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1 to 25 of 35  Show
  1. 1
    "A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans."
    Mink M., Fogelgren B., Olszewski K., Maroy P., Csiszar K.
    Genomics 74:234-244(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), TISSUE SPECIFICITY.
    Category: Expression, Sequences.
    Tissue: Brain.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 17 other entries.

  2. 2
    "SARM1 isoforms nucleotide sequence."
    Bousson J.-C., Casteran C., Tiraby G.
    Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  3. 3
    "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."
    Nagase T., Ishikawa K., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.
    DNA Res. 5:31-39(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 127-724.
    Category: Sequences.
    Tissue: Brain.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 98 and mapped to 1 other entries.

  4. 4
    "Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response."
    Liberati N.T., Fitzgerald K.A., Kim D.H., Feinbaum R., Golenbock D.T., Ausubel F.M.
    Proc. Natl. Acad. Sci. U.S.A. 101:6593-6598(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 3 other entries.

  5. 5
    "The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling."
    Carty M., Goodbody R., Schroeder M., Stack J., Moynagh P.N., Bowie A.G.
    Nat. Immunol. 7:1074-1081(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH TICAM1.
    Category: Function, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 8 other entries.

  6. 6
    "DisSARMing Toll-like receptor signaling."
    O'Neill L.A.J.
    Nat. Immunol. 7:1023-1025(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).
  7. 7
    "MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival."
    Kim Y., Zhou P., Qian L., Chuang J.Z., Lee J., Li C., Iadecola C., Nathan C., Ding A.
    J. Exp. Med. 204:2063-2074(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY.
    Category: Expression.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 and mapped to 30 other entries.

  8. 8
    "Studies of SARM1 uncover similarities between immune and neuronal responses to danger."
    Dalod M.
    Sci. STKE 2007:PE73-PE73(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: REVIEW.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 and mapped to 3 other entries.

  9. 9
    Cited for: FUNCTION, SUBCELLULAR LOCATION, INDUCTION.
    Category: Function, Subcellular Location, Expression.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 18 other entries.

  10. 10
    "Targeting of pro-apoptotic TLR adaptor SARM to mitochondria: definition of the critical region and residues in the signal sequence."
    Panneerselvam P., Singh L.P., Ho B., Chen J., Ding J.L.
    Biochem. J. 442:263-271(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION, MITOCHONDRIAL TRANSIT PEPTIDE CLEAVAGE SITE, MUTAGENESIS OF LYS-11; ARG-14; ARG-22 AND ARG-27.
    Category: Function, Subcellular Location, Pathology & Biotech, PTM / Processing.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 5 other entries.

  11. 11
    "Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain."
    Deng L., Wang C., Spencer E., Yang L., Braun A., You J., Slaughter C., Pickart C., Chen Z.J.
    Cell 103:351-361(2000) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-2559572.

    This publication is cited by 1 and mapped to 14 other entries.

  12. 12
    "Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif."
    Kaiser W.J., Offermann M.K.
    J. Immunol. 174:4942-4952(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-2559572.

    This publication is mapped to 11 other entries.

  13. 13
    "SARM1: A candidate gene in the onset of hereditary infectious/inflammatory diseases."
    Mink M., Csiszar K.
    Clin. Immunol. 115:333-334(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Candidate gene in the onset of hereditary infectious/inflammatory diseases.
    Source: GeneRIF:23098.

    This publication is mapped to 4 other entries.

  14. 14
    "Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation."
    Cusson-Hermance N., Khurana S., Lee T.H., Fitzgerald K.A., Kelliher M.A.
    J. Biol. Chem. 280:36560-36566(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-2559572.

    This publication is mapped to 26 other entries.

  15. 15
    "Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response."
    Oganesyan G., Saha S.K., Guo B., He J.Q., Shahangian A., Zarnegar B., Perry A., Cheng G.
    Nature 439:208-211(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-2559572.

    This publication is cited by 1 and mapped to 38 other entries.

  16. 16
    "Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6."
    Hacker H., Redecke V., Blagoev B., Kratchmarova I., Hsu L.C., Wang G.G., Kamps M.P., Raz E., Wagner H., Hacker G., Mann M., Karin M.
    Nature 439:204-207(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-2559572.

    This publication is mapped to 49 other entries.

  17. 17
    "Retinoschisin (RS1), the protein encoded by the X-linked retinoschisis gene, is anchored to the surface of retinal photoreceptor and bipolar cells through its interactions with a Na/K ATPase-SARM1 complex."
    Molday L.L., Wu W.W., Molday R.S.
    J. Biol. Chem. 282:32792-32801(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location, Interaction.
    Annotation: confirmed the co-localization of retinoschisin with Na/K ATPase and SARM1 in photoreceptors and bipolar cells of retina tissue.
    Source: GeneRIF:23098.

    This publication is mapped to 20 other entries.

  18. 18
    "Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-beta-dependent pathways and increases expression of negative regulators of TLR signaling."
    Piao W., Song C., Chen H., Diaz M.A., Wahl L.M., Fitzgerald K.A., Li L., Medvedev A.E.
    J. Leukoc. Biol. 86:863-875(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-2559572.

    This publication is mapped to 17 other entries.

  19. 19
    "Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines."
    Tseng P.H., Matsuzawa A., Zhang W., Mino T., Vignali D.A., Karin M.
    Nat. Immunol. 11:70-75(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-2559572.

    This publication is mapped to 82 other entries.

  20. 20
    Category: Function, Pathology & Biotech.
    Annotation: Observational study of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:23098.

    This publication is mapped to 18812 other entries.

  21. 21
    "Direct binding of TRAF2 and TRAF6 to TICAM-1/TRIF adaptor participates in activation of the Toll-like receptor 3/4 pathway."
    Sasai M., Tatematsu M., Oshiumi H., Funami K., Matsumoto M., Hatakeyama S., Seya T.
    Mol. Immunol. 47:1283-1291(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-2559572.

    This publication is mapped to 10 other entries.

  22. 22
    "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."
    Bailey S.D., Xie C., Do R., Montpetit A., Diaz R., Mohan V., Keavney B., Yusuf S., Gerstein H.C., Engert J.C., Anand S.
    Diabetes Care 33:2250-2253(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: Observational study of gene-disease association gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator).
    Source: GeneRIF:23098.

    This publication is mapped to 18693 other entries.

  23. 23
    "Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph."
    Casabonne D., Reina O., Benavente Y., Becker N., Maynadie M., Foretova L., Cocco P., Gonzalez-Neira A., Nieters A., Boffetta P., Middeldorp J.M., de Sanjose S.
    Haematologica 96:323-327(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator).
    Source: GeneRIF:23098.

    This publication is mapped to 915 other entries.

  24. 24
    "T-cell death following immune activation is mediated by mitochondria-localized SARM."
    Panneerselvam P., Singh L.P., Selvarajan V., Chng W.J., Ng S.B., Tan N.S., Ho B., Chen J., Ding J.L.
    Cell Death Differ. 20:478-489(2013) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location.
    Annotation: SARM overexpression caused mitochondrial clustering which has also been observed in several cell death phenomenon.
    Source: GeneRIF:23098.

    This publication is mapped to 19 other entries.

  25. 25
    "SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria."
    Murata H., Sakaguchi M., Kataoka K., Huh N.H.
    Mol. Biol. Cell 24:2772-2784(2013) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: These results indicate that association of PINK1 with SARM1 and TRAF6 is an important step for mitophagy.
    Source: GeneRIF:23098.

    This publication is mapped to 6 other entries.

1 to 25 of 35  Show
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