. 9
    Cited for: FUNCTION, CATALYTIC ACTIVITY.
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 3 other entries.

  10. 10
    "CYP2J2 and CYP2C19 are the major enzymes responsible for metabolism of albendazole and fenbendazole in human liver microsomes and recombinant P450 assay systems."
    Wu Z., Lee D., Joo J., Shin J.H., Kang W., Oh S., Lee D.Y., Lee S.J., Yea S.S., Lee H.S., Lee T., Liu K.H.
    Antimicrob. Agents Chemother. 57:5448-5456(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION AS ALBENDAZOLE MONOOXYGENASE (HYDROXYLATION), CATALYTIC ACTIVITY.
    Category: Function, PTM / Processing.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 7 other entries.

  11. 11
    "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
    Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.
    J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: Sequences.
    Tissue: Liver.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 11549 other entries.

  12. 12
    "Stereoselective epoxidation of the last double bond of polyunsaturated fatty acids by human cytochromes P450."
    Lucas D., Goulitquer S., Marienhagen J., Fer M., Dreano Y., Schwaneberg U., Amet Y., Corcos L.
    J. Lipid Res. 51:1125-1133(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, CATALYTIC ACTIVITY, PATHWAY.
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 7 other entries.

  13. 13
    "Specific dehydrogenation of 3-methylindole and epoxidation of naphthalene by recombinant human CYP2F1 expressed in lymphoblastoid cells."
    Lanza D.L., Code E., Crespi C.L., Gonzalez F.J., Yost G.S.
    Drug Metab. Dispos. 27:798-803(1999) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-211022.

    This publication is mapped to 9 other entries.

  14. 14
    "Role of polymorphic human CYP2B6 in cyclophosphamide bioactivation."
    Xie H.J., Yasar U., Lundgren S., Griskevicius L., Terelius Y., Hassan M., Rane A.
    Pharmacogenomics J. 3:53-61(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-211022.

    This publication is mapped to 13 other entries.

  15. 15
    "Role of activator protein-1 in the down-regulation of the human CYP2J2 gene in hypoxia."
    Marden N.Y., Fiala-Beer E., Xiang S.H., Murray M.
    Biochem. J. 373:669-680(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: role of activator protein-1 in the down-regulation of the human CYP2J2 gene in hypoxia.
    Source: GeneRIF:1573.

    This publication is mapped to 4 other entries.

  16. 16
    "Cytochrome P450 2J2 polymorphism in healthy Caucasians and those with diabetes mellitus."
    Pucci L., Lucchesi D., Chirulli V., Penno G., Johansson I., Gervasi P., Del Prato S., Longo V.
    Am J Pharmacogenomics 3:355-358(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: The CYP2J2*6 allele is rare in the Caucasian population and no association is inferred between this allelic variant and type 1 or type 2 diabetic complications; Observational study of genotype prevalence and gene-disease association. (HuGE Navigator). [GeneRIF:1573]. Not Associated with diabetes, type 2; hypertension; diabetes, type 1. [GAD:121169].
    Source: GeneRIF:1573, GAD:121169.

    This publication is mapped to 4 other entries.

  17. 17
    "Identification of Val117 and Arg372 as critical amino acid residues for the activity difference between human CYP2A6 and CYP2A13 in coumarin 7-hydroxylation."
    He X.Y., Shen J., Hu W.Y., Ding X., Lu A.Y., Hong J.Y.
    Arch. Biochem. Biophys. 427:143-153(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-211022.

    This publication is mapped to 9 other entries.

  18. 18
    "Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway."
    Seubert J., Yang B., Bradbury J.A., Graves J., Degraff L.M., Gabel S., Gooch R., Foley J., Newman J., Mao L., Rockman H.A., Hammock B.D., Murphy E., Zeldin D.C.
    Circ. Res. 95:506-514(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Transgenic mice overexpressing human CYP2J2 have improved postischemic recovery of left ventricular function.
    Source: GeneRIF:1573.

    This publication is mapped to 8 other entries.

  19. 19
    "Metabolism of retinoids and arachidonic acid by human and mouse cytochrome P450 1b1."
    Choudhary D., Jansson I., Stoilov I., Sarfarazi M., Schenkman J.B.
    Drug Metab. Dispos. 32:840-847(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-211022.

    This publication is cited by 1 and mapped to 17 other entries.

  20. 20
    "Enhancement of cardiac L-type Ca2+ currents in transgenic mice with cardiac-specific overexpression of CYP2J2."
    Xiao Y.F., Ke Q., Seubert J.M., Bradbury J.A., Graves J., Degraff L.M., Falck J.R., Krausz K., Gelboin H.V., Morgan J.P., Zeldin D.C.
    Mol. Pharmacol. 66:1607-1616(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Overexpressoin of CYP2J2 in transgenic mice increases l-type calcium channles in cardiomyocytes.
    Source: GeneRIF:1573.

    This publication is mapped to 4 other entries.

  21. 21
    "Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2."
    Spiecker M., Darius H., Hankeln T., Soufi M., Sattler A.M., Schaefer J.R., Node K., Borgel J., Mugge A., Lindpaintner K., Huesing A., Maisch B., Zeldin D.C., Liao J.K.
    Circulation 110:2132-2136(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: Associated with CARDIOVASCULAR: atherosclerosis, coronary. [GAD:121170]. Observational study of gene-disease association. (HuGE Navigator); a functionally relevant polymorphism of the CYP2J2 gene is independently associated with an increased risk of coronary artery disease. [GeneRIF:1573].
    Source: GAD:121170, GeneRIF:1573.

    This publication is mapped to 4 other entries.

  22. 22
    "Identification and functional characterization of novel CYP2J2 variants: G312R variant causes loss of enzyme catalytic activity."
    Lee S.S., Jeong H.E., Liu K.H., Ryu J.Y., Moon T., Yoon C.N., Oh S.J., Yun C.H., Shin J.G.
    Pharmacogenet. Genomics 15:105-113(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: characterization of novel CYP2J2 variants that cause loss of enzyme catalytic activity; Observational study of genotype prevalence. (HuGE Navigator).
    Source: GeneRIF:1573.

    This publication is mapped to 4 other entries.

  23. 23
    "Single nucleotide polymorphisms in the CYP2J2 and CYP2C8 genes and the risk of hypertension."
    King L.M., Gainer J.V., David G.L., Dai D., Goldstein J.A., Brown N.J., Zeldin D.C.
    Pharmacogenet. Genomics 15:7-13(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: Associated with CARDIOVASCULAR: hypertension. [GAD:121173]. Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator); there is an association between CYP2J2*7 (but not CYP2C8*3) genotype and hypertension in Caucasian males and Caucasians without a family history of hypertension. [GeneRIF:1573].
    Source: GeneRIF:1573, GAD:121173.

    This publication is mapped to 9 other entries.

  24. 24
    "Characterization of a c-Jun-responsive module in the 5'-flank of the human CYP2J2 gene that regulates transactivation."
    Marden N.Y., Murray M.
    Biochem. J. 391:631-640(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: The c-Jun-responsive module between -122 and -50 in the CYP2J2 proximal promoter contains an atypical AP-1 element at -105/-95 that has a major role in c-Jun transactivation and acts in conjunction with the -56/-63 element to regulate expression.
    Source: GeneRIF:1573.

    This publication is mapped to 4 other entries.

  25. 25
    "CYP2J2*7 single nucleotide polymorphism in a Chinese population."
    Wang H., Jiang Y., Liu Y., Lin C., Cheng G., Chen X., Hao B., Tan W., Lin D., He F.
    Clin. Chim. Acta 365:125-128(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Observational study of genotype prevalence. (HuGE Navigator).
    Source: GeneRIF:1573.

    This publication is mapped to 4 other entries.

1 to 25 of 114  Show
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