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Entry version 150 (03 Jul 2019)
Sequence version 2 (07 Dec 2004)
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Protein

DNA-directed RNA polymerase I subunit RPA1

Gene

RpI1

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I. A bridging helix emanates from RPA1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol I by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition (By similarity).By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi66ZincBy similarity1
Metal bindingi69ZincBy similarity1
Metal bindingi75ZincBy similarity1
Metal bindingi78ZincBy similarity1
Metal bindingi565Magnesium; catalyticBy similarity1
Metal bindingi567Magnesium; catalyticBy similarity1
Metal bindingi569Magnesium; catalyticBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionNucleotidyltransferase, Transferase
Biological processTranscription
LigandMagnesium, Metal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-73762 RNA Polymerase I Transcription Initiation
R-DME-73772 RNA Polymerase I Promoter Escape

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DNA-directed RNA polymerase I subunit RPA1 (EC:2.7.7.6)
Short name:
RNA polymerase I subunit A1
Alternative name(s):
DNA-directed RNA polymerase I largest subunit
DNA-directed RNA polymerase I subunit A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RpI1
Synonyms:RPA1
ORF Names:CG10122
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0019938 RpI1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

DNA-directed RNA polymerase, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000739261 – 1642DNA-directed RNA polymerase I subunit RPA1Add BLAST1642

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1364Phosphoserine1 Publication1
Modified residuei1365Phosphoserine1 Publication1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated.By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P91875

PRoteomics IDEntifications database

More...
PRIDEi
P91875

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P91875

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0019938 Expressed in 31 organ(s), highest expression level in embryo

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P91875 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
62365, 6 interactors

Protein interaction database and analysis system

More...
IntActi
P91875, 1 interactor

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0086640

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P91875

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni939 – 951Bridging helixBy similarityAdd BLAST13

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1333 – 1426Asp-richAdd BLAST94

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RNA polymerase beta' chain family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0262 Eukaryota
COG0086 LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P91875

KEGG Orthology (KO)

More...
KOi
K02999

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P91875

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.132.30, 1 hit
1.10.274.100, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR015699 DNA-dir_RNA_pol1_lsu
IPR000722 RNA_pol_asu
IPR006592 RNA_pol_N
IPR007080 RNA_pol_Rpb1_1
IPR007066 RNA_pol_Rpb1_3
IPR042102 RNA_pol_Rpb1_3_sf
IPR007083 RNA_pol_Rpb1_4
IPR007081 RNA_pol_Rpb1_5
IPR038120 Rpb1_funnel_sf

The PANTHER Classification System

More...
PANTHERi
PTHR19376:SF11 PTHR19376:SF11, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04997 RNA_pol_Rpb1_1, 1 hit
PF00623 RNA_pol_Rpb1_2, 1 hit
PF04983 RNA_pol_Rpb1_3, 1 hit
PF05000 RNA_pol_Rpb1_4, 1 hit
PF04998 RNA_pol_Rpb1_5, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00663 RPOLA_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P91875-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGSKRAMDVH MFPSDLEFAV FTDQEIRKLS VVKVITGITF DALGHAIPGG
60 70 80 90 100
LYDIRMGSYG RCMDPCGTCL KLQDCPGHMG HIELGTPVYN PFFIKFVQRL
110 120 130 140 150
LCIFCLHCYK LQMKDHECEI IMLQLRLIDA GYIIEAQELE LFKSEIVCQN
160 170 180 190 200
TENLVAIKNG DMVHPHIAAM YKLLEKNEKN SSNSTKTSCS LRTAITHSAL
210 220 230 240 250
QRLGKKCRHC NKSMRFVRYM HRRLVFYVTL ADIKERVGTG AETGGQNKVI
260 270 280 290 300
FADECRRYLR QIYANYPELL KLLVPVLGLS NTDLTQGDRS PVDLFFMDTL
310 320 330 340 350
PVTPPRARPL NMVGDMLKGN PQTDIYINII ENNHVLNVVL KYMKGGQEKL
360 370 380 390 400
TEEAKAAYQT LKGETAHEKL YTAWLALQMS VDVLLDVNMS REMKSGEGLK
410 420 430 440 450
QIIEKKSGLI RSHMMGKRVN YAARTVITPD PNINVDEIGI PDIFAKKLSY
460 470 480 490 500
PVPVTEWNVT ELRKMVMNGP DVHPGANYIQ DKNGFTTYIP ADNASKRESL
510 520 530 540 550
AKLLLSNPKD GIKIVHRHVL NGDVLLLNRQ PSLHKPSIMG HKARILHGEK
560 570 580 590 600
TFRLHYSNCK AYNADFDGDE MNAHYPQSEV ARAEAYNLVN VASNYLVPKD
610 620 630 640 650
GTPLGGLIQD HVISGVKLSI RGRFFNREDY QQLVFQGLSQ LKKDIKLLPP
660 670 680 690 700
TILKPAVLWS GKQILSTIII NIIPEGYERI NLDSFAKIAG KNWNVSRPRP
710 720 730 740 750
PICGTNPEGN DLSESQVQIR NGELLVGVLD KQQYGATTYG LIHCMYELYG
760 770 780 790 800
GDVSTLLLTA FTKVFTFFLQ LEGFTLGVKD ILVTDVADRK RRKIIRECRN
810 820 830 840 850
VGNSAVAAAL ELEDEPPHDE LVEKMEAAYV KDSKFRVLLD RKYKSLLDGY
860 870 880 890 900
TNDINSTCLP RGLITKFPSN NLQLMVLSGA KGSMVNTMQI SCLLGQIELE
910 920 930 940 950
GKRPPLMISG KSLPSFTSFE TSPKSGGFID GRFMTGIQPQ DFFFHCMAGR
960 970 980 990 1000
EGLIDTAVKT SRSGYLQRCL IKHLEGLSVH YDLTVRDSDN SVVQFLYGED
1010 1020 1030 1040 1050
GLDILKSKFF NDKFCADFLT QNATAILRPA QLQLMKDEEQ LAKVQRHEKH
1060 1070 1080 1090 1100
IRSWEKKKPA KLRAAFTHFS EELREEVEVK RPNEINSKTG RRRFDEGLLK
1110 1120 1130 1140 1150
LWKKADAEDK ALYRKKYARC PDPTVAVYKQ DLYYGSVSER TRKLITDYAK
1160 1170 1180 1190 1200
RKPALKETIA DIMRVKTIKS LAAPGEPVGL IAAQSIGEPS TQMTLNTFHF
1210 1220 1230 1240 1250
AGRGEMNVTL GIPRLREILM LASSNIKTPS MDIPIKPGQQ HQAEKLRINL
1260 1270 1280 1290 1300
NSVTLANLLE YVHVSTGLTL DPERSYEYDM RFQFLPREVY KEDYGVRPKH
1310 1320 1330 1340 1350
IIKYMHQTFF KQLIRAILKV SNASRTTKIV VIDDKKDADK DDDNDLDNGD
1360 1370 1380 1390 1400
EVGRSKAKAN DDDSSDDNDD DDATGVKLKQ RKTDEKDYDD PDDVEELHDA
1410 1420 1430 1440 1450
NDDDDEAEDE DDEEKGQDGN DNDGDDKAVE RLLSNDMVKA YTYDKENHLW
1460 1470 1480 1490 1500
CQVKLNLSVR YQKPDLTSII RELAGKSVVH QVQHIKRAII YKGNDDDQLL
1510 1520 1530 1540 1550
KTDGINIGEM FQHNKILDLN RLYSNDIHAI ARTYGIEAAS QVIVKEVSNV
1560 1570 1580 1590 1600
FKVYGITVDR RHLSLIADYM TFDGTFQPLS RKGMEHSSSP LQQMSFESSL
1610 1620 1630 1640
QFLKSAAGFG RADELSSPSS RLMVGLPVRN GTGAFELLTK IC
Length:1,642
Mass (Da):185,410
Last modified:December 7, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB05DB5C4A5149F9A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti407S → C in CAA70321 (PubMed:9065685).Curated1
Sequence conflicti430D → AY in CAA70321 (PubMed:9065685).Curated1
Sequence conflicti461 – 462EL → DV in CAA70321 (PubMed:9065685).Curated2
Sequence conflicti758L → V in CAA70321 (PubMed:9065685).Curated1
Sequence conflicti1042A → V in CAA70321 (PubMed:9065685).Curated1
Sequence conflicti1085I → V in CAA70321 (PubMed:9065685).Curated1
Sequence conflicti1315 – 1316RA → PPP (PubMed:9065685).Curated2
Sequence conflicti1341D → E in AAF58234 (PubMed:10731132).Curated1
Sequence conflicti1494N → T in AAF58234 (PubMed:10731132).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Y09103 Genomic DNA Translation: CAA70321.1
AE013599 Genomic DNA Translation: AAF58234.1
AY121632 mRNA Translation: AAM51959.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T13803

NCBI Reference Sequences

More...
RefSeqi
NP_523743.1, NM_079019.3

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
36617

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG10122

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y09103 Genomic DNA Translation: CAA70321.1
AE013599 Genomic DNA Translation: AAF58234.1
AY121632 mRNA Translation: AAM51959.1
PIRiT13803
RefSeqiNP_523743.1, NM_079019.3

3D structure databases

SMRiP91875
ModBaseiSearch...

Protein-protein interaction databases

BioGridi62365, 6 interactors
IntActiP91875, 1 interactor
STRINGi7227.FBpp0086640

PTM databases

iPTMnetiP91875

Proteomic databases

PaxDbiP91875
PRIDEiP91875

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi36617
KEGGidme:Dmel_CG10122

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
36617
FlyBaseiFBgn0019938 RpI1

Phylogenomic databases

eggNOGiKOG0262 Eukaryota
COG0086 LUCA
InParanoidiP91875
KOiK02999
PhylomeDBiP91875

Enzyme and pathway databases

ReactomeiR-DME-73762 RNA Polymerase I Transcription Initiation
R-DME-73772 RNA Polymerase I Promoter Escape

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
RpI1 fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
36617

Protein Ontology

More...
PROi
PR:P91875

Gene expression databases

BgeeiFBgn0019938 Expressed in 31 organ(s), highest expression level in embryo
GenevisibleiP91875 DM

Family and domain databases

Gene3Di1.10.132.30, 1 hit
1.10.274.100, 1 hit
InterProiView protein in InterPro
IPR015699 DNA-dir_RNA_pol1_lsu
IPR000722 RNA_pol_asu
IPR006592 RNA_pol_N
IPR007080 RNA_pol_Rpb1_1
IPR007066 RNA_pol_Rpb1_3
IPR042102 RNA_pol_Rpb1_3_sf
IPR007083 RNA_pol_Rpb1_4
IPR007081 RNA_pol_Rpb1_5
IPR038120 Rpb1_funnel_sf
PANTHERiPTHR19376:SF11 PTHR19376:SF11, 1 hit
PfamiView protein in Pfam
PF04997 RNA_pol_Rpb1_1, 1 hit
PF00623 RNA_pol_Rpb1_2, 1 hit
PF04983 RNA_pol_Rpb1_3, 1 hit
PF05000 RNA_pol_Rpb1_4, 1 hit
PF04998 RNA_pol_Rpb1_5, 1 hit
SMARTiView protein in SMART
SM00663 RPOLA_N, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRPA1_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P91875
Secondary accession number(s): Q8MRE2, Q9V732
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: December 7, 2004
Last modified: July 3, 2019
This is version 150 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
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