Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 93 (31 Jul 2019)
Sequence version 1 (29 Mar 2005)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein
Submitted name:

MKIAA4231 protein

Gene

Col3a1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
MKIAA4231 proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Col3a1Imported
Synonyms:mKIAA4231Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:88453 Col3a1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 26Sequence analysisAdd BLAST26
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500425492027 – 1467Sequence analysisAdd BLAST1441

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q5DTG2

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini36 – 93VWFCInterPro annotationAdd BLAST58
Domaini1233 – 1467Fibrillar collagen NC1InterPro annotationAdd BLAST235

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni100 – 1198DisorderedSequence analysisAdd BLAST1099

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi100 – 124Pro-richSequence analysisAdd BLAST25
Compositional biasi147 – 161PolarSequence analysisAdd BLAST15
Compositional biasi176 – 203Pro-richSequence analysisAdd BLAST28
Compositional biasi209 – 224Pro-richSequence analysisAdd BLAST16
Compositional biasi560 – 574Pro-richSequence analysisAdd BLAST15
Compositional biasi707 – 721Pro-richSequence analysisAdd BLAST15
Compositional biasi887 – 904Pro-richSequence analysisAdd BLAST18
Compositional biasi1182 – 1196Pro-richSequence analysisAdd BLAST15

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3544 Eukaryota
ENOG410XNMM LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000085654

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008160 Collagen
IPR000885 Fib_collagen_C
IPR001007 VWF_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01410 COLFI, 1 hit
PF01391 Collagen, 5 hits
PF00093 VWC, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00038 COLFI, 1 hit
SM00214 VWC, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51461 NC1_FIB, 1 hit
PS01208 VWFC_1, 1 hit
PS50184 VWFC_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

Q5DTG2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
YLDMMSFVQS GTWFLLTLLH PTLILAQQSN VDELGCSHLG QSYESRDVWK
60 70 80 90 100
PEPCQICVCD SGSVLCDDII CDEEPLDCPN PEIPFGECCA ICPQPSTPAP
110 120 130 140 150
VLPDGHGPQG PKGDPGPPGI PGRNGDPGLP GQPGLPGPPG SPGICESCPT
160 170 180 190 200
GGQNYSPQFD SYDVKSGVGG MGGYPGPAGP PGPPGPPGSS GHPGSPGSPG
210 220 230 240 250
YQGPPGEPGQ AGPAGPPGPP GALGPAGPAG KDGESGRPGR PGERGLPGPP
260 270 280 290 300
GIKGPAGMPG FPGMKGHRGF DGRNGEKGET GAPGLKGENG LPGDNGAPGP
310 320 330 340 350
MGPRGAPGER GRPGLPGAAG ARGNDGARGS DGQPGPPGPP GTAGFPGSPG
360 370 380 390 400
AKGEVGPAGS PGSNGSPGQR GEPGPQGHAG AQGPPGPPGN NGSPGGKGEM
410 420 430 440 450
GPAGIPGAPG LIGARGPPGP AGTNGIPGTR GPSGEPGKNG AKGEPGARGE
460 470 480 490 500
RGEAGSPGIP GPKGEDGKDG SPGEPGANGL PGAAGERGPS GFRGPAGPNG
510 520 530 540 550
IPGEKGPPGE RGGPGPAGPR GVAGEPGRDG TPGGPGIRGM PGSPGGPGND
560 570 580 590 600
GKPGPPGSQG ESGRPGPPGP SGPRGQPGVM GFPGPKGNDG APGKNGERGG
610 620 630 640 650
PGGPGLPGPA GKNGETGPQG PPGPTGPAGD KGDSGPPGPQ GLQGIPGTGG
660 670 680 690 700
PPGENGKPGE PGPKGEVGAP GAPGGKGDSG APGERGPPGT AGIPGARGGA
710 720 730 740 750
GPPGPEGGKG PAGPPGPPGA SGSPGLQGMP GERGGPGSPG PKGEKGEPGG
760 770 780 790 800
AGADGVPGKD GPRGPAGPIG PPGPAGQPGD KGEGGSPGLP GIAGPRGGPG
810 820 830 840 850
ERGEHGPPGP AGFPGAPGQN GEPGAKGERG APGEKGEGGP PGPAGPTGSS
860 870 880 890 900
GPAGPPGPQG VKGERGSPGG PGTAGFPGGR GLPGPPGNNG NPGPPGPSGA
910 920 930 940 950
PGKDGPPGPA GNSGSPGNPG IAGPKGDAGQ PGEKGPPGAQ GPPGSPGPLG
960 970 980 990 1000
IAGLTGARGL AGPPGMPGPR GSPGPQGIKG ESGKPGASGH NGERGPPGPQ
1010 1020 1030 1040 1050
GLPGQPGTAG EPGRDGNPGS DGQPGRDGSP GGKGDRGENG SPGAPGAPGH
1060 1070 1080 1090 1100
PGPPGPVGPS GKSGDRGETG PAGPSGAPGP AGARGAPGPQ GPRGDKGETG
1110 1120 1130 1140 1150
ERGSNGIKGH RGFPGNPGPP GSPGAAGHQG AIGSPGPAGP RGPVGPHGPP
1160 1170 1180 1190 1200
GKDGTSGHPG PIGPPGPRGN RGERGSEGSP GHPGQPGPPG PPGAPGPCCG
1210 1220 1230 1240 1250
GGAAAIAGVG GEKSGGFSPY YGDDPMDFKI NTEEIMSSLK SVNGQIESLI
1260 1270 1280 1290 1300
SPDGSRKNPA RNCRDLKFCH PELKSGEYWV DPNQGCKMDA IKVFCNMETG
1310 1320 1330 1340 1350
ETCINASPMT VPRKHWWTDS GAEKKHVWFG ESMNGGFQFS YGPPDLPEDV
1360 1370 1380 1390 1400
VDVQLAFLRL LSSRASQNIT YHCKNSIAYM DQASGNVKKS LKLMGSNEGE
1410 1420 1430 1440 1450
FKAEGNSKFT YTVLEDGCTK HTGEWSKTVF EYQTRKAMRL PIIDIAPYDI
1460
GGPDQEFGVD IGPVCFL
Length:1,467
Mass (Da):139,335
Last modified:March 29, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i73274A578803DCF8
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK220558 mRNA Translation: BAD90325.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK220558 mRNA Translation: BAD90325.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

MaxQBiQ5DTG2

Organism-specific databases

MGIiMGI:88453 Col3a1

Phylogenomic databases

eggNOGiKOG3544 Eukaryota
ENOG410XNMM LUCA
HOGENOMiHOG000085654

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Col3a1 mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Family and domain databases

InterProiView protein in InterPro
IPR008160 Collagen
IPR000885 Fib_collagen_C
IPR001007 VWF_dom
PfamiView protein in Pfam
PF01410 COLFI, 1 hit
PF01391 Collagen, 5 hits
PF00093 VWC, 1 hit
SMARTiView protein in SMART
SM00038 COLFI, 1 hit
SM00214 VWC, 1 hit
PROSITEiView protein in PROSITE
PS51461 NC1_FIB, 1 hit
PS01208 VWFC_1, 1 hit
PS50184 VWFC_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ5DTG2_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5DTG2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 29, 2005
Last sequence update: March 29, 2005
Last modified: July 31, 2019
This is version 93 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again