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Entry version 106 (08 May 2019)
Sequence version 1 (01 Jun 2003)
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Protein

KAT8 regulatory NSL complex subunit 1

Gene

Kansl1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChromatin regulator

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-3214847 HATs acetylate histones

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
KAT8 regulatory NSL complex subunit 1
Alternative name(s):
NSL complex protein NSL1
Non-specific lethal 1 homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Kansl1
Synonyms:Kiaa1267, Nsl1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1923969 Kansl1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Centromere, Chromosome, Kinetochore, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002345661 – 1036KAT8 regulatory NSL complex subunit 1Add BLAST1036

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei104N6-acetyllysineBy similarity1
Modified residuei249PhosphoserineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki262Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei268PhosphoserineCombined sources1
Cross-linki331Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei922PhosphoserineBy similarity1
Modified residuei925PhosphoserineBy similarity1
Modified residuei934PhosphothreonineBy similarity1
Modified residuei976PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q80TG1

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q80TG1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q80TG1

PeptideAtlas

More...
PeptideAtlasi
Q80TG1

PRoteomics IDEntifications database

More...
PRIDEi
Q80TG1

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q80TG1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q80TG1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000018412 Expressed in 261 organ(s), highest expression level in dorsal pancreas

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q80TG1 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q80TG1 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L, HCFC1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, KAT8/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10.

Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1.

Interacts with KAT8; the interaction is direct (By similarity).

By similarity

GO - Molecular functioni

Protein-protein interaction databases

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-875 NSL histone acetyltransferase complex

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000102585

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q80TG1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni781 – 813Required for activation of KAT8 histone acetyltransferase activityBy similarityAdd BLAST33
Regioni814 – 1036Sufficient for interaction with KAT8By similarityAdd BLAST223

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili285 – 312Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IKZN Eukaryota
ENOG410ZYQQ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063688

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q80TG1

KEGG Orthology (KO)

More...
KOi
K18400

Database of Orthologous Groups

More...
OrthoDBi
191128at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026180 NSL1
IPR029332 PEHE_dom

The PANTHER Classification System

More...
PANTHERi
PTHR22443 PTHR22443, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15275 PEHE, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01300 PEHE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (5+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 5 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 5 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q80TG1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAAMAPALTD AAAEAHHIRF KLAPPSSTLS PGSAENNGNA NILISANGTK
60 70 80 90 100
RKAIAAEDPS LDFRNNPTKE DLGKLQPLVA SYLCSDVTSV PAKESLKLQG
110 120 130 140 150
VFSKQTVLKS HPLLSQSYEL RAELLGRQPV LEFSLENLRT MNTSGQTALP
160 170 180 190 200
QAPVNGLAKK LTKSSTHSDH DNSSSLNGGK RSLTSSSLQG GEVGGPDSGN
210 220 230 240 250
LKGGMTNCTL PHRSLDIQHT TLYSNNSTAN KSSVNSMDQP ALQGSSRLSP
260 270 280 290 300
STDSSSNLTN VKLEVKKSPL SSILFSALDS DTRITALLRR QADIEIRARR
310 320 330 340 350
LQKRLQVVQA KQVERHLQHQ LGGFLETTLS KLPNLESLRS RSQLMLTRKA
360 370 380 390 400
EAALRKAASE SATSEGLSNF LKSDSISEEL ERFTASGIAN LRCSEQAFDS
410 420 430 440 450
DVTDSSSGGE SDIEEEELTR ADPEQCHVPL KRRSEWRWAA DRAAIVSRWN
460 470 480 490 500
WLQAHVSDLE YRIRQQTDIY KQIRANKGLI VLGEAPFPDH TTDLLSLSSE
510 520 530 540 550
VKTDHGRDKL IESVSQPSEN HGILVSNITE SLSTKSCGAP RPVNGVVNSL
560 570 580 590 600
QPVLADQVPG DSSDAEEQLH KKQRLNLVSS SDGTCVAART RPVLTCKKRR
610 620 630 640 650
LVRPSSIVPL SKKVHRNVRS GCDVNPSCAL CGSGSVNTMP PEIHYEAPLL
660 670 680 690 700
ERLSQLDSCV HPVLAFPDDV PTSLHFQSML KSQWQNKPFD KIKPTKKFSL
710 720 730 740 750
KHRATMPCSL SDPVRKDRHK LVNSFLTTAM LKHHTDMSSP SYLTATHHPP
760 770 780 790 800
HSPLVRQLST SSDTSTPTSS GSQVAASTSQ PVRRRRGESS FDINNIVIPM
810 820 830 840 850
SVAATTRVEK LQYKEILTPS WREVDVQSLK GSPDEENEEI EDLSDAAFAA
860 870 880 890 900
LHAKCEEMER ARWLWTTSVP PQRRGSRSYR SSDGRTTPQL GSANPSTPQP
910 920 930 940 950
ASPDVSSSHS LSEFSHGQSP RSPISPELHS APLTPVARDS LRHLASEDTR
960 970 980 990 1000
CSTPELGLDE QSVQPWERRT FPLAYSPQAE CEEQLDAQDT AARCTRRTSG
1010 1020 1030
SKTGREAEVA PTSPPVVPLK SRHLAATVTA QRPAHR
Length:1,036
Mass (Da):113,179
Last modified:June 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF619B60DEEE93A62
GO
Isoform 2 (identifier: Q80TG1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     615-643: HRNVRSGCDVNPSCALCGSGSVNTMPPEI → GAQRTGLRSALILSRVGEPPSSPVNLQNY
     644-1036: Missing.

Note: No experimental confirmation available.
Show »
Length:643
Mass (Da):69,724
Checksum:i74B228E59E1B3DA6
GO
Isoform 3 (identifier: Q80TG1-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     478-510: Missing.
     615-643: HRNVRSGCDVNPSCALCGSGSVNTMPPEI → GAQRTGLRSALILSRVGEPPSSPVNLQNY
     644-1036: Missing.

Note: No experimental confirmation available.
Show »
Length:610
Mass (Da):66,180
Checksum:iEF19107E16ABE383
GO
Isoform 4 (identifier: Q80TG1-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     431-1036: Missing.

Note: No experimental confirmation available.
Show »
Length:430
Mass (Da):46,184
Checksum:i832BDE9011CBA181
GO
Isoform 5 (identifier: Q80TG1-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-770: Missing.
     771-779: GSQVAASTS → MCSLRSWNQ

Note: No experimental confirmation available.
Show »
Length:266
Mass (Da):29,518
Checksum:iEE0BA4E50B0A6286
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A2A5Y4A2A5Y4_MOUSE
KAT8 regulatory NSL complex subunit...
Kansl1 1700081L11Rik, mCG_141096
1,099Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B1AQV9B1AQV9_MOUSE
KAT8 regulatory NSL complex subunit...
Kansl1 1700081L11Rik
91Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti197D → N in BAE36437 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0183601 – 770Missing in isoform 5. 1 PublicationAdd BLAST770
Alternative sequenceiVSP_018361431 – 1036Missing in isoform 4. 1 PublicationAdd BLAST606
Alternative sequenceiVSP_018362478 – 510Missing in isoform 3. 1 PublicationAdd BLAST33
Alternative sequenceiVSP_018363615 – 643HRNVR…MPPEI → GAQRTGLRSALILSRVGEPP SSPVNLQNY in isoform 2 and isoform 3. 2 PublicationsAdd BLAST29
Alternative sequenceiVSP_018364644 – 1036Missing in isoform 2 and isoform 3. 2 PublicationsAdd BLAST393
Alternative sequenceiVSP_018365771 – 779GSQVAASTS → MCSLRSWNQ in isoform 5. 1 Publication9

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK122484 mRNA Translation: BAC65766.1
AK006970 mRNA Translation: BAB24813.1
AK037800 mRNA Translation: BAE20523.1
AK153679 mRNA Translation: BAE32141.1
AK161514 mRNA Translation: BAE36437.1
AL593843 Genomic DNA No translation available.
BC025052 mRNA Translation: AAH25052.1
BC043121 mRNA Translation: AAH43121.2
BC053389 mRNA Translation: AAH53389.2
BC054752 mRNA Translation: AAH54752.2
BC079594 mRNA Translation: AAH79594.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS48953.1 [Q80TG1-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001074514.1, NM_001081045.1 [Q80TG1-1]
XP_006534516.1, XM_006534453.3 [Q80TG1-1]
XP_011247610.1, XM_011249308.2 [Q80TG1-1]
XP_017170320.1, XM_017314831.1 [Q80TG1-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000018556; ENSMUSP00000018556; ENSMUSG00000018412 [Q80TG1-1]
ENSMUST00000106977; ENSMUSP00000102590; ENSMUSG00000018412 [Q80TG1-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
76719

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:76719

UCSC genome browser

More...
UCSCi
uc007lwj.1 mouse [Q80TG1-1]
uc007lwm.1 mouse [Q80TG1-3]
uc007lwn.1 mouse [Q80TG1-2]
uc007lwo.1 mouse [Q80TG1-4]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK122484 mRNA Translation: BAC65766.1
AK006970 mRNA Translation: BAB24813.1
AK037800 mRNA Translation: BAE20523.1
AK153679 mRNA Translation: BAE32141.1
AK161514 mRNA Translation: BAE36437.1
AL593843 Genomic DNA No translation available.
BC025052 mRNA Translation: AAH25052.1
BC043121 mRNA Translation: AAH43121.2
BC053389 mRNA Translation: AAH53389.2
BC054752 mRNA Translation: AAH54752.2
BC079594 mRNA Translation: AAH79594.1
CCDSiCCDS48953.1 [Q80TG1-1]
RefSeqiNP_001074514.1, NM_001081045.1 [Q80TG1-1]
XP_006534516.1, XM_006534453.3 [Q80TG1-1]
XP_011247610.1, XM_011249308.2 [Q80TG1-1]
XP_017170320.1, XM_017314831.1 [Q80TG1-1]

3D structure databases

SMRiQ80TG1
ModBaseiSearch...

Protein-protein interaction databases

ComplexPortaliCPX-875 NSL histone acetyltransferase complex
STRINGi10090.ENSMUSP00000102585

PTM databases

iPTMnetiQ80TG1
PhosphoSitePlusiQ80TG1

Proteomic databases

EPDiQ80TG1
jPOSTiQ80TG1
PaxDbiQ80TG1
PeptideAtlasiQ80TG1
PRIDEiQ80TG1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000018556; ENSMUSP00000018556; ENSMUSG00000018412 [Q80TG1-1]
ENSMUST00000106977; ENSMUSP00000102590; ENSMUSG00000018412 [Q80TG1-1]
GeneIDi76719
KEGGimmu:76719
UCSCiuc007lwj.1 mouse [Q80TG1-1]
uc007lwm.1 mouse [Q80TG1-3]
uc007lwn.1 mouse [Q80TG1-2]
uc007lwo.1 mouse [Q80TG1-4]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
284058
MGIiMGI:1923969 Kansl1

Rodent Unidentified Gene-Encoded large proteins database

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Rougei
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Phylogenomic databases

eggNOGiENOG410IKZN Eukaryota
ENOG410ZYQQ LUCA
GeneTreeiENSGT00530000063688
InParanoidiQ80TG1
KOiK18400
OrthoDBi191128at2759

Enzyme and pathway databases

ReactomeiR-MMU-3214847 HATs acetylate histones

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Kansl1 mouse

Protein Ontology

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PROi
PR:Q80TG1

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000018412 Expressed in 261 organ(s), highest expression level in dorsal pancreas
ExpressionAtlasiQ80TG1 baseline and differential
GenevisibleiQ80TG1 MM

Family and domain databases

InterProiView protein in InterPro
IPR026180 NSL1
IPR029332 PEHE_dom
PANTHERiPTHR22443 PTHR22443, 2 hits
PfamiView protein in Pfam
PF15275 PEHE, 1 hit
SMARTiView protein in SMART
SM01300 PEHE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKANL1_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q80TG1
Secondary accession number(s): A2A5Y5
, Q3TT88, Q3U5D8, Q3V3N3, Q7TMU3, Q80XP7, Q8R3L6, Q9D9G0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: June 1, 2003
Last modified: May 8, 2019
This is version 106 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
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