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1 to 19 of 19  Show
  1. 6
    "BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C."
    Kato Y., Kravchenko V.V., Tapping R.I., Han J., Ulevitch R.J., Lee J.-D.
    EMBO J. 16:7054-7066(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION AT THR-293; THR-300 AND SER-419, FUNCTION, MUTAGENESIS OF THR-293; THR-300 AND SER-419.
    Category: Function, Pathology & Biotech, PTM / Processing.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 other entries.

  2. 7
    "Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation."
    Han J., Jiang Y., Li Z., Kravchenko V.V., Ulevitch R.J.
    Nature 386:296-299(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION AT THR-293; THR-300 AND SER-419, FUNCTION, MUTAGENESIS OF THR-293; THR-300 AND SER-419.
    Category: Function, Pathology & Biotech, PTM / Processing.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 5 other entries.

  3. 10
    "Big mitogen-activated kinase regulates multiple members of the MEF2 protein family."
    Kato Y., Zhao M., Morikawa A., Sugiyama T., Chakravortty D., Koide N., Yoshida T., Tapping R.I., Yang Y., Yokochi T., Lee J.D.
    J. Biol. Chem. 275:18534-18540(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION BY MAPK7.
    Category: PTM / Processing.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 other entries.

  4. 12
    "Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis."
    Okamoto S., Li Z., Ju C., Scholzke M.N., Mathews E., Cui J., Salvesen G.S., Bossy-Wetzel E., Lipton S.A.
    Proc. Natl. Acad. Sci. U.S.A. 99:3974-3979(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEOLYTIC PROCESSING AT ASP-432, FUNCTION, MUTAGENESIS OF ASP-432.
    Category: Function, Pathology & Biotech, PTM / Processing.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 other entries.

  5. 13
    "Phosphorylation and alternative pre-mRNA splicing converge to regulate myocyte enhancer factor 2C activity."
    Zhu B., Gulick T.
    Mol. Cell. Biol. 24:8264-8275(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION AT SER-396, IDENTIFICATION BY MASS SPECTROMETRY, MUTAGENESIS OF SER-396, FUNCTION OF ISOFORMS.
    Category: Function, Pathology & Biotech, PTM / Processing, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 4 other entries.

  6. 15
    "Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates."
    Gocke C.B., Yu H., Kang J.
    J. Biol. Chem. 280:5004-5012(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUMOYLATION.
    Category: PTM / Processing.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 20 other entries.

  7. 17
    "Association with class IIa histone deacetylases upregulates the sumoylation of MEF2 transcription factors."
    Gregoire S., Yang X.-J.
    Mol. Cell. Biol. 25:2273-2287(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUMOYLATION AT LYS-391.
    Category: PTM / Processing.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 other entries.

  8. 18
    "Myocyte enhancer factor 2 acetylation by p300 enhances its DNA binding activity, transcriptional activity, and myogenic differentiation."
    Ma K., Chan J.K., Zhu G., Wu Z.
    Mol. Cell. Biol. 25:3575-3582(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION AT LYS-116; LYS-119; LYS-234; LYS-239; LYS-252 AND LYS-264, INTERACTION WITH EP300, FUNCTION, DNA-BINDING, MUTAGENESIS OF LYS-116; LYS-119; LYS-234; LYS-239; LYS-252 AND LYS-264.
    Category: Function, Pathology & Biotech, PTM / Processing, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 5 other entries.

  9. 19
    "Phosphorylation-facilitated sumoylation of MEF2C negatively regulates its transcriptional activity."
    Kang J., Gocke C.B., Yu H.
    BMC Biochem. 7:5-5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUMOYLATION AT LYS-391, MUTAGENESIS OF LYS-391 AND SER-396.
    Category: Pathology & Biotech, PTM / Processing.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 5 other entries.

  10. 21
    "Toward a comprehensive characterization of a human cancer cell phosphoproteome."
    Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., Mohammed S.
    J. Proteome Res. 12:260-271(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-222; SER-228; SER-240 AND SER-445, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Tissue: Erythroleukemia.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 13410 other entries.

  11. 28
    "p38 and extracellular signal-regulated kinases regulate the myogenic program at multiple steps."
    Wu Z., Woodring P.J., Bhakta K.S., Tamura K., Wen F., Feramisco J.R., Karin M., Wang J.Y., Puri P.L.
    Mol. Cell. Biol. 20:3951-3964(2000) [PubMed] [Europe PMC] [Abstract]
    Category: Function, PTM / Processing.
    Annotation: Pathway. [Reactome:R-HSA-199938, Reactome:R-HSA-448838]. Phosphorylation. [iPTMnet:Q06413].
    Source: Reactome:R-HSA-199938, Reactome:R-HSA-448838, iPTMnet:Q06413.

    This publication is mapped to 6 other entries.

  12. 39
    "Overexpression of myocyte enhancer factor 2 and histone hyperacetylation in hepatocellular carcinoma."
    Bai X., Wu L., Liang T., Liu Z., Li J., Li D., Xie H., Yin S., Yu J., Lin Q., Zheng S.
    J. Cancer Res. Clin. Oncol. 134:83-91(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Function, PTM / Processing.
    Annotation: Overexpression of MEF2C is associated with hepatocellular carcinoma.
    Source: GeneRIF:4208.

    This publication is mapped to 13 other entries.

  13. 40
    "Brain-derived neurotrophic factor stimulates the transcriptional and neuroprotective activity of myocyte-enhancer factor 2C through an ERK1/2-RSK2 signaling cascade."
    Wang Y., Liu L., Xia Z.
    J. Neurochem. 102:957-966(2007) [PubMed] [Europe PMC] [Abstract]
    Category: PTM / Processing.
    Annotation: Phosphorylation.
    Source: iPTMnet:Q06413.

    This publication is mapped to 1 other entry.

  14. 65
    "Skeletal myosin light chain kinase regulates skeletal myogenesis by phosphorylation of MEF2C."
    Al Madhoun A.S., Mehta V., Li G., Figeys D., Wiper-Bergeron N., Skerjanc I.S.
    EMBO J. 30:2477-2489(2011) [PubMed] [Europe PMC] [Abstract]
    Category: PTM / Processing, Interaction.
    Source: IntAct:Q06413, PhosphoSitePlus:Q06413.

    This publication is mapped to 52 other entries.

  15. 97
    "Phosphorylation-dependent degradation of MEF2C contributes to regulate G2/M transition."
    Badodi S., Baruffaldi F., Ganassi M., Battini R., Molinari S.
    Cell Cycle 14:1517-1528(2015) [PubMed] [Europe PMC] [Abstract]
    Category: PTM / Processing.
    Annotation: MEF2C regulates the expression of G2/M checkpoint genes (14-3-3gamma Gadd45b and p21) and the sub-cellular localization of CYCLIN B1.
    Source: GeneRIF:4208.

    This publication is mapped to 7 other entries.

  16. 121
    "High Sensitivity Quantitative Proteomics Using Automated Multidimensional Nano-flow Chromatography and Accumulated Ion Monitoring on Quadrupole-Orbitrap-Linear Ion Trap Mass Spectrometer."
    Cifani P., Kentsis A.
    Mol. Cell Proteomics 16:2006-2016(2017) [PubMed] [Europe PMC] [Abstract]
    Category: PTM / Processing.
    Annotation: Combined with automated 2D nano-scale chromatography Accumulated ion monitoring achieved subattomolar limits of detection of endogenous proteins in complex biological proteomes. This allowed quantitation of absolute abundance of the human transcription factor MEF2C at approximately 100 molecules/cell and determination of its phosphorylation stoichiometry from as little as 1 mug of extracts isolated from 10 000 human ...
    Source: GeneRIF:4208.

    This publication is mapped to 6 other entries.

  17. 125
    Category: PTM / Processing.
    Annotation: High levels of phosphorylation of S222 of MEF2C are associated with primary chemotherapy resistance in an independent cohort of cytogenetically normal and Acute Myeloid Leukemia. [GeneRIF:4208]. Phosphorylation. [iPTMnet:Q06413].
    Source: GeneRIF:4208, iPTMnet:Q06413.

    This publication is mapped to 6 other entries.

  18. 126
    "LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia."
    Tarumoto Y., Lu B., Somerville T.D.D., Huang Y.H., Milazzo J.P., Wu X.S., Klingbeil O., El Demerdash O., Shi J., Vakoc C.R.
    Mol. Cell 69:1017-1027.e6(2018) [PubMed] [Europe PMC] [Abstract]
    Category: Function, PTM / Processing.
    Annotation: Targeting of LKB1 or SIK3 diminishes histone acetylation at MEF2C-bound enhancers and deprives leukemia cells of the output of this essential TF.
    Source: GeneRIF:4208.

    This publication is mapped to 21 other entries.

  19. 133
    "Phosphorylation of the MADS-Box transcription factor MEF2C enhances its DNA binding activity."
    Molkentin J.D., Li L., Olson E.N.
    J. Biol. Chem. 271:17199-17204(1996) [PubMed] [Europe PMC] [Abstract]
    Category: PTM / Processing.
    Annotation: Phosphorylation.
    Source: iPTMnet:Q06413.
1 to 19 of 19  Show
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