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Entry version 132 (16 Oct 2019)
Sequence version 1 (01 Oct 1996)
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Protein

Condensin complex subunit 3

Gene

cnd3

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. The condensin complex probably also plays a role during interphase.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle, Cell division, DNA condensation, Mitosis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-SPO-2514853 Condensation of Prometaphase Chromosomes

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Condensin complex subunit 3
Alternative name(s):
CAPG homolog
p100
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:cnd3
ORF Names:SPCC188.03
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284812 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002485 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome III

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
FungiDB:SPCC188.03

Schizosaccharomyces pombe database

More...
PomBasei
SPCC188.03 cnd3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Cytoplasm, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000950451 – 875Condensin complex subunit 3Add BLAST875

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q10429

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q10429

PRoteomics IDEntifications database

More...
PRIDEi
Q10429

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q10429

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the condensin complex, which contains the cut14/smc2 and cut3/smc2 heterodimer, and three non SMC subunits that probably regulate the complex: cnd1, cnd2 and cnd3.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
Q9Y7R32EBI-1149700,EBI-1149594

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
275693, 9 interactors

Protein interaction database and analysis system

More...
IntActi
Q10429, 1 interactor

STRING: functional protein association networks

More...
STRINGi
4896.SPCC188.03.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1875
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q10429

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati55 – 76HEAT 1Add BLAST22
Repeati77 – 113HEAT 2Add BLAST37
Repeati117 – 154HEAT 3Add BLAST38
Repeati157 – 192HEAT 4Add BLAST36
Repeati222 – 259HEAT 5Add BLAST38
Repeati379 – 418HEAT 6Add BLAST40
Repeati516 – 554HEAT 7Add BLAST39
Repeati556 – 591HEAT 8Add BLAST36
Repeati740 – 778HEAT 9Add BLAST39

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CND3 (condensin subunit 3) family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q10429

KEGG Orthology (KO)

More...
KOi
K06678

Identification of Orthologs from Complete Genome Data

More...
OMAi
CHFLNML

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q10429

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR027165 CND3
IPR025977 Cnd3_C

The PANTHER Classification System

More...
PANTHERi
PTHR14418 PTHR14418, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12719 Cnd3, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q10429-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSCIQIISSS QTSIAGHRKL CNKLFTLRTQ EGFETDILRA LNIILTVKKG
60 70 80 90 100
NSNADRVLRF LVTFVNYLQQ KDPEIDIVQP ILKHILRGLD AKDKTVRYRC
110 120 130 140 150
CQIIARVVNC VKEIDDDLYN TLKEKLLSRV LDRESIVRLE AVVALSRLQE
160 170 180 190 200
DTGDEENDVR NILLFLLQND PSSEVRRSVL LNIEVSNSTL PFILERARDV
210 220 230 240 250
DAANRKCVYA RVLPKIGDFR YLSIKKRVRI LKWGLNDRDE SVEKAAADML
260 270 280 290 300
AYQWIENADN NLLELLERLD VSNNSDVAVL AIKKFFDVRV DSLSQLEFPE
310 320 330 340 350
QFWLELTAES SLLARTFNEI CIEKNYTDLL DKMPEVVQLT YYIERQYVSL
360 370 380 390 400
RDKSSYDESC FIIEQLLYIG LSQDMVDEIG RRKLLKSLTN SLSTMALPDS
410 420 430 440 450
LISLHIELLR KLCSSENDFC SLLVEIITEV FEQGHSQNQT EEQGNSNAPE
460 470 480 490 500
LNKNDYEGEE ITVSQKSPSP SLPPNELNEP EPDDMDGYKE AFNELRCLSY
510 520 530 540 550
VQCLFENITS SLNENLYMVD MLKTLIIPAV RSHDLPIREK GLECLSLVCL
560 570 580 590 600
LNADLAFENV PLYLHCYEKG SVVLKCTAIR TLTDMLIQHG KAKFTEYEDA
610 620 630 640 650
ISSILFEALG EFENAELQTL GAEAIAKLLV ILHYRDELFL KPLIIQYFEP
660 670 680 690 700
NTVDNHALRQ VLGYFFPVYA FGAHENQWRI ATIFCDALLS LLEIYRDLDE
710 720 730 740 750
DDVQLSIGHI AQQMLDWTDN EKLYERKTQT GDDYIALNHN VHLHLANMIF
760 770 780 790 800
ESLPNASEGK ERKFMISLLG KLKIPTDLPS SDYQRTKRKL ETYESHGFTM
810 820 830 840 850
DSTSLSILAK FERMLLQNEE ARSKFEETEE ERLMENAEEN EHAGAEAISG
860 870
EIIPDTVEAN MEDEEEVYVK QEEDL
Length:875
Mass (Da):100,491
Last modified:October 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i38A67C9A1A61A0CE
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB030214 Genomic DNA Translation: BAA82626.1
CU329672 Genomic DNA Translation: CAB41223.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T43522

NCBI Reference Sequences

More...
RefSeqi
NP_588207.1, NM_001023197.2

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
SPCC188.03.1; SPCC188.03.1:pep; SPCC188.03

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2539121

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
spo:SPCC188.03

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB030214 Genomic DNA Translation: BAA82626.1
CU329672 Genomic DNA Translation: CAB41223.1
PIRiT43522
RefSeqiNP_588207.1, NM_001023197.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5OQRX-ray2.61A/B1-823[»]
SMRiQ10429
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi275693, 9 interactors
IntActiQ10429, 1 interactor
STRINGi4896.SPCC188.03.1

PTM databases

iPTMnetiQ10429

Proteomic databases

MaxQBiQ10429
PaxDbiQ10429
PRIDEiQ10429

Genome annotation databases

EnsemblFungiiSPCC188.03.1; SPCC188.03.1:pep; SPCC188.03
GeneIDi2539121
KEGGispo:SPCC188.03

Organism-specific databases

EuPathDBiFungiDB:SPCC188.03
PomBaseiSPCC188.03 cnd3

Phylogenomic databases

InParanoidiQ10429
KOiK06678
OMAiCHFLNML
PhylomeDBiQ10429

Enzyme and pathway databases

ReactomeiR-SPO-2514853 Condensation of Prometaphase Chromosomes

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q10429

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR027165 CND3
IPR025977 Cnd3_C
PANTHERiPTHR14418 PTHR14418, 1 hit
PfamiView protein in Pfam
PF12719 Cnd3, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCND3_SCHPO
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q10429
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 16, 2019
This is version 132 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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