Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 143 (13 Nov 2019)
Sequence version 1 (16 Aug 2004)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

V-type proton ATPase subunit B, brain isoform

Gene

Atp6v1b2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase
Biological processHydrogen ion transport, Ion transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-1222556 ROS and RNS production in phagocytes
R-MMU-77387 Insulin receptor recycling
R-MMU-917977 Transferrin endocytosis and recycling
R-MMU-9639288 Amino acids regulate mTORC1
R-MMU-983712 Ion channel transport

Protein family/group databases

Transport Classification Database

More...
TCDBi
3.A.2.2.6 the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
V-type proton ATPase subunit B, brain isoform
Short name:
V-ATPase subunit B 2
Alternative name(s):
Endomembrane proton pump 58 kDa subunit
Vacuolar proton pump subunit B 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Atp6v1b2
Synonyms:Atp6b2, Vat2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:109618 Atp6v1b2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Morpholino knockdown in the whole cochlea, especially in hair cells and spiral ganglion neurons causes a dose-dependent hearing loss.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001446271 – 511V-type proton ATPase subunit B, brain isoformAdd BLAST511

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P62814

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P62814

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P62814

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P62814

PeptideAtlas

More...
PeptideAtlasi
P62814

PRoteomics IDEntifications database

More...
PRIDEi
P62814

2D gel databases

REPRODUCTION-2DPAGE

More...
REPRODUCTION-2DPAGEi
P62814

University College Dublin 2-DE Proteome Database

More...
UCD-2DPAGEi
P62814

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P62814

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P62814

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P62814

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Mainly expressed in the organ of Corti and spiral ganglion neurons, in both the early postnatal cochlea (P2) and the adult cochlea (P30).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000006273 Expressed in 309 organ(s), highest expression level in CA1 field of hippocampus

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P62814 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (main components: subunits A, B, C, D, E, and F) attached to an integral membrane V0 proton pore complex (main component: the proteolipid protein).

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
198262, 3 interactors

Protein interaction database and analysis system

More...
IntActi
P62814, 7 interactors

Molecular INTeraction database

More...
MINTi
P62814

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000006435

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P62814

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ATPase alpha/beta chains family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1351 Eukaryota
COG1156 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155068

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P62814

KEGG Orthology (KO)

More...
KOi
K02147

Identification of Orthologs from Complete Genome Data

More...
OMAi
ITEGQLY

Database of Orthologous Groups

More...
OrthoDBi
541116at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P62814

TreeFam database of animal gene trees

More...
TreeFami
TF300313

Family and domain databases

HAMAP database of protein families

More...
HAMAPi
MF_00310 ATP_synth_B_arch, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR020003 ATPase_a/bsu_AS
IPR004100 ATPase_F1/V1/A1_a/bsu_N
IPR000194 ATPase_F1/V1/A1_a/bsu_nucl-bd
IPR005723 ATPase_V1-cplx_bsu
IPR027417 P-loop_NTPase
IPR022879 V-ATPase_su_B/beta

The PANTHER Classification System

More...
PANTHERi
PTHR43389 PTHR43389, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00006 ATP-synt_ab, 1 hit
PF02874 ATP-synt_ab_N, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF039114 V-ATPsynth_beta/V-ATPase_B, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01040 V-ATPase_V1_B, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00152 ATPASE_ALPHA_BETA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P62814-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALRAMRGIV NGAAPELPVP TGGPMAGARE QALAVSRNYL SQPRLTYKTV
60 70 80 90 100
SGVNGPLVIL DHVKFPRYAE IVHLTLPDGT KRSGQVLEVS GSKAVVQVFE
110 120 130 140 150
GTSGIDAKKT SCEFTGDILR TPVSEDMLGR VFNGSGKPID RGPVVLAEDF
160 170 180 190 200
LDIMGQPINP QCRIYPEEMI QTGISAIDGM NSIARGQKIP IFSAAGLPHN
210 220 230 240 250
EIAAQICRQA GLVKKSKDVV DYSEENFAIV FAAMGVNMET ARFFKSDFEE
260 270 280 290 300
NGSMDNVCLF LNLANDPTIE RIITPRLALT TAEFLAYQCE KHVLVILTDM
310 320 330 340 350
SSYAEALREV SAAREEVPGR RGFPGYMYTD LATIYERAGR VEGRNGSITQ
360 370 380 390 400
IPILTMPNDD ITHPIPDLTG YITEGQIYVD RQLHNRQIYP PINVLPSLSR
410 420 430 440 450
LMKSAIGEGM TRKDHADVSN QLYACYAIGK DVQAMKAVVG EEALTSDDLL
460 470 480 490 500
YLEFLQKFEK NFITQGPYEN RTVYETLDIG WQLLRIFPKE MLKRIPQSTL
510
SEFYPRDSAK H
Length:511
Mass (Da):56,551
Last modified:August 16, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE116BF9A36EEF36B
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAE30303 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAE30526 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAE31441 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti22 – 23GG → RP in AAC52411 (PubMed:8741845).Curated2
Sequence conflicti36S → G in AAC52411 (PubMed:8741845).Curated1
Sequence conflicti80T → A in BAE35206 (PubMed:16141072).Curated1
Sequence conflicti85 – 86QV → AS in AAC52411 (PubMed:8741845).Curated2
Sequence conflicti262 – 264NLA → ILP in AAC52411 (PubMed:8741845).Curated3
Sequence conflicti270E → K in BAE35536 (PubMed:16141072).Curated1
Sequence conflicti270E → K in BAE35612 (PubMed:16141072).Curated1
Sequence conflicti276R → C in AAC52411 (PubMed:8741845).Curated1
Sequence conflicti300M → T in AAC52411 (PubMed:8741845).Curated1
Sequence conflicti304A → P in AAC52411 (PubMed:8741845).Curated1
Sequence conflicti318P → H in BAE35536 (PubMed:16141072).Curated1
Sequence conflicti318P → H in BAE35612 (PubMed:16141072).Curated1
Sequence conflicti365I → M in BAE40674 (PubMed:16141072).Curated1
Sequence conflicti371Y → C in BAE35206 (PubMed:16141072).Curated1
Sequence conflicti373T → I in BAE30303 (PubMed:16141072).Curated1
Sequence conflicti373T → I in BAE30526 (PubMed:16141072).Curated1
Sequence conflicti405A → P in AAC52411 (PubMed:8741845).Curated1
Sequence conflicti437A → V in BAE30197 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U13838 Genomic DNA Translation: AAC52411.1
Y12634 mRNA Translation: CAA73182.1
AK146499 mRNA Translation: BAE27215.1
AK151200 mRNA Translation: BAE30197.1
AK151322 mRNA Translation: BAE30303.1 Different initiation.
AK151586 mRNA Translation: BAE30526.1 Different initiation.
AK152718 mRNA Translation: BAE31441.1 Different initiation.
AK152766 mRNA Translation: BAE31479.1
AK159133 mRNA Translation: BAE34845.1
AK159153 mRNA Translation: BAE34860.1
AK159586 mRNA Translation: BAE35206.1
AK159701 mRNA Translation: BAE35300.1
AK159986 mRNA Translation: BAE35536.1
AK160080 mRNA Translation: BAE35612.1
AK160854 mRNA Translation: BAE36047.1
AK166669 mRNA Translation: BAE38930.1
AK168852 mRNA Translation: BAE40674.1
AK169155 mRNA Translation: BAE40934.1
AK169270 mRNA Translation: BAE41031.1
BC012497 mRNA Translation: AAH12497.1
BC046302 mRNA Translation: AAH46302.1
BC085300 mRNA Translation: AAH85300.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS40358.1

NCBI Reference Sequences

More...
RefSeqi
NP_031535.2, NM_007509.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000006435; ENSMUSP00000006435; ENSMUSG00000006273

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
11966

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:11966

UCSC genome browser

More...
UCSCi
uc009lww.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U13838 Genomic DNA Translation: AAC52411.1
Y12634 mRNA Translation: CAA73182.1
AK146499 mRNA Translation: BAE27215.1
AK151200 mRNA Translation: BAE30197.1
AK151322 mRNA Translation: BAE30303.1 Different initiation.
AK151586 mRNA Translation: BAE30526.1 Different initiation.
AK152718 mRNA Translation: BAE31441.1 Different initiation.
AK152766 mRNA Translation: BAE31479.1
AK159133 mRNA Translation: BAE34845.1
AK159153 mRNA Translation: BAE34860.1
AK159586 mRNA Translation: BAE35206.1
AK159701 mRNA Translation: BAE35300.1
AK159986 mRNA Translation: BAE35536.1
AK160080 mRNA Translation: BAE35612.1
AK160854 mRNA Translation: BAE36047.1
AK166669 mRNA Translation: BAE38930.1
AK168852 mRNA Translation: BAE40674.1
AK169155 mRNA Translation: BAE40934.1
AK169270 mRNA Translation: BAE41031.1
BC012497 mRNA Translation: AAH12497.1
BC046302 mRNA Translation: AAH46302.1
BC085300 mRNA Translation: AAH85300.1
CCDSiCCDS40358.1
RefSeqiNP_031535.2, NM_007509.3

3D structure databases

SMRiP62814
ModBaseiSearch...

Protein-protein interaction databases

BioGridi198262, 3 interactors
IntActiP62814, 7 interactors
MINTiP62814
STRINGi10090.ENSMUSP00000006435

Protein family/group databases

TCDBi3.A.2.2.6 the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily

PTM databases

iPTMnetiP62814
PhosphoSitePlusiP62814
SwissPalmiP62814

2D gel databases

REPRODUCTION-2DPAGEiP62814
UCD-2DPAGEiP62814

Proteomic databases

EPDiP62814
jPOSTiP62814
MaxQBiP62814
PaxDbiP62814
PeptideAtlasiP62814
PRIDEiP62814

Genome annotation databases

EnsembliENSMUST00000006435; ENSMUSP00000006435; ENSMUSG00000006273
GeneIDi11966
KEGGimmu:11966
UCSCiuc009lww.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
526
MGIiMGI:109618 Atp6v1b2

Phylogenomic databases

eggNOGiKOG1351 Eukaryota
COG1156 LUCA
GeneTreeiENSGT00940000155068
InParanoidiP62814
KOiK02147
OMAiITEGQLY
OrthoDBi541116at2759
PhylomeDBiP62814
TreeFamiTF300313

Enzyme and pathway databases

ReactomeiR-MMU-1222556 ROS and RNS production in phagocytes
R-MMU-77387 Insulin receptor recycling
R-MMU-917977 Transferrin endocytosis and recycling
R-MMU-9639288 Amino acids regulate mTORC1
R-MMU-983712 Ion channel transport

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Atp6v1b2 mouse

Protein Ontology

More...
PROi
PR:P62814

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000006273 Expressed in 309 organ(s), highest expression level in CA1 field of hippocampus
GenevisibleiP62814 MM

Family and domain databases

HAMAPiMF_00310 ATP_synth_B_arch, 1 hit
InterProiView protein in InterPro
IPR020003 ATPase_a/bsu_AS
IPR004100 ATPase_F1/V1/A1_a/bsu_N
IPR000194 ATPase_F1/V1/A1_a/bsu_nucl-bd
IPR005723 ATPase_V1-cplx_bsu
IPR027417 P-loop_NTPase
IPR022879 V-ATPase_su_B/beta
PANTHERiPTHR43389 PTHR43389, 1 hit
PfamiView protein in Pfam
PF00006 ATP-synt_ab, 1 hit
PF02874 ATP-synt_ab_N, 1 hit
PIRSFiPIRSF039114 V-ATPsynth_beta/V-ATPase_B, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR01040 V-ATPase_V1_B, 1 hit
PROSITEiView protein in PROSITE
PS00152 ATPASE_ALPHA_BETA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiVATB2_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P62814
Secondary accession number(s): O09045
, P50517, Q3TG74, Q3TL62, Q3TVK6, Q3TWR0, Q3U791, Q3U7C8, Q3U9Z0, Q3UAW7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: August 16, 2004
Last modified: November 13, 2019
This is version 143 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again