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Entry version 144 (18 Sep 2019)
Sequence version 1 (27 Sep 2004)
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Protein

40S ribosomal protein S21

Gene

RPS21

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72649 Translation initiation complex formation
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-HSA-72702 Ribosomal scanning and start codon recognition
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
40S ribosomal protein S21
Alternative name(s):
Small ribosomal subunit protein eS211 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RPS21
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:10409 RPS21

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
180477 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P63220

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Endoplasmic reticulum

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
6227

Open Targets

More...
OpenTargetsi
ENSG00000171858

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA34812

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RPS21

Domain mapping of disease mutations (DMDM)

More...
DMDMi
52783792

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001947301 – 8340S ribosomal protein S21Add BLAST83

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineCombined sources1 Publication1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki41Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei81N6-acetyllysineCombined sources1

Keywords - PTMi

Acetylation, Isopeptide bond, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P63220

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P63220

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
P63220

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P63220

PeptideAtlas

More...
PeptideAtlasi
P63220

PRoteomics IDEntifications database

More...
PRIDEi
P63220

ProteomicsDB human proteome resource

More...
ProteomicsDBi
57509

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
P63220

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P63220

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P63220

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P63220

Miscellaneous databases

CutDB - Proteolytic event database

More...
PMAP-CutDBi
P63220

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000171858 Expressed in 238 organ(s), highest expression level in thyroid gland

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P63220 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P63220 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA003371

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the 40S small ribosomal subunit.

3 Publications

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
112141, 129 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
P63220

Protein interaction database and analysis system

More...
IntActi
P63220, 15 interactors

Molecular INTeraction database

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MINTi
P63220

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000345957

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P63220

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3486 Eukaryota
ENOG4112266 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000017515

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000183557

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P63220

KEGG Orthology (KO)

More...
KOi
K02971

Identification of Orthologs from Complete Genome Data

More...
OMAi
CPRKCSA

Database of Orthologous Groups

More...
OrthoDBi
1571849at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P63220

TreeFam database of animal gene trees

More...
TreeFami
TF300167

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.1230.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001931 Ribosomal_S21e
IPR018279 Ribosomal_S21e_CS
IPR038579 Ribosomal_S21e_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10442 PTHR10442, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01249 Ribosomal_S21e, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF002148 Ribosomal_S21e, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00996 RIBOSOMAL_S21E, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

P63220-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQNDAGEFVD LYVPRKCSAS NRIIGAKDHA SIQMNVAEVD KVTGRFNGQF
60 70 80
KTYAICGAIR RMGESDDSIL RLAKADGIVS KNF
Length:83
Mass (Da):9,111
Last modified:September 27, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6794AC1292A06BD3
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8WVC2Q8WVC2_HUMAN
40S ribosomal protein S21
RPS21
81Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q9BYK1Q9BYK1_HUMAN
40S ribosomal protein S21
RPS21 hCG_41768
90Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q9BYK2Q9BYK2_HUMAN
40S ribosomal protein S21
RPS21 hCG_41768
66Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
L04483 mRNA Translation: AAA99893.1
AJ250907 Genomic DNA Translation: CAB83213.1
AB061843 Genomic DNA Translation: BAB79481.1
AL121832 Genomic DNA No translation available.
AB007157 Genomic DNA Translation: BAA25821.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS13497.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S34108

NCBI Reference Sequences

More...
RefSeqi
NP_001015.1, NM_001024.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000343986; ENSP00000345957; ENSG00000171858

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
6227

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:6227

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L04483 mRNA Translation: AAA99893.1
AJ250907 Genomic DNA Translation: CAB83213.1
AB061843 Genomic DNA Translation: BAB79481.1
AL121832 Genomic DNA No translation available.
AB007157 Genomic DNA Translation: BAA25821.1
CCDSiCCDS13497.1
PIRiS34108
RefSeqiNP_001015.1, NM_001024.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4UG0electron microscopy-SV1-83[»]
4V6Xelectron microscopy5.00AV1-83[»]
5A2Qelectron microscopy3.90V1-83[»]
5AJ0electron microscopy3.50BV1-83[»]
5FLXelectron microscopy3.90V1-83[»]
5LKSelectron microscopy3.60SV1-83[»]
5OA3electron microscopy4.30V1-83[»]
5T2Celectron microscopy3.60AC1-83[»]
5VYCX-ray6.00V1/V2/V3/V4/V5/V61-83[»]
6EK0electron microscopy2.90SV1-83[»]
6G18electron microscopy3.60V1-83[»]
6G4Selectron microscopy4.00V1-83[»]
6G51electron microscopy4.10V1-83[»]
6G53electron microscopy4.50V1-83[»]
6G5Helectron microscopy3.60V1-83[»]
6G5Ielectron microscopy3.50V1-83[»]
6IP5electron microscopy3.903A1-83[»]
6IP6electron microscopy4.503A1-83[»]
6IP8electron microscopy3.903A1-83[»]
6OLEelectron microscopy3.10SV1-82[»]
6OLFelectron microscopy3.90SV1-82[»]
6OLGelectron microscopy3.40BV1-81[»]
6OLIelectron microscopy3.50SV1-82[»]
6OLZelectron microscopy3.90BV1-81[»]
6OM0electron microscopy3.10SV1-82[»]
6OM7electron microscopy3.70SV1-82[»]
6QZPelectron microscopy2.90SV1-83[»]
SMRiP63220
ModBaseiSearch...

Protein-protein interaction databases

BioGridi112141, 129 interactors
CORUMiP63220
IntActiP63220, 15 interactors
MINTiP63220
STRINGi9606.ENSP00000345957

PTM databases

iPTMnetiP63220
PhosphoSitePlusiP63220
SwissPalmiP63220

Polymorphism and mutation databases

BioMutaiRPS21
DMDMi52783792

Proteomic databases

EPDiP63220
jPOSTiP63220
MassIVEiP63220
PaxDbiP63220
PeptideAtlasiP63220
PRIDEiP63220
ProteomicsDBi57509
TopDownProteomicsiP63220

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
6227
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000343986; ENSP00000345957; ENSG00000171858
GeneIDi6227
KEGGihsa:6227

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6227
DisGeNETi6227

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RPS21
HGNCiHGNC:10409 RPS21
HPAiHPA003371
MIMi180477 gene
neXtProtiNX_P63220
OpenTargetsiENSG00000171858
PharmGKBiPA34812

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3486 Eukaryota
ENOG4112266 LUCA
GeneTreeiENSGT00390000017515
HOGENOMiHOG000183557
InParanoidiP63220
KOiK02971
OMAiCPRKCSA
OrthoDBi1571849at2759
PhylomeDBiP63220
TreeFamiTF300167

Enzyme and pathway databases

ReactomeiR-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72649 Translation initiation complex formation
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-HSA-72702 Ribosomal scanning and start codon recognition
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
RPS21 human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
RPS21

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
6227

Pharos

More...
Pharosi
P63220
PMAP-CutDBiP63220

Protein Ontology

More...
PROi
PR:P63220

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000171858 Expressed in 238 organ(s), highest expression level in thyroid gland
ExpressionAtlasiP63220 baseline and differential
GenevisibleiP63220 HS

Family and domain databases

Gene3Di3.30.1230.20, 1 hit
InterProiView protein in InterPro
IPR001931 Ribosomal_S21e
IPR018279 Ribosomal_S21e_CS
IPR038579 Ribosomal_S21e_sf
PANTHERiPTHR10442 PTHR10442, 1 hit
PfamiView protein in Pfam
PF01249 Ribosomal_S21e, 1 hit
PIRSFiPIRSF002148 Ribosomal_S21e, 1 hit
PROSITEiView protein in PROSITE
PS00996 RIBOSOMAL_S21E, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRS21_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P63220
Secondary accession number(s): P35265
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 27, 2004
Last sequence update: September 27, 2004
Last modified: September 18, 2019
This is version 144 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Ribosomal proteins
    Ribosomal proteins families and list of entries
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