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Entry version 110 (18 Sep 2019)
Sequence version 1 (24 May 2005)
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Protein

Protein raptor homolog

Gene

raptor

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DDI-1632852 Macroautophagy
R-DDI-165159 mTOR signalling
R-DDI-166208 mTORC1-mediated signalling
R-DDI-3371571 HSF1-dependent transactivation
R-DDI-380972 Energy dependent regulation of mTOR by LKB1-AMPK
R-DDI-5628897 TP53 Regulates Metabolic Genes
R-DDI-8943724 Regulation of PTEN gene transcription

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein raptor homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:raptor
ORF Names:DDB_G0270398
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDictyostelium discoideum (Slime mold)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri44689 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002195 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componentsi: Chromosome 1, Unassembled WGS sequence

Organism-specific databases

Dictyostelium discoideum online informatics resource

More...
dictyBasei
DDB_G0270398 raptor

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003682341 – 1509Protein raptor homologAdd BLAST1509

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q55BR7

PRoteomics IDEntifications database

More...
PRIDEi
Q55BR7

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Part of a complex, TORC1, consisting of tor, raptor and lst8.

1 Publication

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
44689.DDB0234064

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati1184 – 1225WD 1Add BLAST42
Repeati1229 – 1270WD 2Add BLAST42
Repeati1284 – 1328WD 3Add BLAST45
Repeati1332 – 1371WD 4Add BLAST40
Repeati1377 – 1418WD 5Add BLAST42
Repeati1420 – 1460WD 6Add BLAST41
Repeati1468 – 1507WD 7Add BLAST40

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi31 – 61Poly-AsnAdd BLAST31
Compositional biasi79 – 85Poly-Asn7
Compositional biasi319 – 326Poly-Asn8
Compositional biasi349 – 356Poly-Ser8
Compositional biasi1012 – 1030Poly-AsnAdd BLAST19
Compositional biasi1034 – 1055Poly-AsnAdd BLAST22

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the WD repeat RAPTOR family.Curated

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1517 Eukaryota
ENOG410XQKJ LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q55BR7

KEGG Orthology (KO)

More...
KOi
K07204

Identification of Orthologs from Complete Genome Data

More...
OMAi
HQFEDHL

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q55BR7

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.10, 1 hit
2.130.10.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR004083 Raptor
IPR029347 Raptor_N
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR12848 PTHR12848, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14538 Raptor_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01302 Raptor_N, 1 hit
SM00320 WD40, 6 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit
SSF50978 SSF50978, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50294 WD_REPEATS_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q55BR7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDKSYNFSSS NLANSSGLHN SINSNNVNGV NNINNNNNNN NNNNNNNNNN
60 70 80 90 100
NNNENVNNHN NVSNISNTHQ QAKKKEKYNN NNNKNKPFFG EERHKDNATP
110 120 130 140 150
DVQKTKIAKW RMRERMKTVS VALVLCLNIG VDPPDVIKTF PCARMECWFD
160 170 180 190 200
PSTQPPQKAL DLIGKTLQAQ YEKWQSKARY KQSLDPTVEE VKKLCLSLRR
210 220 230 240 250
NAKDERVLFH YNGHGVPKPT TNGEIWVFNR NFTQYIPLSI YELQTWMGTP
260 270 280 290 300
SIYVFDCSAA GLIINWFNQF AEQRDKELER FSGNNQNNNQ NNNQNSNQNN
310 320 330 340 350
QNNTTNSTNG NTNGNNQQNN NNSNNNSSNN SNTNSPNMGS SNSVNNNQSG
360 370 380 390 400
SSSSSSHQRD CILLAACSAN EILPMNPDFP ADMFTACLTT PIRIALRWFC
410 420 430 440 450
SHSILTGITA DMLDKIPGNL SSRRTPLGEL NWIFTAVTDT IAWNVLPRHL
460 470 480 490 500
FQKLFRQDLL VASLFRNYLL AERIMRSANC TPISCPRLPP TYQHAMWQAW
510 520 530 540 550
DLAVDLVISQ LPTLLADPNA EFKSSPFFTE QLTAFEVWLE FGSEHKDPPA
560 570 580 590 600
QLPIVLQVLL SQAHRLRALV LLGKFLDLGP WAVNLALCVG IFPYVLKLLQ
610 620 630 640 650
SPAGDLRHIL VFIWAKILAL DKSCQLDLVK ENGHAYFISV LSSPQIPADQ
660 670 680 690 700
RTMSAFVLST ICNNCRPGQN ACLIGNLLPI CLSQLNDPDP MVRRWMILCM
710 720 730 740 750
AKMWENFEEA KWAAIKENAH EKLCLLLTDV SPEVRASAVV ALGELIGGAE
760 770 780 790 800
GSEQRTNIEL NLALTLAVIT ADCSPMVRKE LVISLSRIVS SYESNFVQVA
810 820 830 840 850
QEIAQEERLR AVLEAKRLEE SRKSKKRASV PKISDADHLN NNSDLYGNGS
860 870 880 890 900
QSSVYGCLWK IILNLCTDPF DQVANRAQSI VKRISSKFSM EELMSHNLIN
910 920 930 940 950
RTNFNFNNLN GSMNGLNSSG SGFLNSSNGN LGASMNGSNL NSSNNNLGGS
960 970 980 990 1000
SGGGFGLNNS NSSIRNTFVN ISRITNRDPR SPTKTKLGNQ RSPILTSSTN
1010 1020 1030 1040 1050
NVGTNLNGNQ LNLNNNNINN GNINNNNNNN SSINNNGNNI NNNGNGNNNN
1060 1070 1080 1090 1100
INNNNGLGNQ LANTFQSLSL SSGLGGNKTN KMSQSISSMN SSSQSLQNDF
1110 1120 1130 1140 1150
LMVSDSMPFE EDELYSDYYE WSCNYFSKPM MQSTGEDFES FESIEKKWKR
1160 1170 1180 1190 1200
QRNEMIIQES KEAVQNIIQQ PPKSFSQMTI FAEPNGQPIS HLQFHPFDNI
1210 1220 1230 1240 1250
LVVSDGLENI SVWNYDDGQR INTFNNCNMS GTRITSMKLV NDYDPSMIIT
1260 1270 1280 1290 1300
AADDGVVRIW RGYESNDTLK MVSSWRAFPE FATTGNDPIG RLVLDWKGDS
1310 1320 1330 1340 1350
GLVLVSGETP DSPKIRIWDV ERELGVQDIF IGTESVVTCM ANEKRGPLFS
1360 1370 1380 1390 1400
AGFSDGLVKL FDQRIPGKYS CVSTLTEHKS YIVNVSMPAS LGGKTVVSGS
1410 1420 1430 1440 1450
STGEIKFWQH SYECSSTTIH NNDVISSFSV HEYAPLIACG SQNQRIKIMN
1460 1470 1480 1490 1500
FTGEDVCTIR YHDGFLGQRI GPVSCVAFHP YNILMGAGAT DSIISIYNGD

SKSKSNVDW
Length:1,509
Mass (Da):167,888
Last modified:May 24, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i57C6706C874678DF
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAFI02000005 Genomic DNA Translation: EAL72549.1

NCBI Reference Sequences

More...
RefSeqi
XP_646764.1, XM_641672.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
EAL72549; EAL72549; DDB_G0270398

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
8617737

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ddi:DDB_G0270398

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000005 Genomic DNA Translation: EAL72549.1
RefSeqiXP_646764.1, XM_641672.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi44689.DDB0234064

Proteomic databases

PaxDbiQ55BR7
PRIDEiQ55BR7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEAL72549; EAL72549; DDB_G0270398
GeneIDi8617737
KEGGiddi:DDB_G0270398

Organism-specific databases

dictyBaseiDDB_G0270398 raptor

Phylogenomic databases

eggNOGiKOG1517 Eukaryota
ENOG410XQKJ LUCA
InParanoidiQ55BR7
KOiK07204
OMAiHQFEDHL
PhylomeDBiQ55BR7

Enzyme and pathway databases

ReactomeiR-DDI-1632852 Macroautophagy
R-DDI-165159 mTOR signalling
R-DDI-166208 mTORC1-mediated signalling
R-DDI-3371571 HSF1-dependent transactivation
R-DDI-380972 Energy dependent regulation of mTOR by LKB1-AMPK
R-DDI-5628897 TP53 Regulates Metabolic Genes
R-DDI-8943724 Regulation of PTEN gene transcription

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q55BR7

Family and domain databases

Gene3Di1.25.10.10, 1 hit
2.130.10.10, 3 hits
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR004083 Raptor
IPR029347 Raptor_N
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PANTHERiPTHR12848 PTHR12848, 1 hit
PfamiView protein in Pfam
PF14538 Raptor_N, 1 hit
SMARTiView protein in SMART
SM01302 Raptor_N, 1 hit
SM00320 WD40, 6 hits
SUPFAMiSSF48371 SSF48371, 1 hit
SSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS50294 WD_REPEATS_REGION, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRPTOR_DICDI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q55BR7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: May 24, 2005
Last modified: September 18, 2019
This is version 110 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
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