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Entry version 159 (13 Nov 2019)
Sequence version 1 (10 May 2004)
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Protein

60S ribosomal protein L26

Gene

RPL26

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the large ribosomal subunit.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Protein family/group databases

MoonProt database of moonlighting proteins

More...
MoonProti
P61254

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
60S ribosomal protein L26
Alternative name(s):
Large ribosomal subunit protein uL241 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RPL26
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:10327 RPL26

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
603704 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P61254

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Diamond-Blackfan anemia 11 (DBA11)1 Publication
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionA form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies.
Related information in OMIM

Keywords - Diseasei

Diamond-Blackfan anemia

Organism-specific databases

DisGeNET

More...
DisGeNETi
6154

GeneReviews a resource of expert-authored, peer-reviewed disease descriptions.

More...
GeneReviewsi
RPL26

MalaCards human disease database

More...
MalaCardsi
RPL26
MIMi614900 phenotype

Open Targets

More...
OpenTargetsi
ENSG00000161970

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...
Orphaneti
124 Blackfan-Diamond anemia

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA34705

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
P61254

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RPL26

Domain mapping of disease mutations (DMDM)

More...
DMDMi
47117765

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001307871 – 14560S ribosomal protein L26Add BLAST145

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki136Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei139PhosphothreonineCombined sources1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
P61254

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
P61254

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
P61254

MaxQB - The MaxQuant DataBase

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MaxQBi
P61254

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P61254

PeptideAtlas

More...
PeptideAtlasi
P61254

PRoteomics IDEntifications database

More...
PRIDEi
P61254

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
57287

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
P61254

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P61254

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P61254

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P61254

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000161970 Expressed in 91 organ(s), highest expression level in female gonad

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P61254 baseline and differential

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB037301
HPA030449

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the large ribosomal subunit (Probable).

Interacts with DHX33 (PubMed:26100019).

1 Publication1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
112073, 131 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
P61254

Database of interacting proteins

More...
DIPi
DIP-33198N

Protein interaction database and analysis system

More...
IntActi
P61254, 57 interactors

Molecular INTeraction database

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MINTi
P61254

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000463784

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P61254

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG3401 Eukaryota
COG0198 LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00390000014165

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000216571

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
P61254

KEGG Orthology (KO)

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KOi
K02898

Identification of Orthologs from Complete Genome Data

More...
OMAi
VRIMRGD

Database of Orthologous Groups

More...
OrthoDBi
1488916at2759

Database for complete collections of gene phylogenies

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PhylomeDBi
P61254

TreeFam database of animal gene trees

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TreeFami
TF300236

Family and domain databases

Conserved Domains Database

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CDDi
cd06089 KOW_RPL26, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
2.30.30.30, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_01326_A Ribosomal_L24_A, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005824 KOW
IPR041988 KOW_RPL26/RPL24
IPR014722 Rib_L2_dom2
IPR005825 Ribosomal_L24/26_CS
IPR005756 Ribosomal_L26/L24P_euk/arc
IPR008991 Translation_prot_SH3-like_sf

The PANTHER Classification System

More...
PANTHERi
PTHR11143 PTHR11143, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00467 KOW, 1 hit
PF16906 Ribosomal_L26, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00739 KOW, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50104 SSF50104, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01080 rplX_A_E, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01108 RIBOSOMAL_L24, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

P61254-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKFNPFVTSD RSKNRKRHFN APSHIRRKIM SSPLSKELRQ KYNVRSMPIR
60 70 80 90 100
KDDEVQVVRG HYKGQQIGKV VQVYRKKYVI YIERVQREKA NGTTVHVGIH
110 120 130 140
PSKVVITRLK LDKDRKKILE RKAKSRQVGK EKGKYKEETI EKMQE
Length:145
Mass (Da):17,258
Last modified:May 10, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i049D53AB4E3F46B6
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
J3QRC4J3QRC4_HUMAN
60S ribosomal protein L26
RPL26
135Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QQV1J3QQV1_HUMAN
60S ribosomal protein L26
RPL26
110Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QRI7J3QRI7_HUMAN
60S ribosomal protein L26
RPL26
107Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KSS0J3KSS0_HUMAN
60S ribosomal protein L26
RPL26
63Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KS10J3KS10_HUMAN
60S ribosomal protein L26
RPL26
63Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti133G → S in AAA60279 (Ref. 2) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X69392 mRNA Translation: CAA49189.1
L07287 Genomic DNA Translation: AAA60279.1
AB061829 Genomic DNA Translation: BAB79467.1
AK311804 mRNA Translation: BAG34747.1
CH471108 Genomic DNA Translation: EAW90053.1
CH471108 Genomic DNA Translation: EAW90054.1
CH471108 Genomic DNA Translation: EAW90057.1
BC071664 mRNA Translation: AAH71664.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS11142.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S33713

NCBI Reference Sequences

More...
RefSeqi
NP_000978.1, NM_000987.3
NP_001302459.1, NM_001315530.1
NP_001302460.1, NM_001315531.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000582556; ENSP00000463470; ENSG00000161970
ENST00000583011; ENSP00000462322; ENSG00000161970
ENST00000584164; ENSP00000463784; ENSG00000161970
ENST00000648839; ENSP00000498177; ENSG00000161970

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
6154

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:6154

UCSC genome browser

More...
UCSCi
uc002glh.2 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X69392 mRNA Translation: CAA49189.1
L07287 Genomic DNA Translation: AAA60279.1
AB061829 Genomic DNA Translation: BAB79467.1
AK311804 mRNA Translation: BAG34747.1
CH471108 Genomic DNA Translation: EAW90053.1
CH471108 Genomic DNA Translation: EAW90054.1
CH471108 Genomic DNA Translation: EAW90057.1
BC071664 mRNA Translation: AAH71664.1
CCDSiCCDS11142.1
PIRiS33713
RefSeqiNP_000978.1, NM_000987.3
NP_001302459.1, NM_001315530.1
NP_001302460.1, NM_001315531.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4UG0electron microscopy-LY1-145[»]
4V6Xelectron microscopy5.00CY1-145[»]
5AJ0electron microscopy3.50AY1-145[»]
5LKSelectron microscopy3.60LY1-145[»]
5T2Celectron microscopy3.60S1-145[»]
6EK0electron microscopy2.90LY1-145[»]
6IP5electron microscopy3.902S1-145[»]
6IP6electron microscopy4.502S1-145[»]
6IP8electron microscopy3.902S1-145[»]
6OLEelectron microscopy3.10Z1-134[»]
6OLFelectron microscopy3.90Z1-134[»]
6OLGelectron microscopy3.40AY1-127[»]
6OLIelectron microscopy3.50Z1-134[»]
6OLZelectron microscopy3.90AY1-127[»]
6OM0electron microscopy3.10Z1-134[»]
6OM7electron microscopy3.70Z1-134[»]
6QZPelectron microscopy2.90LY1-134[»]
SMRiP61254
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi112073, 131 interactors
CORUMiP61254
DIPiDIP-33198N
IntActiP61254, 57 interactors
MINTiP61254
STRINGi9606.ENSP00000463784

Protein family/group databases

MoonProtiP61254

PTM databases

iPTMnetiP61254
PhosphoSitePlusiP61254
SwissPalmiP61254

Polymorphism and mutation databases

BioMutaiRPL26
DMDMi47117765

Proteomic databases

EPDiP61254
jPOSTiP61254
MassIVEiP61254
MaxQBiP61254
PaxDbiP61254
PeptideAtlasiP61254
PRIDEiP61254
ProteomicsDBi57287
TopDownProteomicsiP61254

Genome annotation databases

EnsembliENST00000582556; ENSP00000463470; ENSG00000161970
ENST00000583011; ENSP00000462322; ENSG00000161970
ENST00000584164; ENSP00000463784; ENSG00000161970
ENST00000648839; ENSP00000498177; ENSG00000161970
GeneIDi6154
KEGGihsa:6154
UCSCiuc002glh.2 human

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
6154
DisGeNETi6154

GeneCards: human genes, protein and diseases

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GeneCardsi
RPL26
GeneReviewsiRPL26
HGNCiHGNC:10327 RPL26
HPAiCAB037301
HPA030449
MalaCardsiRPL26
MIMi603704 gene
614900 phenotype
neXtProtiNX_P61254
OpenTargetsiENSG00000161970
Orphaneti124 Blackfan-Diamond anemia
PharmGKBiPA34705

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG3401 Eukaryota
COG0198 LUCA
GeneTreeiENSGT00390000014165
HOGENOMiHOG000216571
InParanoidiP61254
KOiK02898
OMAiVRIMRGD
OrthoDBi1488916at2759
PhylomeDBiP61254
TreeFamiTF300236

Enzyme and pathway databases

ReactomeiR-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
RPL26 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
RPL26

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
6154
PharosiP61254

Protein Ontology

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PROi
PR:P61254

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000161970 Expressed in 91 organ(s), highest expression level in female gonad
ExpressionAtlasiP61254 baseline and differential

Family and domain databases

CDDicd06089 KOW_RPL26, 1 hit
Gene3Di2.30.30.30, 1 hit
HAMAPiMF_01326_A Ribosomal_L24_A, 1 hit
InterProiView protein in InterPro
IPR005824 KOW
IPR041988 KOW_RPL26/RPL24
IPR014722 Rib_L2_dom2
IPR005825 Ribosomal_L24/26_CS
IPR005756 Ribosomal_L26/L24P_euk/arc
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR11143 PTHR11143, 1 hit
PfamiView protein in Pfam
PF00467 KOW, 1 hit
PF16906 Ribosomal_L26, 1 hit
SMARTiView protein in SMART
SM00739 KOW, 1 hit
SUPFAMiSSF50104 SSF50104, 1 hit
TIGRFAMsiTIGR01080 rplX_A_E, 1 hit
PROSITEiView protein in PROSITE
PS01108 RIBOSOMAL_L24, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRL26_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P61254
Secondary accession number(s): B2R4F0
, D3DTR8, Q02877, Q6IPY2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: May 10, 2004
Last modified: November 13, 2019
This is version 159 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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Main funding by: National Institutes of Health

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